JP2007516426A5 - - Google Patents
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- JP2007516426A5 JP2007516426A5 JP2006533143A JP2006533143A JP2007516426A5 JP 2007516426 A5 JP2007516426 A5 JP 2007516426A5 JP 2006533143 A JP2006533143 A JP 2006533143A JP 2006533143 A JP2006533143 A JP 2006533143A JP 2007516426 A5 JP2007516426 A5 JP 2007516426A5
- Authority
- JP
- Japan
- Prior art keywords
- dna
- complementary target
- probes
- probe
- minutes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000523 sample Substances 0.000 description 14
- 230000000295 complement effect Effects 0.000 description 12
- 238000001514 detection method Methods 0.000 description 4
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 239000007853 buffer solution Substances 0.000 description 3
- PYWVYCXTNDRMGF-UHFFFAOYSA-N rhodamine B Chemical compound [Cl-].C=12C=CC(=[N+](CC)CC)C=C2OC2=CC(N(CC)CC)=CC=C2C=1C1=CC=CC=C1C(O)=O PYWVYCXTNDRMGF-UHFFFAOYSA-N 0.000 description 3
- 239000012266 salt solution Substances 0.000 description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 108091034117 Oligonucleotide Proteins 0.000 description 1
- 238000000137 annealing Methods 0.000 description 1
- 229920001222 biopolymer Polymers 0.000 description 1
- 239000002299 complementary DNA Substances 0.000 description 1
- 238000004925 denaturation Methods 0.000 description 1
- 230000036425 denaturation Effects 0.000 description 1
- 238000010494 dissociation reaction Methods 0.000 description 1
- 230000005593 dissociations Effects 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
- 102000054765 polymorphisms of proteins Human genes 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000000527 sonication Methods 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47125703P | 2003-05-16 | 2003-05-16 | |
| US55279304P | 2004-03-12 | 2004-03-12 | |
| PCT/US2004/015413 WO2004111602A2 (en) | 2003-05-16 | 2004-05-17 | Colorimetric and fluorescent methods for sensing of oligonucleotides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007516426A JP2007516426A (ja) | 2007-06-21 |
| JP2007516426A5 true JP2007516426A5 (https=) | 2007-08-02 |
Family
ID=33555305
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006533143A Pending JP2007516426A (ja) | 2003-05-16 | 2004-05-17 | オリゴヌクレオチドの検出のための比色法および蛍光法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20050059042A1 (https=) |
| EP (1) | EP1634050A4 (https=) |
| JP (1) | JP2007516426A (https=) |
| WO (1) | WO2004111602A2 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005107404A2 (en) * | 2004-05-03 | 2005-11-17 | The Penn State Research Foundation | Methods and systems for nanoparticle enhancement of signals |
| US20080286880A1 (en) * | 2004-07-07 | 2008-11-20 | The Penn State Research Foundation | Methods and Systems for Nanoparticle Enhancement of Signals |
| EP1848823A4 (en) * | 2005-01-21 | 2008-06-25 | Univ Rochester | METHOD FOR SEPARATING SHORT INDIVIDUAL STRUCTURAL NUCLEIC ACID OF LONG SINGLE AND DOUBLE STRANDUCLEIC ACID AND ASSOCIATED BIOMOLECULAR TESTS |
| US20090221095A1 (en) * | 2005-10-13 | 2009-09-03 | Northwestern University | Colorimetric Screening of DNA Binding/Intercalating Agents with Gold Nanoparticle Probes |
| US8057989B2 (en) * | 2006-02-10 | 2011-11-15 | The University Of Hong Kong | Label-free optical sensing and characterization of biomolecules by d8 or d10 metal complexes |
| US8309304B2 (en) | 2006-02-10 | 2012-11-13 | The University Of Hong Kong | Label-free optical sensing and characterization of biomolecules by d8 or d10 metal complexes |
| KR100828936B1 (ko) * | 2006-08-01 | 2008-05-20 | 김성천 | 단일가닥핵산 압타머와 금-나노입자를 이용한 생체분자분석방법 |
| US20090130746A1 (en) * | 2007-10-25 | 2009-05-21 | Canon U.S. Life Sciences, Inc. | Microchannel surface coating |
| CN101261220B (zh) * | 2008-04-18 | 2010-06-02 | 厦门大学 | 用金纳米粒子检测单链dna碱基突变的方法 |
| TW201043960A (en) * | 2009-06-03 | 2010-12-16 | Univ Nat Chiao Tung | Sensing platform |
| KR101133242B1 (ko) | 2009-11-27 | 2012-04-05 | 국립암센터 | 나노입자의 응집현상을 이용한 유전자 돌연변이 검출법 |
| SG189034A1 (en) * | 2010-09-24 | 2013-05-31 | Agency Science Tech & Res | A nanoprobe comprising gold colloid nanoparticles for multimodality optical imaging of cancer and targeted drug delivery for cancer |
| KR101185703B1 (ko) | 2011-06-24 | 2012-09-24 | 이화여자대학교 산학협력단 | 구아닌을 포함하는 올리고뉴클레오티드를 이용한 금 나노입자의 분석방법 |
| KR101380900B1 (ko) * | 2012-05-08 | 2014-04-10 | 포항공과대학교 산학협력단 | 나이트로 방향족 폭발물의 안정적인 검출을 위한 나노입자 표면 분자체의 합성과 이를 이용한 폭발물 검출 센서 |
| US20140134609A1 (en) * | 2012-08-17 | 2014-05-15 | Agency For Science, Technology And Research | Enzymatic metal nanoparticle sensor for detecting dna binders |
| CN103163095A (zh) * | 2013-03-25 | 2013-06-19 | 江南大学 | 基于纳米银的可视化多功能检测方法 |
| WO2014186901A1 (en) | 2013-05-24 | 2014-11-27 | Gu Frank X | Detection of pathogens using unmodified metal nanoparticles |
| US10465236B2 (en) | 2013-12-23 | 2019-11-05 | University Of Queensland | Nucleic acid detection method and kit |
| CN105219849B (zh) * | 2015-09-16 | 2018-08-21 | 南方医科大学 | 基于未修饰纳米金与双链dna相互作用的比色法检测dna |
| CN105259314B (zh) * | 2015-10-26 | 2017-03-22 | 广东省生态环境与土壤研究所 | 一种铅离子可视化检测方法及检测试剂盒 |
| CN105548086A (zh) * | 2015-12-09 | 2016-05-04 | 上海大学 | 微藻蛋白质的纳米金测试方法 |
| US10400268B2 (en) | 2016-11-02 | 2019-09-03 | The Queen's University Of Belfast | Methods and kits for the detection of DNA |
| KR102256570B1 (ko) * | 2017-01-31 | 2021-05-27 | 한양대학교 산학협력단 | 비색-형광 혼합 모드를 이용한 환경호르몬 검출 방법 |
| US11753681B2 (en) | 2017-11-03 | 2023-09-12 | University Of Washington | Digital nucleic acid amplification using encoded particles |
| CN109187961A (zh) * | 2018-09-19 | 2019-01-11 | 无限极(中国)有限公司 | 一种用于检测黄曲霉毒素b1的定性定量免疫层析试纸条及其制备方法和应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4824776A (en) * | 1985-07-25 | 1989-04-25 | Molecular Biosystems, Inc. | Method for increasing the sensitivity of nucleic acid hybridization assays |
| US5591578A (en) * | 1993-12-10 | 1997-01-07 | California Institute Of Technology | Nucleic acid mediated electron transfer |
| JPH07227299A (ja) * | 1994-02-14 | 1995-08-29 | Kyoto Daiichi Kagaku:Kk | Dnaの特定塩基配列の検出方法及びその装置 |
| US5486962A (en) * | 1994-10-12 | 1996-01-23 | International Business Machines Corporation | Integral hub and disk clamp for a disk drive storage device |
| US5846909A (en) * | 1995-05-22 | 1998-12-08 | University Of Texas System | Molecular level, precision control over the interfacial properties of high-TC superconductor structures and devices |
| US6361944B1 (en) * | 1996-07-29 | 2002-03-26 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| DE69737598T2 (de) * | 1996-07-29 | 2007-12-27 | Nanosphere Inc., Skokie | Nanopartikel mit daran angehefteten oligonukleotiden sowie deren verwendungen |
| US6984491B2 (en) * | 1996-07-29 | 2006-01-10 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| US20030077625A1 (en) * | 1997-05-27 | 2003-04-24 | Hutchison James E. | Particles by facile ligand exchange reactions |
| US6258264B1 (en) * | 1998-04-10 | 2001-07-10 | Transgenomic, Inc. | Non-polar media for polynucleotide separations |
| EP1135682B1 (en) * | 1998-11-30 | 2007-07-11 | Nanosphere, Inc. | Nanoparticles with polymer shells |
| CA2270106C (en) * | 1999-04-23 | 2006-03-14 | Yousef Haj-Ahmad | Nucleic acid purification and process |
| AU2001249459A1 (en) * | 2000-03-24 | 2001-10-08 | The State Of Oregon, Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon | Scaffold-organized clusters and electronic devices made using such clusters |
| US6548264B1 (en) * | 2000-05-17 | 2003-04-15 | University Of Florida | Coated nanoparticles |
| JP3942146B2 (ja) * | 2000-05-30 | 2007-07-11 | 独立行政法人理化学研究所 | 塩基配列検出用基板の製造方法および塩基配列検出方法 |
| CA2383939C (en) * | 2000-06-27 | 2009-12-01 | National Institute Of Advanced Industrial Science And Technology | Novel nucleic acid probes, method for determining nucleic acids by using the probes, and method for analyzing data obtained by the method |
| US6504021B2 (en) * | 2000-07-05 | 2003-01-07 | Edge Biosystems, Inc. | Ion exchange method for DNA purification |
| DE60119170T2 (de) * | 2000-07-11 | 2007-05-24 | Northwestern University, Evanston | Nachweismethode mittels verstärkter silberfärbung |
| US20030018179A1 (en) * | 2001-06-22 | 2003-01-23 | Technische Universitat Dresden | Method for generating nucleation centers for selective heterogeneous growth of metal clusters on DNA molecules |
| WO2003027678A1 (en) * | 2001-09-26 | 2003-04-03 | Psychiatric Genomics, Inc. | Fluorescence proximity assay |
| JP3955225B2 (ja) * | 2002-03-27 | 2007-08-08 | 日立ソフトウエアエンジニアリング株式会社 | 半導体ナノ粒子を用いる反応の反応測定方法及び該測定方法を用いる半導体ナノ粒子の品質評価方法 |
| US20040038264A1 (en) * | 2002-05-14 | 2004-02-26 | Souza Glauco R. | Fractal dimension analysis of nanoparticle aggregates using angle dependent light scattering for the detection and characterization of nucleic acids and proteins |
| US20060166249A1 (en) * | 2003-05-16 | 2006-07-27 | University Of Rochester | Methods for separating short single-stranded nucleic acid from long single-and double-stranded nucleic acid, and associated biomolecular assays |
-
2004
- 2004-05-17 JP JP2006533143A patent/JP2007516426A/ja active Pending
- 2004-05-17 US US10/847,233 patent/US20050059042A1/en not_active Abandoned
- 2004-05-17 WO PCT/US2004/015413 patent/WO2004111602A2/en not_active Ceased
- 2004-05-17 EP EP04752428A patent/EP1634050A4/en not_active Withdrawn
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