JP2007518424A5 - - Google Patents
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- Publication number
- JP2007518424A5 JP2007518424A5 JP2006551422A JP2006551422A JP2007518424A5 JP 2007518424 A5 JP2007518424 A5 JP 2007518424A5 JP 2006551422 A JP2006551422 A JP 2006551422A JP 2006551422 A JP2006551422 A JP 2006551422A JP 2007518424 A5 JP2007518424 A5 JP 2007518424A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleotide
- buffer
- nucleotide triphosphate
- replacing
- treating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002773 nucleotide Substances 0.000 claims 3
- 125000003729 nucleotide group Chemical group 0.000 claims 3
- 239000001226 triphosphate Substances 0.000 claims 2
- 235000011178 triphosphate Nutrition 0.000 claims 2
- UNXRWKVEANCORM-UHFFFAOYSA-I triphosphate(5-) Chemical compound [O-]P([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O UNXRWKVEANCORM-UHFFFAOYSA-I 0.000 claims 2
- XPPKVPWEQAFLFU-UHFFFAOYSA-J Pyrophosphate Chemical compound [O-]P([O-])(=O)OP([O-])([O-])=O XPPKVPWEQAFLFU-UHFFFAOYSA-J 0.000 claims 1
- 230000003321 amplification Effects 0.000 claims 1
- 239000001177 diphosphate Substances 0.000 claims 1
- 235000011180 diphosphates Nutrition 0.000 claims 1
- 238000003199 nucleic acid amplification method Methods 0.000 claims 1
Claims (1)
- ヌクレオチド三リン酸を含む緩衝液を利用する増幅反応を実施するための方法であって、緩衝液を処理し、ヌクレオチド三リン酸の一部をヌクレオチド二リン酸で置き換えることを含む方法。
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53881604P | 2004-01-23 | 2004-01-23 | |
US53881404P | 2004-01-23 | 2004-01-23 | |
US53881504P | 2004-01-23 | 2004-01-23 | |
US60/538,816 | 2004-01-23 | ||
US60/538,815 | 2004-01-23 | ||
US60/538,814 | 2004-01-23 | ||
PCT/US2005/002414 WO2005070027A2 (en) | 2004-01-23 | 2005-01-21 | A novel nucleotide mixture for improved nucleic acid amplification performance |
Publications (4)
Publication Number | Publication Date |
---|---|
JP2007518424A JP2007518424A (ja) | 2007-07-12 |
JP2007518424A6 JP2007518424A6 (ja) | 2007-10-11 |
JP2007518424A5 true JP2007518424A5 (ja) | 2008-03-06 |
JP4866248B2 JP4866248B2 (ja) | 2012-02-01 |
Family
ID=34812082
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006551423A Pending JP2007518425A (ja) | 2004-01-23 | 2005-01-21 | Hcv3’非翻訳領域を効率的に増幅および検出するためのプライマーおよびプローブの設計 |
JP2006551422A Expired - Fee Related JP4866248B2 (ja) | 2004-01-23 | 2005-01-21 | 核酸増幅性能改良のための新規ヌクレオチド混合物 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006551423A Pending JP2007518425A (ja) | 2004-01-23 | 2005-01-21 | Hcv3’非翻訳領域を効率的に増幅および検出するためのプライマーおよびプローブの設計 |
Country Status (6)
Country | Link |
---|---|
US (3) | US7364854B2 (ja) |
EP (3) | EP2042612B1 (ja) |
JP (2) | JP2007518425A (ja) |
AT (3) | ATE491810T1 (ja) |
DE (3) | DE602005025424D1 (ja) |
WO (2) | WO2005070027A2 (ja) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2147118A4 (en) * | 2007-04-27 | 2010-09-01 | Eragen Biosciences Inc | MATERIALS AND METHOD FOR DETECTING HEPATITIS C VIRUS |
JP2009284896A (ja) * | 2007-07-26 | 2009-12-10 | Fujifilm Corp | 核酸増幅方法 |
US20090162856A1 (en) * | 2007-11-06 | 2009-06-25 | Hayato Miyoshi | Rna detection method |
JP2012513757A (ja) * | 2008-12-31 | 2012-06-21 | アボット・ラボラトリーズ | C型肝炎ウイルスの検出用プライマー及びプローブ |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09107970A (ja) * | 1995-10-17 | 1997-04-28 | Soyaku Gijutsu Kenkyusho:Kk | C型肝炎ウイルス由来核酸、該核酸を用いたウイルスの検出方法 |
DE3164463D1 (en) * | 1980-11-12 | 1984-08-02 | Mitsubishi Chem Ind | Glutamine derivatives usable for curing immune diseases, methods for their preparation and compositions comprising said derivatives |
US5087565A (en) * | 1984-07-02 | 1992-02-11 | Du Pont Merck Pharmaceutical Company | Synthetic process for preparation of 32 P-labeled nucleotides |
DE3689223T2 (de) | 1985-05-15 | 1994-03-03 | Amoco Corp | Cytidinanaloga. |
US4876187A (en) | 1985-12-05 | 1989-10-24 | Meiogenics, Inc. | Nucleic acid compositions with scissile linkage useful for detecting nucleic acid sequences |
US5032511A (en) * | 1987-03-31 | 1991-07-16 | Mitsubishi Kasei Corporation | DNA fragments coding for antigens specific to non-A non-B hepatitis, expression vectors containing said DNA fragments, transformants and process for producing said antigens |
CA1340843C (en) | 1987-07-31 | 1999-12-07 | J. Lawrence Burg | Selective amplification of target polynucleotide sequences |
US5698390A (en) * | 1987-11-18 | 1997-12-16 | Chiron Corporation | Hepatitis C immunoassays |
US5714596A (en) * | 1987-11-18 | 1998-02-03 | Chiron Corporation | NANBV diagnostics: polynucleotides useful for screening for hepatitis C virus |
US5712088A (en) * | 1987-11-18 | 1998-01-27 | Chiron Corporation | Methods for detecting Hepatitis C virus using polynucleotides specific for same |
US5030557A (en) | 1987-11-24 | 1991-07-09 | Ml Technology Venture | Means and method for enhancing nucleic acid hybridization |
JP2650159B2 (ja) | 1988-02-24 | 1997-09-03 | アクゾ・ノベル・エヌ・ベー | 核酸増幅方法 |
CA2020958C (en) | 1989-07-11 | 2005-01-11 | Daniel L. Kacian | Nucleic acid sequence amplification methods |
AU627931B2 (en) | 1989-09-18 | 1992-09-03 | Canon Kabushiki Kaisha | Ink jet recording head and ink jet recording apparatus having same |
DE69131891T2 (de) * | 1990-02-16 | 2000-06-15 | Hoffmann La Roche | Verbesserungen in der spezifität und zweckmässigkeit der polymerase-kettenreaktion |
CA2135073C (en) | 1992-05-06 | 2002-11-19 | Daniel L. Kacian | Nucleic acid sequence amplification method, composition and kit |
US5648232A (en) * | 1993-01-21 | 1997-07-15 | The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland | Microbiological best method and reagents |
KR100238833B1 (ko) * | 1994-03-10 | 2000-03-02 | 다니엘 엘. 캐시앙 | 이온성 세제에 의한 효소 개재 반응의 억제를 방지하는 방법 |
US5874565A (en) * | 1995-08-29 | 1999-02-23 | Washington University | Nucleic acids comprising a highly conserved novel 3 terminal sequence element of the hepatitis C virus |
US6127116A (en) * | 1995-08-29 | 2000-10-03 | Washington University | Functional DNA clone for hepatitis C virus (HCV) and uses thereof |
DE19612779A1 (de) * | 1996-03-29 | 1997-10-02 | Boehringer Mannheim Gmbh | Verfahren zur spezifischen Vervielfältigung von langen Nukleinsäuren durch PCR |
WO1998006736A1 (en) * | 1996-08-14 | 1998-02-19 | Life Technologies, Inc. | Stable compositions for nucleic acid amplification and sequencing |
DE19647055A1 (de) * | 1996-11-14 | 1998-05-20 | Boehringer Mannheim Gmbh | Stabilisierte wässrige Nukleosidtriphosphat-Lösungen |
ATE486961T1 (de) * | 1997-04-03 | 2010-11-15 | Life Technologies Corp | Verfahren und produkte zur reversen transkription gekoppelt mit polymerasekettenreaktion (rt-pcr) |
ZA989950B (en) | 1997-11-17 | 1999-05-04 | Akzo Nobel Nv | Transcription based amplification of double stranded DNA targets |
WO1999055847A2 (en) * | 1998-04-27 | 1999-11-04 | Ribozyme Pharmaceuticals, Inc. | Enzymatic nucleic acids molecules which modulate the expressions and/or replication of hepatitis c virus |
WO2000000638A2 (en) * | 1998-06-26 | 2000-01-06 | Akzo Nobel N.V. | Tagging of rna amplicons generated by transcription-based amplification |
US6638714B1 (en) * | 1999-02-03 | 2003-10-28 | Ortho-Clinical Diagnostics, Inc. | Oligonucleotide primers for efficient detection of hepatitis C virus (HCV) and methods of use thereof |
US6300075B1 (en) * | 1999-02-03 | 2001-10-09 | Ortho-Clinical Diagnostics, Inc | Enhancement of the specificity of nucleic acid amplification by carrier nucleic acid |
AU5322800A (en) * | 1999-06-04 | 2000-12-28 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Cloned genone of infectious hepatitis c virus of genotype 2a and uses thereof |
US6271004B1 (en) * | 1999-06-25 | 2001-08-07 | Display Systems Biotech A/S | Method for improved reverse transcription at high temperatures |
EP1233976A4 (en) * | 1999-11-17 | 2003-06-11 | Jiuping Ji | SIMULTANEOUS DETECTION OF HBV, HCV AND HIV IN PLASMA SAMPLES WITH THE AID OF A MULTIPLEX FIXING TEST |
WO2001064959A1 (en) * | 2000-03-02 | 2001-09-07 | Akzo Nobel N.V. | Detection of hepatitis b virus rna |
EP1383782A1 (en) * | 2001-03-26 | 2004-01-28 | Sirna Therpeutics, Inc. | Oligonucleotide mediated inhibition of hepatitis b virus and hepatitis c virus replication |
WO2003016572A1 (en) * | 2001-08-17 | 2003-02-27 | Eli Lilly And Company | Oligonucleotide therapeutics for treating hepatitis c virus infections |
US6783940B2 (en) * | 2001-10-31 | 2004-08-31 | Applera Corporation | Method of reducing non-specific amplification in PCR |
US6750009B2 (en) * | 2002-01-29 | 2004-06-15 | Apath, Llc | Multiple viral replicon culture systems |
WO2003100014A2 (en) * | 2002-05-24 | 2003-12-04 | Smithkline Beecham Corporation | Method for quantitating negative strand rna synthesis |
-
2005
- 2005-01-21 AT AT08075840T patent/ATE491810T1/de not_active IP Right Cessation
- 2005-01-21 DE DE602005025424T patent/DE602005025424D1/de active Active
- 2005-01-21 DE DE602005011754T patent/DE602005011754D1/de active Active
- 2005-01-21 AT AT05722543T patent/ATE417938T1/de not_active IP Right Cessation
- 2005-01-21 WO PCT/US2005/002414 patent/WO2005070027A2/en not_active Application Discontinuation
- 2005-01-21 WO PCT/US2005/002415 patent/WO2005071117A2/en not_active Application Discontinuation
- 2005-01-21 EP EP08075840A patent/EP2042612B1/en not_active Not-in-force
- 2005-01-21 JP JP2006551423A patent/JP2007518425A/ja active Pending
- 2005-01-21 US US11/040,371 patent/US7364854B2/en active Active
- 2005-01-21 AT AT05712046T patent/ATE481507T1/de not_active IP Right Cessation
- 2005-01-21 JP JP2006551422A patent/JP4866248B2/ja not_active Expired - Fee Related
- 2005-01-21 DE DE602005023586T patent/DE602005023586D1/de active Active
- 2005-01-21 EP EP05712046A patent/EP1721015B1/en not_active Not-in-force
- 2005-01-21 US US11/040,417 patent/US20060003343A1/en not_active Abandoned
- 2005-01-21 EP EP05722543A patent/EP1706512B1/en not_active Not-in-force
-
2008
- 2008-02-11 US US12/069,606 patent/US7670779B2/en not_active Expired - Fee Related
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