JP2007507472A - ソマトスタチン受容体サブタイプ４（ｓｓｔｒ４）及び１（ｓｓｔｒ１）に作用するスルホニルアミノ−ペプチド模倣薬 - Google Patents

ソマトスタチン受容体サブタイプ４（ｓｓｔｒ４）及び１（ｓｓｔｒ１）に作用するスルホニルアミノ−ペプチド模倣薬 Download PDF

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JP2007507472A
JP2007507472A JP2006530316A JP2006530316A JP2007507472A JP 2007507472 A JP2007507472 A JP 2007507472A JP 2006530316 A JP2006530316 A JP 2006530316A JP 2006530316 A JP2006530316 A JP 2006530316A JP 2007507472 A JP2007507472 A JP 2007507472A
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compound
amino
mmol
resin
dmf
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JP2007507472A5 (cg-RX-API-DMAC7.html
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トンペリ，ユッシ
エングストロム，ミア
ブルスター，ジークフリート
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C07K5/06095—Arg-amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2006530316A 2003-10-06 2004-10-05 ソマトスタチン受容体サブタイプ４（ｓｓｔｒ４）及び１（ｓｓｔｒ１）に作用するスルホニルアミノ−ペプチド模倣薬 Pending JP2007507472A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50827003P 2003-10-06 2003-10-06
FI20031455A FI20031455A0 (fi) 2003-10-06 2003-10-06 Sulfonyyliamino-peptidomimeettejä, jotka ovat aktiivisia somatostatiinireseptorialatyyppien 4 (SSTR4) ja 1 (SSTR1) suhteen
PCT/FI2004/000583 WO2005033124A1 (en) 2003-10-06 2004-10-05 Sulfonylamino-peptidomimetics active on the somatostatin receptor subtypes 4 (sstr4) and 1 (sstr1)

Publications (2)

Publication Number Publication Date
JP2007507472A true JP2007507472A (ja) 2007-03-29
JP2007507472A5 JP2007507472A5 (cg-RX-API-DMAC7.html) 2007-11-22

Family

ID=29225904

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006530316A Pending JP2007507472A (ja) 2003-10-06 2004-10-05 ソマトスタチン受容体サブタイプ４（ｓｓｔｒ４）及び１（ｓｓｔｒ１）に作用するスルホニルアミノ−ペプチド模倣薬

Country Status (6)

Country Link
US (1) US20070129313A1 (cg-RX-API-DMAC7.html)
EP (1) EP1678196B1 (cg-RX-API-DMAC7.html)
JP (1) JP2007507472A (cg-RX-API-DMAC7.html)
AT (1) ATE404580T1 (cg-RX-API-DMAC7.html)
FI (1) FI20031455A0 (cg-RX-API-DMAC7.html)
WO (1) WO2005033124A1 (cg-RX-API-DMAC7.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007507473A (ja) * 2003-10-06 2007-03-29 オサケユイチア ユバンティア ファーマ リミティド ソマトスタチン受容体１及び／又は４選択的アゴニスト及びアンタゴニスト
JP2023520005A (ja) * 2020-03-31 2023-05-15 武田薬品工業株式会社 Ｓｓｔｒ４アゴニストとしてのｎ－ヘテロアリールアルキル－２－（ヘテロシクリル及びヘテロシクリルメチル）アセトアミド誘導体

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100004339A1 (en) * 2003-10-06 2010-01-07 Oy Juvantia Pharma Ltd. Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists
WO2005082845A1 (en) * 2004-02-27 2005-09-09 Oy Juvantia Pharma Ltd Novel therapies with somatostatin receptor agonists
WO2005082844A1 (en) * 2004-02-27 2005-09-09 Oy Juvantia Pharma Ltd Treatment of diseases by using a somatostatin receptor agonist
US20100048549A1 (en) * 2005-05-18 2010-02-25 Siegfried Wurster Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4
US11136312B2 (en) 2017-05-12 2021-10-05 Board of Trustees of the Southern Illinois University 3,4,5-trisubstituted-1,2,4-triazoles and 3,4,5-trisubstituted-3-thio-1,2,4-triazoles and uses thereof
US11912687B2 (en) 2017-05-12 2024-02-27 Board of Trustees of the Southern Illinois University 3,4,5-trisubstituted-1,2,4-triazoles and 3,4,5-trisubstituted-3-thio-1,2,4-triazoles and uses thereof
JP7099717B2 (ja) * 2019-09-30 2022-07-12 株式会社理研バイオ ソマトスタチン受容体
WO2025247982A1 (en) 2024-05-29 2025-12-04 Grünenthal GmbH Piperazines which act as sstr4 modulators

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002092566A1 (en) * 2001-05-15 2002-11-21 Taisho Pharmaceutical Co.,Ltd. Arginine derivatives
WO2003026575A2 (en) * 2001-09-24 2003-04-03 Synaptic Pharmaceutical Corporation Molecules specific for npff receptors and uses thereof
WO2003026657A1 (en) * 2001-09-24 2003-04-03 Synaptic Pharmaceutical Corporation Compounds for the treatment of pain
JP2004155695A (ja) * 2002-11-06 2004-06-03 Taisho Pharmaceut Co Ltd Ｍｃ４受容体に対するリガンド
JP2007507473A (ja) * 2003-10-06 2007-03-29 オサケユイチア ユバンティア ファーマ リミティド ソマトスタチン受容体１及び／又は４選択的アゴニスト及びアンタゴニスト

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002092566A1 (en) * 2001-05-15 2002-11-21 Taisho Pharmaceutical Co.,Ltd. Arginine derivatives
WO2003026575A2 (en) * 2001-09-24 2003-04-03 Synaptic Pharmaceutical Corporation Molecules specific for npff receptors and uses thereof
WO2003026657A1 (en) * 2001-09-24 2003-04-03 Synaptic Pharmaceutical Corporation Compounds for the treatment of pain
JP2004155695A (ja) * 2002-11-06 2004-06-03 Taisho Pharmaceut Co Ltd Ｍｃ４受容体に対するリガンド
JP2007507473A (ja) * 2003-10-06 2007-03-29 オサケユイチア ユバンティア ファーマ リミティド ソマトスタチン受容体１及び／又は４選択的アゴニスト及びアンタゴニスト

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007507473A (ja) * 2003-10-06 2007-03-29 オサケユイチア ユバンティア ファーマ リミティド ソマトスタチン受容体１及び／又は４選択的アゴニスト及びアンタゴニスト
JP2023520005A (ja) * 2020-03-31 2023-05-15 武田薬品工業株式会社 Ｓｓｔｒ４アゴニストとしてのｎ－ヘテロアリールアルキル－２－（ヘテロシクリル及びヘテロシクリルメチル）アセトアミド誘導体
JP7739327B2 (ja) 2020-03-31 2025-09-16 武田薬品工業株式会社 Ｓｓｔｒ４アゴニストとしてのｎ－ヘテロアリールアルキル－２－（ヘテロシクリル及びヘテロシクリルメチル）アセトアミド誘導体

Also Published As

Publication number Publication date
WO2005033124A1 (en) 2005-04-14
FI20031455A0 (fi) 2003-10-06
EP1678196B1 (en) 2008-08-13
US20070129313A1 (en) 2007-06-07
ATE404580T1 (de) 2008-08-15
EP1678196A1 (en) 2006-07-12

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