JP2007510619A5 - - Google Patents

Download PDF

Info

Publication number
JP2007510619A5
JP2007510619A5 JP2006518489A JP2006518489A JP2007510619A5 JP 2007510619 A5 JP2007510619 A5 JP 2007510619A5 JP 2006518489 A JP2006518489 A JP 2006518489A JP 2006518489 A JP2006518489 A JP 2006518489A JP 2007510619 A5 JP2007510619 A5 JP 2007510619A5
Authority
JP
Japan
Prior art keywords
independently represent
chf
substituent
compound
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2006518489A
Other languages
English (en)
Japanese (ja)
Other versions
JP4636021B2 (ja
JP2007510619A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/JP2004/016469 external-priority patent/WO2005042533A2/en
Publication of JP2007510619A publication Critical patent/JP2007510619A/ja
Publication of JP2007510619A5 publication Critical patent/JP2007510619A5/ja
Application granted granted Critical
Publication of JP4636021B2 publication Critical patent/JP4636021B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2006518489A 2003-10-31 2004-10-29 2−シアノピロリジンカルボキシアミド化合物 Expired - Fee Related JP4636021B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2003906010A AU2003906010A0 (en) 2003-10-31 DPP-IV Inhibitor
AU2004900961A AU2004900961A0 (en) 2004-02-25 DPP-IV inhibitor
PCT/JP2004/016469 WO2005042533A2 (en) 2003-10-31 2004-10-29 2-cyanopyrrolidinecarboxamides as dipeptidyl peptidase-iv inhibitors

Publications (3)

Publication Number Publication Date
JP2007510619A JP2007510619A (ja) 2007-04-26
JP2007510619A5 true JP2007510619A5 (enExample) 2007-11-29
JP4636021B2 JP4636021B2 (ja) 2011-02-23

Family

ID=34553068

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006518489A Expired - Fee Related JP4636021B2 (ja) 2003-10-31 2004-10-29 2−シアノピロリジンカルボキシアミド化合物

Country Status (17)

Country Link
US (1) US7186731B2 (enExample)
EP (1) EP1737863B1 (enExample)
JP (1) JP4636021B2 (enExample)
KR (1) KR20060100390A (enExample)
AR (1) AR046313A1 (enExample)
AT (1) ATE419250T1 (enExample)
BR (1) BRPI0415587A (enExample)
CA (1) CA2543533A1 (enExample)
CO (1) CO5690603A2 (enExample)
DE (1) DE602004018837D1 (enExample)
ES (1) ES2320557T3 (enExample)
IL (1) IL175214A0 (enExample)
MX (1) MXPA06004797A (enExample)
NO (1) NO20062517L (enExample)
RU (1) RU2006118789A (enExample)
TW (1) TW200528440A (enExample)
WO (1) WO2005042533A2 (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0510284A (pt) 2004-05-12 2007-10-30 Pfizer Prod Inc derivados de prolina e seu uso como inibidores da dipeptidil peptidase iv
CA2598365A1 (en) * 2005-02-18 2006-11-16 Innodia Inc. Analogs of 4-hydroxyisoleucine and uses thereof
CA2600954A1 (en) * 2005-03-22 2006-12-14 Innodia Inc. Compounds and compositions for use in the prevention and treatment of obesity and related syndromes
EP1888562B1 (en) 2005-04-22 2014-06-18 Alantos Pharmaceuticals Holding, Inc. Dipeptidyl peptidase-iv inhibitors
CA2617715A1 (en) * 2005-08-11 2007-02-15 F. Hoffmann-La Roche Ag Pharmaceutical composition comprising a dpp-iv inhibitor
GB0526291D0 (en) 2005-12-23 2006-02-01 Prosidion Ltd Therapeutic method
US20100048545A1 (en) * 2006-03-22 2010-02-25 Innodia Inc. Compounds and Compositions for Use in the Prevention and Treatment of Disorders of Fat Metabolism and Obesity
PE20071221A1 (es) 2006-04-11 2007-12-14 Arena Pharm Inc Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
US7727978B2 (en) * 2006-08-24 2010-06-01 Bristol-Myers Squibb Company Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors
GB0713602D0 (en) * 2007-07-12 2007-08-22 Syngenta Participations Ag Chemical compounds
GB2465132B (en) * 2007-09-21 2012-06-06 Lupin Ltd Compounds as dipeptidyl peptidase IV (DPP IV) inhibitors
JP5305704B2 (ja) * 2008-03-24 2013-10-02 富士フイルム株式会社 新規化合物、光重合性組成物、カラーフィルタ用光重合性組成物、カラーフィルタ、及びその製造方法、固体撮像素子、並びに、平版印刷版原版
EP2108960A1 (en) 2008-04-07 2009-10-14 Arena Pharmaceuticals, Inc. Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditons modulated by PYY
GB2483614B (en) 2009-06-18 2014-12-03 Lupin Ltd 2-Amino-2- [8-(dimethyl carbamoyl)- 8-aza- bicyclo [3.2.1] oct-3-yl]-exo- ethanoyl derivatives as potent dpp-iv inhibitors
US8999975B2 (en) * 2011-09-19 2015-04-07 Boehringer Ingelheim International Gmbh Substituted N- [1-cyano-2- (phenyl) ethyl] -2-azabicyclo [2.2.1] heptane-3-carboxamide inhibitors of cathepsin C
SI2822954T1 (sl) 2012-12-21 2016-07-29 Gilead Sciences, Inc. Policiklične karbamoilpiridonske spojine in njihova farmacevtska uporaba
GEP201706780B (en) 2013-03-14 2017-11-27 Boehringer Ingelheim Int Substituted 2-aza-bicyclo [2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin c
WO2014140091A1 (en) 2013-03-14 2014-09-18 Boehringer Ingelheim International Gmbh Substituted 2-aza-bicyclo[2.2.2]octane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin c
NO2865735T3 (enExample) 2013-07-12 2018-07-21
PT3019503T (pt) 2013-07-12 2017-11-27 Gilead Sciences Inc Compostos carbamoílpiridona- policíclicos e seu uso para o tratamento de infecções por hiv
TW201613936A (en) 2014-06-20 2016-04-16 Gilead Sciences Inc Crystalline forms of(2R,5S,13aR)-8-hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
NO2717902T3 (enExample) 2014-06-20 2018-06-23
TWI744723B (zh) 2014-06-20 2021-11-01 美商基利科學股份有限公司 多環型胺甲醯基吡啶酮化合物之合成
JP6529575B2 (ja) 2014-08-01 2019-06-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 置換オキセタンおよびそれらのカテプシンcの阻害薬としての使用
UA118610C2 (uk) 2014-09-12 2019-02-11 Бьорінгер Інгельхайм Інтернаціональ Гмбх Спіроциклічні інгібітори катепсину c
TWI695003B (zh) 2014-12-23 2020-06-01 美商基利科學股份有限公司 多環胺甲醯基吡啶酮化合物及其醫藥用途
MX386778B (es) 2015-03-09 2025-03-19 Intekrin Therapeutics Inc Métodos para el tratamiento de enfermedad de hígado graso no alcohólico y/o lipodistrofia.
WO2016161382A1 (en) 2015-04-02 2016-10-06 Gilead Sciences, Inc. Polycyclic-carbamoylpyridone compounds and their pharmaceutical use
WO2018187350A1 (en) 2017-04-03 2018-10-11 Coherus Biosciences Inc. PPARγ AGONIST FOR TREATMENT OF PROGRESSIVE SUPRANUCLEAR PALSY
IT201700059292A1 (it) 2017-05-31 2018-12-01 Univ Pisa Derivati 1,3-diaza-4-ossa-[3.3.1]-biciclici, loro preparazione e uso come medicinale, in particolare per il trattamento del diabete
US20210198283A1 (en) 2018-08-08 2021-07-01 Sumitomo Dainippon Pharma Co., Ltd. Optically active bridged piperidine derivative
EA202190623A1 (ru) 2018-08-27 2021-05-21 Сумитомо Дайниппон Фарма Ко., Лтд. Оптически активное азабициклическое производное

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003057144A2 (en) * 2001-12-26 2003-07-17 Guilford Pharmaceuticals Change inhibitors of dipeptidyl peptidase iv
TW200401635A (en) * 2002-07-23 2004-02-01 Yamanouchi Pharma Co Ltd 2-Cyano-4-fluoropyrrolidine derivative or salt thereof

Similar Documents

Publication Publication Date Title
JP2007510619A5 (enExample)
JP2003531118A5 (enExample)
JP2007500753A5 (enExample)
JP2005053931A5 (enExample)
JP2007522220A5 (enExample)
JP2007518682A5 (enExample)
JP2002332234A5 (enExample)
JP2005511547A5 (enExample)
JP2005538089A5 (enExample)
JP2005525294A5 (enExample)
JP2010536766A5 (enExample)
JP2007508362A5 (enExample)
JP2004516314A5 (enExample)
JP2006515626A5 (enExample)
JP2007505916A5 (enExample)
JP2002527414A5 (enExample)
JP2007519618A5 (enExample)
JP2007506721A5 (enExample)
JP2010507590A5 (enExample)
JP2008520662A5 (enExample)
JP2006518752A5 (enExample)
JP2007532575A5 (enExample)
JP2009501704A5 (enExample)
JP2006518765A5 (enExample)
JP2004538278A5 (enExample)