JP2007532649A5 - - Google Patents
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- Publication number
- JP2007532649A5 JP2007532649A5 JP2007508407A JP2007508407A JP2007532649A5 JP 2007532649 A5 JP2007532649 A5 JP 2007532649A5 JP 2007508407 A JP2007508407 A JP 2007508407A JP 2007508407 A JP2007508407 A JP 2007508407A JP 2007532649 A5 JP2007532649 A5 JP 2007532649A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl group
- compound
- medicament
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56264304P | 2004-04-15 | 2004-04-15 | |
| PCT/US2005/012028 WO2005108378A2 (en) | 2004-04-15 | 2005-04-12 | Use of (4-alkylpiperazinyl) (phenyl) methanones in the treatment of alzheimer’s disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007532649A JP2007532649A (ja) | 2007-11-15 |
| JP2007532649A5 true JP2007532649A5 (https=) | 2008-05-29 |
Family
ID=35058789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007508407A Pending JP2007532649A (ja) | 2004-04-15 | 2005-04-12 | （４−アルキルピペラジニル）（フェニル）メタノン |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20090197891A1 (https=) |
| EP (1) | EP1755605A2 (https=) |
| JP (1) | JP2007532649A (https=) |
| CN (1) | CN101022806A (https=) |
| AU (1) | AU2005240991A1 (https=) |
| CA (1) | CA2564068A1 (https=) |
| WO (1) | WO2005108378A2 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| RU2432362C2 (ru) | 2005-11-30 | 2011-10-27 | Эбботт Лэборетриз | Моноклональные антитела и их применения |
| PL2289909T3 (pl) | 2005-11-30 | 2015-04-30 | Abbvie Inc | Sposób przeszukiwania, proces oczyszczania niedyfundujących oligomerów Abeta, selektywne przeciwciała przeciw niedyfundującym oligomerom Abeta i sposób wytwarzania tych przeciwciał |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| EP2124952A2 (en) | 2007-02-27 | 2009-12-02 | Abbott GmbH & Co. KG | Method for the treatment of amyloidoses |
| ES2684475T3 (es) | 2010-04-15 | 2018-10-03 | Abbvie Inc. | Proteínas que se unen a beta amiloide |
| CN103298833B (zh) | 2010-08-14 | 2015-12-16 | Abbvie公司 | β淀粉样蛋白结合蛋白 |
| EP4092013A1 (en) | 2017-06-20 | 2022-11-23 | Imbria Pharmaceuticals, Inc. | Compositions and methods for increasing efficiency of cardiac metabolism |
| CN108329282B (zh) * | 2018-01-16 | 2022-01-07 | 新乡医学院 | 一种苯基哌嗪类衍生物及其制备方法和应用 |
| WO2020081361A1 (en) | 2018-10-17 | 2020-04-23 | Imbria Pharmaceuticals, Inc. | Methods of treating rheumatic diseases using trimetazidine-based compounds |
| WO2020243120A1 (en) | 2019-05-31 | 2020-12-03 | Imbria Pharmaceuticals, Inc. | Methods of treating fibrosis using compounds that promote glucose oxidation |
| US11780811B2 (en) | 2020-06-30 | 2023-10-10 | Imbria Pharmaceuticals, Inc. | Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
| US11530184B2 (en) | 2020-06-30 | 2022-12-20 | Imbria Pharmaceuticals, Inc. | Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
| US11883396B2 (en) | 2021-05-03 | 2024-01-30 | Imbria Pharmaceuticals, Inc. | Methods of treating kidney conditions using modified forms of trimetazidine |
| WO2022246115A1 (en) * | 2021-05-19 | 2022-11-24 | Cornell University | Apt1 and apt2 inhibitors and uses thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2304155A1 (de) * | 1973-01-29 | 1974-08-01 | Ichthyol Ges Cordes Hermanni & | N-acylierte substituierte piperazinbzw. homopiperazinderivate, sowie verfahren zu ihrer herstellung |
| US5693804A (en) * | 1994-11-17 | 1997-12-02 | Molecular Geriatrics Corporation | Substituted 1-aryl-3-piperazin-1'-yl propanones |
| DE19934433A1 (de) * | 1999-07-22 | 2001-01-25 | Merck Patent Gmbh | N-(Indolcarbonyl-)piperazinderivate |
| US20040034019A1 (en) * | 2002-08-08 | 2004-02-19 | Ronald Tomlinson | Piperazine and piperidine derivatives |
| GB0224084D0 (en) * | 2002-10-16 | 2002-11-27 | Glaxo Group Ltd | Novel compounds |
| EP1628649A4 (en) * | 2003-06-02 | 2010-06-02 | Samaritan Pharmaceuticals Inc | NEUROPROTECTIVE BENZOATE AND BENZAMIDE COMPOUNDS |
-
2005
- 2005-04-12 CN CNA2005800194203A patent/CN101022806A/zh active Pending
- 2005-04-12 JP JP2007508407A patent/JP2007532649A/ja active Pending
- 2005-04-12 US US10/599,952 patent/US20090197891A1/en not_active Abandoned
- 2005-04-12 AU AU2005240991A patent/AU2005240991A1/en not_active Abandoned
- 2005-04-12 EP EP05776434A patent/EP1755605A2/en not_active Withdrawn
- 2005-04-12 CA CA002564068A patent/CA2564068A1/en not_active Abandoned
- 2005-04-12 WO PCT/US2005/012028 patent/WO2005108378A2/en not_active Ceased
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