JP2007511297A5 - - Google Patents
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- JP2007511297A5 JP2007511297A5 JP2006540021A JP2006540021A JP2007511297A5 JP 2007511297 A5 JP2007511297 A5 JP 2007511297A5 JP 2006540021 A JP2006540021 A JP 2006540021A JP 2006540021 A JP2006540021 A JP 2006540021A JP 2007511297 A5 JP2007511297 A5 JP 2007511297A5
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- Prior art keywords
- flow path
- tei
- valve
- drug formulation
- aerosol introducer
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- 239000000443 aerosol Substances 0.000 claims 21
- 239000003814 drug Substances 0.000 claims 13
- 229940079593 drugs Drugs 0.000 claims 13
- 238000009472 formulation Methods 0.000 claims 13
- 239000000203 mixture Substances 0.000 claims 13
- 239000006199 nebulizer Substances 0.000 claims 11
- 230000003434 inspiratory Effects 0.000 claims 3
- CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 claims 1
- 210000001331 Nose Anatomy 0.000 claims 1
- MYPYJXKWCTUITO-LYRMYLQWSA-N VANCOMYCIN Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 claims 1
- 229960003165 Vancomycin Drugs 0.000 claims 1
- 108010059993 Vancomycin Proteins 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 230000003115 biocidal Effects 0.000 claims 1
- 229960002518 gentamicin Drugs 0.000 claims 1
Claims (27)
- エアロゾル化薬剤調合物を、人工呼吸器循環路内に導入するためのエアロゾル導入器であって、
該人工呼吸器循環路は、気管内チューブと、該人工呼吸器から延びる吸気ラインと、該人工呼吸器から延びる呼気ラインとを含み;
該エアロゾル導入器は、
該吸気ライン及び該呼気ラインに接続可能な第一端;
該気管内チューブに接続可能な第二端;
該第一端から該第二端へ延びる第一の流路;
該第一端から該第二端へ延びる第二の流路;
エアロゾル化薬剤調合物を受け入れるのに適している、該第一の流路内のインレット;及び
該呼気ラインへのエアロゾル化薬剤調合物の損失を減らす一つ又は二つ以上のバルブを含むバルブ機構:を含んで成る。 - 該バルブ機構が、該第一の流路内に配置されている逆止弁を含む、請求項1に記載のエアロゾル導入器。
- 該バルブ機構が、該第二の流路内に配置されている逆止弁を含む、請求項1に記載のエアロゾル導入器。
- 該バルブ機構が、該第一の流路内に配置されている逆止弁と、該第二の流路内に配置されている逆止弁とを含む、請求項1に記載のエアロゾル導入器。
- 該インレットがネブライザに接続されている、請求項1に記載のエアロゾル導入器。
- 該ネブライザがジェットネブライザである、請求項5に記載のエアロゾル導入器。
- 該ネブライザが振動するメッシュを含む、請求項5に記載のエアロゾル導入器。
- 該第一端が、該吸気ラインと該呼気ラインとに取付けられているY字形ピースに接続可能である、請求項1に記載のエアロゾル導入器。
- 該第一端が、該吸気ラインへの接続用の第一のコネクタと、該呼気ラインへの接続用の第二のコネクタとを含む、請求項1に記載のエアロゾル導入器。
- 該第二端が軟質チューブを含む、請求項1に記載のエアロゾル導入器。
- エアロゾル化薬剤調合物を患者に送達させるためのエアロゾル導入器であって;
第一端;
ユーザの口又は鼻にエアロゾルを送達させる開口部を含む第二端;
該第一端から該第二端へ延びる第一の流路;
該第一端から該第二端へ延びる第二の流路;
エアロゾル化薬剤調合物を受け入れるのに適している、該第一の流路内のインレット;及び
該第一又は第二の流路内のバルブ:を含むエアロゾル導入器。 - 該バルブが、該第一の流路内に配置されている逆止弁を含む、請求項11に記載のエアロゾル導入器。
- 該バルブが、該第二の流路内に配置されている逆止弁を含む、請求項11に記載のエアロゾル導入器。
- 該バルブが、該第一の流路内に配置されている逆止弁を含み、そして該第二の流路内に配置されている逆止弁をさらに含む、請求項11に記載のエアロゾル導入器。
- 該インレットがネブライザに接続されている、請求項11に記載のエアロゾル導入器。
- 該ネブライザがジェットネブライザである、請求項15に記載のエアロゾル導入器。
- 該ネブライザが振動するメッシュを含む、請求項15に記載のエアロゾル導入器。
- エアロゾル化薬剤調合物の人工呼吸器循環路内への導入方法であって、
第一端、第二端、該第一端から該第二端へ延びる第一の流路、該第一端から該第二端へ延びる第二の流路、該第一の流路内のインレット、並びに該第一及び/又は第二の流路内のバルブを含むエアロゾル導入器を準備する段階;
該第一端を人工呼吸器から延びる吸気ライン及び呼気ラインに接続する段階;
該第二端を気管内チューブに接続する段階;そして
該インレットを介して、該第一の流路内にエアロゾル化該薬剤調合物を受け入れる段階:を含む導入方法。 - 該バルブが、該第一の流路内に配置されている逆止弁を含む、請求項18に記載の方法。
- 該バルブが、該第二の流路内に配置されている逆止弁を含む、請求項18に記載の方法。
- 該バルブが、該第一の流路内に配置されている逆止弁であり、そして該第二の流路内に配置されている逆止弁をさらに含む、請求項18に記載の方法。
- 該エアロゾル化薬剤調合物をネブライザから受け入れる、請求項18に記載の方法。
- 該エアロゾル化薬剤調合物をジェットネブライザから受け入れる、請求項18に記載の方法。
- 該エアロゾル化薬剤調合物をメッシュ振動式ネブライザから受け入れる、請求項18に記載の方法。
- 該エアロゾル化薬剤調合物が抗生物質を含む、請求項18に記載の方法。
- 該エアロゾル化薬剤調合物がバンコマイシンを含む、請求項18に記載の方法。
- 該エアロゾル化薬剤調合物がゲンタマイシンを含む、請求項18に記載の方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52301103P | 2003-11-17 | 2003-11-17 | |
US60/523,011 | 2003-11-17 | ||
PCT/US2004/038503 WO2005048982A2 (en) | 2003-11-17 | 2004-11-17 | Efficient introduction of an aerosol into a ventilator circuit |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2007511297A JP2007511297A (ja) | 2007-05-10 |
JP2007511297A5 true JP2007511297A5 (ja) | 2007-12-20 |
JP4933262B2 JP4933262B2 (ja) | 2012-05-16 |
Family
ID=34619556
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006540021A Expired - Fee Related JP4933262B2 (ja) | 2003-11-17 | 2004-11-17 | 人工呼吸器循環路へのエアロゾル導入 |
Country Status (11)
Country | Link |
---|---|
US (1) | US8375947B2 (ja) |
EP (1) | EP1684720B1 (ja) |
JP (1) | JP4933262B2 (ja) |
KR (1) | KR101137052B1 (ja) |
AT (1) | ATE432064T1 (ja) |
AU (1) | AU2004291172B2 (ja) |
BR (1) | BRPI0416654A (ja) |
CA (1) | CA2545219C (ja) |
DE (1) | DE602004021279D1 (ja) |
ES (1) | ES2327935T3 (ja) |
WO (1) | WO2005048982A2 (ja) |
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2004
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- 2004-11-17 AT AT04819171T patent/ATE432064T1/de active
- 2004-11-17 BR BRPI0416654-0A patent/BRPI0416654A/pt not_active Application Discontinuation
- 2004-11-17 US US10/991,092 patent/US8375947B2/en active Active
- 2004-11-17 AU AU2004291172A patent/AU2004291172B2/en not_active Ceased
- 2004-11-17 ES ES04819171T patent/ES2327935T3/es active Active
- 2004-11-17 KR KR1020067011606A patent/KR101137052B1/ko active IP Right Grant
- 2004-11-17 WO PCT/US2004/038503 patent/WO2005048982A2/en active Application Filing
- 2004-11-17 EP EP04819171A patent/EP1684720B1/en active Active
- 2004-11-17 DE DE602004021279T patent/DE602004021279D1/de active Active
- 2004-11-17 CA CA2545219A patent/CA2545219C/en not_active Expired - Fee Related
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