JP2007511539A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2007511539A5 JP2007511539A5 JP2006540034A JP2006540034A JP2007511539A5 JP 2007511539 A5 JP2007511539 A5 JP 2007511539A5 JP 2006540034 A JP2006540034 A JP 2006540034A JP 2006540034 A JP2006540034 A JP 2006540034A JP 2007511539 A5 JP2007511539 A5 JP 2007511539A5
- Authority
- JP
- Japan
- Prior art keywords
- aat
- composition
- concentration
- pharmaceutical composition
- antioxidant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52054903P | 2003-11-14 | 2003-11-14 | |
| PCT/US2004/038650 WO2005048985A2 (en) | 2003-11-14 | 2004-11-11 | Alpha 1-antitrypsin compositions and treatment methods using such compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007511539A JP2007511539A (ja) | 2007-05-10 |
| JP2007511539A5 true JP2007511539A5 (https=) | 2007-12-27 |
Family
ID=34619481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006540034A Pending JP2007511539A (ja) | 2003-11-14 | 2004-11-11 | α1−抗トリプシン組成物およびこのような組成物を用いた処置方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20080312136A1 (https=) |
| EP (1) | EP1684719B1 (https=) |
| JP (1) | JP2007511539A (https=) |
| AT (1) | ATE530165T1 (https=) |
| AU (1) | AU2004290587B2 (https=) |
| CA (1) | CA2545855A1 (https=) |
| DK (1) | DK1684719T3 (https=) |
| ES (1) | ES2375706T3 (https=) |
| PL (1) | PL1684719T3 (https=) |
| PT (1) | PT1684719E (https=) |
| SI (1) | SI1684719T1 (https=) |
| WO (1) | WO2005048985A2 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2559062A1 (en) * | 2004-03-09 | 2005-09-22 | Arriva Pharmaceuticals, Inc. | Treatment of chronic obstructive pulmonary disease by low dose inhalation of protease inhibitor |
| ES2399449T3 (es) | 2006-02-09 | 2013-04-01 | Kamada Ltd. | Administración pulmonar de un inhibidor de proteinasa alfa-1 |
| CN102131827A (zh) * | 2007-12-13 | 2011-07-20 | 葛兰素集团有限公司 | 用于肺部传递给药的组合物 |
| TR201809898T4 (tr) | 2009-11-03 | 2018-07-23 | Grifols Therapeutics Llc | Alfa-1 protei̇naz i̇nhi̇bi̇törüne yöneli̇k bi̇leşi̇m, yöntem ve ki̇t. |
| PT2503995T (pt) | 2009-11-24 | 2017-11-23 | Grifols Therapeutics Inc | Métodos de liofilização, composições e kits |
| US20130034573A1 (en) * | 2009-12-22 | 2013-02-07 | Celldex Therapeutics, Inc. | Vaccine compositions |
| CA2844878C (en) * | 2011-12-30 | 2017-11-28 | Grifols, S.A. | Alpha1-proteinase inhibitor for delaying the onset or progression of pulmonary exacerbations |
| ES2799153T3 (es) * | 2013-03-29 | 2020-12-15 | Univ Colorado Regents | Alfa 1 antitripsina para uso en la preparación de un sujeto para trasplante |
| WO2015191892A2 (en) * | 2014-06-11 | 2015-12-17 | Beth Israel Deaconess Medical Center, Inc. | α1-ANTITRYPSIN COMPOSITIONS AND METHODS OF TREATING AUTOIMMUNE DISEASES |
| US20210085764A1 (en) * | 2016-12-22 | 2021-03-25 | Kamada Ltd. | Dry powder formulations of alpha-1 antitrypsin |
| CA3054267A1 (en) * | 2017-02-21 | 2018-08-30 | Kamada Ltd. | Methods and uses of alpha 1-antitrypsin for early intervention in pulmonary diseases |
| WO2018183705A1 (en) | 2017-03-29 | 2018-10-04 | Cornell University | Oxidation-resistant aat gene therapy |
| WO2019087184A1 (en) * | 2017-10-31 | 2019-05-09 | Kamada Ltd | Methods and compositions for reducing lung injury associated with lung transplantation |
| IL267923B2 (en) | 2018-08-02 | 2023-06-01 | Grifols Worldwide Operations Ltd | The composition containing the most concentrated alpha-1 type protein inhibitor and a method for obtaining it |
| CN113365513B (zh) * | 2018-10-23 | 2025-04-25 | G·E·霍格 | 用于治疗肺的组合物和方法 |
| WO2020163703A1 (en) | 2019-02-08 | 2020-08-13 | Krystal Biotech, Inc. | Compositions and methods for delivering cftr polypeptides |
| US20210189427A1 (en) * | 2019-12-20 | 2021-06-24 | Krystal Biotech, Inc. | Compositions and methods for gene delivery to the airways and/or lungs |
| GB202102258D0 (en) * | 2021-02-17 | 2021-03-31 | Arecor Ltd | Novel composition |
Family Cites Families (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4150071A (en) * | 1977-08-26 | 1979-04-17 | Respiratory Care, Inc. | Nebulizer |
| IT1105653B (it) * | 1978-06-20 | 1985-11-04 | Craighero Margherita | Apparecchio aerosolizzatore |
| US4253468A (en) * | 1978-08-14 | 1981-03-03 | Steven Lehmbeck | Nebulizer attachment |
| US4198969A (en) * | 1978-10-06 | 1980-04-22 | Baxter Travenol Laboratories, Inc. | Suction-operated nebulizer |
| US4453542A (en) * | 1980-12-08 | 1984-06-12 | Vortran Corporation | Vortex-generating medical products |
| US4775622A (en) * | 1982-03-08 | 1988-10-04 | Genentech, Inc. | Expression, processing and secretion of heterologous protein by yeast |
| US5218091A (en) * | 1982-08-13 | 1993-06-08 | Zymogenetics, Inc. | Glycolytic promoters for regulated protein expression: protease inhibitor |
| US4599311A (en) | 1982-08-13 | 1986-07-08 | Kawasaki Glenn H | Glycolytic promotersfor regulated protein expression: protease inhibitor |
| US5010003A (en) * | 1983-04-25 | 1991-04-23 | Genentech, Inc. | Use of yeast homologous signals to secrete heterologous proteins |
| WO1985002346A1 (en) * | 1983-11-28 | 1985-06-06 | Vortran Corporation | Gas-powered nebulizer |
| US4711848A (en) * | 1984-03-14 | 1987-12-08 | Zymogenetics, Inc. | Site specific mutagenesis in alpha-1-antitrypsin |
| US4940661A (en) * | 1984-05-17 | 1990-07-10 | Genentech, Inc. | Metallothionein transcription control sequences and use thereof |
| US4931373A (en) * | 1984-05-25 | 1990-06-05 | Zymogenetics, Inc. | Stable DNA constructs for expression of α-1 antitrypsin |
| US4732973A (en) * | 1984-06-14 | 1988-03-22 | Chiron Corporation | Active site modified protease α-1-antitrypsin inhibitors |
| US4752576A (en) * | 1984-06-14 | 1988-06-21 | Chiron Corporation | Expression of α-1 antitrypsin in yeast |
| US4837148A (en) * | 1984-10-30 | 1989-06-06 | Phillips Petroleum Company | Autonomous replication sequences for yeast strains of the genus pichia |
| US5013652A (en) * | 1986-10-14 | 1991-05-07 | Genex Corporation | Composite yeast vectors |
| US5114917A (en) * | 1986-12-24 | 1992-05-19 | John Lezdey | Treatment of inflammation using alpha 1-antichymotrypsin |
| US5166134A (en) * | 1986-12-24 | 1992-11-24 | John Lezdey | Treatment of allergic rhinitis |
| US4839283A (en) * | 1986-12-30 | 1989-06-13 | Zymogenetics, Inc. | Method of expressing alpha-1-antitrypsin in yeast |
| JP2656944B2 (ja) * | 1987-04-30 | 1997-09-24 | クーパー ラボラトリーズ | タンパク質性治療剤のエアロゾール化 |
| US4929555A (en) * | 1987-10-19 | 1990-05-29 | Phillips Petroleum Company | Pichia transformation |
| US6068994A (en) * | 1989-08-07 | 2000-05-30 | Chiron Corporation | Ubiquitin expression system |
| FR2660509B1 (fr) * | 1990-03-29 | 1993-11-19 | Alcatel Cit | Etage differentiel de sortie d'equipement electronique. |
| US5012652A (en) * | 1990-09-21 | 1991-05-07 | Carrier Corporation | Crankcase heater control for hermetic refrigerant compressors |
| US5134119A (en) * | 1990-10-16 | 1992-07-28 | Lezdey John | Treatment of inflammation using 358 substituted alpha-antitrypsin |
| US5268384A (en) * | 1990-11-21 | 1993-12-07 | Galardy Richard E | Inhibition of angiogenesis by synthetic matrix metalloprotease inhibitors |
| US5114953A (en) * | 1990-11-21 | 1992-05-19 | University Of Florida | Treatment for tissue ulceration |
| US5892112A (en) * | 1990-11-21 | 1999-04-06 | Glycomed Incorporated | Process for preparing synthetic matrix metalloprotease inhibitors |
| US5256657A (en) * | 1991-08-19 | 1993-10-26 | Sterling Winthrop, Inc. | Succinamide derivative matrix-metalloprotease inhibitors |
| TW282490B (https=) * | 1992-12-15 | 1996-08-01 | Ciba Geigy Ag | |
| US5594106A (en) * | 1993-08-23 | 1997-01-14 | Immunex Corporation | Inhibitors of TNF-α secretion |
| JP3779728B2 (ja) * | 1994-08-05 | 2006-05-31 | カイロン コーポレイション | 組織因子活性インヒビターの産生 |
| US5780014A (en) * | 1995-04-14 | 1998-07-14 | Inhale Therapeutic Systems | Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin |
| US6267958B1 (en) * | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
| US5780440A (en) * | 1996-06-17 | 1998-07-14 | Protease Sciences Inc. | Treatment of pulmonary disease with protease inhibitors |
| US6610683B2 (en) * | 1996-09-12 | 2003-08-26 | Idun Pharmaceuticals, Inc. | Treatment of infectious disease using interleukin-1β-converting enzyme (ICE)/CED-3 family inhibitors |
| EP0852951A1 (de) * | 1996-11-19 | 1998-07-15 | Roche Diagnostics GmbH | Stabile lyophilisierte pharmazeutische Zubereitungen von mono- oder polyklonalen Antikörpern |
| EP1659173A1 (en) * | 1997-10-01 | 2006-05-24 | DSMIP Assets B.V. | Protein production process |
| US20010006939A1 (en) * | 1997-10-03 | 2001-07-05 | Ralph W. Niven | Secretory leukocyte protease inhibitor dry powder pharmaceutical compositions |
| US5972986A (en) * | 1997-10-14 | 1999-10-26 | G.D. Searle & Co. | Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia |
| WO1999032135A1 (en) * | 1997-12-22 | 1999-07-01 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 formulations |
| WO1999032150A1 (en) * | 1997-12-23 | 1999-07-01 | Warner-Lambert Company | Ace inhibitor-mmp inhibitor combinations |
| JP2000247903A (ja) * | 1999-03-01 | 2000-09-12 | Chugai Pharmaceut Co Ltd | 長期安定化製剤 |
| WO2000051623A2 (en) * | 1999-03-05 | 2000-09-08 | The Trustees Of University Technology Corporation | Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide-induced clinical conditions |
| EE200200426A (et) * | 2000-01-31 | 2003-12-15 | Pfizer Products Inc. | PDE4 isosüümide inhibiitoritena kasulikud pürimidiinkarboksamiidid |
| GB0008660D0 (en) * | 2000-04-07 | 2000-05-31 | Arakis Ltd | The treatment of respiratory diseases |
| US6991824B2 (en) * | 2000-05-02 | 2006-01-31 | Ventria Bioscience | Expression of human milk proteins in transgenic plants |
| US20020099013A1 (en) * | 2000-11-14 | 2002-07-25 | Thomas Piccariello | Active agent delivery systems and methods for protecting and administering active agents |
| US7247704B2 (en) * | 2000-12-18 | 2007-07-24 | Arriva Pharmaceuticals, Inc. | Multifunctional protease inhibitors and their use in treatment of disease |
| PA8539301A1 (es) * | 2001-02-14 | 2002-09-30 | Warner Lambert Co | Inhibidores de la metaloproteinasa de la matriz |
| US6544497B2 (en) * | 2001-02-15 | 2003-04-08 | Aeropharm Technology Incorporated | Modulated release particles for aerosol delivery |
| JP2003024076A (ja) * | 2001-07-12 | 2003-01-28 | Kirin Brewery Co Ltd | Tpo変異体タンパク質 |
| FR2832569B1 (fr) * | 2001-11-22 | 2007-04-27 | Evolium Sas | Procede de transmission de communications dans un systeme de telecommunication de type cellulaire utilisant des bandes de frequences porteuses adjacentes |
| US20030211548A1 (en) * | 2002-01-29 | 2003-11-13 | Oncolmmunin, Inc. | Visualization and quantitiation of cellular cytotoxicity using cell-permeable fluorogenic protease substrates and caspase activity indicator markers |
| CA2545458A1 (en) * | 2003-11-10 | 2005-05-26 | Arriva-Prometic Inc. | Dry recombinant human alpha 1-antitrypsin formulation |
-
2004
- 2004-11-11 JP JP2006540034A patent/JP2007511539A/ja active Pending
- 2004-11-11 ES ES04811377T patent/ES2375706T3/es not_active Expired - Lifetime
- 2004-11-11 AU AU2004290587A patent/AU2004290587B2/en not_active Ceased
- 2004-11-11 PL PL04811377T patent/PL1684719T3/pl unknown
- 2004-11-11 CA CA002545855A patent/CA2545855A1/en not_active Abandoned
- 2004-11-11 PT PT04811377T patent/PT1684719E/pt unknown
- 2004-11-11 WO PCT/US2004/038650 patent/WO2005048985A2/en not_active Ceased
- 2004-11-11 EP EP04811377A patent/EP1684719B1/en not_active Expired - Lifetime
- 2004-11-11 DK DK04811377.3T patent/DK1684719T3/da active
- 2004-11-11 SI SI200431814T patent/SI1684719T1/sl unknown
- 2004-11-11 AT AT04811377T patent/ATE530165T1/de active
- 2004-11-11 US US10/579,088 patent/US20080312136A1/en not_active Abandoned
-
2010
- 2010-02-26 US US12/714,432 patent/US20100286066A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2007511539A5 (https=) | ||
| ES2664624T3 (es) | Alfa-I antitripsina para tratar episodios de exacerbación de enfermedades pulmonares | |
| CA1327309C (en) | Aerosolization of protein therapeutic agent | |
| JP4338214B2 (ja) | エリトロポエチンの肺投与 | |
| JP2024170583A5 (https=) | ||
| US20020127188A1 (en) | Composition for pulmonary administration comprising a drug and a hydrophobic amino acid | |
| AU2017298202A1 (en) | Methods for treating cystic fibrosis and other diseases affecting mucosal surfaces | |
| Jin et al. | Pulmonary delivery of the Kv1. 3-blocking peptide HsTX1 [R14A] for the treatment of autoimmune diseases | |
| US11559498B2 (en) | Compositions and methods for in vivo lung and blood SNO repletion | |
| Ozer | Alternative applications for drug delivery: Nasal and pulmonary routes | |
| CN105832715A (zh) | 炎症调节剂用于治疗囊性纤维化和其他肺部疾病中的感染的用途 | |
| ES2928050T3 (es) | Peptidomimético de horquilla beta con actividad inhibidora de elastasa y formas de dosificación en aerosol del mismo | |
| JP2007528409A (ja) | プロテアーゼインヒビターの低用量吸入による慢性閉塞性肺疾患の処置 | |
| ES2791775B2 (es) | Formulaciones de epinefrina intranasal y metodos para el tratamiento de enfermedades | |
| CN116234563A (zh) | 抗致病治疗方法 | |
| JP2009521473A5 (https=) | ||
| JP2007511539A (ja) | α1−抗トリプシン組成物およびこのような組成物を用いた処置方法 | |
| KR20220137051A (ko) | 염증성 폐질환의 흡입치료용 5-아미노-2,3-디히드로-1,4-프탈라진디온 | |
| IT202000005026A1 (it) | Lattoferrina per uso inalatorio ad azione antivirale | |
| US20070049641A1 (en) | Methods for treating and monitoring inflammation and redox imbalance cystic fibrosis | |
| CN103841958A (zh) | 组合物 | |
| Kwok et al. | Pulmonary delivery of peptides and proteins | |
| CN102348465A (zh) | 慢性阻塞性肺疾病改善剂 | |
| US20240009227A1 (en) | Use of a heparin composition in the treatment of viral lung diseases, acute and/or chronic lung diseases by soft mist inhaler or vibration mesh technology nebulizer through inhalation route | |
| CN105764488A (zh) | 用于向受试者的气道施用酶的组合物和方法 |