JP2007521015A5 - - Google Patents
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- Publication number
- JP2007521015A5 JP2007521015A5 JP2006526617A JP2006526617A JP2007521015A5 JP 2007521015 A5 JP2007521015 A5 JP 2007521015A5 JP 2006526617 A JP2006526617 A JP 2006526617A JP 2006526617 A JP2006526617 A JP 2006526617A JP 2007521015 A5 JP2007521015 A5 JP 2007521015A5
- Authority
- JP
- Japan
- Prior art keywords
- immunogenic membrane
- pharmaceutical composition
- subject
- cancer
- membrane protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 27
- 230000002163 immunogen Effects 0.000 claims 20
- 206010028980 Neoplasm Diseases 0.000 claims 15
- 108010052285 Membrane Proteins Proteins 0.000 claims 14
- 108090000765 processed proteins & peptides Proteins 0.000 claims 14
- 102000004196 processed proteins & peptides Human genes 0.000 claims 13
- 201000011510 cancer Diseases 0.000 claims 12
- 230000001419 dependent effect Effects 0.000 claims 12
- 150000003431 steroids Chemical class 0.000 claims 12
- 102000018697 Membrane Proteins Human genes 0.000 claims 11
- 210000004027 cell Anatomy 0.000 claims 11
- 239000008194 pharmaceutical composition Substances 0.000 claims 11
- 108091033319 polynucleotide Proteins 0.000 claims 11
- 102000040430 polynucleotide Human genes 0.000 claims 11
- 239000002157 polynucleotide Substances 0.000 claims 11
- 229920001184 polypeptide Polymers 0.000 claims 11
- 239000012634 fragment Substances 0.000 claims 10
- 150000001875 compounds Chemical class 0.000 claims 8
- 239000003814 drug Substances 0.000 claims 8
- 238000012360 testing method Methods 0.000 claims 8
- 102100034452 Alternative prion protein Human genes 0.000 claims 7
- 102100038002 Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit STT3A Human genes 0.000 claims 7
- 102100035913 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Human genes 0.000 claims 7
- 101000924727 Homo sapiens Alternative prion protein Proteins 0.000 claims 7
- 101000952934 Homo sapiens Atrial natriuretic peptide-converting enzyme Proteins 0.000 claims 7
- 101000661592 Homo sapiens Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit STT3A Proteins 0.000 claims 7
- 101001073261 Homo sapiens Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Proteins 0.000 claims 7
- 101001050468 Homo sapiens Integral membrane protein 2B Proteins 0.000 claims 7
- 101001043598 Homo sapiens Low-density lipoprotein receptor-related protein 4 Proteins 0.000 claims 7
- 101000573901 Homo sapiens Major prion protein Proteins 0.000 claims 7
- 101001003205 Homo sapiens Methylosome subunit pICln Proteins 0.000 claims 7
- 101000591211 Homo sapiens Receptor-type tyrosine-protein phosphatase O Proteins 0.000 claims 7
- 101000831927 Homo sapiens Stomatin-like protein 2, mitochondrial Proteins 0.000 claims 7
- 101000695537 Homo sapiens Synaptophysin-like protein 1 Proteins 0.000 claims 7
- 101000613001 Homo sapiens Tetraspanin-6 Proteins 0.000 claims 7
- 101000831496 Homo sapiens Toll-like receptor 3 Proteins 0.000 claims 7
- 101000798727 Homo sapiens Transmembrane 9 superfamily member 2 Proteins 0.000 claims 7
- 102100023350 Integral membrane protein 2B Human genes 0.000 claims 7
- 102100021918 Low-density lipoprotein receptor-related protein 4 Human genes 0.000 claims 7
- 102100020846 Methylosome subunit pICln Human genes 0.000 claims 7
- 102100028646 Nociceptin receptor Human genes 0.000 claims 7
- -1 RAGA Proteins 0.000 claims 7
- 102100025001 Ras-related GTP-binding protein A Human genes 0.000 claims 7
- 102100025234 Receptor of activated protein C kinase 1 Human genes 0.000 claims 7
- 102100034086 Receptor-type tyrosine-protein phosphatase O Human genes 0.000 claims 7
- 108010044157 Receptors for Activated C Kinase Proteins 0.000 claims 7
- 102100024172 Stomatin-like protein 2, mitochondrial Human genes 0.000 claims 7
- 102100028532 Synaptophysin-like protein 1 Human genes 0.000 claims 7
- 102100040869 Tetraspanin-6 Human genes 0.000 claims 7
- 102100024324 Toll-like receptor 3 Human genes 0.000 claims 7
- 102100032503 Transmembrane 9 superfamily member 2 Human genes 0.000 claims 7
- 230000000692 anti-sense effect Effects 0.000 claims 7
- 239000003795 chemical substances by application Substances 0.000 claims 7
- 239000012528 membrane Substances 0.000 claims 7
- 108010020615 nociceptin receptor Proteins 0.000 claims 7
- 229940124597 therapeutic agent Drugs 0.000 claims 7
- 101000976442 Homo sapiens Zona pellucida sperm-binding protein 3 Proteins 0.000 claims 6
- 102100023634 Zona pellucida sperm-binding protein 3 Human genes 0.000 claims 6
- 230000003993 interaction Effects 0.000 claims 6
- 230000009870 specific binding Effects 0.000 claims 5
- 230000004071 biological effect Effects 0.000 claims 4
- 230000002159 abnormal effect Effects 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 230000001225 therapeutic effect Effects 0.000 claims 3
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 2
- 108060003951 Immunoglobulin Proteins 0.000 claims 2
- 208000000453 Skin Neoplasms Diseases 0.000 claims 2
- 239000000556 agonist Substances 0.000 claims 2
- 239000005557 antagonist Substances 0.000 claims 2
- 102000018358 immunoglobulin Human genes 0.000 claims 2
- 229940072221 immunoglobulins Drugs 0.000 claims 2
- 108020004999 messenger RNA Proteins 0.000 claims 2
- 239000008177 pharmaceutical agent Substances 0.000 claims 2
- 238000012216 screening Methods 0.000 claims 2
- 201000000849 skin cancer Diseases 0.000 claims 2
- 239000013603 viral vector Substances 0.000 claims 2
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 1
- 229930182558 Sterol Natural products 0.000 claims 1
- 241000700618 Vaccinia virus Species 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 230000027455 binding Effects 0.000 claims 1
- 210000000481 breast Anatomy 0.000 claims 1
- 230000030833 cell death Effects 0.000 claims 1
- 210000003679 cervix uteri Anatomy 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 230000004069 differentiation Effects 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 210000004696 endometrium Anatomy 0.000 claims 1
- 210000000981 epithelium Anatomy 0.000 claims 1
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 201000001441 melanoma Diseases 0.000 claims 1
- 210000005170 neoplastic cell Anatomy 0.000 claims 1
- 210000001672 ovary Anatomy 0.000 claims 1
- 210000002307 prostate Anatomy 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
- 229940126586 small molecule drug Drugs 0.000 claims 1
- 150000003384 small molecules Chemical class 0.000 claims 1
- 150000003432 sterols Chemical group 0.000 claims 1
- 235000003702 sterols Nutrition 0.000 claims 1
- 238000013518 transcription Methods 0.000 claims 1
- 230000035897 transcription Effects 0.000 claims 1
- 238000013519 translation Methods 0.000 claims 1
- 241000701161 unidentified adenovirus Species 0.000 claims 1
- 241001430294 unidentified retrovirus Species 0.000 claims 1
- 210000003932 urinary bladder Anatomy 0.000 claims 1
- 238000002255 vaccination Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03090307 | 2003-09-18 | ||
| US51207803P | 2003-10-20 | 2003-10-20 | |
| PCT/EP2004/010780 WO2005026735A2 (en) | 2003-09-18 | 2004-09-20 | Differentially expressed tumour-specific polypeptides for use in the diagnosis and treatment of cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007521015A JP2007521015A (ja) | 2007-08-02 |
| JP2007521015A5 true JP2007521015A5 (enExample) | 2007-11-08 |
Family
ID=37657558
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006526617A Pending JP2007521015A (ja) | 2003-09-18 | 2004-09-20 | 癌の診断及び治療に用いられる示差的に発現する腫瘍特異的ポリペプチド |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20090252721A1 (enExample) |
| EP (2) | EP2050827A3 (enExample) |
| JP (1) | JP2007521015A (enExample) |
| CN (1) | CN1902326A (enExample) |
| AU (1) | AU2004272747A1 (enExample) |
| BR (1) | BRPI0414446A (enExample) |
| CA (1) | CA2539490A1 (enExample) |
| IL (1) | IL174047A0 (enExample) |
| SG (1) | SG146622A1 (enExample) |
| WO (1) | WO2005026735A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2599875A1 (en) * | 2005-03-03 | 2006-09-08 | Takeda Pharmaceutical Company Limited | Preventive/therapeutic agent for cancer |
| US7897583B2 (en) | 2005-05-24 | 2011-03-01 | Isis Pharmaceuticals, Inc. | Compositions and their uses directed to PTPRU |
| CN101365473B (zh) | 2005-11-16 | 2013-04-03 | 潘塔希生物科学股份有限公司 | 用于治疗或预防卵巢癌的药物组合物 |
| JP2010526766A (ja) * | 2007-02-02 | 2010-08-05 | ノバルティス アーゲー | 骨関連障害を処置するためのスクレロスチン結合パートナーのモジュレーター |
| WO2008147956A2 (en) * | 2007-05-25 | 2008-12-04 | Centocor, Inc. | Toll-like receptor 3 modulators and uses thereof |
| CN102395682B (zh) * | 2007-09-06 | 2015-09-30 | 生物治疗诊断股份有限公司 | 肿瘤分级和癌症预后 |
| US8158373B2 (en) * | 2008-03-25 | 2012-04-17 | Case Western Reserve University | Method of detecting cancer and evaluating cancer prognosis |
| WO2010056993A2 (en) * | 2008-11-14 | 2010-05-20 | Emory University | Prostate cancer biomarkers to predict recurrence and metastatic potential |
| WO2010075521A1 (en) * | 2008-12-23 | 2010-07-01 | Case Western Reserve University | Compositions and methods of treating cancer |
| US8940826B2 (en) | 2009-07-16 | 2015-01-27 | Omnova Solutions Inc. | Protective coating compositions |
| EA201390370A1 (ru) | 2010-09-15 | 2013-07-30 | Олмак Дайэгностикс Лимитед | Молекулярно-диагностический тест для определения онкологического заболевания |
| US20150301068A1 (en) | 2012-01-30 | 2015-10-22 | Vib Vzw | Means and method for diagnosis and treatment of alzheimer's disease |
| CN107267554A (zh) * | 2012-03-14 | 2017-10-20 | 萨克生物研究学院 | 腺病毒肿瘤诊断法 |
| JP6327662B2 (ja) * | 2012-09-26 | 2018-05-23 | 学校法人藤田学園 | 細胞表面タンパクを抗原とする抗体を測定する方法 |
| WO2016080830A2 (en) * | 2014-11-18 | 2016-05-26 | Pantarhei Bioscience B.V. | Immunotherapeutic method for treating pancreatic cancer |
| CN109646685A (zh) * | 2017-10-12 | 2019-04-19 | 北京医院 | stomatin蛋白及其编码基因在肺癌诊断治疗中的应用 |
| CN111394370B (zh) * | 2020-03-03 | 2022-03-25 | 华南农业大学 | 一种猪RagA基因及其应用 |
| CA3172489A1 (en) | 2020-03-23 | 2021-09-30 | Amit KHANDHAR | Nanoemulsion compositions and methods for delivery of nra |
| CN114540349B (zh) * | 2020-11-27 | 2024-11-22 | 中国科学院分子细胞科学卓越创新中心 | 结合yb-1蛋白的核酸分子 |
| CA3232658A1 (en) | 2021-09-22 | 2023-03-30 | Steven Gregory REED | Rna vaccines against infectious diseases |
| EP4404957A4 (en) | 2021-09-22 | 2025-08-06 | Hdt Bio Corp | CANCER THERAPY COMPOSITIONS AND THEIR USES |
| WO2023048759A1 (en) | 2021-09-22 | 2023-03-30 | Hdt Bio Corp. | Sars-cov-2 rna vaccine compositions and methods of use |
| EP4404919A4 (en) | 2021-09-22 | 2025-08-20 | Hdt Bio Corp | DRIED NANOPARTICLE COMPOSITIONS |
| CN116482367A (zh) * | 2023-05-04 | 2023-07-25 | 中国中医科学院望京医院(中国中医科学院骨伤科研究所) | 一种联合mSEPT9检测和生物标志物的结直肠癌检测方法 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0003415A3 (en) | 1978-01-20 | 1979-08-22 | Glaxo Group Limited | Beta-lactam compounds, processes for their preparation,compositions containing them and intermediates of use in their preparation |
| US4849338A (en) | 1982-07-16 | 1989-07-18 | Syntex (U.S.A.) Inc. | Simultaneous calibration heterogeneous immunoassay |
| US4843000A (en) | 1979-12-26 | 1989-06-27 | Syntex (U.S.A.) Inc. | Simultaneous calibration heterogeneous immunoassay |
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| US4520110A (en) | 1981-10-06 | 1985-05-28 | The Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing a phycobiliprotein labeled ligand or receptor |
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4542104A (en) | 1983-04-06 | 1985-09-17 | The Board Of Trustees Of The Leland Stanford Jr. Univ. | Phycobiliprotein fluorescent conjugates |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5185444A (en) | 1985-03-15 | 1993-02-09 | Anti-Gene Deveopment Group | Uncharged morpolino-based polymers having phosphorous containing chiral intersubunit linkages |
| US5217866A (en) | 1985-03-15 | 1993-06-08 | Anti-Gene Development Group | Polynucleotide assay reagent and method |
| US4902505A (en) | 1986-07-30 | 1990-02-20 | Alkermes | Chimeric peptides for neuropeptide delivery through the blood-brain barrier |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US4904582A (en) | 1987-06-11 | 1990-02-27 | Synthetic Genetics | Novel amphiphilic nucleic acid conjugates |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| GB9705949D0 (en) | 1997-03-21 | 1997-05-07 | Electrophoretics International | Diagnosis of tumours and other abnormalities of body cells |
| US6197543B1 (en) * | 1997-10-28 | 2001-03-06 | Incyte Pharmaceuticals, Inc. | Human vesicle membrane protein-like proteins |
| US6902898B2 (en) * | 1998-11-16 | 2005-06-07 | National Institute Of Advanced Industrial Science And Technology | Human derived bradeion proteins, DNA coding for the proteins, and uses thereof |
| EP1033404A1 (en) * | 1999-01-29 | 2000-09-06 | F. Hoffmann-La Roche Ag | New gene with down-regulated expression in metastatic human melanoma cells |
| US6228392B1 (en) | 1999-04-29 | 2001-05-08 | Gene Tools, Llc | Osmotic delivery composition, solution, and method |
| WO2001022920A2 (en) * | 1999-09-29 | 2001-04-05 | Human Genome Sciences, Inc. | Colon and colon cancer associated polynucleotides and polypeptides |
| US20030104413A1 (en) * | 2000-07-14 | 2003-06-05 | Tang Y. Tom | Novel Nucleic acids and polypeptides |
| US20030108926A1 (en) * | 2000-03-15 | 2003-06-12 | Eos Biotechnology, Inc. | Novel methods of diagnosing colorectal cancer, compositions, and methods of screening for colorectal cancer modulators |
| AU2001269766A1 (en) * | 2000-06-09 | 2001-12-24 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of colon cancer |
| JP2004512029A (ja) * | 2000-08-16 | 2004-04-22 | カイロン コーポレイション | ヒト遺伝子および遺伝子発現産物 |
| US20030134283A1 (en) * | 2000-10-03 | 2003-07-17 | Peterson David P. | Genes regulated in dendritic cell differentiation |
| US20020160382A1 (en) * | 2000-10-11 | 2002-10-31 | Lasek Amy W. | Genes expressed in colon cancer |
| EP1444361A4 (en) * | 2001-09-28 | 2006-12-27 | Whitehead Biomedical Inst | CLASSIFICATION OF PULMONARY CARCINOMAS BY ANALYSIS OF GENE EXPRESSION |
| EP1308459A3 (en) * | 2001-11-05 | 2003-07-09 | Research Association for Biotechnology | Full-length cDNA sequences |
| JP2006515318A (ja) * | 2002-10-29 | 2006-05-25 | ファルマシア・コーポレーション | 特異的に発現する癌関連遺伝子、それによってコードされるポリペプチドおよびその使用方法 |
-
2004
- 2004-09-20 US US10/571,167 patent/US20090252721A1/en not_active Abandoned
- 2004-09-20 EP EP08163922A patent/EP2050827A3/en not_active Withdrawn
- 2004-09-20 EP EP04765615A patent/EP1673470A2/en not_active Ceased
- 2004-09-20 JP JP2006526617A patent/JP2007521015A/ja active Pending
- 2004-09-20 AU AU2004272747A patent/AU2004272747A1/en not_active Abandoned
- 2004-09-20 CN CNA200480034085XA patent/CN1902326A/zh active Pending
- 2004-09-20 BR BRPI0414446-5A patent/BRPI0414446A/pt not_active IP Right Cessation
- 2004-09-20 WO PCT/EP2004/010780 patent/WO2005026735A2/en not_active Ceased
- 2004-09-20 CA CA002539490A patent/CA2539490A1/en not_active Abandoned
- 2004-09-20 SG SG200806620-1A patent/SG146622A1/en unknown
-
2006
- 2006-03-01 IL IL174047A patent/IL174047A0/en unknown
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