JP2007529544A5 - - Google Patents

Info

Publication number

JP2007529544A5

JP2007529544A5 JP2007504115A JP2007504115A JP2007529544A5 JP 2007529544 A5 JP2007529544 A5 JP 2007529544A5 JP 2007504115 A JP2007504115 A JP 2007504115A JP 2007504115 A JP2007504115 A JP 2007504115A JP 2007529544 A5 JP2007529544 A5 JP 2007529544A5

Authority

JP

Japan

Prior art keywords

pharmaceutical composition

dosage form

salt

composition according

dimethylsuccinyl

Prior art date

2005-03-17

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
• Discuss

• 239000008194 pharmaceutical composition Substances 0.000 claims 9
• YJEJKUQEXFSVCJ-WRFMNRASSA-N bevirimat Chemical compound C1C[C@H](OC(=O)CC(C)(C)C(O)=O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CC[C@@H](C(=C)C)[C@@H]5[C@H]4CC[C@@H]3[C@]21C YJEJKUQEXFSVCJ-WRFMNRASSA-N 0.000 claims 4
• 239000002552 dosage form Substances 0.000 claims 4
• 150000003839 salts Chemical class 0.000 claims 4
• MBBZMMPHUWSWHV-BDVNFPICSA-N N-methylglucamine Chemical class CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO MBBZMMPHUWSWHV-BDVNFPICSA-N 0.000 claims 3
• 239000004480 active ingredient Substances 0.000 claims 2
• 239000003125 aqueous solvent Substances 0.000 claims 2
• 239000003085 diluting agent Substances 0.000 claims 2
• ODLHGICHYURWBS-LKONHMLTSA-N trappsol cyclo Chemical compound CC(O)COC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)COCC(O)C)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1COCC(C)O ODLHGICHYURWBS-LKONHMLTSA-N 0.000 claims 2
• 229920000858 Cyclodextrin Polymers 0.000 claims 1
• 208000031886 HIV Infections Diseases 0.000 claims 1
• 208000037357 HIV infectious disease Diseases 0.000 claims 1
• 239000003242 anti bacterial agent Substances 0.000 claims 1
• 239000003429 antifungal agent Substances 0.000 claims 1
• 229940121375 antifungal agent Drugs 0.000 claims 1
• 239000002246 antineoplastic agent Substances 0.000 claims 1
• 239000003443 antiviral agent Substances 0.000 claims 1
• 239000003937 drug carrier Substances 0.000 claims 1
• 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 claims 1
• 239000002955 immunomodulating agent Substances 0.000 claims 1
• 229940121354 immunomodulator Drugs 0.000 claims 1
• 230000002584 immunomodulator Effects 0.000 claims 1
• 239000008297 liquid dosage form Substances 0.000 claims 1
• 238000004519 manufacturing process Methods 0.000 claims 1
• 238000000034 method Methods 0.000 claims 1
• 239000006186 oral dosage form Substances 0.000 claims 1
• 239000006201 parenteral dosage form Substances 0.000 claims 1
• 239000006215 rectal suppository Substances 0.000 claims 1
• 229940100618 rectal suppository Drugs 0.000 claims 1
• HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 claims 1
• 239000007787 solid Substances 0.000 claims 1
• 239000000725 suspension Substances 0.000 claims 1