JP2007513326A5 - - Google Patents
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- Publication number
- JP2007513326A5 JP2007513326A5 JP2006539829A JP2006539829A JP2007513326A5 JP 2007513326 A5 JP2007513326 A5 JP 2007513326A5 JP 2006539829 A JP2006539829 A JP 2006539829A JP 2006539829 A JP2006539829 A JP 2006539829A JP 2007513326 A5 JP2007513326 A5 JP 2007513326A5
- Authority
- JP
- Japan
- Prior art keywords
- fragment
- cell
- tissue
- molecule
- peptide antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51879003P | 2003-11-10 | 2003-11-10 | |
| US60/518,790 | 2003-11-10 | ||
| PCT/US2004/037569 WO2005046449A2 (en) | 2003-11-10 | 2004-11-10 | Soluble tcr molecules and methods of use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007513326A JP2007513326A (ja) | 2007-05-24 |
| JP2007513326A5 true JP2007513326A5 (https=) | 2007-12-27 |
| JP4773361B2 JP4773361B2 (ja) | 2011-09-14 |
Family
ID=34590303
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006539829A Expired - Lifetime JP4773361B2 (ja) | 2003-11-10 | 2004-11-10 | 可溶性tcr分子とその使用方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US8772451B2 (https=) |
| EP (1) | EP1691661B1 (https=) |
| JP (1) | JP4773361B2 (https=) |
| KR (1) | KR101131297B1 (https=) |
| CN (2) | CN1901839A (https=) |
| AU (1) | AU2004289316B2 (https=) |
| CA (1) | CA2544483C (https=) |
| WO (1) | WO2005046449A2 (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1982176A1 (en) * | 2006-01-30 | 2008-10-22 | Dako Denmark A/S | High-speed quantification of antigen specific t-cells in whole blood by flow cytometry |
| JP4748542B2 (ja) * | 2006-02-24 | 2011-08-17 | 古河電気工業株式会社 | フローサイトメトリーによる生体分子の定量システム、及び定量方法 |
| EP2361930A3 (en) | 2007-03-26 | 2011-10-26 | Dako Denmark A/S | Multimers of MHC-peptide complexes and uses thereof in Borrelia infectious diseases |
| DK2160401T3 (da) | 2007-05-11 | 2014-10-20 | Altor Bioscience Corp | Fusionsmolekyler og il-15-varianter |
| EP3620465B1 (en) * | 2007-07-03 | 2025-02-19 | Dako Denmark A/S | Improved methods for generation, labeling and use of mhc multimers |
| US10611818B2 (en) | 2007-09-27 | 2020-04-07 | Agilent Technologies, Inc. | MHC multimers in tuberculosis diagnostics, vaccine and therapeutics |
| DK2254592T3 (da) | 2008-02-28 | 2019-09-09 | Dako Denmark As | MHC-multimerer til Borrelia-diagnostik og sygdom |
| WO2009117117A1 (en) * | 2008-03-19 | 2009-09-24 | Altor Bioscience Corporation | T cell receptor fusions and conjugates and methods of use there of |
| US10722562B2 (en) * | 2008-07-23 | 2020-07-28 | Immudex Aps | Combinatorial analysis and repair |
| GB0817244D0 (en) * | 2008-09-20 | 2008-10-29 | Univ Cardiff | Use of a protein kinase inhibitor to detect immune cells, such as T cells |
| US11992518B2 (en) | 2008-10-02 | 2024-05-28 | Agilent Technologies, Inc. | Molecular vaccines for infectious disease |
| WO2010037402A1 (en) | 2008-10-02 | 2010-04-08 | Dako Denmark A/S | Molecular vaccines for infectious disease |
| EP2258719A1 (en) * | 2009-05-19 | 2010-12-08 | Max-Delbrück-Centrum für Molekulare Medizin (MDC) | Multiple target T cell receptor |
| US11053299B2 (en) | 2010-09-21 | 2021-07-06 | Immunity Bio, Inc. | Superkine |
| CN107880136B (zh) | 2010-09-21 | 2021-11-12 | 阿尔托生物科学有限公司 | 多聚体il-15可溶性融合分子与其制造与使用方法 |
| WO2012058627A2 (en) * | 2010-10-29 | 2012-05-03 | Miqin Zhang | Pre-targeted nanoparticle system and method for labeling biological particles |
| CA2945816A1 (en) | 2014-04-15 | 2015-10-22 | University Of Virginia Patent Foundation | Isolated t cell receptors and methods of use therefor |
| CA3151221C (en) | 2014-06-30 | 2026-01-13 | Altor Bioscience Corporation | Il-15-based molecules and methods of use thereof |
| AU2017271593B2 (en) | 2016-05-27 | 2021-04-22 | Altor Bioscience Corporation | Construction and characterization of multimeric IL-15-based molecules with CD3 binding domains |
| WO2018026018A1 (ja) * | 2016-08-05 | 2018-02-08 | 国立大学法人東北大学 | T細胞受容体の認識機構を用いたがん又は感染症の治療及び診断 |
| CN118562016A (zh) | 2016-10-21 | 2024-08-30 | 艾尔特生物科技公司 | 基于多聚体il-15的分子 |
| CN117986384A (zh) | 2017-03-06 | 2024-05-07 | 艾尔特生物科技公司 | 与il-12和il-18的基于il-15的融合物 |
| EP3592776A4 (en) * | 2017-03-08 | 2021-01-06 | Agency for Science, Technology and Research | T-CELL RECEPTOR LIKE ANTIBODIES THAT BIND TO THE P53 MHC CLASS I COMPLEX |
| US20190048055A1 (en) | 2017-03-31 | 2019-02-14 | Altor Bioscience Corporation | Alt-803 in combination with anti-cd38 antibody for cancer therapies |
| EP3676289B1 (en) | 2017-08-28 | 2026-03-04 | Altor BioScience, LLC | Il-15-based fusions to il-7 and il-21 |
| AU2018345400B2 (en) * | 2017-10-05 | 2024-06-20 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods for selectively expanding cells expressing a TCR with a murine constant region |
| TW202003011A (zh) | 2018-03-26 | 2020-01-16 | 美商艾爾特生物科技責任有限公司 | 抗PDL1、IL-15及TGF-β受體組合分子 |
| US20220275043A1 (en) | 2018-07-17 | 2022-09-01 | Massachusetts Institute Of Technology | Soluble multimeric immunoglobulin-scaffold based fusion proteins and uses thereof |
| US12258373B2 (en) | 2018-12-17 | 2025-03-25 | Immudex Aps | Panel comprising Borrelia MHC multimers |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US82719A (en) * | 1868-10-06 | Improved mode of preserving fruits, meats, vegetables | ||
| US171552A (en) * | 1875-12-28 | Improvement in wash-boards | ||
| US253632A (en) * | 1882-02-14 | Heney j | ||
| US34513A (en) * | 1862-02-25 | Improvement in machines for stacking hay | ||
| US198144A (en) * | 1877-12-11 | Improvement in devices for decorating vases | ||
| US91079A (en) * | 1869-06-08 | Improvement in device for operating throttle-valves | ||
| US144474A (en) * | 1873-11-11 | Improvement in the means for propelling vessels | ||
| US4384193A (en) | 1981-06-09 | 1983-05-17 | Immulok, Inc. | Incubating device for specimen mounted on glass slides in immunoassays |
| ATE243754T1 (de) * | 1987-05-21 | 2003-07-15 | Micromet Ag | Multifunktionelle proteine mit vorbestimmter zielsetzung |
| FR2698880B1 (fr) * | 1992-11-25 | 1995-02-24 | Inst Nat Sante Rech Med | Procédé de production de récepteurs T solubles, produits ainsi obtenus et leur utilisation dans des compositions diagnostiques ou thérapeutiques. |
| US7074904B2 (en) | 1994-07-29 | 2006-07-11 | Altor Bioscience Corporation | MHC complexes and uses thereof |
| WO1996018105A1 (en) | 1994-12-06 | 1996-06-13 | The President And Fellows Of Harvard College | Single chain t-cell receptor |
| US5869270A (en) | 1996-01-31 | 1999-02-09 | Sunol Molecular Corporation | Single chain MHC complexes and uses thereof |
| DE19616997A1 (de) | 1996-04-27 | 1997-10-30 | Boehringer Mannheim Gmbh | Verfahren zur automatisierten mikroskopunterstützten Untersuchung von Gewebeproben oder Körperflüssigkeitsproben |
| WO1999018129A1 (en) * | 1997-10-02 | 1999-04-15 | Sunol Molecular Corporation | Soluble single-chain t-cell receptor proteins |
| US6232445B1 (en) | 1997-10-29 | 2001-05-15 | Sunol Molecular Corporation | Soluble MHC complexes and methods of use thereof |
| WO1999060120A2 (en) * | 1998-05-19 | 1999-11-25 | Avidex Limited | Soluble t cell receptor |
| ES2293748T3 (es) | 1998-10-21 | 2008-03-16 | Altor Bioscience Corporation | Moleculas de fijacion poliespecificas y usos de las mismas. |
| JP2002543854A (ja) | 1999-05-14 | 2002-12-24 | カイロン コーポレイション | 癌におけるetsドメインタンパク質の発現 |
| JP4972264B2 (ja) | 1999-12-06 | 2012-07-11 | ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ イリノイ | 高親和性tcrタンパク質および方法 |
| US6406840B1 (en) | 1999-12-17 | 2002-06-18 | Biomosaic Systems, Inc. | Cell arrays and the uses thereof |
| EP1118661A1 (en) | 2000-01-13 | 2001-07-25 | Het Nederlands Kanker Instituut | T cell receptor libraries |
| KR20020097181A (ko) | 2000-02-22 | 2002-12-31 | 제노스펙트라 인코포레이티드 | 마이크로어레이 제작 기술 및 장치 |
| US20020058235A1 (en) * | 2000-02-29 | 2002-05-16 | Dinnerstein Mitchell Elliot | Jack switch talking block |
| CA2410642A1 (en) * | 2000-05-25 | 2001-11-29 | Sunol Molecular Corporation | Modulation of t-cell receptor interactions |
| EP2322228B1 (en) * | 2000-06-05 | 2018-01-10 | Altor BioScience Corporation | T cell receptor fusion proteins and conjugates and methods of use thereof |
| US6466690C1 (en) | 2000-12-19 | 2008-11-18 | Bacus Res Lab Inc | Method and apparatus for processing an image of a tissue sample microarray |
| AU2002316190B8 (en) * | 2001-06-05 | 2009-01-29 | Altor Bioscience Corporation | p53 binding T cell receptor molecules and uses thereof |
| US6642661B2 (en) | 2001-08-28 | 2003-11-04 | Tokyo Electron Limited | Method to affect spatial distribution of harmonic generation in a capacitive discharge reactor |
| JP2006523437A (ja) * | 2002-12-03 | 2006-10-19 | アヴィデックス リミテッド | レセプター複合体 |
| DK1796237T3 (da) * | 2005-12-13 | 2007-10-29 | Nexans Sa | Elektrisk gennemföring til forbindelse af en supraledende anordning med en anordning ved rumtemperatur |
| WO2009117117A1 (en) * | 2008-03-19 | 2009-09-24 | Altor Bioscience Corporation | T cell receptor fusions and conjugates and methods of use there of |
| TWM523243U (zh) | 2015-04-01 | 2016-06-01 | 嚴介宏 | 手機轉接裝置及系統 |
-
2004
- 2004-11-10 US US10/985,271 patent/US8772451B2/en not_active Expired - Lifetime
- 2004-11-10 EP EP04818691.0A patent/EP1691661B1/en not_active Expired - Lifetime
- 2004-11-10 CN CNA2004800401834A patent/CN1901839A/zh active Pending
- 2004-11-10 AU AU2004289316A patent/AU2004289316B2/en not_active Expired
- 2004-11-10 WO PCT/US2004/037569 patent/WO2005046449A2/en not_active Ceased
- 2004-11-10 JP JP2006539829A patent/JP4773361B2/ja not_active Expired - Lifetime
- 2004-11-10 CN CN201510413443.8A patent/CN105021814B/zh not_active Expired - Lifetime
- 2004-11-10 KR KR1020067011529A patent/KR101131297B1/ko not_active Expired - Lifetime
- 2004-11-10 CA CA2544483A patent/CA2544483C/en not_active Expired - Lifetime
-
2014
- 2014-02-18 US US14/182,888 patent/US9290560B2/en not_active Expired - Lifetime
-
2016
- 2016-02-10 US US15/040,724 patent/US20160199523A1/en not_active Abandoned
-
2019
- 2019-04-29 US US16/398,226 patent/US20190269807A1/en not_active Abandoned
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