JP2007513326A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2007513326A5 JP2007513326A5 JP2006539829A JP2006539829A JP2007513326A5 JP 2007513326 A5 JP2007513326 A5 JP 2007513326A5 JP 2006539829 A JP2006539829 A JP 2006539829A JP 2006539829 A JP2006539829 A JP 2006539829A JP 2007513326 A5 JP2007513326 A5 JP 2007513326A5
- Authority
- JP
- Japan
- Prior art keywords
- fragment
- cell
- tissue
- molecule
- peptide antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51879003P | 2003-11-10 | 2003-11-10 | |
| US60/518,790 | 2003-11-10 | ||
| PCT/US2004/037569 WO2005046449A2 (en) | 2003-11-10 | 2004-11-10 | Soluble tcr molecules and methods of use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007513326A JP2007513326A (ja) | 2007-05-24 |
| JP2007513326A5 true JP2007513326A5 (https=) | 2007-12-27 |
| JP4773361B2 JP4773361B2 (ja) | 2011-09-14 |
Family
ID=34590303
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006539829A Expired - Lifetime JP4773361B2 (ja) | 2003-11-10 | 2004-11-10 | 可溶性tcr分子とその使用方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US8772451B2 (https=) |
| EP (1) | EP1691661B1 (https=) |
| JP (1) | JP4773361B2 (https=) |
| KR (1) | KR101131297B1 (https=) |
| CN (2) | CN105021814B (https=) |
| AU (1) | AU2004289316B2 (https=) |
| CA (1) | CA2544483C (https=) |
| WO (1) | WO2005046449A2 (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090061478A1 (en) * | 2006-01-30 | 2009-03-05 | Lene Have Poulsen | High-Speed Quantification of Antigen Specific T-Cells in Whole Blood by Flow Cytometry |
| WO2007097377A1 (ja) | 2006-02-24 | 2007-08-30 | The Furukawa Electric Co., Ltd. | フローサイトメトリーによる生体分子の定量システム、その定量方法、細胞の検出・分取システム、その検出・分取方法、それらに用いる蛍光シリカ粒子、及び複数個の蛍光シリカ粒子を組み合わせたキット |
| WO2008116468A2 (en) | 2007-03-26 | 2008-10-02 | Dako Denmark A/S | Mhc peptide complexes and uses thereof in infectious diseases |
| CN101743249B (zh) | 2007-05-11 | 2017-08-08 | 阿尔托生物科学有限公司 | 融合分子与il‑15变异体 |
| EP3620465B1 (en) | 2007-07-03 | 2025-02-19 | Dako Denmark A/S | Improved methods for generation, labeling and use of mhc multimers |
| US10611818B2 (en) | 2007-09-27 | 2020-04-07 | Agilent Technologies, Inc. | MHC multimers in tuberculosis diagnostics, vaccine and therapeutics |
| DK2254592T3 (da) | 2008-02-28 | 2019-09-09 | Dako Denmark As | MHC-multimerer til Borrelia-diagnostik og sygdom |
| US20110070191A1 (en) * | 2008-03-19 | 2011-03-24 | Wong Hing C | T cell receptor fusions and conjugates and methods of use there of |
| WO2010009735A2 (en) * | 2008-07-23 | 2010-01-28 | Dako Denmark A/S | Combinatorial analysis and repair |
| GB0817244D0 (en) * | 2008-09-20 | 2008-10-29 | Univ Cardiff | Use of a protein kinase inhibitor to detect immune cells, such as T cells |
| WO2010037402A1 (en) | 2008-10-02 | 2010-04-08 | Dako Denmark A/S | Molecular vaccines for infectious disease |
| US11992518B2 (en) | 2008-10-02 | 2024-05-28 | Agilent Technologies, Inc. | Molecular vaccines for infectious disease |
| EP2258719A1 (en) * | 2009-05-19 | 2010-12-08 | Max-Delbrück-Centrum für Molekulare Medizin (MDC) | Multiple target T cell receptor |
| US11053299B2 (en) | 2010-09-21 | 2021-07-06 | Immunity Bio, Inc. | Superkine |
| US8507222B2 (en) | 2010-09-21 | 2013-08-13 | Altor Bioscience Corporation | Multimeric IL-15 soluble fusion molecules and methods of making and using same |
| WO2012058627A2 (en) * | 2010-10-29 | 2012-05-03 | Miqin Zhang | Pre-targeted nanoparticle system and method for labeling biological particles |
| EP3137100B1 (en) | 2014-04-15 | 2023-12-20 | University Of Virginia Patent Foundation | Isolated t cell receptors and methods of use therefor |
| KR102762243B1 (ko) | 2014-06-30 | 2025-02-05 | 알토 바이오사이언스 엘엘씨 | Il-15-베이즈드 분자 및 이의 사용 방법 |
| US10865230B2 (en) | 2016-05-27 | 2020-12-15 | Altor Bioscience, Llc | Construction and characterization of multimeric IL-15-based molecules with CD3 binding domains |
| WO2018026018A1 (ja) * | 2016-08-05 | 2018-02-08 | 国立大学法人東北大学 | T細胞受容体の認識機構を用いたがん又は感染症の治療及び診断 |
| EP4613776A3 (en) | 2016-10-21 | 2025-11-26 | Altor BioScience Corporation | Multimeric il-15-based molecules |
| KR102867975B1 (ko) | 2017-03-06 | 2025-10-14 | 알토 바이오사이언스 엘엘씨 | Il-12 및 il-18로의 il-15-기반 융합 |
| EP3778646A1 (en) * | 2017-03-08 | 2021-02-17 | Agency for Science, Technology and Research | T cell receptor like antibodies that bind to p53-mhc class i complex |
| US20190048055A1 (en) | 2017-03-31 | 2019-02-14 | Altor Bioscience Corporation | Alt-803 in combination with anti-cd38 antibody for cancer therapies |
| JP2020533971A (ja) | 2017-08-28 | 2020-11-26 | アルター・バイオサイエンス・コーポレーション | Il−15をベースとするil−7及びil−21への融合物 |
| AU2018345400B2 (en) * | 2017-10-05 | 2024-06-20 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods for selectively expanding cells expressing a TCR with a murine constant region |
| US11168138B2 (en) | 2018-03-26 | 2021-11-09 | Altor Bioscience, Llc | Anti-PDL1, IL-15 and TGF-beta receptor combination molecules |
| WO2020018715A1 (en) | 2018-07-17 | 2020-01-23 | Massachusetts Institute Of Technology | Soluble multimeric immunoglobulin-scaffold based fusion proteins and uses thereof |
| WO2020127222A2 (en) | 2018-12-17 | 2020-06-25 | Immudex Aps | Panel comprising borrelia mhc multimers |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US91079A (en) * | 1869-06-08 | Improvement in device for operating throttle-valves | ||
| US171552A (en) * | 1875-12-28 | Improvement in wash-boards | ||
| US144474A (en) * | 1873-11-11 | Improvement in the means for propelling vessels | ||
| US82719A (en) * | 1868-10-06 | Improved mode of preserving fruits, meats, vegetables | ||
| US34513A (en) * | 1862-02-25 | Improvement in machines for stacking hay | ||
| US198144A (en) * | 1877-12-11 | Improvement in devices for decorating vases | ||
| US253632A (en) * | 1882-02-14 | Heney j | ||
| US4384193A (en) | 1981-06-09 | 1983-05-17 | Immulok, Inc. | Incubating device for specimen mounted on glass slides in immunoassays |
| ATE243754T1 (de) * | 1987-05-21 | 2003-07-15 | Micromet Ag | Multifunktionelle proteine mit vorbestimmter zielsetzung |
| FR2698880B1 (fr) * | 1992-11-25 | 1995-02-24 | Inst Nat Sante Rech Med | Procédé de production de récepteurs T solubles, produits ainsi obtenus et leur utilisation dans des compositions diagnostiques ou thérapeutiques. |
| US7074904B2 (en) | 1994-07-29 | 2006-07-11 | Altor Bioscience Corporation | MHC complexes and uses thereof |
| WO1996018105A1 (en) | 1994-12-06 | 1996-06-13 | The President And Fellows Of Harvard College | Single chain t-cell receptor |
| US5869270A (en) | 1996-01-31 | 1999-02-09 | Sunol Molecular Corporation | Single chain MHC complexes and uses thereof |
| DE19616997A1 (de) | 1996-04-27 | 1997-10-30 | Boehringer Mannheim Gmbh | Verfahren zur automatisierten mikroskopunterstützten Untersuchung von Gewebeproben oder Körperflüssigkeitsproben |
| ATE533784T1 (de) * | 1997-10-02 | 2011-12-15 | Altor Bioscience Corp | Lösliche, einzelkettige proteine des t- zellrezeptors |
| US6232445B1 (en) | 1997-10-29 | 2001-05-15 | Sunol Molecular Corporation | Soluble MHC complexes and methods of use thereof |
| WO1999060120A2 (en) * | 1998-05-19 | 1999-11-25 | Avidex Limited | Soluble t cell receptor |
| DE69936927T2 (de) * | 1998-10-21 | 2008-05-15 | Altor Bioscience Corp., Miramar | Polyspezifische bindemoleküle und deren verwendung |
| WO2000070092A1 (en) | 1999-05-14 | 2000-11-23 | Chiron Corporation | Expression of ets-domain proteins in cancer |
| MXPA02005559A (es) | 1999-12-06 | 2004-09-10 | Univ Illinois | Proteinas de tcr de alta afinidad y metodos. |
| US6406840B1 (en) | 1999-12-17 | 2002-06-18 | Biomosaic Systems, Inc. | Cell arrays and the uses thereof |
| EP1118661A1 (en) | 2000-01-13 | 2001-07-25 | Het Nederlands Kanker Instituut | T cell receptor libraries |
| CN1404415A (zh) | 2000-02-22 | 2003-03-19 | 基因谱公司 | 微阵列制造技术及设备 |
| US20020058235A1 (en) * | 2000-02-29 | 2002-05-16 | Dinnerstein Mitchell Elliot | Jack switch talking block |
| EP1287363A2 (en) | 2000-05-25 | 2003-03-05 | Sunol Molecular Corporation | Modulation of t-cell receptor interactions |
| AU7524601A (en) * | 2000-06-05 | 2001-12-17 | Sunol Molecular Corp | T cell receptor fusions and conjugates and methods of use thereof |
| US6466690C1 (en) | 2000-12-19 | 2008-11-18 | Bacus Res Lab Inc | Method and apparatus for processing an image of a tissue sample microarray |
| CA2487779C (en) * | 2001-06-05 | 2012-10-02 | Altor Bioscience Corporation | P53 binding t cell receptor molecules and uses thereof |
| US6642661B2 (en) | 2001-08-28 | 2003-11-04 | Tokyo Electron Limited | Method to affect spatial distribution of harmonic generation in a capacitive discharge reactor |
| EP1567553A2 (en) * | 2002-12-03 | 2005-08-31 | Avidex Ltd. | Complexes of receptors |
| DE502005001151D1 (de) * | 2005-12-13 | 2007-09-13 | Nexans S A | Elektrische Durchführung zur Verbindung einer supraleitenden Einrichtung mit einer bei Raumtemperatur befindlichen Einrichtung |
| US20110070191A1 (en) * | 2008-03-19 | 2011-03-24 | Wong Hing C | T cell receptor fusions and conjugates and methods of use there of |
| TWM523243U (zh) | 2015-04-01 | 2016-06-01 | 嚴介宏 | 手機轉接裝置及系統 |
-
2004
- 2004-11-10 KR KR1020067011529A patent/KR101131297B1/ko not_active Expired - Lifetime
- 2004-11-10 US US10/985,271 patent/US8772451B2/en not_active Expired - Lifetime
- 2004-11-10 EP EP04818691.0A patent/EP1691661B1/en not_active Expired - Lifetime
- 2004-11-10 CN CN201510413443.8A patent/CN105021814B/zh not_active Expired - Lifetime
- 2004-11-10 JP JP2006539829A patent/JP4773361B2/ja not_active Expired - Lifetime
- 2004-11-10 CA CA2544483A patent/CA2544483C/en not_active Expired - Lifetime
- 2004-11-10 WO PCT/US2004/037569 patent/WO2005046449A2/en not_active Ceased
- 2004-11-10 CN CNA2004800401834A patent/CN1901839A/zh active Pending
- 2004-11-10 AU AU2004289316A patent/AU2004289316B2/en not_active Expired
-
2014
- 2014-02-18 US US14/182,888 patent/US9290560B2/en not_active Expired - Lifetime
-
2016
- 2016-02-10 US US15/040,724 patent/US20160199523A1/en not_active Abandoned
-
2019
- 2019-04-29 US US16/398,226 patent/US20190269807A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2007513326A5 (https=) | ||
| ES2424269T3 (es) | Inmuno-PCR sándwich por desplazamiento | |
| US20240003892A1 (en) | Heterogeneous single cell profiling using molecular barcoding | |
| Poetz et al. | Protein microarrays: catching the proteome | |
| Lee et al. | Emerging protein array technologies for proteomics | |
| Templin et al. | Protein microarrays: promising tools for proteomic research | |
| KR102039756B1 (ko) | 뉴클레오솜 부가물의 검출 방법 | |
| CA2659745A1 (en) | Methods and systems for detecting and/or sorting targets | |
| Liang et al. | Colorimetric detection of protein microarrays based on nanogold probe coupled with silver enhancement | |
| EP3365681B1 (en) | Method for detecting nucleosomes containing histone modifications and variants | |
| ES2899191T3 (es) | Péptidos y procedimientos de detección de alergia alimentaria | |
| CN102703453B (zh) | 特异性识别链霉素的dna适配体及其应用 | |
| KR102929834B1 (ko) | 결합에 의한 공국재화 샌드위치 어세이 | |
| US20230417742A1 (en) | Improved assays to detect nucleosome modifications using antibody-targeted enzyme digestion | |
| CN115380218A (zh) | 用于多重化的连接-共定位夹心测定 | |
| CN116917496A (zh) | 循环转录因子分析 | |
| Joos et al. | Protein microarrays: potentials and limitations | |
| Gong et al. | A facile strategy for multiplex protein detection by a fluorescent microsphere-based digital immunoassay | |
| Tyagi et al. | Detection of embryonic stem cell lysate biomarkers by surface plasmon resonance with reduced nonspecific adsorption | |
| US20250164503A1 (en) | Engineered recombinant protein-binding domains as detection reagents | |
| EP1141392A1 (en) | Fluorescent intensity assay for protein or peptide binding to nucleic acids | |
| Taussig et al. | Progress in antibody arrays | |
| JP2009517381A5 (https=) | ||
| JP2022553737A5 (https=) | ||
| JP2006525351A5 (https=) |