JP2007538025A - エストラジオールプロドラッグ - Google Patents
エストラジオールプロドラッグ Download PDFInfo
- Publication number
- JP2007538025A JP2007538025A JP2007517046A JP2007517046A JP2007538025A JP 2007538025 A JP2007538025 A JP 2007538025A JP 2007517046 A JP2007517046 A JP 2007517046A JP 2007517046 A JP2007517046 A JP 2007517046A JP 2007538025 A JP2007538025 A JP 2007538025A
- Authority
- JP
- Japan
- Prior art keywords
- group
- trien
- sulfamoylbenzoate
- hydroxyestradi
- methoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004025966A DE102004025966A1 (de) | 2004-05-21 | 2004-05-21 | Estradiol-Prodrugs |
PCT/EP2005/005254 WO2005113574A1 (de) | 2004-05-21 | 2005-05-10 | Aminosulfonyl- oder aminosulfonylamino-substituierte phenyl-ester als estradiol-prodrugs |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2007538025A true JP2007538025A (ja) | 2007-12-27 |
JP2007538025A5 JP2007538025A5 (de) | 2008-06-26 |
Family
ID=34969196
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2007517046A Pending JP2007538025A (ja) | 2004-05-21 | 2005-05-10 | エストラジオールプロドラッグ |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1747230A1 (de) |
JP (1) | JP2007538025A (de) |
AR (1) | AR050335A1 (de) |
DE (1) | DE102004025966A1 (de) |
GT (1) | GT200500121A (de) |
PA (1) | PA8633701A1 (de) |
PE (1) | PE20060359A1 (de) |
SV (1) | SV2006002121A (de) |
TW (1) | TW200613315A (de) |
UY (1) | UY28909A1 (de) |
WO (1) | WO2005113574A1 (de) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007538027A (ja) * | 2004-05-21 | 2007-12-27 | バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト | エストリオール及びエステトロールプロドラッグ類 |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10027887A1 (de) | 2000-05-31 | 2001-12-13 | Jenapharm Gmbh | Verbindungen mit einer Sulfonamidgruppe und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen |
US7534780B2 (en) | 2004-05-21 | 2009-05-19 | Bayer Schering Pharma Aktiengesellschaft | Estradiol prodrugs |
DE102005057224A1 (de) * | 2005-11-29 | 2007-05-31 | Bayer Schering Pharma Ag | Prodrugs ERß-selektiver Substanzen, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen |
DE102005057225A1 (de) * | 2005-11-29 | 2007-05-31 | Bayer Schering Pharma Ag | Prodrugs ERß-selektiver Substanzen, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen |
DE102005057408A1 (de) * | 2005-11-30 | 2007-05-31 | Bayer Schering Pharma Ag | Sulfamoylsulfonat-Prodrugs |
AU2014287049B2 (en) * | 2013-07-11 | 2019-09-26 | Evestra, Inc. | Pro-drug forming compounds |
CN115368427B (zh) * | 2022-08-17 | 2024-02-13 | 南宁师范大学 | 雌二醇硒氰酸酯类化合物及其制备方法与应用 |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB915129A (en) * | 1958-08-04 | 1963-01-09 | Roussel Uclaf | New steroid compounds and a process for their preparation |
GB1272688A (en) * | 1968-12-31 | 1972-05-03 | Rech Chimiques Et Ind Mar Lab | Sulphamido-steroids and the preparation thereof |
WO2001081364A1 (fr) * | 2000-04-24 | 2001-11-01 | Kyowa Hakko Kogyo Co., Ltd. | Derives d'estra-1,3,5(10)-triene |
WO2002000679A2 (en) * | 2000-06-28 | 2002-01-03 | Novartis Ag | 9.alpha.-chloro-6.alpha.-fluoro-17.alpha.-hydroxy-16-methyl-17-beta-methoxycarbonyl-androst-1,4-dienes esterified in position 17.alpha. by a cyclic acyl group |
JP2003534386A (ja) * | 2000-05-31 | 2003-11-18 | シエーリング アクチエンゲゼルシャフト | スルホンアミド基を有する化合物及びこれらの化合物を含む医薬組成物 |
WO2005005451A1 (en) * | 2003-07-11 | 2005-01-20 | Glaxo Group Limited | Specific glucocorticosteroid compound having anti- inflammatory activity |
WO2005047303A2 (en) * | 2003-11-12 | 2005-05-26 | Solvay Pharmaceuticals Gmbh | NOVEL 17β HYDROXYSTEROID DEHYDROGENASE TYPE I INHIBITORS |
JP2007538027A (ja) * | 2004-05-21 | 2007-12-27 | バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト | エストリオール及びエステトロールプロドラッグ類 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5001234A (en) * | 1987-04-16 | 1991-03-19 | The Upjohn Company | Cyclic hydrocarbons with an aminoalkyl sidechain |
US5571933A (en) * | 1994-11-17 | 1996-11-05 | Duquesne University Of The Holy Ghost | Derivatives of estra 1,3,5(10)triene-17-one, 3-amino compounds and their use |
DE19712488A1 (de) * | 1997-03-25 | 1998-10-01 | Knoell Hans Forschung Ev | Steroidsulfamate, Verfahren zu ihrer Herstellung und Anwendung derselben |
-
2004
- 2004-05-21 DE DE102004025966A patent/DE102004025966A1/de not_active Withdrawn
-
2005
- 2005-05-10 JP JP2007517046A patent/JP2007538025A/ja active Pending
- 2005-05-10 EP EP05747458A patent/EP1747230A1/de not_active Withdrawn
- 2005-05-10 WO PCT/EP2005/005254 patent/WO2005113574A1/de active Application Filing
- 2005-05-19 UY UY28909A patent/UY28909A1/es not_active Application Discontinuation
- 2005-05-20 TW TW094116503A patent/TW200613315A/zh unknown
- 2005-05-20 PE PE2005000557A patent/PE20060359A1/es not_active Application Discontinuation
- 2005-05-20 AR ARP050102083A patent/AR050335A1/es unknown
- 2005-05-20 PA PA20058633701A patent/PA8633701A1/es unknown
- 2005-05-20 GT GT200500121A patent/GT200500121A/es unknown
- 2005-05-23 SV SV2005002121A patent/SV2006002121A/es not_active Application Discontinuation
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB915129A (en) * | 1958-08-04 | 1963-01-09 | Roussel Uclaf | New steroid compounds and a process for their preparation |
GB1272688A (en) * | 1968-12-31 | 1972-05-03 | Rech Chimiques Et Ind Mar Lab | Sulphamido-steroids and the preparation thereof |
WO2001081364A1 (fr) * | 2000-04-24 | 2001-11-01 | Kyowa Hakko Kogyo Co., Ltd. | Derives d'estra-1,3,5(10)-triene |
JP2003534386A (ja) * | 2000-05-31 | 2003-11-18 | シエーリング アクチエンゲゼルシャフト | スルホンアミド基を有する化合物及びこれらの化合物を含む医薬組成物 |
WO2002000679A2 (en) * | 2000-06-28 | 2002-01-03 | Novartis Ag | 9.alpha.-chloro-6.alpha.-fluoro-17.alpha.-hydroxy-16-methyl-17-beta-methoxycarbonyl-androst-1,4-dienes esterified in position 17.alpha. by a cyclic acyl group |
WO2005005451A1 (en) * | 2003-07-11 | 2005-01-20 | Glaxo Group Limited | Specific glucocorticosteroid compound having anti- inflammatory activity |
WO2005047303A2 (en) * | 2003-11-12 | 2005-05-26 | Solvay Pharmaceuticals Gmbh | NOVEL 17β HYDROXYSTEROID DEHYDROGENASE TYPE I INHIBITORS |
JP2007538027A (ja) * | 2004-05-21 | 2007-12-27 | バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト | エストリオール及びエステトロールプロドラッグ類 |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007538027A (ja) * | 2004-05-21 | 2007-12-27 | バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト | エストリオール及びエステトロールプロドラッグ類 |
Also Published As
Publication number | Publication date |
---|---|
TW200613315A (en) | 2006-05-01 |
PE20060359A1 (es) | 2006-05-25 |
AR050335A1 (es) | 2006-10-18 |
WO2005113574A1 (de) | 2005-12-01 |
UY28909A1 (es) | 2005-12-30 |
SV2006002121A (es) | 2006-02-15 |
PA8633701A1 (es) | 2006-07-03 |
EP1747230A1 (de) | 2007-01-31 |
GT200500121A (es) | 2006-01-30 |
DE102004025966A1 (de) | 2005-12-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20080509 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20080509 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20110607 |
|
A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20111101 |