JP2007527403A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2007527403A5 JP2007527403A5 JP2006521161A JP2006521161A JP2007527403A5 JP 2007527403 A5 JP2007527403 A5 JP 2007527403A5 JP 2006521161 A JP2006521161 A JP 2006521161A JP 2006521161 A JP2006521161 A JP 2006521161A JP 2007527403 A5 JP2007527403 A5 JP 2007527403A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48903203P | 2003-07-22 | 2003-07-22 | |
| PCT/US2004/023143 WO2005010048A2 (en) | 2003-07-22 | 2004-07-20 | Rg1 antibodies and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007527403A JP2007527403A (ja) | 2007-09-27 |
| JP2007527403A5 true JP2007527403A5 (enExample) | 2009-12-03 |
| JP4680902B2 JP4680902B2 (ja) | 2011-05-11 |
Family
ID=34102813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006521161A Expired - Fee Related JP4680902B2 (ja) | 2003-07-22 | 2004-07-20 | Ｒｇ１抗体及びその使用 |
Country Status (22)
| Country | Link |
|---|---|
| US (4) | US7335748B2 (enExample) |
| EP (1) | EP1648510B1 (enExample) |
| JP (1) | JP4680902B2 (enExample) |
| KR (1) | KR101215218B1 (enExample) |
| CN (1) | CN1826138B (enExample) |
| AU (1) | AU2004259731B2 (enExample) |
| BR (1) | BRPI0412245A (enExample) |
| CA (1) | CA2532394C (enExample) |
| CR (1) | CR8231A (enExample) |
| EC (1) | ECSP066379A (enExample) |
| ES (1) | ES2427544T3 (enExample) |
| GT (1) | GT200400138A (enExample) |
| IL (1) | IL172871A (enExample) |
| MX (1) | MXPA06000798A (enExample) |
| NO (1) | NO20060843L (enExample) |
| NZ (1) | NZ544911A (enExample) |
| PE (1) | PE20050712A1 (enExample) |
| RU (1) | RU2377252C2 (enExample) |
| TW (1) | TWI353992B (enExample) |
| UY (1) | UY28424A1 (enExample) |
| WO (1) | WO2005010048A2 (enExample) |
| ZA (1) | ZA200601521B (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4680902B2 (ja) * | 2003-07-22 | 2011-05-11 | バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト | Ｒｇ１抗体及びその使用 |
| US7294704B2 (en) | 2003-08-15 | 2007-11-13 | Diadexus, Inc. | Pro108 antibody compositions and methods of use and use of Pro108 to assess cancer risk |
| AR045563A1 (es) | 2003-09-10 | 2005-11-02 | Warner Lambert Co | Anticuerpos dirigidos a m-csf |
| EP2185188B1 (en) | 2007-08-22 | 2014-08-06 | Medarex, L.L.C. | Site-specific attachment of drugs or other agents to engineered antibodies with c-terminal extensions |
| MX2010005683A (es) * | 2007-11-30 | 2010-06-11 | Bristol Myers Squibb Co | Conjugados de anticuerpos anti-rg-1. |
| US20110059091A1 (en) * | 2008-02-04 | 2011-03-10 | Xiao-Jia Chang | Inhibitors of oncogenic isoforms and uses thereof |
| US9260525B2 (en) | 2008-02-04 | 2016-02-16 | Xiao-Jia Chang | Antibody molecules to oncogenic isoforms of fibroblast growth factor receptor-2 and uses thereof |
| US8394922B2 (en) | 2009-08-03 | 2013-03-12 | Medarex, Inc. | Antiproliferative compounds, conjugates thereof, methods therefor, and uses thereof |
| CN103201287B (zh) * | 2010-08-12 | 2016-04-13 | 艾托生物有限公司 | 成纤维细胞生长因子受体2的致癌异构体的抗体分子及其用途 |
| US8852599B2 (en) | 2011-05-26 | 2014-10-07 | Bristol-Myers Squibb Company | Immunoconjugates, compositions for making them, and methods of making and use |
| SMT201700137T1 (it) | 2012-02-13 | 2017-05-08 | Bristol Myers Squibb Co | Composti di endiini, loro coniugati, e loro usi e metodi |
| LT2956173T (lt) | 2013-02-14 | 2017-06-26 | Bristol-Myers Squibb Company | Tubulizino junginiai, gavimo ir panaudojimo būdai |
| KR20160068738A (ko) | 2013-08-14 | 2016-06-15 | 윌리엄 마쉬 라이스 유니버시티 | 운시알라마이신의 유도체, 합성 방법 및 항종양 제제로서 이들의 용도 |
| US10357578B2 (en) | 2014-05-13 | 2019-07-23 | Paul Scherrer Institut | Production of 43SC radionuclide and radiopharmaceuticals thereof for use in positron emission tomography |
| US10077287B2 (en) | 2014-11-10 | 2018-09-18 | Bristol-Myers Squibb Company | Tubulysin analogs and methods of making and use |
| PL3221346T3 (pl) | 2014-11-21 | 2021-03-08 | Bristol-Myers Squibb Company | Przeciwciała ze zmodyfikowanym regionem stałym łańcucha ciężkiego |
| KR20170102981A (ko) | 2015-01-14 | 2017-09-12 | 브리스톨-마이어스 스큅 컴퍼니 | 헤테로아릴렌-가교된 벤조디아제핀 이량체, 그의 접합체, 및 제조 및 사용 방법 |
| US20180362619A1 (en) | 2015-12-21 | 2018-12-20 | Bristol-Myers Squibb Company | Variant antibodies for site-specific conjugation |
| JP2019518013A (ja) | 2016-05-10 | 2019-06-27 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | 安定性が向上したツブリシン類似体の抗体薬物結合体 |
| ES2902179T3 (es) | 2016-08-19 | 2022-03-25 | Bristol Myers Squibb Co | Compuestos de seco-ciclopropapirroloindol, conjugados de anticuerpo-fármaco de los mismos y métodos de elaboración y uso |
| WO2018075842A1 (en) | 2016-10-20 | 2018-04-26 | Bristol-Myers Squibb Company | Condensed benzodiazepine derivatives and conjugates made therefrom |
| US20200299400A1 (en) | 2017-05-25 | 2020-09-24 | Bristol-Myers Squibb Company | Antibodies comprising modified heavy constant regions |
| US10487084B2 (en) | 2017-08-16 | 2019-11-26 | Bristol-Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having a heterobiaryl moiety, conjugates thereof, and methods and uses therefor |
| US10508115B2 (en) | 2017-08-16 | 2019-12-17 | Bristol-Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor |
| US10472361B2 (en) | 2017-08-16 | 2019-11-12 | Bristol-Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having a benzotriazole moiety, conjugates thereof, and methods and uses therefor |
| US10494370B2 (en) | 2017-08-16 | 2019-12-03 | Bristol-Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having a pyridine or pyrazine moiety, conjugates thereof, and methods and uses therefor |
| US10457681B2 (en) | 2017-08-16 | 2019-10-29 | Bristol_Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having a tricyclic moiety, conjugates thereof, and methods and uses therefor |
| WO2019209811A1 (en) | 2018-04-24 | 2019-10-31 | Bristol-Myers Squibb Company | Macrocyclic toll-like receptor 7 (tlr7) agonists |
| SG11202011739SA (en) | 2018-05-29 | 2020-12-30 | Bristol Myers Squibb Co | Modified self-immolating moieties for use in prodrugs and conjugates and methods of using and making |
| US11554120B2 (en) | 2018-08-03 | 2023-01-17 | Bristol-Myers Squibb Company | 1H-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (TLR7) agonists and methods and uses therefor |
| JP2022513653A (ja) | 2018-11-28 | 2022-02-09 | ブリストル－マイヤーズ スクイブ カンパニー | 修飾された重鎖定常領域を含む抗体 |
| KR102861586B1 (ko) | 2018-11-30 | 2025-09-17 | 브리스톨-마이어스 스큅 컴퍼니 | 글루타민-함유 경쇄 c-말단 연장부를 포함하는 항체, 그의 접합체, 및 방법 및 용도 |
| JP7514836B2 (ja) | 2018-12-12 | 2024-07-11 | ブリストル－マイヤーズ スクイブ カンパニー | トランスグルタミナーゼによるコンジュゲーションのための改変抗体、ならびにそのコンジュゲート、方法および用途 |
| US20240377413A1 (en) | 2019-09-16 | 2024-11-14 | Bristol-Myers Squibb Company | Dual capture method for analysis of antibody-drug conjugates |
| WO2025058000A1 (ja) * | 2023-09-13 | 2025-03-20 | 東レ株式会社 | 癌の治療、予防及び／又は診断用医薬組成物 |
| WO2025188694A1 (en) | 2024-03-05 | 2025-09-12 | Bristol-Myers Squibb Company | Tricyclic tlr7 agonists and uses thereof |
| WO2025188693A1 (en) | 2024-03-05 | 2025-09-12 | Bristol-Myers Squibb Company | Bicyclic tlr7 agonists and uses thereof |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5246692A (en) | 1986-09-05 | 1993-09-21 | The United States Of America As Represented By The Secretary Of Health And Human Services | Backbone polysubstituted chelates for forming a metal chelate-protein conjugate |
| US4831175A (en) | 1986-09-05 | 1989-05-16 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Backbone polysubstituted chelates for forming a metal chelate-protein conjugate |
| US6150584A (en) * | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US6300129B1 (en) | 1990-08-29 | 2001-10-09 | Genpharm International | Transgenic non-human animals for producing heterologous antibodies |
| US5877397A (en) | 1990-08-29 | 1999-03-02 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5871969A (en) | 1996-02-12 | 1999-02-16 | Human Genome Sciences, Inc. | Nucleic acids encoding human neuronal attachment factor-1 |
| US6177244B1 (en) * | 1996-05-10 | 2001-01-23 | Beth Israel Deaconess Medical Center Inc. | NPG-1 gene that is differentially expressed in prostate tumors |
| US5804382A (en) | 1996-05-10 | 1998-09-08 | Beth Israel Deaconess Medical Center, Inc. | Methods for identifying differentially expressed genes and differences between genomic nucleic acid sequences |
| US6287777B1 (en) * | 1996-05-10 | 2001-09-11 | Beth Israel Deaconess Medical Center | NPG-1 gene that is differentially expressed in prostate tumors |
| WO1999046281A2 (en) | 1998-03-10 | 1999-09-16 | Genentech, Inc. | Novel polypeptides and nucleic acids encoding the same |
| WO1998045442A2 (en) | 1997-04-10 | 1998-10-15 | Zymogenetics, Inc. | Secreted f-spondin homologs |
| AU7376698A (en) | 1997-05-09 | 1998-11-27 | Smithkline Beecham Corporation | Integrin ligand, human mindin |
| EP1126877A4 (en) | 1998-10-19 | 2003-05-28 | Diadexus Inc | METHOD OF DIAGNOSIS, MONITORING, STADIUM CLASSIFICATION, VISUALIZATION AND TREATMENT OF PROSTATE CANCER |
| EE05627B1 (et) * | 1998-12-23 | 2013-02-15 | Pfizer Inc. | CTLA-4 vastased inimese monoklonaalsed antikehad |
| US6824780B1 (en) * | 1999-10-29 | 2004-11-30 | Genentech, Inc. | Anti-tumor antibody compositions and methods of use |
| US6682902B2 (en) * | 1999-12-16 | 2004-01-27 | Schering Aktiengesellschaft | DNA encoding a novel RG1 polypeptide |
| US20030059427A1 (en) | 2000-04-28 | 2003-03-27 | Force Walker R. | Isolation and characterization of highly active anti-CD40 antibody |
| RU2192889C1 (ru) * | 2001-03-16 | 2002-11-20 | Эпштейн Олег Ильич | Лекарственное средство и способ лечения заболеваний предстательной железы |
| EP2011802A3 (en) * | 2001-04-27 | 2009-04-15 | Kyowa Hakko Kirin Co., Ltd. | Anti-CD40 monoclonal antibody |
| IL149701A0 (en) | 2001-05-23 | 2002-11-10 | Pfizer Prod Inc | Use of anti-ctla-4 antibodies |
| GB0124317D0 (en) | 2001-10-10 | 2001-11-28 | Celltech R&D Ltd | Biological products |
| JP4680902B2 (ja) * | 2003-07-22 | 2011-05-11 | バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト | Ｒｇ１抗体及びその使用 |
-
2004
- 2004-07-20 JP JP2006521161A patent/JP4680902B2/ja not_active Expired - Fee Related
- 2004-07-20 KR KR1020067001366A patent/KR101215218B1/ko not_active Expired - Fee Related
- 2004-07-20 CA CA 2532394 patent/CA2532394C/en not_active Expired - Fee Related
- 2004-07-20 GT GT200400138A patent/GT200400138A/es unknown
- 2004-07-20 CN CN2004800211789A patent/CN1826138B/zh not_active Expired - Fee Related
- 2004-07-20 UY UY28424A patent/UY28424A1/es not_active Application Discontinuation
- 2004-07-20 MX MXPA06000798A patent/MXPA06000798A/es active IP Right Grant
- 2004-07-20 NZ NZ544911A patent/NZ544911A/en not_active IP Right Cessation
- 2004-07-20 WO PCT/US2004/023143 patent/WO2005010048A2/en not_active Ceased
- 2004-07-20 EP EP04778578.7A patent/EP1648510B1/en not_active Expired - Lifetime
- 2004-07-20 US US10/895,183 patent/US7335748B2/en not_active Expired - Fee Related
- 2004-07-20 PE PE2004000690A patent/PE20050712A1/es not_active Application Discontinuation
- 2004-07-20 ES ES04778578T patent/ES2427544T3/es not_active Expired - Lifetime
- 2004-07-20 AU AU2004259731A patent/AU2004259731B2/en not_active Ceased
- 2004-07-20 TW TW93121655A patent/TWI353992B/zh not_active IP Right Cessation
- 2004-07-20 BR BRPI0412245 patent/BRPI0412245A/pt not_active IP Right Cessation
- 2004-07-20 RU RU2006105339A patent/RU2377252C2/ru not_active IP Right Cessation
-
2005
- 2005-12-28 IL IL17287105A patent/IL172871A/en not_active IP Right Cessation
-
2006
- 2006-02-13 CR CR8231A patent/CR8231A/es not_active Application Discontinuation
- 2006-02-16 EC ECSP066379 patent/ECSP066379A/es unknown
- 2006-02-21 NO NO20060843A patent/NO20060843L/no not_active Application Discontinuation
- 2006-02-21 ZA ZA200601521A patent/ZA200601521B/en unknown
-
2007
- 2007-10-30 US US11/981,219 patent/US7611706B2/en not_active Expired - Fee Related
- 2007-10-30 US US11/981,123 patent/US7608263B2/en not_active Expired - Fee Related
-
2009
- 2009-09-15 US US12/560,363 patent/US20100081795A1/en not_active Abandoned