BRPI0507406A - método de tratamento de acne vulgaris, e, uso de um fotossensibilizante de porfirina verde e solubilizador - Google Patents

método de tratamento de acne vulgaris, e, uso de um fotossensibilizante de porfirina verde e solubilizador

Info

Publication number
BRPI0507406A
BRPI0507406A BRPI0507406-1A BRPI0507406A BRPI0507406A BR PI0507406 A BRPI0507406 A BR PI0507406A BR PI0507406 A BRPI0507406 A BR PI0507406A BR PI0507406 A BRPI0507406 A BR PI0507406A
Authority
BR
Brazil
Prior art keywords
acne vulgaris
solubilizer
green porphyrin
treating acne
photosensitizer
Prior art date
Application number
BRPI0507406-1A
Other languages
English (en)
Inventor
Alain H Curaudeau
Herma C Neyndorff
Jing-Song Tao
Morgan Chun Lam
Patrick Mark Curry
Valery Rubinchik
David W C Hunt
Original Assignee
Quadra Logic Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quadra Logic Tech Inc filed Critical Quadra Logic Tech Inc
Publication of BRPI0507406A publication Critical patent/BRPI0507406A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0076—PDT with expanded (metallo)porphyrins, i.e. having more than 20 ring atoms, e.g. texaphyrins, sapphyrins, hexaphyrins, pentaphyrins, porphocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Radiation-Therapy Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

MéTODO DE TRATAMENTO DE ACNE VULGARIS, E, USO DE UM FOTOSSENSIBILIZANTE DE PORFIRINA VERDE E SOLUBILIZADOR O presente método envolve o tratamento fotodinâmico de acne vulgaris. O método envolve a administração tópica de uma composição de fotossensibilizante compreendendo porfirinas verdes hidrofóbicas como lemuteporfina, polietileno glicol e melhoradores da penetração na pele, como álcool oleílico, e TRANSCUTOL <sym> a pele afetada com acne e subsequente exposição desta pele a energia de um comprimento de onda de ativação do fotossensibilizante.
BRPI0507406-1A 2004-02-06 2005-02-04 método de tratamento de acne vulgaris, e, uso de um fotossensibilizante de porfirina verde e solubilizador BRPI0507406A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA002457214A CA2457214A1 (en) 2004-02-06 2004-02-06 Photodynamic therapy for the treatment of acne
CA002470403A CA2470403A1 (en) 2004-02-06 2004-06-09 Photodynamic therapy for the treatment of hyperactive sebaceous gland disorders
PCT/CA2005/000141 WO2005074987A1 (en) 2004-02-06 2005-02-04 Photodynamic therapy for the treatment of acne

Publications (1)

Publication Number Publication Date
BRPI0507406A true BRPI0507406A (pt) 2007-06-26

Family

ID=34839264

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0507406-1A BRPI0507406A (pt) 2004-02-06 2005-02-04 método de tratamento de acne vulgaris, e, uso de um fotossensibilizante de porfirina verde e solubilizador

Country Status (7)

Country Link
US (2) US20100056982A1 (pt)
EP (3) EP1720576A4 (pt)
JP (1) JP2007522137A (pt)
AU (1) AU2005209955A1 (pt)
BR (1) BRPI0507406A (pt)
CA (3) CA2457214A1 (pt)
WO (1) WO2005074987A1 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ551636A (en) * 2004-06-09 2009-12-24 Quadra Logic Tech Inc Photodynamic therapy for the treatment of hyperactive sebaceous gland disorders using topically applied hydrophobic green porphyrins
AU2011253786B2 (en) * 2004-06-09 2014-10-09 Valeant Pharmaceuticals International, Inc. Photodynamic therapy for the treatment of hyperactive sebaceous gland disorders using topically applied hydrophobic green porphyrins
US20090131499A1 (en) * 2007-11-15 2009-05-21 Ceramoptec Industries Inc. Photodynamic therapy for skin related problems
WO2009093144A2 (en) * 2008-01-25 2009-07-30 Qlt, Inc.Lau Photodynamic therapy of sebaceous gland disorders
FR2927800A1 (fr) * 2008-02-25 2009-08-28 Oreal Association d'un rayonnement lumineux et d'un compose bioconvertible par la lipase pour ameliorer l'apparence de la peau et/ou du cheveu.
JP5808107B2 (ja) 2008-12-17 2015-11-10 学校法人慶應義塾 細胞特異的能動集積性を有する光線力学療法剤
US8815931B2 (en) * 2009-04-28 2014-08-26 Biolitec Pharma Marketing Ltd Oral formulations for tetrapyrrole derivatives
WO2010142457A1 (en) * 2009-06-11 2010-12-16 Photocure Asa Semi-solid compositions and pharmaceutical products
KR101722289B1 (ko) 2009-07-08 2017-03-31 데르미라 (캐나다), 인코포레이티드 피부과 질환 또는 증상의 치료에 유용한 ｔｏｆａ 유사체
AU2011275695B2 (en) * 2010-07-09 2014-07-31 Photocure Asa Dry compositions and devices containing such dry compositions for use in photodynamic therapy or photodynamic diagnosis
EP2663285A2 (en) 2011-01-13 2013-11-20 Qlt Inc. Pharmaceutical compositions for topical delivery of photosensitizers and uses thereof
US9687669B2 (en) 2011-11-09 2017-06-27 John Stephan Wearable light therapy apparatus
US20130281913A1 (en) 2012-04-20 2013-10-24 Klox Technologies Inc. Biophotonic compositions and methods for providing biophotonic treatment
WO2014011875A1 (en) 2012-07-11 2014-01-16 Dermira, Inc. Pharmaceutical compositions for topical delivery of photosensitizers and uses thereof
US20140303547A1 (en) * 2013-03-01 2014-10-09 Klox Technologies Inc. Phototherapeutic device, method and use
KR20150004092A (ko) * 2013-07-02 2015-01-12 제너럴바이오(주) 칼란코에 추출물이 포함된 항산화 액상 조성물
MX366292B (es) 2013-07-03 2019-07-04 Klox Tech Inc Composiciones biofotónicas que comprenden un cromóforo y un agente gelificante para el tratamiento de heridas.
KR101623553B1 (ko) * 2013-07-23 2016-05-23 동성제약주식회사 여드름 치료, 예방 또는 개선에 유효한 클로린 e6
US10716855B2 (en) * 2013-12-20 2020-07-21 Galderma Research & Development Pulse photodynamic treatment of photodamaged skin
CN106413766A (zh) 2014-04-01 2017-02-15 克洛克斯科技公司 组织填料组合物及使用方法
US9950147B2 (en) * 2014-09-12 2018-04-24 Je Matadi, Inc. Apparatus and method for administering a skin care composition
US20180117355A1 (en) * 2015-05-12 2018-05-03 Klox Technologies Inc. Devices and methods for phototherapy
US20190083809A1 (en) 2016-07-27 2019-03-21 Z2020, Llc Componentry and devices for light therapy delivery and methods related thereto
CN112451862B (zh) * 2020-11-24 2023-03-28 深圳罗兹曼国际转化医学研究院 光动力治疗系统及其控制方法
WO2023059180A1 (en) * 2021-10-06 2023-04-13 Tunku Abdul Rahman University Of Management And Technology (Tar Umt) Treating skin diseases using a photodynamic therapy (pdt) and a topical agent photosensitizer formulation

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861764A (en) 1986-11-17 1989-08-29 Macro Chem. Corp. Percutaneous absorption enhancers, compositions containing same and method of use
US5171749A (en) 1987-01-20 1992-12-15 University Of British Columbia Wavelength-specific cytotoxic agents
US5095030A (en) * 1987-01-20 1992-03-10 University Of British Columbia Wavelength-specific cytotoxic agents
US4920143A (en) 1987-04-23 1990-04-24 University Of British Columbia Hydro-monobenzoporphyrin wavelength-specific cytotoxic agents
US4883790A (en) * 1987-01-20 1989-11-28 University Of British Columbia Wavelength-specific cytotoxic agents
US5283255A (en) * 1987-01-20 1994-02-01 The University Of British Columbia Wavelength-specific cytotoxic agents
GB8805849D0 (en) 1988-03-11 1988-04-13 Efamol Holdings Porphyrins & cancer treatment
US5955490A (en) * 1989-07-28 1999-09-21 Queen's University At Kingston Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
US6492420B2 (en) * 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
IL116126A0 (en) 1995-11-24 1996-01-31 Yeda Res & Dev Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them
US5880145A (en) * 1997-05-07 1999-03-09 The University Of British Columbia Class of benzoporphyrin derivative photoactive compounds
PT983272E (pt) 1997-05-07 2004-03-31 Univ British Columbia Nova classe de compostos fotoactivos derivados de benzoporfirina
CA2284879C (en) 1997-05-07 2005-10-25 Qlt Phototherapeutics, Inc. Ethylene glycol esters of monohydrobenzoporphyrin derivatives as photoactive agents
US6004821A (en) 1998-03-07 1999-12-21 Levine; Robert A. Method and apparatus for performing chemical, qualitative, quantitative, and semi-quantitative analyses of a urine sample
JP2002526128A (ja) * 1998-07-09 2002-08-20 キュアライト・リミテッド にきび及び脂漏症のために有効な高エネルギ光力学治療装置及び方法
EP1100490B1 (en) * 1998-07-28 2006-12-13 Susan Bershad Short contact treatment of acne and photoaging with topical retinoids
US6887260B1 (en) * 1998-11-30 2005-05-03 Light Bioscience, Llc Method and apparatus for acne treatment
US6183773B1 (en) * 1999-01-04 2001-02-06 The General Hospital Corporation Targeting of sebaceous follicles as a treatment of sebaceous gland disorders
IL133253A0 (en) 1999-12-01 2001-04-30 Yeda Res & Dev Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
GB0005855D0 (en) 2000-03-10 2000-05-03 Scotia Holdings Plc Compounds for pdt
GB2360459B (en) 2000-03-23 2002-08-07 Photo Therapeutics Ltd Therapeutic light source and method
GB2361430A (en) 2000-04-17 2001-10-24 Photo Therapeutics Ltd Therapeutic discharge lamps
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
EP2269645A3 (en) 2000-08-16 2011-01-12 The General Hospital Corporation doing business as Massachusetts General Hospital Topical aminolevulinic acid-photodynamic therapy for acne vulgaris
GB2368020A (en) * 2000-10-18 2002-04-24 Icn Photonics Ltd Treatment of acne vulgaris skin condition by irradiation with light of specific wavelengths to target specific chromophores & stimulate collagen production
US6984395B2 (en) * 2001-04-11 2006-01-10 Qlt, Inc. Drug delivery system for hydrophobic drugs
US7018396B2 (en) * 2001-08-07 2006-03-28 New England Medical Center Hospitals, Inc. Method of treating acne
EP1441767A1 (en) 2001-11-09 2004-08-04 QLT Inc. Compositions comprising a photosensitizer and a skin-penetration enhancer and their use in photodynamic treatment
WO2003086460A2 (en) 2002-04-05 2003-10-23 Candela Corporation High fluence rate activation of photosensitizers for dermatological applications
US20040228822A1 (en) * 2003-05-16 2004-11-18 Khaiat Alain V. Topical treatment of skin conditions

Also Published As

Publication number Publication date
EP2659909A3 (en) 2014-08-13
EP2659909A2 (en) 2013-11-06
CA2457214A1 (en) 2005-08-06
CA2470403A1 (en) 2005-08-06
EP1720576A1 (en) 2006-11-15
CA2554591A1 (en) 2005-08-18
JP2007522137A (ja) 2007-08-09
CA2554591C (en) 2014-12-02
AU2005209955A1 (en) 2005-08-18
EP1720576A4 (en) 2010-12-22
US20080096857A1 (en) 2008-04-24
US20100056982A1 (en) 2010-03-04
EP2494989A1 (en) 2012-09-05
WO2005074987A1 (en) 2005-08-18

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 12A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]