JP2007530580A5 - - Google Patents
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- Publication number
- JP2007530580A5 JP2007530580A5 JP2007505191A JP2007505191A JP2007530580A5 JP 2007530580 A5 JP2007530580 A5 JP 2007530580A5 JP 2007505191 A JP2007505191 A JP 2007505191A JP 2007505191 A JP2007505191 A JP 2007505191A JP 2007530580 A5 JP2007530580 A5 JP 2007530580A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pharmaceutical composition
- medicament
- inflammatory
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55692704P | 2004-03-26 | 2004-03-26 | |
| PCT/US2005/009899 WO2005097780A1 (en) | 2004-03-26 | 2005-03-24 | [4-(5-aminomethyl-2-fluoro-phenyl)-piperidin-1-yl]-(4-bromo-3-methyl-5-propoxy-thiophen-2-yl)-methanone hydrochloride as an inhibitor of mast cell tryptase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007530580A JP2007530580A (ja) | 2007-11-01 |
| JP2007530580A5 true JP2007530580A5 (https=) | 2008-05-08 |
Family
ID=34964263
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007505191A Abandoned JP2007530580A (ja) | 2004-03-26 | 2005-03-24 | 肥満細胞トリプターゼインヒビターとしての［４−（５−アミノメチル−２−フルオロ−フェニル）−ピペリジン−１−イル］−（４−ブロモ−３−メチル−５−プロポキシ−チオフェン−２−イル）−メタノンヒドロクロリド |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US20070142435A1 (https=) |
| EP (1) | EP1737848A1 (https=) |
| JP (1) | JP2007530580A (https=) |
| KR (1) | KR20060130682A (https=) |
| CN (1) | CN1956978A (https=) |
| AR (1) | AR048336A1 (https=) |
| AU (1) | AU2005230934A1 (https=) |
| BR (1) | BRPI0509245A (https=) |
| CA (1) | CA2560649A1 (https=) |
| CR (1) | CR8603A (https=) |
| DO (1) | DOP2005000039A (https=) |
| EC (1) | ECSP066878A (https=) |
| IL (1) | IL178031A0 (https=) |
| MA (1) | MA28547B1 (https=) |
| MX (1) | MXPA06010610A (https=) |
| NO (1) | NO20064811L (https=) |
| PA (1) | PA8627601A1 (https=) |
| PE (1) | PE20060084A1 (https=) |
| RU (1) | RU2330034C1 (https=) |
| TN (1) | TNSN06278A1 (https=) |
| TW (1) | TW200602035A (https=) |
| UA (1) | UA83738C2 (https=) |
| UY (1) | UY28821A1 (https=) |
| WO (1) | WO2005097780A1 (https=) |
| ZA (1) | ZA200607752B (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20071148A1 (es) * | 2006-03-29 | 2007-12-10 | Sanofi Aventis | Mejoras en la preparacion de intermedios que conducen a hidrocloruro de [4-(5-aminometil-2-fluoro-fenil)-piperidin-1-il]-(4-bromo-3-metil-5-propoxi-tiofen-2-il)-metanona |
| AR065616A1 (es) * | 2007-03-07 | 2009-06-17 | Sanofi Aventis | Sintesis regioselectiva de ullmann de acido 4- bromo-3- metil-5- propoxi- tiofeno-2- carboxilico |
| WO2008115912A1 (en) * | 2007-03-21 | 2008-09-25 | Sanofi-Aventis | Regio-specific synthesis of 4-bromo-3-methyl-5-propoxy-thiophene-2-carboxylic acid |
| AR065859A1 (es) * | 2007-03-29 | 2009-07-08 | Sanofi Aventis | Ester de 2,5-dioxo-pirrolidin-1-ilo de acido 4-bromo-3-metil-5-propoxitiofen-2- carboxilico ,su sintesis regioespecifica y un intermedio del mismo |
| AR065858A1 (es) * | 2007-03-29 | 2009-07-08 | Sanofi Aventis | Metodo para preparar el inhibidor de triptasa [ 4-(5-aminoetil-2-fluoro-fenil)-piperidin-1-il]-(4-bromo-3-metil-5-propoxi-tiofen-2-il)-metanona. |
| ES2469824T3 (es) * | 2007-11-21 | 2014-06-20 | Janssen Pharmaceutica N.V. | Espiropiperidinas para su uso como inhibidores de la triptasa |
| NZ587119A (en) * | 2008-01-24 | 2013-01-25 | Soligenix Inc | Use of beclomethasone dipropionate in the treatment of an interstitial lung disease |
| CN102149705B (zh) * | 2008-08-22 | 2013-08-07 | 赛诺菲-安万特 | 作为肥大细胞类胰蛋白酶抑制剂的[4-(5-氨基甲基-2-氟苯基)-哌啶-1-基]-[7-氟-1-(2-甲氧基乙基)-4-三氟甲氧基-1h-吲哚-3-基]-甲酮 |
| TW201034675A (en) | 2008-12-18 | 2010-10-01 | Sanofi Aventis | Method for treating macular degeneration |
| FR2955324A1 (fr) * | 2010-01-15 | 2011-07-22 | Sanofi Aventis | [4-(5-aminomethyl-phenyl)-piperidin-1-yl]-1h-indol-3-yl]-methanones disubstituees |
| EP2483243B1 (en) | 2009-09-24 | 2015-03-18 | Sanofi-Aventis U.S. LLC | Synthesis of (4-fluoro-3-piperidin-4-yl-benzyl)-carbamic acid tert-butyl ester and intermediates thereof |
| CA2784894A1 (en) * | 2009-12-23 | 2011-06-30 | Sanofi | Indolyl-piperidinyl benzylamines as beta-tryptase inhibitors |
| EP2516428A1 (en) * | 2009-12-23 | 2012-10-31 | Sanofi | Tropinone benzylamines as beta-tryptase inhibitors |
| AU2010333892A1 (en) * | 2009-12-23 | 2012-07-19 | Sanofi | Treatment for inflammatory bowel disease |
| AU2011220909A1 (en) * | 2010-02-24 | 2012-09-13 | Sanofi | Treatment of dermatological allergic conditions |
| PL2763979T3 (pl) | 2011-10-07 | 2019-06-28 | Takeda Pharmaceutical Company Limited | Związki 1-arylokarbonyl-4-oksy-piperydynowe użyteczne do leczenia chorób neurodegeneracyjnych |
| PE20191548A1 (es) * | 2017-02-10 | 2019-10-24 | Genentech Inc | Anticuerpos contra triptasa, composiciones de estos y usos de estos |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0012362D0 (en) * | 2000-05-22 | 2000-07-12 | Aventis Pharma Ltd | Chemical compounds |
| DZ3347A1 (fr) * | 2000-05-22 | 2001-11-29 | Aventis Pharma Inc | Dérivés d'arylméthylamine pour leur utilisation comme inhibiteurs de la tryptase |
-
2005
- 2005-03-21 DO DO2005000039A patent/DOP2005000039A/es unknown
- 2005-03-22 PE PE2005000325A patent/PE20060084A1/es not_active Application Discontinuation
- 2005-03-23 UY UY28821A patent/UY28821A1/es unknown
- 2005-03-23 AR ARP050101170A patent/AR048336A1/es not_active Application Discontinuation
- 2005-03-24 CA CA002560649A patent/CA2560649A1/en not_active Abandoned
- 2005-03-24 EP EP05731154A patent/EP1737848A1/en not_active Withdrawn
- 2005-03-24 WO PCT/US2005/009899 patent/WO2005097780A1/en not_active Ceased
- 2005-03-24 UA UAA200611261A patent/UA83738C2/ru unknown
- 2005-03-24 JP JP2007505191A patent/JP2007530580A/ja not_active Abandoned
- 2005-03-24 KR KR1020067019886A patent/KR20060130682A/ko not_active Withdrawn
- 2005-03-24 AU AU2005230934A patent/AU2005230934A1/en not_active Abandoned
- 2005-03-24 MX MXPA06010610A patent/MXPA06010610A/es not_active Application Discontinuation
- 2005-03-24 RU RU2006137717/04A patent/RU2330034C1/ru not_active IP Right Cessation
- 2005-03-24 CN CNA2005800164250A patent/CN1956978A/zh active Pending
- 2005-03-24 BR BRPI0509245-0A patent/BRPI0509245A/pt not_active IP Right Cessation
- 2005-03-25 TW TW094109209A patent/TW200602035A/zh unknown
- 2005-03-28 PA PA20058627601A patent/PA8627601A1/es unknown
-
2006
- 2006-09-07 CR CR8603A patent/CR8603A/es not_active Application Discontinuation
- 2006-09-12 TN TNP2006000278A patent/TNSN06278A1/en unknown
- 2006-09-12 IL IL178031A patent/IL178031A0/en unknown
- 2006-09-14 US US11/520,998 patent/US20070142435A1/en active Granted
- 2006-09-15 ZA ZA200607752A patent/ZA200607752B/en unknown
- 2006-09-22 EC EC2006006878A patent/ECSP066878A/es unknown
- 2006-10-20 MA MA29405A patent/MA28547B1/fr unknown
- 2006-10-23 NO NO20064811A patent/NO20064811L/no not_active Application Discontinuation
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