PT1684719E - Composições de alfa-1-antitripsina e métodos de tratamento utilizando estas composições - Google Patents

Composições de alfa-1-antitripsina e métodos de tratamento utilizando estas composições Download PDF

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Publication number
PT1684719E
PT1684719E PT04811377T PT04811377T PT1684719E PT 1684719 E PT1684719 E PT 1684719E PT 04811377 T PT04811377 T PT 04811377T PT 04811377 T PT04811377 T PT 04811377T PT 1684719 E PT1684719 E PT 1684719E
Authority
PT
Portugal
Prior art keywords
aat
composition
alpha
formulations
concentration
Prior art date
Application number
PT04811377T
Other languages
English (en)
Portuguese (pt)
Inventor
Manzer J Durrani
Harish Kumar
Timothy Kreiger
Ken Kabingue
Virginia Mosher
Philip J Barr
Ian C Bathurst
Original Assignee
Baxter Int
Arriva Pharmaceuticals Inc
Baxter Healthcare Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int, Arriva Pharmaceuticals Inc, Baxter Healthcare Sa filed Critical Baxter Int
Publication of PT1684719E publication Critical patent/PT1684719E/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8125—Alpha-1-antitrypsin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Otolaryngology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
PT04811377T 2003-11-14 2004-11-11 Composições de alfa-1-antitripsina e métodos de tratamento utilizando estas composições PT1684719E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52054903P 2003-11-14 2003-11-14

Publications (1)

Publication Number Publication Date
PT1684719E true PT1684719E (pt) 2012-02-03

Family

ID=34619481

Family Applications (1)

Application Number Title Priority Date Filing Date
PT04811377T PT1684719E (pt) 2003-11-14 2004-11-11 Composições de alfa-1-antitripsina e métodos de tratamento utilizando estas composições

Country Status (12)

Country Link
US (2) US20080312136A1 (https=)
EP (1) EP1684719B1 (https=)
JP (1) JP2007511539A (https=)
AT (1) ATE530165T1 (https=)
AU (1) AU2004290587B2 (https=)
CA (1) CA2545855A1 (https=)
DK (1) DK1684719T3 (https=)
ES (1) ES2375706T3 (https=)
PL (1) PL1684719T3 (https=)
PT (1) PT1684719E (https=)
SI (1) SI1684719T1 (https=)
WO (1) WO2005048985A2 (https=)

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AU2010315325B2 (en) 2009-11-03 2014-11-27 Grifols Therapeutics Inc. Composition, method, and kit for alpha-1 proteinase inhibitor
PT2503995T (pt) 2009-11-24 2017-11-23 Grifols Therapeutics Inc Métodos de liofilização, composições e kits
RU2581020C2 (ru) * 2009-12-22 2016-04-10 Селлдекс Терапьютикс, Инк. Композиции вакцин
KR20140108516A (ko) 2011-12-30 2014-09-11 그리폴스, 에스.에이. 폐 악화의 발현 또는 진행을 지연시키기 위한 알파1-프로테이나제 억제제
EP2978442B1 (en) * 2013-03-29 2020-03-18 The Regents of the University of Colorado, a body corporate Alpha 1 antitrypsin of use for preparing a subject for transplant
EP3155117A4 (en) * 2014-06-11 2017-11-22 Beth Israel Deaconess Medical Center, Inc. Alpha1-antitrypsin compositions and methods of treating autoimmune diseases
WO2018116300A1 (en) * 2016-12-22 2018-06-28 Kamada Ltd. Dry powder formulations of alpha-1 antitrypsin
WO2018154568A1 (en) * 2017-02-21 2018-08-30 Kamada Ltd. Methods and uses of alpha 1-antitrypsin for early intervention in pulmonary diseases
EP3600345A4 (en) 2017-03-29 2021-01-06 Cornell University OXIDATION-RESISTANT AAT GENE THERAPY
CA3081161A1 (en) * 2017-10-31 2019-05-09 Kamada Ltd Methods and compositions for reducing lung injury associated with lung transplantation
IL267923B2 (en) * 2018-08-02 2023-06-01 Grifols Worldwide Operations Ltd The composition containing the most concentrated alpha-1 type protein inhibitor and a method for obtaining it
CA3117213A1 (en) * 2018-10-23 2020-04-30 George Edward Hoag Composition and method for treating the lungs
EP3921334A1 (en) 2019-02-08 2021-12-15 Krystal Biotech, Inc. Compositions and methods for delivering cftr polypeptides
CA3160199A1 (en) * 2019-12-20 2021-06-24 Suma Krishnan Compositions and methods for gene delivery to the airways and/or lungs
GB202102258D0 (en) * 2021-02-17 2021-03-31 Arecor Ltd Novel composition

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Also Published As

Publication number Publication date
DK1684719T3 (da) 2012-01-30
WO2005048985A2 (en) 2005-06-02
ATE530165T1 (de) 2011-11-15
SI1684719T1 (sl) 2012-07-31
JP2007511539A (ja) 2007-05-10
EP1684719A2 (en) 2006-08-02
US20080312136A1 (en) 2008-12-18
AU2004290587B2 (en) 2010-08-12
US20100286066A1 (en) 2010-11-11
WO2005048985A3 (en) 2006-03-23
ES2375706T3 (es) 2012-03-05
EP1684719B1 (en) 2011-10-26
CA2545855A1 (en) 2005-06-02
PL1684719T3 (pl) 2012-11-30
AU2004290587A1 (en) 2005-06-02

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