JP2007521294A - 初期血管内凝血を選択的に分解する組成物及び方法 - Google Patents
初期血管内凝血を選択的に分解する組成物及び方法 Download PDFInfo
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- 108700012359 toxins Proteins 0.000 description 1
- 102000003601 transglutaminase Human genes 0.000 description 1
- 239000002753 trypsin inhibitor Substances 0.000 description 1
- 210000003606 umbilical vein Anatomy 0.000 description 1
- 208000021331 vascular occlusion disease Diseases 0.000 description 1
- 230000008728 vascular permeability Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/18—Erythrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/611,723 US7041287B2 (en) | 1998-05-21 | 2003-07-01 | Compositions and methods for selective dissolution of nascent intravascular blood clots |
| PCT/US2004/020660 WO2005004804A2 (en) | 2003-07-01 | 2004-06-28 | Compositions and methods for selective dissolution of nascent intravascular blood clots |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007521294A true JP2007521294A (ja) | 2007-08-02 |
| JP2007521294A5 JP2007521294A5 (enExample) | 2007-09-13 |
Family
ID=34062346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006518692A Pending JP2007521294A (ja) | 2003-07-01 | 2004-06-28 | 初期血管内凝血を選択的に分解する組成物及び方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7041287B2 (enExample) |
| EP (1) | EP1648497A2 (enExample) |
| JP (1) | JP2007521294A (enExample) |
| AU (1) | AU2004255196B2 (enExample) |
| CA (1) | CA2530529A1 (enExample) |
| WO (1) | WO2005004804A2 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1093378A4 (en) * | 1998-05-21 | 2001-10-10 | Univ Pennsylvania | COMPOSITIONS AND TECHNIQUES FOR PREVENTING AND TREATING ANARCHIC FORMATION OF INTRAVASCULAR FIBRINOUS CLOTS |
| US7674466B2 (en) * | 1999-08-05 | 2010-03-09 | The Trustees Of The University Of Pennsylvania | Targeting and prolonging association of drugs to the luminal surface of the pulmonary vascular endothelial cells using antibodies that bind to ICAM-1 |
| EP1339427A4 (en) * | 2000-11-01 | 2004-09-15 | Elusys Therapeutics Inc | PROCESS FOR PRODUCING BISPECIFIC MOLECULES BY TRANSEPISSANCE OF PROTEINS |
| US20070003552A1 (en) * | 2002-07-09 | 2007-01-04 | Gebbink Martijn F B | Cross-beta structure comprising amyloid binding proteins and methods for detection of the cross-beta structure, for modulating cross-beta structures fibril formation and for modulating cross-beta structure-mediated toxicity and method for interfering with blood coagulation |
| EP1380290A1 (en) | 2002-07-09 | 2004-01-14 | Universitair Medisch Centrum Utrecht | Cross-beta structure pathway and its therapeutic relevance |
| US20080317761A1 (en) * | 2004-04-28 | 2008-12-25 | The Trustees Of The University Of Pennsylvania | Peptide-Mediated Protein Transduction Into Cells of the Hematopoietic Lineage |
| WO2006050177A2 (en) * | 2004-10-29 | 2006-05-11 | The Regents Of The University Of Colorado | Antibodies that bind urokinase-type plasminogen activator and epitopes therefor |
| US20090202980A1 (en) * | 2005-03-21 | 2009-08-13 | Crossbeta Biosciences B.V. | Cross-Beta Structure Comprising Amyloid Binding Proteins and Methods for Detection of the Cross-Beta Structure, for Modulating Cross-Beta Structures Fibril Formation and for Modulating Cross-Beta Structure-Mediated Toxicity and Method for Interfering With Blood Coagulation |
| US8114832B2 (en) * | 2005-07-13 | 2012-02-14 | Crossbeta Biosciences B.V. | Method for detecting and/or removing a protein comprising a cross-beta structure from a pharmaceutical composition |
| WO2007008072A2 (en) * | 2005-07-13 | 2007-01-18 | Crossbeta Biosciences B.V. | CROSS-ß STRUCTURE BINDING COMPOUNDS |
| US20080249606A1 (en) * | 2005-07-13 | 2008-10-09 | Martijn Frans Ben Gerard Gebbink | Methods for Determining the Effect of a Treatment on the Cross-Beta Structure Content of a Protein; Selection of Treatments and Uses Thereof |
| WO2008039206A2 (en) * | 2005-10-05 | 2008-04-03 | The Trustees Of The University Of Pennsylvania | Fusion proteins for inhibition and dissolution of coagulation |
| WO2007108675A1 (en) * | 2006-03-17 | 2007-09-27 | Crossbeta Biosciences B.V. | Methods of binding of cross-beta structures by chaperones |
| WO2008147526A1 (en) * | 2007-05-23 | 2008-12-04 | The Trustees Of The University Of Pennsylvania | Targeted carriers for intracellular drug delivery |
| EP2058001A1 (en) * | 2007-11-08 | 2009-05-13 | Crossbeta Biosciences B.V. | Enhancement of immunogenicity of antigens |
| EP2058000A1 (en) * | 2007-11-08 | 2009-05-13 | Crossbeta Biosciences B.V. | Immunogenic compositions capable of activating T cells |
| US8333973B2 (en) * | 2008-01-02 | 2012-12-18 | The Trustees Of The University Of Pennsylvania | Targeting recombinant therapeutics to circulating red blood cells |
| CN108117586A (zh) | 2010-08-10 | 2018-06-05 | 洛桑聚合联合学院 | 红细胞结合性治疗剂 |
| US9850296B2 (en) | 2010-08-10 | 2017-12-26 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| US9517257B2 (en) | 2010-08-10 | 2016-12-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| WO2014153394A1 (en) | 2013-03-21 | 2014-09-25 | Genisphere, Llc | Cellular delivery of dna intercalating agents |
| US10946079B2 (en) | 2014-02-21 | 2021-03-16 | Ecole Polytechnique Federale De Lausanne | Glycotargeting therapeutics |
| US10953101B2 (en) | 2014-02-21 | 2021-03-23 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| AU2015233084B2 (en) | 2014-02-21 | 2020-12-17 | Anokion Sa | Glycotargeting therapeutics |
| US10046056B2 (en) | 2014-02-21 | 2018-08-14 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| JP7366541B2 (ja) | 2016-02-19 | 2023-10-23 | コード バイオセラピューティクス インコーポレイテッド | 核酸キャリア及び治療上の使用方法 |
| US11253579B2 (en) | 2017-06-16 | 2022-02-22 | The University Of Chicago | Compositions and methods for inducing immune tolerance |
| CN112384239A (zh) | 2018-05-09 | 2021-02-19 | 芝加哥大学 | 影响免疫耐受的组合物和方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002515447A (ja) * | 1998-05-21 | 2002-05-28 | ザ トラスティーズ オブ ザ ユニバーシティー オブ ペンシルヴァニア | 抑制されない血管内フィブリンクロット形成の予防および治療のための組成物および方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60200169A (ja) * | 1984-03-23 | 1985-10-09 | Green Cross Corp:The | 線維素溶解酵素前駆体測定用試薬 |
-
2003
- 2003-07-01 US US10/611,723 patent/US7041287B2/en not_active Expired - Lifetime
-
2004
- 2004-06-28 JP JP2006518692A patent/JP2007521294A/ja active Pending
- 2004-06-28 EP EP04777178A patent/EP1648497A2/en not_active Withdrawn
- 2004-06-28 AU AU2004255196A patent/AU2004255196B2/en not_active Ceased
- 2004-06-28 CA CA002530529A patent/CA2530529A1/en not_active Abandoned
- 2004-06-28 WO PCT/US2004/020660 patent/WO2005004804A2/en not_active Ceased
-
2006
- 2006-02-13 US US11/352,720 patent/US20060140917A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002515447A (ja) * | 1998-05-21 | 2002-05-28 | ザ トラスティーズ オブ ザ ユニバーシティー オブ ペンシルヴァニア | 抑制されない血管内フィブリンクロット形成の予防および治療のための組成物および方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20060140917A1 (en) | 2006-06-29 |
| US20040053408A1 (en) | 2004-03-18 |
| EP1648497A2 (en) | 2006-04-26 |
| WO2005004804A2 (en) | 2005-01-20 |
| WO2005004804A3 (en) | 2005-05-12 |
| CA2530529A1 (en) | 2005-01-20 |
| AU2004255196B2 (en) | 2009-10-08 |
| AU2004255196A1 (en) | 2005-01-20 |
| US7041287B2 (en) | 2006-05-09 |
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