JP2007516426A - オリゴヌクレオチドの検出のための比色法および蛍光法 - Google Patents

オリゴヌクレオチドの検出のための比色法および蛍光法 Download PDF

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JP2007516426A
JP2007516426A JP2006533143A JP2006533143A JP2007516426A JP 2007516426 A JP2007516426 A JP 2007516426A JP 2006533143 A JP2006533143 A JP 2006533143A JP 2006533143 A JP2006533143 A JP 2006533143A JP 2007516426 A JP2007516426 A JP 2007516426A
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nucleic acid
target nucleic
solution
hybridization
metal nanoparticles
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JP2007516426A5 (https=
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ルイス ジェイ． ロスバーグ
リ フイシャン
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University of Rochester
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University of Rochester
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6832—Enhancement of hybridisation reaction

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Nanotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
JP2006533143A 2003-05-16 2004-05-17 オリゴヌクレオチドの検出のための比色法および蛍光法 Pending JP2007516426A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47125703P 2003-05-16 2003-05-16
US55279304P 2004-03-12 2004-03-12
PCT/US2004/015413 WO2004111602A2 (en) 2003-05-16 2004-05-17 Colorimetric and fluorescent methods for sensing of oligonucleotides

Publications (2)

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JP2007516426A true JP2007516426A (ja) 2007-06-21
JP2007516426A5 JP2007516426A5 (https=) 2007-08-02

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JP2006533143A Pending JP2007516426A (ja) 2003-05-16 2004-05-17 オリゴヌクレオチドの検出のための比色法および蛍光法

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US (1) US20050059042A1 (https=)
EP (1) EP1634050A4 (https=)
JP (1) JP2007516426A (https=)
WO (1) WO2004111602A2 (https=)

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KR101185703B1 (ko) 2011-06-24 2012-09-24 이화여자대학교 산학협력단 구아닌을 포함하는 올리고뉴클레오티드를 이용한 금 나노입자의 분석방법

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US20080286880A1 (en) * 2004-07-07 2008-11-20 The Penn State Research Foundation Methods and Systems for Nanoparticle Enhancement of Signals
EP1848823A4 (en) * 2005-01-21 2008-06-25 Univ Rochester METHOD FOR SEPARATING SHORT INDIVIDUAL STRUCTURAL NUCLEIC ACID OF LONG SINGLE AND DOUBLE STRANDUCLEIC ACID AND ASSOCIATED BIOMOLECULAR TESTS
US20090221095A1 (en) * 2005-10-13 2009-09-03 Northwestern University Colorimetric Screening of DNA Binding/Intercalating Agents with Gold Nanoparticle Probes
US8057989B2 (en) * 2006-02-10 2011-11-15 The University Of Hong Kong Label-free optical sensing and characterization of biomolecules by d8 or d10 metal complexes
US8309304B2 (en) 2006-02-10 2012-11-13 The University Of Hong Kong Label-free optical sensing and characterization of biomolecules by d8 or d10 metal complexes
KR100828936B1 (ko) * 2006-08-01 2008-05-20 김성천 단일가닥핵산 압타머와 금-나노입자를 이용한 생체분자분석방법
US20090130746A1 (en) * 2007-10-25 2009-05-21 Canon U.S. Life Sciences, Inc. Microchannel surface coating
CN101261220B (zh) * 2008-04-18 2010-06-02 厦门大学 用金纳米粒子检测单链dna碱基突变的方法
TW201043960A (en) * 2009-06-03 2010-12-16 Univ Nat Chiao Tung Sensing platform
KR101133242B1 (ko) 2009-11-27 2012-04-05 국립암센터 나노입자의 응집현상을 이용한 유전자 돌연변이 검출법
SG189034A1 (en) * 2010-09-24 2013-05-31 Agency Science Tech & Res A nanoprobe comprising gold colloid nanoparticles for multimodality optical imaging of cancer and targeted drug delivery for cancer
KR101380900B1 (ko) * 2012-05-08 2014-04-10 포항공과대학교 산학협력단 나이트로 방향족 폭발물의 안정적인 검출을 위한 나노입자 표면 분자체의 합성과 이를 이용한 폭발물 검출 센서
US20140134609A1 (en) * 2012-08-17 2014-05-15 Agency For Science, Technology And Research Enzymatic metal nanoparticle sensor for detecting dna binders
CN103163095A (zh) * 2013-03-25 2013-06-19 江南大学 基于纳米银的可视化多功能检测方法
WO2014186901A1 (en) 2013-05-24 2014-11-27 Gu Frank X Detection of pathogens using unmodified metal nanoparticles
US10465236B2 (en) 2013-12-23 2019-11-05 University Of Queensland Nucleic acid detection method and kit
CN105219849B (zh) * 2015-09-16 2018-08-21 南方医科大学 基于未修饰纳米金与双链dna相互作用的比色法检测dna
CN105259314B (zh) * 2015-10-26 2017-03-22 广东省生态环境与土壤研究所 一种铅离子可视化检测方法及检测试剂盒
CN105548086A (zh) * 2015-12-09 2016-05-04 上海大学 微藻蛋白质的纳米金测试方法
US10400268B2 (en) 2016-11-02 2019-09-03 The Queen's University Of Belfast Methods and kits for the detection of DNA
KR102256570B1 (ko) * 2017-01-31 2021-05-27 한양대학교 산학협력단 비색-형광 혼합 모드를 이용한 환경호르몬 검출 방법
US11753681B2 (en) 2017-11-03 2023-09-12 University Of Washington Digital nucleic acid amplification using encoded particles
CN109187961A (zh) * 2018-09-19 2019-01-11 无限极（中国）有限公司 一种用于检测黄曲霉毒素b1的定性定量免疫层析试纸条及其制备方法和应用

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JPH07227299A (ja) * 1994-02-14 1995-08-29 Kyoto Daiichi Kagaku:Kk Ｄｎａの特定塩基配列の検出方法及びその装置
WO1998004740A1 (en) * 1996-07-29 1998-02-05 Nanosphere Llc Nanoparticles having oligonucleotides attached thereto and uses therefor

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101185703B1 (ko) 2011-06-24 2012-09-24 이화여자대학교 산학협력단 구아닌을 포함하는 올리고뉴클레오티드를 이용한 금 나노입자의 분석방법

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WO2004111602A3 (en) 2006-09-28
WO2004111602A2 (en) 2004-12-23
EP1634050A2 (en) 2006-03-15
EP1634050A4 (en) 2008-06-18
US20050059042A1 (en) 2005-03-17

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