JP2007513877A5 - - Google Patents
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- Publication number
- JP2007513877A5 JP2007513877A5 JP2006539731A JP2006539731A JP2007513877A5 JP 2007513877 A5 JP2007513877 A5 JP 2007513877A5 JP 2006539731 A JP2006539731 A JP 2006539731A JP 2006539731 A JP2006539731 A JP 2006539731A JP 2007513877 A5 JP2007513877 A5 JP 2007513877A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- sulfinyl
- ethene
- chlorophenyl
- methoxyphenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52052303P | 2003-11-14 | 2003-11-14 | |
| US60/520,523 | 2003-11-14 | ||
| PCT/US2004/037293 WO2005046599A2 (en) | 2003-11-14 | 2004-11-08 | Alpha, beta-unsaturated sulfoxides for treating proliferative disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007513877A JP2007513877A (ja) | 2007-05-31 |
| JP2007513877A5 true JP2007513877A5 (https=) | 2007-12-27 |
| JP5196787B2 JP5196787B2 (ja) | 2013-05-15 |
Family
ID=34590471
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006539731A Expired - Fee Related JP5196787B2 (ja) | 2003-11-14 | 2004-11-08 | 増殖性疾患を治療するためのα，β−不飽和スルホキシド |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7744889B2 (https=) |
| EP (1) | EP1689706B1 (https=) |
| JP (1) | JP5196787B2 (https=) |
| KR (1) | KR20060109871A (https=) |
| AU (1) | AU2004289281C1 (https=) |
| CA (1) | CA2546495C (https=) |
| DK (1) | DK1689706T3 (https=) |
| ES (1) | ES2621802T3 (https=) |
| HU (1) | HUE032523T2 (https=) |
| IL (1) | IL174426A (https=) |
| NZ (1) | NZ545995A (https=) |
| WO (1) | WO2005046599A2 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ549962A (en) * | 2004-03-16 | 2010-04-30 | Univ Temple | Substituted phenoxy-and phenylthio-derivatives for treating proliferative disorders |
| JP5156389B2 (ja) * | 2005-01-05 | 2013-03-06 | テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション | 薬剤耐性増殖性疾患の治療剤 |
| WO2006104668A2 (en) * | 2005-03-11 | 2006-10-05 | Temple University - Of The Commonwealth System Of Higher Education | Composition and methods for the treatment of proliferative diseases |
| WO2007005670A2 (en) * | 2005-06-30 | 2007-01-11 | The Research Foundation Of The State University Of New York | Natural and synthetic sulfoxide, selenone and selenoxide analogs and polymer conjugated forms thereof for the modulation of angiogenesis |
| US20110250184A1 (en) * | 2008-12-16 | 2011-10-13 | Onconova Therapeutics ,Inc. | Methods for determining efficacy of a therapeutic regimen against deleterious effects of cytotoxic agents in human |
| GB201010359D0 (en) | 2010-06-21 | 2010-08-04 | Univ Nottingham | Compounds for treating proliferative disorders |
| EP2486923B1 (en) * | 2011-02-11 | 2015-09-09 | Dr. Felix Jäger und Dr. Stefan Drinkuth Laborgemeinschaft OHG | Histone deacetylase (HDAC) inhibiting compounds and method of making same |
| AU2013318206B2 (en) | 2012-09-20 | 2018-07-26 | Temple University - Of The Commonwealth System Of Higher Education | Substituted alkyl diaryl derivatives, methods of preparation and uses |
| AU2014262764B2 (en) * | 2013-05-07 | 2018-11-15 | The Regents Of The University Of California | Radiomitigating pharmaceutical formulations |
| CN104892471B (zh) * | 2015-05-15 | 2020-03-27 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 具有蛋白酪氨酸激酶抑制活性的物质、其制备方法及用途 |
| US10383831B2 (en) * | 2015-08-03 | 2019-08-20 | Temple University—Of the Commonwealth System of Higher Education | 2,4,6-trialkoxystryl aryl sulfones, sulfonamides and carboxamides, and methods of preparation and use |
| CN106432011B (zh) * | 2016-09-18 | 2018-11-02 | 中国医学科学院放射医学研究所 | 一类具有辐射防护作用的新化合物、其制备方法及其药物应用 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3865867A (en) | 1967-06-19 | 1975-02-11 | Monsanto Co | Meta-bifunctional benzenes |
| US3975435A (en) | 1974-03-06 | 1976-08-17 | Givaudan Corporation | Substituted cinnamanilides |
| DK586175A (da) * | 1974-12-28 | 1976-06-29 | Asahi Chemical Ind | Cephalosporin-forbindelser |
| JPH05262733A (ja) * | 1992-03-23 | 1993-10-12 | Sapporo Breweries Ltd | 含硫黄化合物，その製造法及びそれを有効成分とする抗潰瘍剤 |
| US5523302A (en) * | 1993-11-24 | 1996-06-04 | The Du Pont Merck Pharmaceutical Company | Aromatic compounds containing basic and acidic termini useful as fibrinogen receptor antagonists |
| IL164568A0 (en) | 1997-05-14 | 2005-12-18 | Atherogenics Inc | Compounds and methods for the inhibition of the expression of vcam-1 |
| CN1163480C (zh) * | 1997-10-03 | 2004-08-25 | 坦普尔大学 | 苯乙烯砜抗癌剂 |
| US6548553B2 (en) * | 1997-10-03 | 2003-04-15 | Temple University-Of The Commonwealth System Of Higher Education | Styryl sulfone anticancer agents |
| US6201154B1 (en) * | 1999-03-31 | 2001-03-13 | Temple University-Of The Commonwealth Of Higher Education | Z-styryl sulfone anticancer agents |
| JP4596651B2 (ja) * | 1999-04-02 | 2010-12-08 | テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション | （ｅ）−スチリルスルホン抗癌剤 |
| US6762207B1 (en) | 1999-04-02 | 2004-07-13 | Temple University - Of The Commonwealth System Of Higher Education | (E)-styryl sulfone anticancer agents |
| JP2002541101A (ja) * | 1999-04-02 | 2002-12-03 | テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション | スチリルスルホン抗癌剤 |
| US6117364A (en) | 1999-05-27 | 2000-09-12 | Nalco/Exxon Energy Chemicals, L.P. | Acid corrosion inhibitor |
| EP1191929A4 (en) | 1999-06-16 | 2005-02-16 | Univ Temple | (Z) -STYRYL ACETOXYPHENYL SULFIDES AS INHIBITORS OF CYCLO-OXYGENASE |
| WO2001026645A1 (en) * | 1999-10-12 | 2001-04-19 | Temple University-Of The Commonwealth System Of Higher Education | Method for protecting normal cells from cytotoxicity of chemotherapeutic agents |
| US6767926B1 (en) * | 1999-10-12 | 2004-07-27 | Temple University - Of The Commonwealth System Of Higher Education | Method for protecting normal cells from cytotoxicity of chemotherapeutic agents |
| US6541475B2 (en) | 2000-04-14 | 2003-04-01 | Temple University - Of The Commonwealth System Of Higher Education | α, β-unsaturated sulfones for treating proliferative disorders |
| US6486210B2 (en) * | 2000-04-14 | 2002-11-26 | Temple University—Of the Commonwealth System of Higher Education | Substituted styryl benzylsulfones for treating proliferative disorders |
| AU2001296677A1 (en) | 2000-10-05 | 2002-04-15 | Temple University - Of The Commonwealth System Of Higher Education | Substituted (e)-styryl benzylsulfones for treating proliferative disorders |
| DE60112466D1 (de) * | 2000-10-12 | 2005-09-08 | Yamaha Motor Co Ltd | Mischer für gasförmige brennstoffe |
| JP2004521126A (ja) * | 2001-02-27 | 2004-07-15 | テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション | （ｚ）−スチリルベンジルスルホン及びそれらの医薬としての使用 |
| AU2002306604B2 (en) | 2001-02-28 | 2007-09-13 | Onconova Therapeutics, Inc. | N-(Aryl)-2-arylethenesulfonamides and therapeutic uses thereof |
| WO2002069892A2 (en) * | 2001-02-28 | 2002-09-12 | Temple University Of The Commonwealth System Of Higher Education | METHOD FOR PROTECTING CELLS AND TISSUES FROM IONIZING RADIATION TOXICITY WITH α, β UNSATURATED ARYL SULFONES |
| NZ535232A (en) * | 2002-02-28 | 2007-05-31 | Univ Temple | Amino-substituted (E)-2,6-dialkoxystyryl 4-substituted benzylsulfones for treating proliferative disorders |
| NZ549962A (en) * | 2004-03-16 | 2010-04-30 | Univ Temple | Substituted phenoxy-and phenylthio-derivatives for treating proliferative disorders |
| WO2006104668A2 (en) | 2005-03-11 | 2006-10-05 | Temple University - Of The Commonwealth System Of Higher Education | Composition and methods for the treatment of proliferative diseases |
-
2004
- 2004-11-08 WO PCT/US2004/037293 patent/WO2005046599A2/en not_active Ceased
- 2004-11-08 US US10/574,993 patent/US7744889B2/en not_active Expired - Lifetime
- 2004-11-08 NZ NZ545995A patent/NZ545995A/en not_active IP Right Cessation
- 2004-11-08 ES ES04816944.5T patent/ES2621802T3/es not_active Expired - Lifetime
- 2004-11-08 JP JP2006539731A patent/JP5196787B2/ja not_active Expired - Fee Related
- 2004-11-08 KR KR1020067007327A patent/KR20060109871A/ko not_active Ceased
- 2004-11-08 HU HUE04816944A patent/HUE032523T2/en unknown
- 2004-11-08 DK DK04816944.5T patent/DK1689706T3/da active
- 2004-11-08 AU AU2004289281A patent/AU2004289281C1/en not_active Expired
- 2004-11-08 EP EP04816944.5A patent/EP1689706B1/en not_active Expired - Lifetime
- 2004-11-08 CA CA2546495A patent/CA2546495C/en not_active Expired - Lifetime
-
2006
- 2006-03-20 IL IL174426A patent/IL174426A/en active IP Right Grant
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