JP2007506838A - 反応性を有する親水性オリゴマー - Google Patents
反応性を有する親水性オリゴマー Download PDFInfo
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- JP2007506838A JP2007506838A JP2006528010A JP2006528010A JP2007506838A JP 2007506838 A JP2007506838 A JP 2007506838A JP 2006528010 A JP2006528010 A JP 2006528010A JP 2006528010 A JP2006528010 A JP 2006528010A JP 2007506838 A JP2007506838 A JP 2007506838A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F265/00—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00
- C08F265/04—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00 on to polymers of esters
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
- C08F283/06—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polyethers, polyoxymethylenes or polyacetals
-
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- C08F293/00—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
- C08F293/005—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule using free radical "living" or "controlled" polymerisation, e.g. using a complexing agent
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- C08L51/00—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
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- C09D151/00—Coating compositions based on graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers
- C09D151/003—Coating compositions based on graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers grafted on to macromolecular compounds obtained by reactions only involving unsaturated carbon-to-carbon bonds
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- C09D151/00—Coating compositions based on graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers
- C09D151/006—Coating compositions based on graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers grafted on to block copolymers containing at least one sequence of polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
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- C09D151/00—Coating compositions based on graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers
- C09D151/08—Coating compositions based on graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers grafted on to macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/672,580 US20050070688A1 (en) | 2003-09-26 | 2003-09-26 | Reactive hydrophilic oligomers |
| PCT/US2004/027879 WO2005035607A1 (en) | 2003-09-26 | 2004-08-27 | Reactive hydrophilic oligomers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007506838A true JP2007506838A (ja) | 2007-03-22 |
| JP2007506838A5 JP2007506838A5 (enExample) | 2007-10-11 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| JP2006528010A Pending JP2007506838A (ja) | 2003-09-26 | 2004-08-27 | 反応性を有する親水性オリゴマー |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US20050070688A1 (enExample) |
| EP (1) | EP1668052B1 (enExample) |
| JP (1) | JP2007506838A (enExample) |
| AT (1) | ATE358687T1 (enExample) |
| DE (1) | DE602004005727T2 (enExample) |
| WO (1) | WO2005035607A1 (enExample) |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0588365A (ja) * | 1991-02-21 | 1993-04-09 | Minnesota Mining & Mfg Co <3M> | 高速で水性溶媒によつて現像できる感光性重合体組成物 |
| JPH08509019A (ja) * | 1993-04-14 | 1996-09-24 | ミネソタ マイニング アンド マニュファクチャリング カンパニー | 架橋吸収性感圧接着剤及び外傷包帯 |
| JPH09194548A (ja) * | 1996-01-11 | 1997-07-29 | Nippon Kayaku Co Ltd | 樹脂組成物及びその硬化物 |
| JP2000248023A (ja) * | 1999-03-01 | 2000-09-12 | Kyoeisha Chem Co Ltd | インク受像層用硬化性組成物 |
| JP2004508435A (ja) * | 2000-09-08 | 2004-03-18 | スリーエム イノベイティブ プロパティズ カンパニー | 架橋性高分子組成物およびその使用 |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US738498A (en) * | 1903-04-13 | 1903-09-08 | Julius Solberg | Detachable connection for chains. |
| USRE24906E (en) * | 1955-11-18 | 1960-12-13 | Pressure-sensitive adhesive sheet material | |
| US3121021A (en) * | 1960-04-18 | 1964-02-11 | Minnesota Mining & Mfg | Breathable surgical adhesive tapes |
| US4112213A (en) * | 1964-09-28 | 1978-09-05 | Johnson & Johnson | Pressure sensitive adhesive tapes and method of making same |
| US3389827A (en) * | 1967-04-10 | 1968-06-25 | Minnesota Mining & Mfg | Easy-open container and sealing tape |
| BR7606383A (pt) * | 1975-09-26 | 1977-06-14 | Bayer Ag | Processo para a preparacao de poliuretanos |
| DE2555534C3 (de) * | 1975-12-10 | 1981-01-08 | Bayer Ag, 5090 Leverkusen | In Wasser dispergierbare Polyurethane |
| US4385164A (en) * | 1976-03-10 | 1983-05-24 | The Goodyear Tire & Rubber Company | Block copolymer dispersion stabilizer and aqueous dispersion polymerization therewith |
| DE2642073C2 (de) * | 1976-09-18 | 1984-08-16 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung eines vernetzten Flächengebildes |
| US4499896A (en) * | 1982-03-30 | 1985-02-19 | Minnesota Mining And Manufacturing Co. | Reservoir wound dressing |
| US4598004A (en) * | 1985-01-24 | 1986-07-01 | Minnesota Mining And Manufacturing Company | Thin film surgical dressing with delivery system |
| US4694054A (en) * | 1985-03-01 | 1987-09-15 | E. I. Du Pont De Nemours And Company | Cobalt(II) chelates as chain transfer agents in free radical polymerizations |
| US4680352A (en) * | 1985-03-01 | 1987-07-14 | E. I. Du Pont De Nemours And Company | Cobalt (II) chelates as chain transfer agents in free radical polymerizations |
| US4849458A (en) * | 1988-06-17 | 1989-07-18 | Matrix Medica, Inc. | Segmented polyether polyurethane |
| US5264530A (en) * | 1992-05-01 | 1993-11-23 | E. I. Du Pont De Nemours And Company | Process of polymerization in an aqueous system |
| US5773534A (en) * | 1992-05-22 | 1998-06-30 | E. I. Du Pont De Nemours And Company | Preparing crosslinkable polymers employing macromonomer chain transfer agents |
| DK0690706T3 (da) * | 1993-03-22 | 2001-01-08 | Minnesota Mining & Mfg | Bandage, der leveres med en ramme uden vindue, samt fremgangsmåde til fremstilling heraf |
| US5506279A (en) * | 1993-10-13 | 1996-04-09 | Minnesota Mining And Manufacturing Company | Acrylamido functional disubstituted acetyl aryl ketone photoinitiators |
| JP3548933B2 (ja) * | 1994-07-29 | 2004-08-04 | ミネソタ マイニング アンド マニュファクチャリング カンパニー | 架橋結合された粘弾性高分子材料に硬化可能なアクリル系シロップ |
| US5653699A (en) * | 1994-09-13 | 1997-08-05 | Polymedica Industries, Inc. | Spyrosorbent wound dressings for exudate management |
| US5614310A (en) * | 1994-11-04 | 1997-03-25 | Minnesota Mining And Manufacturing Company | Low trauma wound dressing with improved moisture vapor permeability |
| ES2133944T3 (es) * | 1995-02-10 | 1999-09-16 | Minnesota Mining & Mfg | Adhesivo de contacto reticulable y proceso para la produccion de un articulo recubierto con un adhesivo de contacto reticulado. |
| US6254555B1 (en) * | 1996-08-12 | 2001-07-03 | Primary Care Delivery Corporation | Instrument for diagnosing and treating soft tissue abnormalities through augmented soft tissue mobilization |
| US5733570A (en) * | 1996-09-05 | 1998-03-31 | Minnesota Mining And Manufacturing Company | Absorbent dressing |
| US5849325A (en) * | 1996-10-07 | 1998-12-15 | Minnesota Mining And Manufacturing Company | Moisture-regulating adhesive dressing |
| ES2175698T3 (es) * | 1997-02-21 | 2002-11-16 | Novartis Ag | Articulos de moldeo oftalmicos. |
| US6420622B1 (en) | 1997-08-01 | 2002-07-16 | 3M Innovative Properties Company | Medical article having fluid control film |
| FR2768341B1 (fr) | 1997-09-18 | 2000-04-14 | Lab Francais Du Fractionnement | Composition pharmaceutique placebo lyophilisable destinee a imiter un medicament, notamment a base de proteines ou de polypeptides |
| ES2373861T3 (es) | 1997-09-18 | 2012-02-09 | Pacira Pharmaceuticals, Inc. | Composiciones anestésicas liposomiales de liberación sostenida. |
| US6171985B1 (en) * | 1997-12-01 | 2001-01-09 | 3M Innovative Properties Company | Low trauma adhesive article |
| US6007833A (en) * | 1998-03-19 | 1999-12-28 | Surmodics, Inc. | Crosslinkable macromers bearing initiator groups |
| US6198016B1 (en) * | 1998-12-01 | 2001-03-06 | 3M Innovative Properties Company | Wet skin adhesive article |
| US6361768B1 (en) * | 1998-12-29 | 2002-03-26 | Pmd Holdings Corp. | Hydrophilic ampholytic polymer |
| AU766397B2 (en) * | 1999-09-07 | 2003-10-16 | Alcon Inc. | Ophthalmic and otorhinolaryngological device materials |
| US6566575B1 (en) | 2000-02-15 | 2003-05-20 | 3M Innovative Properties Company | Patterned absorbent article for wound dressing |
| ATE318566T1 (de) * | 2000-03-10 | 2006-03-15 | 3M Innovative Properties Co | Medizinischer wundverband mit mehreren klebern und herstellungsverfahren |
| US6559223B2 (en) * | 2001-02-22 | 2003-05-06 | Polytechnic University | Hydrogels and methods for their production |
| US6635690B2 (en) * | 2001-06-19 | 2003-10-21 | 3M Innovative Properties Company | Reactive oligomers |
| US7005143B2 (en) | 2002-04-12 | 2006-02-28 | 3M Innovative Properties Company | Gel materials, medical articles, and methods |
| US7148265B2 (en) * | 2002-09-30 | 2006-12-12 | Rohm And Haas Electronic Materials Llc | Functional polymer |
| US20050070688A1 (en) | 2003-09-26 | 2005-03-31 | 3M Innovative Properties Company | Reactive hydrophilic oligomers |
| US7384984B2 (en) | 2003-12-10 | 2008-06-10 | 3M Innovative Properties Company | Reactive hydrophilic oligomers |
| US7074839B2 (en) | 2004-03-01 | 2006-07-11 | 3M Innovative Properties Company | Crosslinkable hydrophilic materials from reactive oligomers having pendent photoinitiator groups |
| US7342047B2 (en) | 2004-03-02 | 2008-03-11 | 3M Innovative Properties Company | Crosslinkable hydrophilic materials from reactive oligomers having pendent unsaturated groups |
| US8609131B2 (en) | 2005-01-25 | 2013-12-17 | 3M Innovative Properties Company | Absorbent dressing comprising hydrophilic polymer prepared via Michael reaction |
-
2003
- 2003-09-26 US US10/672,580 patent/US20050070688A1/en not_active Abandoned
-
2004
- 2004-08-27 WO PCT/US2004/027879 patent/WO2005035607A1/en not_active Ceased
- 2004-08-27 AT AT04782375T patent/ATE358687T1/de not_active IP Right Cessation
- 2004-08-27 DE DE602004005727T patent/DE602004005727T2/de not_active Expired - Lifetime
- 2004-08-27 JP JP2006528010A patent/JP2007506838A/ja active Pending
- 2004-08-27 EP EP04782375A patent/EP1668052B1/en not_active Expired - Lifetime
-
2006
- 2006-08-08 US US11/463,103 patent/US7459489B2/en not_active Expired - Fee Related
-
2008
- 2008-11-04 US US12/264,516 patent/US7598298B2/en not_active Expired - Fee Related
-
2009
- 2009-09-08 US US12/555,354 patent/US7659323B2/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0588365A (ja) * | 1991-02-21 | 1993-04-09 | Minnesota Mining & Mfg Co <3M> | 高速で水性溶媒によつて現像できる感光性重合体組成物 |
| JPH08509019A (ja) * | 1993-04-14 | 1996-09-24 | ミネソタ マイニング アンド マニュファクチャリング カンパニー | 架橋吸収性感圧接着剤及び外傷包帯 |
| JPH09194548A (ja) * | 1996-01-11 | 1997-07-29 | Nippon Kayaku Co Ltd | 樹脂組成物及びその硬化物 |
| JP2000248023A (ja) * | 1999-03-01 | 2000-09-12 | Kyoeisha Chem Co Ltd | インク受像層用硬化性組成物 |
| JP2004508435A (ja) * | 2000-09-08 | 2004-03-18 | スリーエム イノベイティブ プロパティズ カンパニー | 架橋性高分子組成物およびその使用 |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008506800A (ja) * | 2004-07-16 | 2008-03-06 | コラノ・アクチェンゲゼルシャフト | ヒドロコロイドを含むホットメルト組成物 |
| JP2008189706A (ja) * | 2007-02-01 | 2008-08-21 | Showa Highpolymer Co Ltd | 活性エネルギー線自己硬化型水性樹脂組成物 |
| JP2013532215A (ja) * | 2010-06-22 | 2013-08-15 | コロプラスト アクティーゼルスカブ | ポリアルキルエーテル系光開始剤由来の肌にやさしい接着剤 |
| JP2016118797A (ja) * | 2010-07-30 | 2016-06-30 | ノバルティス アーゲー | 架橋親水性コーティングを備えるシリコーンヒドロゲルレンズ |
| JP2016122203A (ja) * | 2010-07-30 | 2016-07-07 | ノバルティス アーゲー | 架橋親水性コーティングを備えるシリコーンヒドロゲルレンズ |
| JP2016519171A (ja) * | 2013-03-14 | 2016-06-30 | スリーエム イノベイティブ プロパティズ カンパニー | 上昇されたｗｖｔｒを有するヒドロコロイド創傷包帯 |
| JP2018504167A (ja) * | 2014-12-09 | 2018-02-15 | タンジブル サイエンス， リミテッド ライアビリティ カンパニー | 生体適合性層を有する医療デバイスコーティング |
| WO2016204258A1 (ja) * | 2015-06-19 | 2016-12-22 | 日産化学工業株式会社 | ゲル形成用ポリマー及び皮膚用粘着性材料 |
Also Published As
| Publication number | Publication date |
|---|---|
| ATE358687T1 (de) | 2007-04-15 |
| EP1668052A1 (en) | 2006-06-14 |
| US20090326498A1 (en) | 2009-12-31 |
| US20060292209A1 (en) | 2006-12-28 |
| US20050070688A1 (en) | 2005-03-31 |
| US7659323B2 (en) | 2010-02-09 |
| WO2005035607A1 (en) | 2005-04-21 |
| US20090062711A1 (en) | 2009-03-05 |
| US7598298B2 (en) | 2009-10-06 |
| EP1668052B1 (en) | 2007-04-04 |
| DE602004005727T2 (de) | 2007-12-27 |
| US7459489B2 (en) | 2008-12-02 |
| DE602004005727D1 (de) | 2007-05-16 |
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