AU2004255196B2 - Compositions and methods for selective dissolution of nascent intravascular blood clots - Google Patents
Compositions and methods for selective dissolution of nascent intravascular blood clots Download PDFInfo
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- AU2004255196B2 AU2004255196B2 AU2004255196A AU2004255196A AU2004255196B2 AU 2004255196 B2 AU2004255196 B2 AU 2004255196B2 AU 2004255196 A AU2004255196 A AU 2004255196A AU 2004255196 A AU2004255196 A AU 2004255196A AU 2004255196 B2 AU2004255196 B2 AU 2004255196B2
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- rbc
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- clots
- biotinylated
- blood
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Classifications
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- A—HUMAN NECESSITIES
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- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/18—Erythrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Developmental Biology & Embryology (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/611,723 US7041287B2 (en) | 1998-05-21 | 2003-07-01 | Compositions and methods for selective dissolution of nascent intravascular blood clots |
| US10/611,723 | 2003-07-01 | ||
| PCT/US2004/020660 WO2005004804A2 (en) | 2003-07-01 | 2004-06-28 | Compositions and methods for selective dissolution of nascent intravascular blood clots |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2004255196A1 AU2004255196A1 (en) | 2005-01-20 |
| AU2004255196B2 true AU2004255196B2 (en) | 2009-10-08 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2004255196A Ceased AU2004255196B2 (en) | 2003-07-01 | 2004-06-28 | Compositions and methods for selective dissolution of nascent intravascular blood clots |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7041287B2 (enExample) |
| EP (1) | EP1648497A2 (enExample) |
| JP (1) | JP2007521294A (enExample) |
| AU (1) | AU2004255196B2 (enExample) |
| CA (1) | CA2530529A1 (enExample) |
| WO (1) | WO2005004804A2 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2330471A1 (en) * | 1998-05-21 | 1999-11-25 | The Trustees Of The University Of Pennsylvania | Compositions and methods for prevention and treatment of uncontrolled formation of intravascular fibrin clots |
| US7674466B2 (en) * | 1999-08-05 | 2010-03-09 | The Trustees Of The University Of Pennsylvania | Targeting and prolonging association of drugs to the luminal surface of the pulmonary vascular endothelial cells using antibodies that bind to ICAM-1 |
| AU2002241556B2 (en) * | 2000-11-01 | 2007-07-19 | Elusys Therapeutics, Inc. | Method of producing bispecific molecules by protein trans-splicing |
| US20070003552A1 (en) * | 2002-07-09 | 2007-01-04 | Gebbink Martijn F B | Cross-beta structure comprising amyloid binding proteins and methods for detection of the cross-beta structure, for modulating cross-beta structures fibril formation and for modulating cross-beta structure-mediated toxicity and method for interfering with blood coagulation |
| EP1380290A1 (en) * | 2002-07-09 | 2004-01-14 | Universitair Medisch Centrum Utrecht | Cross-beta structure pathway and its therapeutic relevance |
| WO2006073446A2 (en) * | 2004-04-28 | 2006-07-13 | The Trustees Of The University Of Pennsylvania | Peptide-mediated protein transduction into cells the hematopoietic lineage |
| WO2006050177A2 (en) * | 2004-10-29 | 2006-05-11 | The Regents Of The University Of Colorado | Antibodies that bind urokinase-type plasminogen activator and epitopes therefor |
| US20090202980A1 (en) * | 2005-03-21 | 2009-08-13 | Crossbeta Biosciences B.V. | Cross-Beta Structure Comprising Amyloid Binding Proteins and Methods for Detection of the Cross-Beta Structure, for Modulating Cross-Beta Structures Fibril Formation and for Modulating Cross-Beta Structure-Mediated Toxicity and Method for Interfering With Blood Coagulation |
| US8067187B2 (en) * | 2005-07-13 | 2011-11-29 | Crossbeta Biosciences B.V. | Cross-β structure binding compounds |
| CA2615078A1 (en) * | 2005-07-13 | 2007-01-18 | Crossbeta Biosciences B.V. | Methods for determining the effect of a treatment on the cross-.beta. structure content of a protein; selection of treatments and uses thereof |
| US8114832B2 (en) * | 2005-07-13 | 2012-02-14 | Crossbeta Biosciences B.V. | Method for detecting and/or removing a protein comprising a cross-beta structure from a pharmaceutical composition |
| US20090130104A1 (en) * | 2005-10-05 | 2009-05-21 | The Trustees Of The University Of Pennsylvania | Fusion proteins for inhibition and dissolution of coagulation |
| EP2007800A1 (en) * | 2006-03-17 | 2008-12-31 | Crossbeta Biosciences B.V. | Methods of binding of cross-beta structures by chaperones |
| EP3351270A1 (en) * | 2007-05-23 | 2018-07-25 | The Trustees of the University of Pennsylvania | Targeted carriers for intracellular drug delivery |
| EP2058000A1 (en) * | 2007-11-08 | 2009-05-13 | Crossbeta Biosciences B.V. | Immunogenic compositions capable of activating T cells |
| EP2058001A1 (en) * | 2007-11-08 | 2009-05-13 | Crossbeta Biosciences B.V. | Enhancement of immunogenicity of antigens |
| WO2009086552A1 (en) * | 2008-01-02 | 2009-07-09 | The Trustees Of The University Of Pennsylvania | Targeting recombinant therapeutics to circulating red blood cells |
| US9850296B2 (en) | 2010-08-10 | 2017-12-26 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| US9517257B2 (en) | 2010-08-10 | 2016-12-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| US9518087B2 (en) | 2010-08-10 | 2016-12-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| WO2014153394A1 (en) | 2013-03-21 | 2014-09-25 | Genisphere, Llc | Cellular delivery of dna intercalating agents |
| US10046056B2 (en) | 2014-02-21 | 2018-08-14 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| US10953101B2 (en) | 2014-02-21 | 2021-03-23 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| US10946079B2 (en) | 2014-02-21 | 2021-03-16 | Ecole Polytechnique Federale De Lausanne | Glycotargeting therapeutics |
| CN106456743A (zh) | 2014-02-21 | 2017-02-22 | 洛桑聚合联合学院 | 糖靶向性治疗剂 |
| AU2017220012B2 (en) | 2016-02-19 | 2024-05-02 | Code Biotherapeutics, Inc. | Nucleic acid carriers and therapeutic methods of use |
| EP3638296A1 (en) | 2017-06-16 | 2020-04-22 | The University Of Chicago | Compositions and methods for inducing immune tolerance |
| KR20210010879A (ko) | 2018-05-09 | 2021-01-28 | 더 유니버서티 오브 시카고 | 면역 관용 관여 조성물 및 방법 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60200169A (ja) * | 1984-03-23 | 1985-10-09 | Green Cross Corp:The | 線維素溶解酵素前駆体測定用試薬 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2330471A1 (en) * | 1998-05-21 | 1999-11-25 | The Trustees Of The University Of Pennsylvania | Compositions and methods for prevention and treatment of uncontrolled formation of intravascular fibrin clots |
-
2003
- 2003-07-01 US US10/611,723 patent/US7041287B2/en not_active Expired - Lifetime
-
2004
- 2004-06-28 EP EP04777178A patent/EP1648497A2/en not_active Withdrawn
- 2004-06-28 CA CA002530529A patent/CA2530529A1/en not_active Abandoned
- 2004-06-28 JP JP2006518692A patent/JP2007521294A/ja active Pending
- 2004-06-28 AU AU2004255196A patent/AU2004255196B2/en not_active Ceased
- 2004-06-28 WO PCT/US2004/020660 patent/WO2005004804A2/en not_active Ceased
-
2006
- 2006-02-13 US US11/352,720 patent/US20060140917A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60200169A (ja) * | 1984-03-23 | 1985-10-09 | Green Cross Corp:The | 線維素溶解酵素前駆体測定用試薬 |
Non-Patent Citations (6)
| Title |
|---|
| Heeremans J.L.M et al. Journal of Drug Targeting, 1995, Vol. 3, Pages 301-310 * |
| Kaijihara J et al. Biochimica et Biophysica Acta, 1994, Vol. 1199, Pages 202-208 * |
| Muzykantov V.R & Taylor R.P. Analytical Biochemistry, 1994, Vol. 223, Pages 142-148. * |
| Muzykantov V.R et al. Analytical Biochemistry, 1996, Vol. 241, Pages 109-119 * |
| Muzykantov V.R et al. Biochimica Biophysica Acta, 1986, Vol. 884, No. 2, Pages 355-362 * |
| Muzykantov V.R et al. FEBS Letters, 1985, Vol. 182, No. 1, Pages 62-66 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1648497A2 (en) | 2006-04-26 |
| JP2007521294A (ja) | 2007-08-02 |
| CA2530529A1 (en) | 2005-01-20 |
| WO2005004804A3 (en) | 2005-05-12 |
| US7041287B2 (en) | 2006-05-09 |
| WO2005004804A2 (en) | 2005-01-20 |
| AU2004255196A1 (en) | 2005-01-20 |
| US20060140917A1 (en) | 2006-06-29 |
| US20040053408A1 (en) | 2004-03-18 |
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| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |