JP2005511597A5 - - Google Patents

Info

Publication number

JP2005511597A5

JP2005511597A5 JP2003541842A JP2003541842A JP2005511597A5 JP 2005511597 A5 JP2005511597 A5 JP 2005511597A5 JP 2003541842 A JP2003541842 A JP 2003541842A JP 2003541842 A JP2003541842 A JP 2003541842A JP 2005511597 A5 JP2005511597 A5 JP 2005511597A5

Authority

JP

Japan

Prior art keywords

taxane

effect

pharmaceutically acceptable

acceptable salt

medicament

Prior art date

2002-11-06

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 229940123237 Taxane Drugs 0.000 claims 8
• DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 claims 8
• 150000003839 salts Chemical class 0.000 claims 6
• 241001465754 Metazoa Species 0.000 claims 4
• 230000001093 anti-cancer Effects 0.000 claims 4
• 239000003814 drug Substances 0.000 claims 4
• 238000004519 manufacturing process Methods 0.000 claims 4
• 230000001772 anti-angiogenic effect Effects 0.000 claims 2
• 230000000259 anti-tumor effect Effects 0.000 claims 2
• 230000000694 effects Effects 0.000 claims 2
• 230000005865 ionizing radiation Effects 0.000 claims 2
• 230000008728 vascular permeability Effects 0.000 claims 2
• 241000282412 Homo Species 0.000 claims 1
• 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
• ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 claims 1
• 206010028980 Neoplasm Diseases 0.000 claims 1
• 229930012538 Paclitaxel Natural products 0.000 claims 1
• 201000011510 cancer Diseases 0.000 claims 1
• 229960003668 docetaxel Drugs 0.000 claims 1
• 239000003937 drug carrier Substances 0.000 claims 1
• 201000005202 lung cancer Diseases 0.000 claims 1
• 208000020816 lung neoplasm Diseases 0.000 claims 1
• 229960001592 paclitaxel Drugs 0.000 claims 1
• 239000008194 pharmaceutical composition Substances 0.000 claims 1
• 239000000546 pharmaceutical excipient Substances 0.000 claims 1
• RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 1