JP2007510619A5 - - Google Patents

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Publication number
JP2007510619A5
JP2007510619A5 JP2006518489A JP2006518489A JP2007510619A5 JP 2007510619 A5 JP2007510619 A5 JP 2007510619A5 JP 2006518489 A JP2006518489 A JP 2006518489A JP 2006518489 A JP2006518489 A JP 2006518489A JP 2007510619 A5 JP2007510619 A5 JP 2007510619A5
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JP
Japan
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chf
substituent
compound
formula
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JP2006518489A
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English (en)
Japanese (ja)
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JP4636021B2 (ja
JP2007510619A (ja
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Priority claimed from PCT/JP2004/016469 external-priority patent/WO2005042533A2/en
Publication of JP2007510619A publication Critical patent/JP2007510619A/ja
Publication of JP2007510619A5 publication Critical patent/JP2007510619A5/ja
Application granted granted Critical
Publication of JP4636021B2 publication Critical patent/JP4636021B2/ja
Expired - Fee Related legal-status Critical Current
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JP2006518489A 2003-10-31 2004-10-29 2−シアノピロリジンカルボキシアミド化合物 Expired - Fee Related JP4636021B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2003906010A AU2003906010A0 (en) 2003-10-31 DPP-IV Inhibitor
AU2004900961A AU2004900961A0 (en) 2004-02-25 DPP-IV inhibitor
PCT/JP2004/016469 WO2005042533A2 (en) 2003-10-31 2004-10-29 2-cyanopyrrolidinecarboxamides as dipeptidyl peptidase-iv inhibitors

Publications (3)

Publication Number Publication Date
JP2007510619A JP2007510619A (ja) 2007-04-26
JP2007510619A5 true JP2007510619A5 (US06894165-20050517-C00155.png) 2007-11-29
JP4636021B2 JP4636021B2 (ja) 2011-02-23

Family

ID=34553068

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006518489A Expired - Fee Related JP4636021B2 (ja) 2003-10-31 2004-10-29 2−シアノピロリジンカルボキシアミド化合物

Country Status (17)

Country Link
US (1) US7186731B2 (US06894165-20050517-C00155.png)
EP (1) EP1737863B1 (US06894165-20050517-C00155.png)
JP (1) JP4636021B2 (US06894165-20050517-C00155.png)
KR (1) KR20060100390A (US06894165-20050517-C00155.png)
AR (1) AR046313A1 (US06894165-20050517-C00155.png)
AT (1) ATE419250T1 (US06894165-20050517-C00155.png)
BR (1) BRPI0415587A (US06894165-20050517-C00155.png)
CA (1) CA2543533A1 (US06894165-20050517-C00155.png)
CO (1) CO5690603A2 (US06894165-20050517-C00155.png)
DE (1) DE602004018837D1 (US06894165-20050517-C00155.png)
ES (1) ES2320557T3 (US06894165-20050517-C00155.png)
IL (1) IL175214A0 (US06894165-20050517-C00155.png)
MX (1) MXPA06004797A (US06894165-20050517-C00155.png)
NO (1) NO20062517L (US06894165-20050517-C00155.png)
RU (1) RU2006118789A (US06894165-20050517-C00155.png)
TW (1) TW200528440A (US06894165-20050517-C00155.png)
WO (1) WO2005042533A2 (US06894165-20050517-C00155.png)

Families Citing this family (32)

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Publication number Priority date Publication date Assignee Title
ATE437870T1 (de) 2004-05-12 2009-08-15 Pfizer Prod Inc Prolinderivate und deren verwendung als dipeptidylpeptidase-iv-inhibitoren
CN101193852A (zh) * 2005-02-18 2008-06-04 因诺迪亚有限公司 4-羟基异亮氨酸类似物及其用途
WO2006131836A2 (en) * 2005-03-22 2006-12-14 Innodia Inc. Compounds and compositions for use in the prevention and treatment of obesity and related syndromes
WO2006116157A2 (en) 2005-04-22 2006-11-02 Alantos Pharmaceuticals Holding, Inc. Dipeptidyl peptidase-iv inhibitors
JP2009504599A (ja) * 2005-08-11 2009-02-05 エフ.ホフマン−ラ ロシュ アーゲー Dpp−iv阻害剤を含有する医薬組成物
GB0526291D0 (en) 2005-12-23 2006-02-01 Prosidion Ltd Therapeutic method
WO2007107008A1 (en) * 2006-03-22 2007-09-27 Innodia Inc. Compounds and compositions for use in the prevention and treatment of disorders of fat metabolism and obesity
PE20071221A1 (es) 2006-04-11 2007-12-14 Arena Pharm Inc Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
US7727978B2 (en) * 2006-08-24 2010-06-01 Bristol-Myers Squibb Company Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors
GB0713602D0 (en) * 2007-07-12 2007-08-22 Syngenta Participations Ag Chemical compounds
WO2009037719A1 (en) * 2007-09-21 2009-03-26 Lupin Limited Novel compounds as dipeptidyl peptidase iv (dpp iv) inhibitors
JP5305704B2 (ja) * 2008-03-24 2013-10-02 富士フイルム株式会社 新規化合物、光重合性組成物、カラーフィルタ用光重合性組成物、カラーフィルタ、及びその製造方法、固体撮像素子、並びに、平版印刷版原版
EP2146210A1 (en) 2008-04-07 2010-01-20 Arena Pharmaceuticals, Inc. Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditions modulated by PYY
US8748457B2 (en) 2009-06-18 2014-06-10 Lupin Limited 2-amino-2- [8-(dimethyl carbamoyl)- 8-aza- bicyclo [3.2.1] oct-3-yl]-exo- ethanoyl derivatives as potent DPP-IV inhibitors
US8999975B2 (en) * 2011-09-19 2015-04-07 Boehringer Ingelheim International Gmbh Substituted N- [1-cyano-2- (phenyl) ethyl] -2-azabicyclo [2.2.1] heptane-3-carboxamide inhibitors of cathepsin C
MD4841B1 (ro) 2012-12-21 2023-01-31 Gilead Sciences, Inc. Compuşi policiclici de carbamoilpiridonă şi utilizarea lor farmaceutică
ES2845473T3 (es) 2013-03-14 2021-07-26 Boehringer Ingelheim Int (Bencil-ciano-metil)-amidas sustituidas de ácido 2-aza-biciclo[2.2.1]heptano-3-carboxílico inhibidores de la catepsina- C
US8877775B2 (en) 2013-03-14 2014-11-04 Boehringer Ingelheim International Gmbh Substituted 2-aza-bicyclo[2.2.2]octane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin C
NO2865735T3 (US06894165-20050517-C00155.png) 2013-07-12 2018-07-21
EP3252058B1 (en) 2013-07-12 2021-01-20 Gilead Sciences, Inc. Polycyclic-carbamoylpyridone compounds and their use for the treatment of hiv infections
NO2717902T3 (US06894165-20050517-C00155.png) 2014-06-20 2018-06-23
TWI744723B (zh) 2014-06-20 2021-11-01 美商基利科學股份有限公司 多環型胺甲醯基吡啶酮化合物之合成
TW201613936A (en) 2014-06-20 2016-04-16 Gilead Sciences Inc Crystalline forms of(2R,5S,13aR)-8-hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
JP6529575B2 (ja) 2014-08-01 2019-06-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 置換オキセタンおよびそれらのカテプシンcの阻害薬としての使用
WO2016038007A1 (en) 2014-09-12 2016-03-17 Boehringer Ingelheim International Gmbh Spirocyclic inhibitors of cathepsin c
TWI738321B (zh) 2014-12-23 2021-09-01 美商基利科學股份有限公司 多環胺甲醯基吡啶酮化合物及其醫藥用途
EA201791982A1 (ru) 2015-03-09 2020-02-17 Интекрин Терапьютикс, Инк. Способы лечения неалкогольной жировой болезни печени и/или липодистрофии
SG11201707905WA (en) 2015-04-02 2017-10-30 Gilead Sciences Inc Polycyclic-carbamoylpyridone compounds and their pharmaceutical use
EP3606527A1 (en) 2017-04-03 2020-02-12 Coherus Biosciences, Inc. Ppar-gamma agonist for treatment of progressive supranuclear palsy
IT201700059292A1 (it) * 2017-05-31 2018-12-01 Univ Pisa Derivati 1,3-diaza-4-ossa-[3.3.1]-biciclici, loro preparazione e uso come medicinale, in particolare per il trattamento del diabete
CN112771055B (zh) 2018-08-08 2023-10-20 住友制药株式会社 光学活性桥接哌啶衍生物
BR112021002090A8 (pt) 2018-08-27 2022-12-06 Sumitomo Dainippon Pharma Co Ltd Derivado azabicíclico opticamente ativo

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002360732A1 (en) * 2001-12-26 2003-07-24 Guilford Pharmaceuticals Change inhibitors of dipeptidyl peptidase iv
TW200401635A (en) * 2002-07-23 2004-02-01 Yamanouchi Pharma Co Ltd 2-Cyano-4-fluoropyrrolidine derivative or salt thereof

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