JP2007522137A - ざ瘡を治療するための光線力学療法 - Google Patents

ざ瘡を治療するための光線力学療法 Download PDF

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Publication number
JP2007522137A
JP2007522137A JP2006551694A JP2006551694A JP2007522137A JP 2007522137 A JP2007522137 A JP 2007522137A JP 2006551694 A JP2006551694 A JP 2006551694A JP 2006551694 A JP2006551694 A JP 2006551694A JP 2007522137 A JP2007522137 A JP 2007522137A
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JP
Japan
Prior art keywords
photosensitizer
acne
skin
topical
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006551694A
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English (en)
Japanese (ja)
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JP2007522137A5 (https=
Inventor
アラン エイチ クラウドゥー
ヘルマ シー ネインドルフ
ジン−ソン タオ
モーガン チュン ラム
パトリック マーク カリー
ヴァレリー ルビンチック
デイビッド ダブリュー． シー． ハント
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Novelion Therapeutics Inc
Original Assignee
QLT Inc
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Publication date
Application filed by QLT Inc filed Critical QLT Inc
Publication of JP2007522137A publication Critical patent/JP2007522137A/ja
Publication of JP2007522137A5 publication Critical patent/JP2007522137A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0076—PDT with expanded (metallo)porphyrins, i.e. having more than 20 ring atoms, e.g. texaphyrins, sapphyrins, hexaphyrins, pentaphyrins, porphocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Radiation-Therapy Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2006551694A 2004-02-06 2005-02-04 ざ瘡を治療するための光線力学療法 Pending JP2007522137A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA002457214A CA2457214A1 (en) 2004-02-06 2004-02-06 Photodynamic therapy for the treatment of acne
CA002470403A CA2470403A1 (en) 2004-02-06 2004-06-09 Photodynamic therapy for the treatment of hyperactive sebaceous gland disorders
PCT/CA2005/000141 WO2005074987A1 (en) 2004-02-06 2005-02-04 Photodynamic therapy for the treatment of acne

Publications (2)

Publication Number Publication Date
JP2007522137A true JP2007522137A (ja) 2007-08-09
JP2007522137A5 JP2007522137A5 (https=) 2008-03-27

Family

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Family Applications (1)

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JP2006551694A Pending JP2007522137A (ja) 2004-02-06 2005-02-04 ざ瘡を治療するための光線力学療法

Country Status (7)

Country Link
US (2) US20100056982A1 (https=)
EP (3) EP2659909A3 (https=)
JP (1) JP2007522137A (https=)
AU (1) AU2005209955A1 (https=)
BR (1) BRPI0507406A (https=)
CA (3) CA2457214A1 (https=)
WO (1) WO2005074987A1 (https=)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010071230A1 (ja) 2008-12-17 2010-06-24 学校法人慶應義塾 細胞特異的能動集積性を有する光線力学療法剤
JP2011513213A (ja) * 2008-02-25 2011-04-28 ロレアル 皮膚および／または髪の外観を改善するための、光線とリパーゼにより生物学的に変換可能な化合物との組合せ
JP2013532035A (ja) * 2010-07-09 2013-08-15 フォトキュア エイエスエイ 光力学的治療または光力学的診断で使用する乾燥組成物および当該乾燥組成物を含む装置
JP2016525540A (ja) * 2013-07-23 2016-08-25 ドンスン ファーム カンパニー リミテッド にきび治療、予防または改善に有効なクロリンｅ６
JP2023529257A (ja) * 2020-04-14 2023-07-10 インスティテュート フランセス デ ルシェルシェ プル レクスプロイテーション デ ラ メール （イフレメー） 光線力学療法におけるスケレトネマ（Ｓｋｅｌｅｔｏｎｅｍａ）の極性抽出物の使用

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AU2011253786B2 (en) * 2004-06-09 2014-10-09 Valeant Pharmaceuticals International, Inc. Photodynamic therapy for the treatment of hyperactive sebaceous gland disorders using topically applied hydrophobic green porphyrins
JP2008501727A (ja) * 2004-06-09 2008-01-24 キュー エル ティー インク． 外用塗布した疎水性緑色ポルフィリンを用いた機能亢進性皮脂腺障害を治療するための光線力学的療法
US20090131499A1 (en) * 2007-11-15 2009-05-21 Ceramoptec Industries Inc. Photodynamic therapy for skin related problems
WO2009093144A2 (en) * 2008-01-25 2009-07-30 Qlt, Inc.Lau Photodynamic therapy of sebaceous gland disorders
US8815931B2 (en) * 2009-04-28 2014-08-26 Biolitec Pharma Marketing Ltd Oral formulations for tetrapyrrole derivatives
SI2440199T1 (sl) * 2009-06-11 2016-05-31 Photocure Asa Poltrdni sestavki in farmacevtski proizvodi
AU2010270797B2 (en) 2009-07-08 2015-03-19 Dermira (Canada), Inc. TOFA analogs useful in treating dermatological disorders or conditions
BR112013017953A2 (pt) 2011-01-13 2017-08-29 Quadra Logic Tech Inc Composição farmacêutica, formulação tópica, método, e, composição fotossensibilizadora
US9687669B2 (en) 2011-11-09 2017-06-27 John Stephan Wearable light therapy apparatus
US20130281913A1 (en) 2012-04-20 2013-10-24 Klox Technologies Inc. Biophotonic compositions and methods for providing biophotonic treatment
CN104703624A (zh) * 2012-07-11 2015-06-10 德米拉股份有限公司 局部递送光敏剂的药物组合物及其应用
RU2015141708A (ru) * 2013-03-01 2017-04-06 Клокс Текнолоджиз Инк. Фототерапевтическое устройство, способ и применение
KR20150004092A (ko) * 2013-07-02 2015-01-12 제너럴바이오(주) 칼란코에 추출물이 포함된 항산화 액상 조성물
HK1219890A1 (zh) 2013-07-03 2017-04-21 广东科洛克生物医药集团有限公司 治疗不癒合伤口的组合物和方法
JP6595484B2 (ja) * 2013-12-20 2019-10-23 ガルデルマ・リサーチ・アンド・デヴェロップメント 光損傷皮膚のパルス光力学的処置
JP2017509433A (ja) 2014-04-01 2017-04-06 クロックス テクノロジーズ インコーポレイテッドＫｌｏｘ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ． 組織充填剤組成物および使用方法
US9950147B2 (en) * 2014-09-12 2018-04-24 Je Matadi, Inc. Apparatus and method for administering a skin care composition
US20180117355A1 (en) * 2015-05-12 2018-05-03 Klox Technologies Inc. Devices and methods for phototherapy
US20190083809A1 (en) 2016-07-27 2019-03-21 Z2020, Llc Componentry and devices for light therapy delivery and methods related thereto
KR20220061106A (ko) 2019-08-02 2022-05-12 코이트 헬스 오와이 전신적으로 적용하는 항생제의 항균 작용을 강화하는 방법
CN112451862B (zh) * 2020-11-24 2023-03-28 深圳罗兹曼国际转化医学研究院 光动力治疗系统及其控制方法
MY208934A (en) * 2021-10-06 2025-06-12 Tunku Abdul Rahman Univ Of Management And Technology Tar Umt Treating skin diseases using a photodynamic therapy (pdt) and a topical agent photosensitizer formulation
KR20250001702A (ko) * 2023-06-29 2025-01-07 주식회사 루트로닉 여드름 치료를 위한 레이저 치료 장치 및 이를 이용한 치료 방법

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WO2003086460A2 (en) * 2002-04-05 2003-10-23 Candela Corporation High fluence rate activation of photosensitizers for dermatological applications

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WO2003086460A2 (en) * 2002-04-05 2003-10-23 Candela Corporation High fluence rate activation of photosensitizers for dermatological applications

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011513213A (ja) * 2008-02-25 2011-04-28 ロレアル 皮膚および／または髪の外観を改善するための、光線とリパーゼにより生物学的に変換可能な化合物との組合せ
WO2010071230A1 (ja) 2008-12-17 2010-06-24 学校法人慶應義塾 細胞特異的能動集積性を有する光線力学療法剤
JP2013532035A (ja) * 2010-07-09 2013-08-15 フォトキュア エイエスエイ 光力学的治療または光力学的診断で使用する乾燥組成物および当該乾燥組成物を含む装置
JP2016525540A (ja) * 2013-07-23 2016-08-25 ドンスン ファーム カンパニー リミテッド にきび治療、予防または改善に有効なクロリンｅ６
JP2023529257A (ja) * 2020-04-14 2023-07-10 インスティテュート フランセス デ ルシェルシェ プル レクスプロイテーション デ ラ メール （イフレメー） 光線力学療法におけるスケレトネマ（Ｓｋｅｌｅｔｏｎｅｍａ）の極性抽出物の使用
JP7793148B2 (ja) 2020-04-14 2026-01-05 インスティテュート フランセス デ ルシェルシェ プル レクスプロイテーション デ ラ メール （イフレメー） 光線力学療法におけるスケレトネマ（Ｓｋｅｌｅｔｏｎｅｍａ）の極性抽出物の使用

Also Published As

Publication number Publication date
EP2659909A3 (en) 2014-08-13
US20080096857A1 (en) 2008-04-24
WO2005074987A1 (en) 2005-08-18
EP2659909A2 (en) 2013-11-06
CA2554591A1 (en) 2005-08-18
CA2554591C (en) 2014-12-02
EP1720576A4 (en) 2010-12-22
BRPI0507406A (pt) 2007-06-26
EP2494989A1 (en) 2012-09-05
CA2470403A1 (en) 2005-08-06
CA2457214A1 (en) 2005-08-06
EP1720576A1 (en) 2006-11-15
US20100056982A1 (en) 2010-03-04
AU2005209955A1 (en) 2005-08-18

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