JP2007507222A - 化学療法に対する応答を予測するための遺伝子発現マーカー - Google Patents
化学療法に対する応答を予測するための遺伝子発現マーカー Download PDFInfo
- Publication number
- JP2007507222A JP2007507222A JP2006533426A JP2006533426A JP2007507222A JP 2007507222 A JP2007507222 A JP 2007507222A JP 2006533426 A JP2006533426 A JP 2006533426A JP 2006533426 A JP2006533426 A JP 2006533426A JP 2007507222 A JP2007507222 A JP 2007507222A
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- Prior art keywords
- expression
- cancer
- array
- chemotherapy
- genes
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47397003P | 2003-05-28 | 2003-05-28 | |
| PCT/US2004/016553 WO2004111603A2 (en) | 2003-05-28 | 2004-05-24 | Gene expression markers for predicting response to chemotherapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007507222A true JP2007507222A (ja) | 2007-03-29 |
| JP2007507222A5 JP2007507222A5 (enExample) | 2007-06-14 |
Family
ID=33551472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006533426A Pending JP2007507222A (ja) | 2003-05-28 | 2004-05-24 | 化学療法に対する応答を予測するための遺伝子発現マーカー |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20050064455A1 (enExample) |
| EP (1) | EP1631689A2 (enExample) |
| JP (1) | JP2007507222A (enExample) |
| AU (1) | AU2004248120B2 (enExample) |
| CA (1) | CA2527285A1 (enExample) |
| WO (1) | WO2004111603A2 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010539973A (ja) * | 2007-10-05 | 2010-12-24 | パシフィック エッジ バイオテクノロジー リミティド | 胃腸癌での増殖の徴候及び予後 |
| JP2012523828A (ja) * | 2009-04-17 | 2012-10-11 | ユニヴェルシテ リブル ドゥ ブリュッセル | ガンにおけるアントラサイクリン系薬剤の効率を予測するための方法およびツール |
| JP2016508710A (ja) * | 2012-12-03 | 2016-03-24 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | ネオアジュバントベバシズマブを用いた化学療法に対する予測結果の評価 |
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|---|---|---|---|---|
| EP2261368A1 (en) * | 2002-03-13 | 2010-12-15 | Genomic Health, Inc. | Gene expression profiling in biopsied tumor tissues |
| US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| WO2005039382A2 (en) | 2003-06-24 | 2005-05-06 | Genomic Health | Prediction of likelihood of cancer recurrence |
| CA2848463A1 (en) | 2004-04-09 | 2005-10-27 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| AU2006249235B2 (en) | 2004-05-14 | 2010-11-11 | Abraxis Bioscience, Llc | Sparc and methods of use thereof |
| US8420603B2 (en) * | 2004-05-14 | 2013-04-16 | Abraxis Bioscience, Llc | SPARC and methods of use thereof |
| CA3061785A1 (en) * | 2004-11-05 | 2006-05-18 | Genomic Health, Inc. | Predicting response to chemotherapy using gene expression markers |
| WO2006105642A1 (en) * | 2005-04-05 | 2006-10-12 | British Columbia Cancer Agency | Biomarkers for the detection of lung cancer and uses thereof |
| CA2604549A1 (en) | 2005-04-13 | 2006-10-19 | Oncotest Gmbh | Gene expression profiles being predictive for the response of tumors to pharmaceutically effective compounds |
| US20070026424A1 (en) * | 2005-04-15 | 2007-02-01 | Powell Charles A | Gene profiles correlating with histology and prognosis |
| ES2404066T3 (es) * | 2005-09-21 | 2013-05-23 | Epigenomics Ag | Marcadores para la predicción del resultado de un tratamiento con antraciclina |
| US7598052B2 (en) * | 2005-10-11 | 2009-10-06 | The Regents Of The University Of Michigan | Expression profile of thyroid cancer |
| WO2007085497A2 (en) * | 2006-01-30 | 2007-08-02 | Epigenomics Ag | Markers for the prediction of outcome of anthracycline treatment |
| US20070207467A1 (en) * | 2006-03-01 | 2007-09-06 | Ming Xu | Detection of lymph node metastasis from gastric carcinoma |
| EP1994412A2 (en) * | 2006-03-31 | 2008-11-26 | Brystol-Myers Squibb Company | Biomarkers and methods for determining sensitivity to microtubule-stabilizing agents |
| US20100021424A1 (en) * | 2006-06-02 | 2010-01-28 | Vincent Brichard | Method For Identifying Whether A Patient Will Be Responder or Not to Immunotherapy |
| US20070281305A1 (en) * | 2006-06-05 | 2007-12-06 | Sean Wuxiong Cao | Detection of lymph node metastasis from gastric carcinoma |
| ES2427924T3 (es) * | 2006-06-30 | 2013-11-04 | Merck Sharp & Dohme Corp. | Biomarcador IGFBP2 |
| JP2010500577A (ja) * | 2006-08-07 | 2010-01-07 | ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム | 癌の予後および予測シグナチャーのプロテオミクスパターン |
| WO2008058018A2 (en) | 2006-11-02 | 2008-05-15 | Mayo Foundation For Medical Education And Research | Predicting cancer outcome |
| WO2008098086A2 (en) * | 2007-02-06 | 2008-08-14 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | A gene expression profile that predicts ovarian cancer subject response to chemotherapy |
| WO2008115561A2 (en) * | 2007-03-21 | 2008-09-25 | Bristol-Myers Squibb Company | Biomarkers and methods for determining sensitivity to microtubule-stabilizing agents |
| EP2228457A1 (en) * | 2007-08-16 | 2010-09-15 | Genomic Health, Inc. | Gene expression markers of recurrence risk in cancer patients after chemotherapy |
| EP2065475A1 (en) * | 2007-11-30 | 2009-06-03 | Siemens Healthcare Diagnostics GmbH | Method for therapy prediction in tumors having irregularities in the expression of at least one VEGF ligand and/or at least one ErbB-receptor |
| EP2641978A1 (en) * | 2008-05-12 | 2013-09-25 | Genomic Health, Inc. | Tests to predict responsiveness of cancer patients to chemotherapy treatment options |
| EP2806054A1 (en) * | 2008-05-28 | 2014-11-26 | Genomedx Biosciences Inc. | Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer |
| PL2297359T4 (pl) | 2008-05-30 | 2014-07-31 | Univ North Carolina Chapel Hill | Profile ekspresji genów do przewidywania skutków raka piersi |
| US10407731B2 (en) | 2008-05-30 | 2019-09-10 | Mayo Foundation For Medical Education And Research | Biomarker panels for predicting prostate cancer outcomes |
| US20100029491A1 (en) * | 2008-07-11 | 2010-02-04 | Maike Schmidt | Methods and compositions for diagnostic use for tumor treatment |
| EP3216874A1 (en) | 2008-09-05 | 2017-09-13 | TOMA Biosciences, Inc. | Methods for stratifying and annotating cancer drug treatment options |
| US20120041274A1 (en) | 2010-01-07 | 2012-02-16 | Myriad Genetics, Incorporated | Cancer biomarkers |
| GB0908467D0 (en) * | 2009-05-15 | 2009-06-24 | Univ Gent | Use of the gtpase rab27b as biomarker to stratify patients with estrogen-receptor-positive breast cancer and to monitor their disease progression |
| ES2351327B1 (es) * | 2009-07-01 | 2011-11-28 | Para La Investigacion Biomedica Del Hospital Universitario La Paz Fundacion | Método de obtención de datos útiles para la predicción de respuesta clínica a un tratamiento de un paciente con cáncer. |
| ES2351328B1 (es) * | 2009-07-10 | 2011-11-28 | Para La Investigacion Biomedica Del Hospital Universitario La Paz Fundacion | Método de obtención de datos útiles para la predicción de respuesta patológica a un tratamiento de un paciente con cáncer. |
| GB0917457D0 (en) * | 2009-10-06 | 2009-11-18 | Glaxosmithkline Biolog Sa | Method |
| WO2011060537A1 (en) * | 2009-11-20 | 2011-05-26 | The Governors Of The University Of Alberta | Predictive markers for taxane responsiveness and methods of use thereof |
| CN101760557B (zh) * | 2010-03-04 | 2013-08-14 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 一种辅助诊断肝细胞癌的试剂盒 |
| EP3812469A1 (en) | 2010-07-07 | 2021-04-28 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| WO2012030840A2 (en) | 2010-08-30 | 2012-03-08 | Myriad Genetics, Inc. | Gene signatures for cancer diagnosis and prognosis |
| KR20130113447A (ko) | 2010-09-24 | 2013-10-15 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 고정된 프라이머들을 이용하여 표적 dna의 직접적인 캡쳐, 증폭 및 서열화 |
| US20130267443A1 (en) | 2010-11-19 | 2013-10-10 | The Regents Of The University Of Michigan | ncRNA AND USES THEREOF |
| WO2013049666A1 (en) | 2011-09-30 | 2013-04-04 | Sarcotein Diagnostics, Llc | Bin1 expression as a marker of cancer |
| EP2785873A4 (en) * | 2011-11-30 | 2015-11-11 | Univ North Carolina | METHOD FOR THE TREATMENT OF BREAST CANCER WITH TAXAN THERAPY |
| WO2013090620A1 (en) * | 2011-12-13 | 2013-06-20 | Genomedx Biosciences, Inc. | Cancer diagnostics using non-coding transcripts |
| KR20150023904A (ko) | 2012-06-27 | 2015-03-05 | 버그 엘엘씨 | 전립선암의 진단 및 치료에서의 마커의 용도 |
| SI2880447T1 (sl) * | 2012-07-31 | 2019-09-30 | Novartis Ag | Označevalci povezani z občutljivostjo na inhibitorje humanega dvominutnega 2 proteina (mdm2) |
| ES2945036T3 (es) | 2012-08-16 | 2023-06-28 | Veracyte Sd Inc | Pronóstico del cáncer de próstata mediante biomarcadores |
| WO2014078700A1 (en) | 2012-11-16 | 2014-05-22 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| US9535055B2 (en) | 2013-03-28 | 2017-01-03 | Samsung Electronics Co., Ltd. | Marker for determining effects of anti-c-Met antibody and method of determining effects of anti-c-Met antibody using the marker |
| CN110444289A (zh) * | 2013-06-28 | 2019-11-12 | 南托米克斯有限责任公司 | 用于诊断检测的识别的途径分析 |
| HK1215453A1 (zh) * | 2013-07-03 | 2016-08-26 | 豪夫迈.罗氏有限公司 | 用於将用mdm2拮抗剂进行患者癌症治疗个人化的基於mrna的基因表达 |
| US9657351B2 (en) | 2013-12-06 | 2017-05-23 | Hoffman-La Roche Inc. | MRNA-based gene expression for personalizing patient cancer therapy with an MDM2 antagonist |
| KR20150088433A (ko) | 2014-01-24 | 2015-08-03 | 삼성전자주식회사 | c-Met 저해제의 효능 예측을 위한 바이오마커 TFF1 |
| EP3143160B1 (en) | 2014-05-13 | 2019-11-06 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| SG11201704660YA (en) | 2014-12-08 | 2017-07-28 | Berg Llc | Use of markers including filamin a in the diagnosis and treatment of prostate cancer |
| JP6742330B2 (ja) | 2015-03-02 | 2020-08-19 | サーコーティン ダイアグノスティックス エルエルシー | 心臓障害のマーカーとしての13+/17+bin1発現 |
| WO2017075174A1 (en) * | 2015-10-29 | 2017-05-04 | The Research Foundation For The State University Of New York | Keratin 17 as a prognostic marker for pancreatic cancer |
| CN105986034A (zh) * | 2016-06-15 | 2016-10-05 | 南京卡迪睿伯生物技术有限公司 | 一组胃癌基因的应用 |
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| US4699877A (en) * | 1982-11-04 | 1987-10-13 | The Regents Of The University Of California | Methods and compositions for detecting human tumors |
| USRE35491E (en) * | 1982-11-04 | 1997-04-08 | The Regents Of The University Of California | Methods and compositions for detecting human tumors |
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-
2004
- 2004-05-24 EP EP04776118A patent/EP1631689A2/en not_active Withdrawn
- 2004-05-24 AU AU2004248120A patent/AU2004248120B2/en not_active Expired
- 2004-05-24 WO PCT/US2004/016553 patent/WO2004111603A2/en not_active Ceased
- 2004-05-24 JP JP2006533426A patent/JP2007507222A/ja active Pending
- 2004-05-24 CA CA002527285A patent/CA2527285A1/en not_active Abandoned
- 2004-05-24 US US10/852,797 patent/US20050064455A1/en not_active Abandoned
Non-Patent Citations (2)
| Title |
|---|
| JPN6010038077, 医学のあゆみ, (2002), 203, [3], p.189−190 * |
| JPN6010038078, Nat. Med., (2001), 7, [2], p.192−198 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010539973A (ja) * | 2007-10-05 | 2010-12-24 | パシフィック エッジ バイオテクノロジー リミティド | 胃腸癌での増殖の徴候及び予後 |
| JP2015165811A (ja) * | 2007-10-05 | 2015-09-24 | パシフィック エッジ バイオテクノロジー リミティド | 胃腸癌での増殖の徴候及び予後 |
| JP2017060517A (ja) * | 2007-10-05 | 2017-03-30 | パシフィック エッジ バイオテクノロジー リミティド | 胃腸癌での増殖の徴候及び予後 |
| JP2018126154A (ja) * | 2007-10-05 | 2018-08-16 | パシフィック エッジ リミテッド | 胃腸癌での増殖の徴候及び予後 |
| JP2012523828A (ja) * | 2009-04-17 | 2012-10-11 | ユニヴェルシテ リブル ドゥ ブリュッセル | ガンにおけるアントラサイクリン系薬剤の効率を予測するための方法およびツール |
| JP2016508710A (ja) * | 2012-12-03 | 2016-03-24 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | ネオアジュバントベバシズマブを用いた化学療法に対する予測結果の評価 |
| US10460831B2 (en) | 2012-12-03 | 2019-10-29 | Koninklijke Philips N.V. | Predictive outcome assessment for chemotherapy with neoadjuvant bevacizumab |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004111603A3 (en) | 2005-07-21 |
| WO2004111603A2 (en) | 2004-12-23 |
| EP1631689A2 (en) | 2006-03-08 |
| AU2004248120B2 (en) | 2009-04-23 |
| CA2527285A1 (en) | 2004-12-23 |
| AU2004248120A1 (en) | 2004-12-23 |
| US20050064455A1 (en) | 2005-03-24 |
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