JP2007510619A5 - - Google Patents

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Publication number
JP2007510619A5
JP2007510619A5 JP2006518489A JP2006518489A JP2007510619A5 JP 2007510619 A5 JP2007510619 A5 JP 2007510619A5 JP 2006518489 A JP2006518489 A JP 2006518489A JP 2006518489 A JP2006518489 A JP 2006518489A JP 2007510619 A5 JP2007510619 A5 JP 2007510619A5
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JP
Japan
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independently represent
chf
substituent
compound
formula
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JP2006518489A
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English (en)
Japanese (ja)
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JP2007510619A (ja
JP4636021B2 (ja
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Priority claimed from PCT/JP2004/016469 external-priority patent/WO2005042533A2/en
Publication of JP2007510619A publication Critical patent/JP2007510619A/ja
Publication of JP2007510619A5 publication Critical patent/JP2007510619A5/ja
Application granted granted Critical
Publication of JP4636021B2 publication Critical patent/JP4636021B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2006518489A 2003-10-31 2004-10-29 2−シアノピロリジンカルボキシアミド化合物 Expired - Fee Related JP4636021B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2003906010A AU2003906010A0 (en) 2003-10-31 DPP-IV Inhibitor
AU2004900961A AU2004900961A0 (en) 2004-02-25 DPP-IV inhibitor
PCT/JP2004/016469 WO2005042533A2 (en) 2003-10-31 2004-10-29 2-cyanopyrrolidinecarboxamides as dipeptidyl peptidase-iv inhibitors

Publications (3)

Publication Number Publication Date
JP2007510619A JP2007510619A (ja) 2007-04-26
JP2007510619A5 true JP2007510619A5 (enExample) 2007-11-29
JP4636021B2 JP4636021B2 (ja) 2011-02-23

Family

ID=34553068

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006518489A Expired - Fee Related JP4636021B2 (ja) 2003-10-31 2004-10-29 2−シアノピロリジンカルボキシアミド化合物

Country Status (17)

Country Link
US (1) US7186731B2 (enExample)
EP (1) EP1737863B1 (enExample)
JP (1) JP4636021B2 (enExample)
KR (1) KR20060100390A (enExample)
AR (1) AR046313A1 (enExample)
AT (1) ATE419250T1 (enExample)
BR (1) BRPI0415587A (enExample)
CA (1) CA2543533A1 (enExample)
CO (1) CO5690603A2 (enExample)
DE (1) DE602004018837D1 (enExample)
ES (1) ES2320557T3 (enExample)
IL (1) IL175214A0 (enExample)
MX (1) MXPA06004797A (enExample)
NO (1) NO20062517L (enExample)
RU (1) RU2006118789A (enExample)
TW (1) TW200528440A (enExample)
WO (1) WO2005042533A2 (enExample)

Families Citing this family (32)

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EA011086B9 (ru) 2004-05-12 2012-08-30 Пфайзер Продактс Инк. Производные пролина и их применение в качестве ингибиторов дипептидилпептидазы iv
US20060199853A1 (en) * 2005-02-18 2006-09-07 Charles Mioskowski Analogs of 4-hydroxyisoleucine and uses thereof
EP1874287A2 (en) * 2005-03-22 2008-01-09 Innodia Inc. Compounds and compositions for use in the prevention and treatment of obesity and related syndromes
MX2007011453A (es) 2005-04-22 2008-02-12 Alantos Pharmaceuticals Holding Inc Inhibidores de la dipeptidil peptidasa-iv.
WO2007017423A2 (en) * 2005-08-11 2007-02-15 F. Hoffmann-La Roche Ag Pharmaceutical composition comprising a dpp-iv inhibitor
GB0526291D0 (en) 2005-12-23 2006-02-01 Prosidion Ltd Therapeutic method
WO2007107008A1 (en) * 2006-03-22 2007-09-27 Innodia Inc. Compounds and compositions for use in the prevention and treatment of disorders of fat metabolism and obesity
PE20071221A1 (es) 2006-04-11 2007-12-14 Arena Pharm Inc Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
US7727978B2 (en) * 2006-08-24 2010-06-01 Bristol-Myers Squibb Company Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors
GB0713602D0 (en) * 2007-07-12 2007-08-22 Syngenta Participations Ag Chemical compounds
GB2465132B (en) * 2007-09-21 2012-06-06 Lupin Ltd Compounds as dipeptidyl peptidase IV (DPP IV) inhibitors
JP5305704B2 (ja) * 2008-03-24 2013-10-02 富士フイルム株式会社 新規化合物、光重合性組成物、カラーフィルタ用光重合性組成物、カラーフィルタ、及びその製造方法、固体撮像素子、並びに、平版印刷版原版
EP2146210A1 (en) 2008-04-07 2010-01-20 Arena Pharmaceuticals, Inc. Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditions modulated by PYY
GB2483614B (en) 2009-06-18 2014-12-03 Lupin Ltd 2-Amino-2- [8-(dimethyl carbamoyl)- 8-aza- bicyclo [3.2.1] oct-3-yl]-exo- ethanoyl derivatives as potent dpp-iv inhibitors
US8999975B2 (en) 2011-09-19 2015-04-07 Boehringer Ingelheim International Gmbh Substituted N- [1-cyano-2- (phenyl) ethyl] -2-azabicyclo [2.2.1] heptane-3-carboxamide inhibitors of cathepsin C
EA030003B1 (ru) 2012-12-21 2018-06-29 Джилид Сайэнс, Инк. Полициклическое карбамоилпиридоновое соединение и его фармацевтическое применение для лечения вич-инфекции
EA029052B1 (ru) 2013-03-14 2018-02-28 Бёрингер Ингельхайм Интернациональ Гмбх Замещенные (бензилцианометил)амиды 2-азабицикло[2.2.1]гептан-3-карбоновых кислот в качестве ингибиторов катепсина с
EP2970252B1 (en) 2013-03-14 2020-06-03 Boehringer Ingelheim International GmbH Substituted 2-aza-bicyclo[2.2.2]octane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin c
DK3019503T3 (da) 2013-07-12 2017-11-20 Gilead Sciences Inc Polycykliske-carbamoylpyridon-forbindelser og anvendelse deraf til behandling af hiv-infektioner
NO2865735T3 (enExample) 2013-07-12 2018-07-21
TW201613936A (en) 2014-06-20 2016-04-16 Gilead Sciences Inc Crystalline forms of(2R,5S,13aR)-8-hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
TWI744723B (zh) 2014-06-20 2021-11-01 美商基利科學股份有限公司 多環型胺甲醯基吡啶酮化合物之合成
NO2717902T3 (enExample) 2014-06-20 2018-06-23
WO2016016242A1 (en) 2014-08-01 2016-02-04 Boehringer Ingelheim International Gmbh Substituted oxetanes and their use as inhibitors of cathepsin c
HUE047208T2 (hu) 2014-09-12 2020-04-28 Boehringer Ingelheim Int A katepszin-C spirociklikus inhibitorai
TWI695003B (zh) 2014-12-23 2020-06-01 美商基利科學股份有限公司 多環胺甲醯基吡啶酮化合物及其醫藥用途
CN107683135A (zh) 2015-03-09 2018-02-09 因特克林医疗有限公司 用于治疗非酒精性脂肪肝疾病和/或脂肪营养不良的方法
CA2980362C (en) 2015-04-02 2020-02-25 Gilead Sciences, Inc. Polycyclic-carbamoylpyridone compounds and their pharmaceutical use
AU2018249822A1 (en) 2017-04-03 2019-10-31 Coherus Biosciences Inc. PPArgamma agonist for treatment of progressive supranuclear palsy
IT201700059292A1 (it) 2017-05-31 2018-12-01 Univ Pisa Derivati 1,3-diaza-4-ossa-[3.3.1]-biciclici, loro preparazione e uso come medicinale, in particolare per il trattamento del diabete
US12662494B2 (en) 2018-08-08 2026-06-23 Sumitomo Pharma Co., Ltd. Optically active bridged piperidine derivative
TWI815954B (zh) 2018-08-27 2023-09-21 日商住友製藥股份有限公司 光學活性氮雜雙環衍生物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003057144A2 (en) * 2001-12-26 2003-07-17 Guilford Pharmaceuticals Change inhibitors of dipeptidyl peptidase iv
TW200401635A (en) * 2002-07-23 2004-02-01 Yamanouchi Pharma Co Ltd 2-Cyano-4-fluoropyrrolidine derivative or salt thereof

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