JP2007533735A5 - - Google Patents
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- Publication number
- JP2007533735A5 JP2007533735A5 JP2007509422A JP2007509422A JP2007533735A5 JP 2007533735 A5 JP2007533735 A5 JP 2007533735A5 JP 2007509422 A JP2007509422 A JP 2007509422A JP 2007509422 A JP2007509422 A JP 2007509422A JP 2007533735 A5 JP2007533735 A5 JP 2007533735A5
- Authority
- JP
- Japan
- Prior art keywords
- phenylimidazolidine
- enoyl
- methylsulfonyl
- piperidin
- piperidinyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- BKBCQSQQVKMAHL-JJDZQTOISA-N (4r,5s)-1,5-dimethyl-3-[(e)-3-(1-methylsulfonylpiperidin-4-yl)prop-2-enoyl]-4-phenylimidazolidin-2-one Chemical compound N1([C@@H]([C@@H](N(C1=O)C)C)C=1C=CC=CC=1)C(=O)\C=C\C1CCN(S(C)(=O)=O)CC1 BKBCQSQQVKMAHL-JJDZQTOISA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 125000004433 nitrogen atom Chemical group N* 0.000 description 1
- 125000003386 piperidinyl group Chemical group 0.000 description 1
- 125000000719 pyrrolidinyl group Chemical group 0.000 description 1
- 125000006413 ring segment Chemical group 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0401057A SE0401057D0 (sv) | 2004-04-23 | 2004-04-23 | Chemical Compounds |
| SE0500057A SE0500057D0 (sv) | 2005-01-10 | 2005-01-10 | Chemical compounds |
| PCT/SE2005/000574 WO2005101989A2 (en) | 2004-04-23 | 2005-04-20 | Piperidine derivatives as modulators of chemokine receptor ccr5 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007533735A JP2007533735A (ja) | 2007-11-22 |
| JP2007533735A5 true JP2007533735A5 (https=) | 2008-06-05 |
Family
ID=35197429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007509422A Pending JP2007533735A (ja) | 2004-04-23 | 2005-04-20 | ケモカイン受容体ｃｃｒ５のモジュレーターとしてのピペリジン誘導体 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US7615555B2 (https=) |
| EP (1) | EP1742934A2 (https=) |
| JP (1) | JP2007533735A (https=) |
| KR (1) | KR20070007345A (https=) |
| AR (1) | AR048834A1 (https=) |
| AU (1) | AU2005235169B2 (https=) |
| BR (1) | BRPI0510126A (https=) |
| CA (1) | CA2562417A1 (https=) |
| IL (1) | IL178650A0 (https=) |
| MX (1) | MXPA06012045A (https=) |
| NO (1) | NO20065319L (https=) |
| RU (1) | RU2368608C2 (https=) |
| SA (1) | SA05260099B1 (https=) |
| TW (1) | TW200610761A (https=) |
| UY (1) | UY28870A1 (https=) |
| WO (1) | WO2005101989A2 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602007007497D1 (de) | 2006-09-18 | 2010-08-12 | Hoffmann La Roche | Octahydropyrroloä3,4-cüpyrrolderivate und ihre verwendung als antivirale mittel |
| TW200831093A (en) * | 2006-12-11 | 2008-08-01 | Astrazeneca Ab | Chemical compound |
| TW200831483A (en) * | 2006-12-11 | 2008-08-01 | Astrazeneca Ab | Chemical compound |
| AU2007334519A1 (en) | 2006-12-14 | 2008-06-26 | Merck Sharp & Dohme Corp. | Acyl bipiperidinyl compounds, compositions containing such compounds and methods of treatment |
| EP2121679B1 (de) * | 2007-02-23 | 2015-04-15 | K.H.S. Pharma Holding Gmbh | Verfahren zur herstellung von azoniaspironortropinestern |
| US7977358B2 (en) | 2007-07-26 | 2011-07-12 | Hoffmann-La Roche Inc. | Pyrazol derivatives |
| MY157597A (en) | 2008-04-11 | 2016-06-30 | Janssen Pharmaceutica Nv | Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene a4 hydrolase |
| US8217060B2 (en) | 2009-05-15 | 2012-07-10 | Janssen Pharmaceutica, Nv | Benzimidazole derivatives useful as TRP M8 receptor modulators |
| WO2011011652A1 (en) | 2009-07-24 | 2011-01-27 | Glaxosmithkline Llc | Therapeutic compounds |
| CN102241664B (zh) * | 2010-05-13 | 2014-11-12 | 上海医药工业研究院 | 芳烷二胺类衍生物及其作为抗抑郁症药物的应用 |
| KR20130113948A (ko) | 2010-05-17 | 2013-10-16 | 어레이 바이오파마 인크. | Gpr119 조절제로서의 피페리디닐-치환된 락탐류 |
| WO2013074641A1 (en) * | 2011-11-16 | 2013-05-23 | Array Biopharma Inc. | Piperidinyl- substituted cyclic ureas as gpr119 modulators |
| JP6303250B2 (ja) | 2012-12-21 | 2018-04-04 | 石原産業株式会社 | 有害生物防除剤 |
| WO2014102594A2 (en) | 2012-12-27 | 2014-07-03 | Purdue Pharma L.P. | Substituted benzimidazole-type piperidine compounds and uses thereof |
| US10556899B2 (en) * | 2018-02-09 | 2020-02-11 | Sci Pharmtech, Inc. | Method for preparing Maraviroc |
| WO2025064788A2 (en) * | 2023-09-20 | 2025-03-27 | Cidara Therapeutics, Inc. | Ccr5 conjugates and uses thereof |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE912759A1 (en) | 1990-08-06 | 1992-02-12 | Smith Kline French Lab | Compounds |
| CA2296314A1 (en) * | 1997-07-25 | 1999-02-04 | Merck & Co., Inc. | Cyclic amine modulators of chemokine receptor activity |
| IL125658A0 (en) | 1997-08-18 | 1999-04-11 | Hoffmann La Roche | Ccr-3 receptor antagonists |
| AR013669A1 (es) * | 1997-10-07 | 2001-01-10 | Smithkline Beecham Corp | Compuestos y metodos |
| SK285729B6 (sk) * | 1997-11-18 | 2007-07-06 | Teijin Pharma Limited | Zlúčenina derivátov cyklických amínov a jej použitie |
| JP2002501898A (ja) | 1998-02-02 | 2002-01-22 | メルク エンド カムパニー インコーポレーテッド | ケモカイン受容体活性の環状アミン調節剤 |
| US6288083B1 (en) | 1998-09-04 | 2001-09-11 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US7217714B1 (en) * | 1998-12-23 | 2007-05-15 | Agouron Pharmaceuticals, Inc. | CCR5 modulators |
| EP1013276A1 (en) * | 1998-12-23 | 2000-06-28 | Pfizer Inc. | Aminoazacycloalkanes as CCR5 modulators |
| PE20001420A1 (es) * | 1998-12-23 | 2000-12-18 | Pfizer | Moduladores de ccr5 |
| SE9902987D0 (sv) * | 1999-08-24 | 1999-08-24 | Astra Pharma Prod | Novel compounds |
| CO5300399A1 (es) * | 2000-02-25 | 2003-07-31 | Astrazeneca Ab | Heterocicliocs que contienen nitrogeno, proceso para su preparacion y composiciones farmaceuticas que los contienen |
| GB0005642D0 (en) * | 2000-03-10 | 2000-05-03 | Astrazeneca Uk Ltd | Chemical compounds |
| GB0011838D0 (en) * | 2000-05-17 | 2000-07-05 | Astrazeneca Ab | Chemical compounds |
| CN100355753C (zh) * | 2000-05-26 | 2007-12-19 | 辉瑞大药厂 | 用于制备具有治疗作用的莨菪烷衍生物的中间体 |
| SE0103818D0 (sv) | 2001-11-15 | 2001-11-15 | Astrazeneca Ab | Chemical compounds |
| US6855724B2 (en) * | 2002-04-08 | 2005-02-15 | Agouron Pharmaceuticals, Inc. | Tropane derivatives useful in therapy |
| EP1352672A3 (en) * | 2002-04-08 | 2004-01-07 | Acrostak Corp. | PTCA and/or PTA balloon |
| US7645771B2 (en) | 2002-12-13 | 2010-01-12 | Smithkline Beecham Corp. | CCR5 antagonists as therapeutic agents |
| AR042628A1 (es) | 2002-12-20 | 2005-06-29 | Astrazeneca Ab | Derivados de piperidina como moduladores del receptor ccr5 |
| SE0203820D0 (sv) | 2002-12-20 | 2002-12-20 | Astrazeneca Ab | chemical compounds |
| SE0203828D0 (sv) * | 2002-12-20 | 2002-12-20 | Astrazeneca Ab | Chemical compounds |
| SE0401657D0 (sv) | 2004-06-24 | 2004-06-24 | Astrazeneca Ab | Chemical compounds |
| SE0401656D0 (sv) | 2004-06-24 | 2004-06-24 | Astrazeneca Ab | Chemical compounds |
| TW200831483A (en) | 2006-12-11 | 2008-08-01 | Astrazeneca Ab | Chemical compound |
| TW200831093A (en) | 2006-12-11 | 2008-08-01 | Astrazeneca Ab | Chemical compound |
-
2005
- 2005-04-11 TW TW094111402A patent/TW200610761A/zh unknown
- 2005-04-20 SA SA5260099A patent/SA05260099B1/ar unknown
- 2005-04-20 MX MXPA06012045A patent/MXPA06012045A/es active IP Right Grant
- 2005-04-20 JP JP2007509422A patent/JP2007533735A/ja active Pending
- 2005-04-20 WO PCT/SE2005/000574 patent/WO2005101989A2/en not_active Ceased
- 2005-04-20 KR KR1020067021878A patent/KR20070007345A/ko not_active Ceased
- 2005-04-20 EP EP05734934A patent/EP1742934A2/en not_active Withdrawn
- 2005-04-20 RU RU2006138663/04A patent/RU2368608C2/ru not_active IP Right Cessation
- 2005-04-20 BR BRPI0510126-3A patent/BRPI0510126A/pt not_active IP Right Cessation
- 2005-04-20 CA CA002562417A patent/CA2562417A1/en not_active Abandoned
- 2005-04-20 US US11/587,330 patent/US7615555B2/en not_active Expired - Fee Related
- 2005-04-20 AU AU2005235169A patent/AU2005235169B2/en not_active Ceased
- 2005-04-22 AR ARP050101605A patent/AR048834A1/es unknown
- 2005-04-22 UY UY28870A patent/UY28870A1/es unknown
-
2006
- 2006-10-16 IL IL178650A patent/IL178650A0/en unknown
- 2006-11-20 NO NO20065319A patent/NO20065319L/no not_active Application Discontinuation
-
2009
- 2009-09-18 US US12/562,651 patent/US20100010007A1/en not_active Abandoned
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