JP2008020918A5 - - Google Patents
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- JP2008020918A5 JP2008020918A5 JP2007183697A JP2007183697A JP2008020918A5 JP 2008020918 A5 JP2008020918 A5 JP 2008020918A5 JP 2007183697 A JP2007183697 A JP 2007183697A JP 2007183697 A JP2007183697 A JP 2007183697A JP 2008020918 A5 JP2008020918 A5 JP 2008020918A5
- Authority
- JP
- Japan
- Prior art keywords
- lens
- silicone hydrogel
- hydrogel contact
- contact lens
- dry weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 229920001296 polysiloxane Polymers 0.000 claims description 196
- 239000000017 hydrogel Substances 0.000 claims description 190
- 239000000203 mixture Substances 0.000 claims description 59
- 239000000178 monomer Substances 0.000 claims description 37
- 238000000034 method Methods 0.000 claims description 34
- 239000000463 material Substances 0.000 claims description 30
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 29
- 239000000654 additive Substances 0.000 claims description 28
- 239000002243 precursor Substances 0.000 claims description 28
- 230000009257 reactivity Effects 0.000 claims description 17
- 229920005989 resin Polymers 0.000 claims description 17
- 239000011347 resin Substances 0.000 claims description 17
- 230000000996 additive effect Effects 0.000 claims description 7
- 229910052760 oxygen Inorganic materials 0.000 claims description 7
- 229920002554 vinyl polymer Polymers 0.000 claims description 7
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 6
- 239000001301 oxygen Substances 0.000 claims description 6
- 230000035699 permeability Effects 0.000 claims description 6
- 238000006116 polymerization reaction Methods 0.000 claims description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 5
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 3
- 230000008569 process Effects 0.000 claims description 3
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims description 3
- 230000004907 flux Effects 0.000 claims description 2
- 229920001577 copolymer Polymers 0.000 claims 2
- 238000000465 moulding Methods 0.000 claims 2
- 230000000379 polymerizing effect Effects 0.000 claims 2
- WGIMXKDCVCTHGW-UHFFFAOYSA-N 2-(2-hydroxyethoxy)ethyl dodecanoate Chemical compound CCCCCCCCCCCC(=O)OCCOCCO WGIMXKDCVCTHGW-UHFFFAOYSA-N 0.000 claims 1
- RFVNOJDQRGSOEL-UHFFFAOYSA-N 2-hydroxyethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCO RFVNOJDQRGSOEL-UHFFFAOYSA-N 0.000 claims 1
- 150000001412 amines Chemical class 0.000 claims 1
- 238000000605 extraction Methods 0.000 description 67
- 239000012632 extractable Substances 0.000 description 42
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 20
- 229910052710 silicon Inorganic materials 0.000 description 20
- 239000010703 silicon Substances 0.000 description 20
- 238000009472 formulation Methods 0.000 description 13
- 239000003623 enhancer Substances 0.000 description 11
- -1 polydimethylsiloxane Polymers 0.000 description 10
- 229920000642 polymer Polymers 0.000 description 8
- ZSZRUEAFVQITHH-UHFFFAOYSA-N 2-(2-methylprop-2-enoyloxy)ethyl 2-(trimethylazaniumyl)ethyl phosphate Chemical compound CC(=C)C(=O)OCCOP([O-])(=O)OCC[N+](C)(C)C ZSZRUEAFVQITHH-UHFFFAOYSA-N 0.000 description 6
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 6
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 6
- 239000003085 diluting agent Substances 0.000 description 6
- 239000000080 wetting agent Substances 0.000 description 6
- 239000004971 Cross linker Substances 0.000 description 5
- 239000002202 Polyethylene glycol Substances 0.000 description 5
- 238000001723 curing Methods 0.000 description 5
- 230000018044 dehydration Effects 0.000 description 5
- 238000006297 dehydration reaction Methods 0.000 description 5
- 125000000524 functional group Chemical group 0.000 description 5
- 229920001223 polyethylene glycol Polymers 0.000 description 5
- 238000004381 surface treatment Methods 0.000 description 5
- 239000003638 chemical reducing agent Substances 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 238000003754 machining Methods 0.000 description 3
- 239000002953 phosphate buffered saline Substances 0.000 description 3
- YHHSONZFOIEMCP-UHFFFAOYSA-O phosphocholine Chemical compound C[N+](C)(C)CCOP(O)(O)=O YHHSONZFOIEMCP-UHFFFAOYSA-O 0.000 description 3
- 229950004354 phosphorylcholine Drugs 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- LVLANIHJQRZTPY-UHFFFAOYSA-N vinyl carbamate Chemical compound NC(=O)OC=C LVLANIHJQRZTPY-UHFFFAOYSA-N 0.000 description 3
- VAYTZRYEBVHVLE-UHFFFAOYSA-N 1,3-dioxol-2-one Chemical compound O=C1OC=CO1 VAYTZRYEBVHVLE-UHFFFAOYSA-N 0.000 description 2
- QRIMLDXJAPZHJE-UHFFFAOYSA-N 2,3-dihydroxypropyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCC(O)CO QRIMLDXJAPZHJE-UHFFFAOYSA-N 0.000 description 2
- OMIGHNLMNHATMP-UHFFFAOYSA-N 2-hydroxyethyl prop-2-enoate Chemical compound OCCOC(=O)C=C OMIGHNLMNHATMP-UHFFFAOYSA-N 0.000 description 2
- IQAGXMNEUYBTLG-UHFFFAOYSA-N 5-hydroxy-2-methylpent-2-enamide Chemical compound NC(=O)C(C)=CCCO IQAGXMNEUYBTLG-UHFFFAOYSA-N 0.000 description 2
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical group NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical group CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- 239000007983 Tris buffer Substances 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 230000036571 hydration Effects 0.000 description 2
- 238000006703 hydration reaction Methods 0.000 description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- FQPSGWSUVKBHSU-UHFFFAOYSA-N methacrylamide Chemical group CC(=C)C(N)=O FQPSGWSUVKBHSU-UHFFFAOYSA-N 0.000 description 2
- 229940088644 n,n-dimethylacrylamide Drugs 0.000 description 2
- YLGYACDQVQQZSW-UHFFFAOYSA-N n,n-dimethylprop-2-enamide Chemical compound CN(C)C(=O)C=C YLGYACDQVQQZSW-UHFFFAOYSA-N 0.000 description 2
- 229910052757 nitrogen Inorganic materials 0.000 description 2
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 238000010186 staining Methods 0.000 description 2
- 230000003068 static effect Effects 0.000 description 2
- 125000005504 styryl group Chemical group 0.000 description 2
- 230000003746 surface roughness Effects 0.000 description 2
- SJHPCNCNNSSLPL-CSKARUKUSA-N (4e)-4-(ethoxymethylidene)-2-phenyl-1,3-oxazol-5-one Chemical compound O1C(=O)C(=C/OCC)\N=C1C1=CC=CC=C1 SJHPCNCNNSSLPL-CSKARUKUSA-N 0.000 description 1
- CYIGRWUIQAVBFG-UHFFFAOYSA-N 1,2-bis(2-ethenoxyethoxy)ethane Chemical compound C=COCCOCCOCCOC=C CYIGRWUIQAVBFG-UHFFFAOYSA-N 0.000 description 1
- KOMNUTZXSVSERR-UHFFFAOYSA-N 1,3,5-tris(prop-2-enyl)-1,3,5-triazinane-2,4,6-trione Chemical compound C=CCN1C(=O)N(CC=C)C(=O)N(CC=C)C1=O KOMNUTZXSVSERR-UHFFFAOYSA-N 0.000 description 1
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical group COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 1
- VFOZPUQEFHZHBT-UHFFFAOYSA-N 2-ethenylbenzoyl chloride Chemical compound ClC(=O)C1=CC=CC=C1C=C VFOZPUQEFHZHBT-UHFFFAOYSA-N 0.000 description 1
- KSPIIRRUVXRIRA-UHFFFAOYSA-M 2-hydroxyethyl-dimethyl-[(oxo-$l^{5}-phosphanylidyne)methyl]azanium;2-methylprop-2-enoate Chemical group CC(=C)C([O-])=O.OCC[N+](C)(C)C#P=O KSPIIRRUVXRIRA-UHFFFAOYSA-M 0.000 description 1
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 description 1
- BESKSSIEODQWBP-UHFFFAOYSA-N 3-tris(trimethylsilyloxy)silylpropyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C BESKSSIEODQWBP-UHFFFAOYSA-N 0.000 description 1
- 102220573536 C-C motif chemokine 5_T31A_mutation Human genes 0.000 description 1
- 208000003556 Dry Eye Syndromes Diseases 0.000 description 1
- 206010013774 Dry eye Diseases 0.000 description 1
- 206010015946 Eye irritation Diseases 0.000 description 1
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 description 1
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 description 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical group CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 description 1
- NSMPFGWDOGVQDR-UHFFFAOYSA-N N-carboxy-beta-alanine Chemical compound OC(=O)CCNC(O)=O NSMPFGWDOGVQDR-UHFFFAOYSA-N 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 102220529191 Receptor expression-enhancing protein 5_T31E_mutation Human genes 0.000 description 1
- RZKKLXUEULTOGP-UHFFFAOYSA-N [dimethyl(trimethylsilyloxy)silyl]methyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OC[Si](C)(C)O[Si](C)(C)C RZKKLXUEULTOGP-UHFFFAOYSA-N 0.000 description 1
- YPMNWQTVWVHXIQ-UHFFFAOYSA-N [methyl-bis(trimethylsilyloxy)silyl]methyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OC[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C YPMNWQTVWVHXIQ-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M acrylate group Chemical group C(C=C)(=O)[O-] NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 210000004087 cornea Anatomy 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 239000003431 cross linking reagent Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 125000004185 ester group Chemical group 0.000 description 1
- UYMKPFRHYYNDTL-UHFFFAOYSA-N ethenamine Chemical group NC=C UYMKPFRHYYNDTL-UHFFFAOYSA-N 0.000 description 1
- FFYWKOUKJFCBAM-UHFFFAOYSA-N ethenyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OC=C FFYWKOUKJFCBAM-UHFFFAOYSA-N 0.000 description 1
- BPFOYPDHLJUICH-UHFFFAOYSA-N ethenyl ethyl carbonate Chemical compound CCOC(=O)OC=C BPFOYPDHLJUICH-UHFFFAOYSA-N 0.000 description 1
- FXPHJTKVWZVEGA-UHFFFAOYSA-N ethenyl hydrogen carbonate Chemical compound OC(=O)OC=C FXPHJTKVWZVEGA-UHFFFAOYSA-N 0.000 description 1
- ILHMPZFVDISGNP-UHFFFAOYSA-N ethenyl n-[3-tris(trimethylsilyloxy)silylpropyl]carbamate Chemical compound C[Si](C)(C)O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)CCCNC(=O)OC=C ILHMPZFVDISGNP-UHFFFAOYSA-N 0.000 description 1
- KRAZQXAPJAYYJI-UHFFFAOYSA-N ethenyl trimethylsilylmethyl carbonate Chemical compound C[Si](C)(C)COC(=O)OC=C KRAZQXAPJAYYJI-UHFFFAOYSA-N 0.000 description 1
- STVZJERGLQHEKB-UHFFFAOYSA-N ethylene glycol dimethacrylate Chemical compound CC(=C)C(=O)OCCOC(=O)C(C)=C STVZJERGLQHEKB-UHFFFAOYSA-N 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 231100000013 eye irritation Toxicity 0.000 description 1
- 238000013007 heat curing Methods 0.000 description 1
- 150000004677 hydrates Chemical class 0.000 description 1
- 230000000887 hydrating effect Effects 0.000 description 1
- 238000010191 image analysis Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 125000005395 methacrylic acid group Chemical group 0.000 description 1
- DCUFMVPCXCSVNP-UHFFFAOYSA-N methacrylic anhydride Chemical compound CC(=C)C(=O)OC(=O)C(C)=C DCUFMVPCXCSVNP-UHFFFAOYSA-N 0.000 description 1
- VHRYZQNGTZXDNX-UHFFFAOYSA-N methacryloyl chloride Chemical compound CC(=C)C(Cl)=O VHRYZQNGTZXDNX-UHFFFAOYSA-N 0.000 description 1
- RBQRWNWVPQDTJJ-UHFFFAOYSA-N methacryloyloxyethyl isocyanate Chemical group CC(=C)C(=O)OCCN=C=O RBQRWNWVPQDTJJ-UHFFFAOYSA-N 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- GORGQKRVQGXVEB-UHFFFAOYSA-N n-ethenyl-n-ethylacetamide Chemical compound CCN(C=C)C(C)=O GORGQKRVQGXVEB-UHFFFAOYSA-N 0.000 description 1
- PNLUGRYDUHRLOF-UHFFFAOYSA-N n-ethenyl-n-methylacetamide Chemical compound C=CN(C)C(C)=O PNLUGRYDUHRLOF-UHFFFAOYSA-N 0.000 description 1
- ZQXSMRAEXCEDJD-UHFFFAOYSA-N n-ethenylformamide Chemical compound C=CNC=O ZQXSMRAEXCEDJD-UHFFFAOYSA-N 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 125000005375 organosiloxane group Chemical group 0.000 description 1
- 125000001181 organosilyl group Chemical group [SiH3]* 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- 229920000575 polymersome Polymers 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 150000003077 polyols Chemical class 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000011417 postcuring Methods 0.000 description 1
- 239000010453 quartz Substances 0.000 description 1
- 102200049243 rs121912470 Human genes 0.000 description 1
- 102200048773 rs2224391 Human genes 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 229920005573 silicon-containing polymer Polymers 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000009864 tensile test Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- HFMRLLVZHLGNAO-UHFFFAOYSA-N trimethylsilyloxysilicon Chemical compound C[Si](C)(C)O[Si] HFMRLLVZHLGNAO-UHFFFAOYSA-N 0.000 description 1
- 239000006097 ultraviolet radiation absorber Substances 0.000 description 1
- 229920001567 vinyl ester resin Polymers 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80491106P | 2006-06-15 | 2006-06-15 | |
| US88751307P | 2007-01-31 | 2007-01-31 | |
| US89460907P | 2007-03-13 | 2007-03-13 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014009742A Division JP5982684B2 (ja) | 2006-06-15 | 2014-01-22 | 湿潤性シリコーンヒドロゲルコンタクトレンズ及び関連組成物及び方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008020918A JP2008020918A (ja) | 2008-01-31 |
| JP2008020918A5 true JP2008020918A5 (https=) | 2013-01-10 |
Family
ID=39007968
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007183697A Pending JP2008020918A (ja) | 2006-06-15 | 2007-06-15 | 湿潤性シリコーンヒドロゲルコンタクトレンズ及び関連組成物及び方法 |
| JP2007183695A Expired - Fee Related JP5024702B2 (ja) | 2006-06-15 | 2007-06-15 | 湿潤性シリコーンヒドロゲルコンタクトレンズ及び関連組成物及び方法 |
| JP2007183696A Active JP5224090B2 (ja) | 2006-06-15 | 2007-06-15 | 湿潤性シリコーンヒドロゲルコンタクトレンズ及び関連組成物及び方法 |
| JP2014009742A Active JP5982684B2 (ja) | 2006-06-15 | 2014-01-22 | 湿潤性シリコーンヒドロゲルコンタクトレンズ及び関連組成物及び方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007183695A Expired - Fee Related JP5024702B2 (ja) | 2006-06-15 | 2007-06-15 | 湿潤性シリコーンヒドロゲルコンタクトレンズ及び関連組成物及び方法 |
| JP2007183696A Active JP5224090B2 (ja) | 2006-06-15 | 2007-06-15 | 湿潤性シリコーンヒドロゲルコンタクトレンズ及び関連組成物及び方法 |
| JP2014009742A Active JP5982684B2 (ja) | 2006-06-15 | 2014-01-22 | 湿潤性シリコーンヒドロゲルコンタクトレンズ及び関連組成物及び方法 |
Country Status (2)
| Country | Link |
|---|---|
| JP (4) | JP2008020918A (https=) |
| TW (4) | TWI429713B (https=) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009091733A2 (en) * | 2008-01-14 | 2009-07-23 | Coopervision International Holding Company, Lp | Polymerizable contact lens formulations and contact lenses obtained therefrom |
| SG175812A1 (en) * | 2009-10-01 | 2011-12-29 | Coopervision Int Holding Co Lp | Silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses |
| JP2013525842A (ja) * | 2010-04-23 | 2013-06-20 | ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッド | レンズ回転の改善方法 |
| EP2590810B9 (en) * | 2010-07-09 | 2023-11-01 | CooperVision International Limited | Ophthalmic lens molds with low levels of uv light transmittance, ophthalmic lenses molded therein, and related methods |
| US8480227B2 (en) * | 2010-07-30 | 2013-07-09 | Novartis Ag | Silicone hydrogel lenses with water-rich surfaces |
| MY166501A (en) | 2010-07-30 | 2018-06-27 | Coopervision Int Holding Co Lp | Ophthalmic lens molds, ophthalmic lenses molded therein, and related methods |
| HUE043683T2 (hu) * | 2011-02-28 | 2019-09-30 | Coopervision Int Holding Co Lp | Szilikon hidrogél kontaktlencsék elfogadható energiaveszteség-szintekkel |
| EP2681615B1 (en) * | 2011-02-28 | 2021-12-15 | CooperVision International Limited | Silicone hydrogel contact lenses and method of manufacturing the same |
| CN103827175B (zh) * | 2011-02-28 | 2016-08-10 | 库柏维景国际控股公司 | 硅酮水凝胶隐形眼镜 |
| KR101742351B1 (ko) * | 2011-02-28 | 2017-05-31 | 쿠퍼비젼 인터내셔날 홀딩 캄파니, 엘피 | 포스핀-함유 히드로겔 콘택트 렌즈 |
| MX353647B (es) * | 2011-02-28 | 2018-01-15 | Coopervision Int Holding Co Lp | Lentes de contacto de hidrogel de silicona. |
| JP5980626B2 (ja) * | 2011-08-31 | 2016-08-31 | 三洋化成工業株式会社 | 活性エネルギー線硬化性樹脂組成物 |
| US9156934B2 (en) | 2011-12-23 | 2015-10-13 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels comprising n-vinyl amides and hydroxyalkyl (meth)acrylates or (meth)acrylamides |
| US8937111B2 (en) | 2011-12-23 | 2015-01-20 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels comprising desirable water content and oxygen permeability |
| US9140825B2 (en) | 2011-12-23 | 2015-09-22 | Johnson & Johnson Vision Care, Inc. | Ionic silicone hydrogels |
| US9588258B2 (en) | 2011-12-23 | 2017-03-07 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels formed from zero diluent reactive mixtures |
| US8937110B2 (en) | 2011-12-23 | 2015-01-20 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels having a structure formed via controlled reaction kinetics |
| TWI496838B (zh) * | 2012-11-30 | 2015-08-21 | Pegavision Corp | 矽水膠組成物及以該組成物製備之矽水膠鏡片 |
| US9161598B2 (en) * | 2012-12-21 | 2015-10-20 | Coopervision International Holding Company, Lp | Ophthalmic devices for delivery of beneficial agents |
| KR101640725B1 (ko) * | 2013-04-30 | 2016-07-18 | 쿠퍼비젼 인터내셔날 홀딩 캄파니, 엘피 | 1급 아민-함유 실리콘 히드로겔 콘택트 렌즈, 및 관련 조성물 및 방법 |
| JP5452756B1 (ja) | 2013-07-02 | 2014-03-26 | Ｈｏｙａ株式会社 | 親水性表面を有するシリコーン含有共重合体成形品を作製する方法及び親水性表面を有するシリコーンハイドロゲルコンタクトレンズ |
| JP6329005B2 (ja) * | 2014-06-05 | 2018-05-23 | 株式会社メニコン | 眼用レンズ |
| TWI571670B (zh) * | 2015-01-09 | 2017-02-21 | Composite contact lenses | |
| KR101786302B1 (ko) * | 2016-03-03 | 2017-10-17 | (주)메디오스 | 청광차단 소프트 콘택트렌즈의 제조방법 및 이를 이용하여 제조된 소프트 콘택트렌즈 |
| WO2018069815A1 (en) * | 2016-10-11 | 2018-04-19 | Novartis Ag | Chain-extended polydimethylsiloxane vinylic crosslinkers and uses thereof |
| WO2018224975A1 (en) * | 2017-06-07 | 2018-12-13 | Novartis Ag | Silicone hydrogel contact lenses |
| EP4481478A3 (en) | 2017-06-07 | 2025-03-26 | Alcon Inc. | Silicone hydrogel contact lenses |
| JP6907845B2 (ja) * | 2017-09-13 | 2021-07-21 | 日油株式会社 | コンタクトレンズ用モノマー組成物、コンタクトレンズ用重合体及びその製造方法、並びにコンタクトレンズ及びその製造方法 |
| WO2019221838A1 (en) * | 2018-05-15 | 2019-11-21 | Bausch & Lomb Incorporated | Water extractable ophthalmic devices |
| EP3816206B1 (en) | 2018-06-27 | 2023-05-24 | Sumitomo Chemical Company Limited | Gel containing condensation product of reactive silicon compound |
| EP3818401B1 (en) * | 2018-07-03 | 2024-10-30 | Bausch & Lomb Incorporated | Water extractable ophthalmic devices |
| MY200843A (en) | 2018-09-14 | 2024-01-18 | Nof Corp | Monomer Composition for Contact Lens, Polymer Thereof, Contact Lens, and Production Method Thereof |
| KR102943093B1 (ko) | 2019-12-27 | 2026-03-23 | 니치유 가부시키가이샤 | 포스포릴콜린기 함유 폴리실록세인 모노머 |
| TWI779275B (zh) * | 2020-03-31 | 2022-10-01 | 望隼科技股份有限公司 | 防藍光隱形眼鏡、其組合物及製備方法 |
| US11822153B2 (en) * | 2020-09-28 | 2023-11-21 | Johnson & Johnson Vision Care, Inc. | Optical lens design for flattening a through-focus curve |
| CN116997846A (zh) | 2021-04-21 | 2023-11-03 | 日油株式会社 | 隐形眼镜用单体组合物、其聚合物、隐形眼镜及其制造方法 |
| JPWO2024143214A1 (https=) * | 2022-12-27 | 2024-07-04 | ||
| AU2024288300B2 (en) * | 2023-07-11 | 2026-04-23 | Coopervision International Limited | Contact lens formulation and contact lens |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4678838A (en) * | 1986-08-04 | 1987-07-07 | Ciba-Geigy Corporation | Particulate hydroperoxidized poly-N-vinyl lactam, its preparation and use thereof |
| CA2009668A1 (en) * | 1989-02-16 | 1990-08-16 | Ashok R. Thakrar | Colored contact lenses and method of making same |
| US5310779A (en) * | 1991-11-05 | 1994-05-10 | Bausch & Lomb Incorporated | UV curable crosslinking agents useful in copolymerization |
| US5760100B1 (en) * | 1994-09-06 | 2000-11-14 | Ciba Vision Corp | Extended wear ophthalmic lens |
| JPH10195324A (ja) * | 1997-01-16 | 1998-07-28 | Hoya Corp | 反応性黄色染料およびそれを含む眼用レンズ |
| US6367929B1 (en) * | 1998-03-02 | 2002-04-09 | Johnson & Johnson Vision Care, Inc. | Hydrogel with internal wetting agent |
| US7052131B2 (en) * | 2001-09-10 | 2006-05-30 | J&J Vision Care, Inc. | Biomedical devices containing internal wetting agents |
| US6359024B2 (en) * | 1998-05-15 | 2002-03-19 | Bausch & Lomb Incorporated | Method for polymerizing contact lenses |
| HK1047117B (en) * | 1999-10-07 | 2007-01-19 | 庄臣及庄臣视力保护公司 | Soft contact lenses |
| DE60042841D1 (de) * | 1999-12-16 | 2009-10-08 | Asahikasei Aime Co Ltd | Zum tragen über lange zeiträume geeignete weiche kontaktlinsen |
| JP2001201723A (ja) * | 2000-01-18 | 2001-07-27 | Asahi Kasei Aimii Kk | 連続装用ソフトコンタクトレンズ |
| JP4438162B2 (ja) * | 2000-02-24 | 2010-03-24 | 東レ株式会社 | 眼用レンズ用ポリマーの製造法および眼用レンズ |
| JP4441998B2 (ja) * | 2000-07-14 | 2010-03-31 | 日油株式会社 | コンタクトレンズ材料、コンタクトレンズ及びその製造方法 |
| US7879267B2 (en) * | 2001-08-02 | 2011-02-01 | J&J Vision Care, Inc. | Method for coating articles by mold transfer |
| JP2004085655A (ja) * | 2002-08-23 | 2004-03-18 | Asahi Kasei Aimii Kk | 耐汚染性の含水ソフトコンタクトレンズ |
| WO2004063795A1 (ja) * | 2003-01-10 | 2004-07-29 | Menicon Co., Ltd. | 安全性の高いシリコーン含有眼用レンズ材料およびその製造方法 |
| US20060063852A1 (en) * | 2004-08-27 | 2006-03-23 | Asahikasei Aime Co. Ltd. | Silicone hydrogel contact lens |
| US7249848B2 (en) * | 2004-09-30 | 2007-07-31 | Johnson & Johnson Vision Care, Inc. | Wettable hydrogels comprising reactive, hydrophilic, polymeric internal wetting agents |
| JP2007183697A (ja) * | 2005-12-31 | 2007-07-19 | Mitsuyo Nakagami | 携帯型カルテ表示装置、携帯型カルテ表示プログラム及びコンピュータ読み取り可能な記録媒体 |
-
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- 2007-06-15 JP JP2007183697A patent/JP2008020918A/ja active Pending
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