JP2007506801A5 - - Google Patents

Info

Publication number

JP2007506801A5

JP2007506801A5 JP2006533141A JP2006533141A JP2007506801A5 JP 2007506801 A5 JP2007506801 A5 JP 2007506801A5 JP 2006533141 A JP2006533141 A JP 2006533141A JP 2006533141 A JP2006533141 A JP 2006533141A JP 2007506801 A5 JP2007506801 A5 JP 2007506801A5

Authority

JP

Japan

Prior art keywords

modafinil

composition

use according

agent

cisplatinum

Prior art date

2004-05-17

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Withdrawn

Links

• Espacenet
• Global Dossier
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• YFGHCGITMMYXAQ-UHFFFAOYSA-N 2-[(diphenylmethyl)sulfinyl]acetamide Chemical compound C=1C=CC=CC=1C(S(=O)CC(=O)N)C1=CC=CC=C1 YFGHCGITMMYXAQ-UHFFFAOYSA-N 0.000 claims 17
• 229960001165 modafinil Drugs 0.000 claims 17
• 239000002246 antineoplastic agent Substances 0.000 claims 9
• 239000000203 mixture Substances 0.000 claims 7
• ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 claims 3
• 229930012538 Paclitaxel Natural products 0.000 claims 3
• 229940034982 antineoplastic agent Drugs 0.000 claims 3
• -1 cisplatinum Chemical compound 0.000 claims 3
• 229960003668 docetaxel Drugs 0.000 claims 3
• 229960001592 paclitaxel Drugs 0.000 claims 3
• RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 3
• OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 claims 3
• 229960004528 vincristine Drugs 0.000 claims 3
• OGWKCGZFUXNPDA-UHFFFAOYSA-N vincristine Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(OC(C)=O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-UHFFFAOYSA-N 0.000 claims 3
• 230000002411 adverse Effects 0.000 claims 2
• 239000003814 drug Substances 0.000 claims 2
• 238000004519 manufacturing process Methods 0.000 claims 2
• 230000000118 anti-neoplastic effect Effects 0.000 claims 1
• 229940041181 antineoplastic drug Drugs 0.000 claims 1
• 238000002651 drug therapy Methods 0.000 claims 1
• 239000008194 pharmaceutical composition Substances 0.000 claims 1