DK1446124T3 - Kombinationsterapi, der omfatter ZD6474 og et taxan - Google Patents

Kombinationsterapi, der omfatter ZD6474 og et taxan

Info

Publication number
DK1446124T3
DK1446124T3 DK02772624T DK02772624T DK1446124T3 DK 1446124 T3 DK1446124 T3 DK 1446124T3 DK 02772624 T DK02772624 T DK 02772624T DK 02772624 T DK02772624 T DK 02772624T DK 1446124 T3 DK1446124 T3 DK 1446124T3
Authority
DK
Denmark
Prior art keywords
taxane
combination therapy
therapy
combination
Prior art date
Application number
DK02772624T
Other languages
English (en)
Inventor
Stephen Robert Wedge
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK1446124T3 publication Critical patent/DK1446124T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK02772624T 2001-11-08 2002-11-06 Kombinationsterapi, der omfatter ZD6474 og et taxan DK1446124T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0126879.6A GB0126879D0 (en) 2001-11-08 2001-11-08 Combination therapy

Publications (1)

Publication Number Publication Date
DK1446124T3 true DK1446124T3 (da) 2006-11-13

Family

ID=9925430

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02772624T DK1446124T3 (da) 2001-11-08 2002-11-06 Kombinationsterapi, der omfatter ZD6474 og et taxan

Country Status (23)

Country Link
US (2) US20050043395A1 (da)
EP (1) EP1446124B1 (da)
JP (1) JP4694127B2 (da)
KR (1) KR100959607B1 (da)
CN (1) CN1298328C (da)
AR (1) AR037346A1 (da)
AT (1) ATE335488T1 (da)
AU (1) AU2002337382B2 (da)
BR (1) BR0213906A (da)
CA (1) CA2464758C (da)
CY (1) CY1106259T1 (da)
DE (1) DE60213845T2 (da)
DK (1) DK1446124T3 (da)
ES (1) ES2269769T3 (da)
GB (1) GB0126879D0 (da)
HK (1) HK1068546A1 (da)
IL (2) IL161744A0 (da)
MX (1) MXPA04004355A (da)
NO (1) NO328048B1 (da)
NZ (1) NZ532525A (da)
PT (1) PT1446124E (da)
WO (1) WO2003039551A1 (da)
ZA (1) ZA200403455B (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100376567C (zh) 1999-11-05 2008-03-26 阿斯特拉曾尼卡有限公司 作为vegf抑制剂的喹唑啉衍生物
GB0008269D0 (en) 2000-04-05 2000-05-24 Astrazeneca Ab Combination chemotherapy
DE60121931T2 (de) * 2000-04-07 2007-03-01 Astrazeneca Ab Chinazolinverbindungen
KR101093345B1 (ko) 2002-02-01 2011-12-14 아스트라제네카 아베 퀴나졸린 화합물
TW200813014A (en) * 2002-03-28 2008-03-16 Astrazeneca Ab Quinazoline derivatives
GB0218526D0 (en) * 2002-08-09 2002-09-18 Astrazeneca Ab Combination therapy
GB0223380D0 (en) * 2002-10-09 2002-11-13 Astrazeneca Ab Combination therapy
RU2350618C2 (ru) 2002-11-04 2009-03-27 Астразенека Аб ПРОИЗВОДНЫЕ ХИНАЗОЛИНА В КАЧЕСТВЕ ИНГИБИТОРОВ Src ТИРОЗИНКИНАЗЫ
DK1592423T3 (da) * 2003-02-13 2011-06-27 Astrazeneca Ab Kombinationsterapi af ZD6474 med 5-FU og/eller CPT-11
GB0310401D0 (en) * 2003-05-07 2003-06-11 Astrazeneca Ab Therapeutic agent
NZ544458A (en) * 2003-07-10 2009-04-30 Astrazeneca Ab Use of the quinazoline derivative ZD6474 combined with platinum compounds and optionally ionising radiation in the treatment of diseases associated with angiogenesis and/or increased vascular permeability
US20080255132A1 (en) * 2003-11-14 2008-10-16 Eric Rowinsky Combination Therapy Comprising the Use of Et-743 and Paclitaxel for Treating Cancer
GB0406445D0 (en) * 2004-03-23 2004-04-28 Astrazeneca Ab Combination therapy
EP1765313A2 (en) * 2004-06-24 2007-03-28 Novartis Vaccines and Diagnostics, Inc. Compounds for immunopotentiation
BRPI0516052A (pt) * 2004-09-27 2008-08-19 Astrazeneca Ab uso de zd6474 ou de um sal farmaceuticamente aceitável do mesmo e de imatinib, composição farmacêutica, kit, e, método para a produção de um efeito antiangiogênico e/ou de redução da permeabilidade vascular em um animal de sangue quente
GB0424339D0 (en) * 2004-11-03 2004-12-08 Astrazeneca Ab Combination therapy
GB0519879D0 (en) 2005-09-30 2005-11-09 Astrazeneca Ab Chemical process
DK1971338T3 (da) * 2005-12-22 2011-05-23 Astrazeneca Ab Kombination af ZD6474 og pemetrexed
WO2007139930A2 (en) * 2006-05-26 2007-12-06 Bayer Healthcare Llc Drug combinations with substituted diaryl ureas for the treatment of cancer
JP2010504949A (ja) * 2006-09-29 2010-02-18 アストラゼネカ アクチボラグ Zd6474とベバシズマブの癌療法のための組合せ
US20080190689A1 (en) * 2007-02-12 2008-08-14 Ballard Ebbin C Inserts for engine exhaust systems
CA2723989C (en) * 2008-05-13 2017-04-25 Astrazeneca Ab Fumarate salt of 4-(3-chloro-2-fluoroanilino)-7-methoxy-6-{[1-(n-methylcarbamoylmethyl)piperidin-4-yl]oxy}quinazoline
WO2010061208A2 (en) * 2008-11-03 2010-06-03 Astrazeneca Ab Therapeutic treatment 555
CN106478598B (zh) * 2016-08-30 2018-11-13 山东罗欣药业集团股份有限公司 一种凡德他尼水合物晶体及其制备方法
CN106397401B (zh) * 2016-08-30 2018-11-13 山东罗欣药业集团股份有限公司 一种抗癌药物的晶体化合物及其制备方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565478A (en) * 1994-03-14 1996-10-15 The United States Of America As Represented By The Department Of Health & Human Services Combination therapy using signal transduction inhibitors with paclitaxel and other taxane analogs
WO1997040835A1 (en) * 1996-04-26 1997-11-06 Magainin Pharmaceuticals Inc. Treatment of carcinomas using squalamine in combination with other anti-cancer agents
GB9718972D0 (en) * 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
GB9727524D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Synergistic antitumor composition containing a biologically active ureido compound
AU768027B2 (en) * 1999-02-24 2003-11-27 Uab Research Foundation, The Taxane derivatives for targeted therapy of cancer
JP4926320B2 (ja) * 1999-04-28 2012-05-09 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム Vegfの選択的阻害による癌処置のための組成物および方法
CN100376567C (zh) * 1999-11-05 2008-03-26 阿斯特拉曾尼卡有限公司 作为vegf抑制剂的喹唑啉衍生物
TWI310684B (en) * 2000-03-27 2009-06-11 Bristol Myers Squibb Co Synergistic pharmaceutical kits for treating cancer
GB0008269D0 (en) * 2000-04-05 2000-05-24 Astrazeneca Ab Combination chemotherapy
GB0218526D0 (en) * 2002-08-09 2002-09-18 Astrazeneca Ab Combination therapy
BR0313116A (pt) * 2002-08-09 2005-07-05 Astrazeneca Ab Método para a produção de um efeito redutor de permeabilidade vascular e/ou antiangiogênico em um animal de sangue quente tal como um humano, método para o tratamento de um câncer em um animal de sangue quente tal como humano, e, uso de zd6474 ou de um seu sal farmaceuticamente aceitável.
GB0223380D0 (en) * 2002-10-09 2002-11-13 Astrazeneca Ab Combination therapy
DK1592423T3 (da) * 2003-02-13 2011-06-27 Astrazeneca Ab Kombinationsterapi af ZD6474 med 5-FU og/eller CPT-11
NZ544458A (en) * 2003-07-10 2009-04-30 Astrazeneca Ab Use of the quinazoline derivative ZD6474 combined with platinum compounds and optionally ionising radiation in the treatment of diseases associated with angiogenesis and/or increased vascular permeability
BRPI0516052A (pt) * 2004-09-27 2008-08-19 Astrazeneca Ab uso de zd6474 ou de um sal farmaceuticamente aceitável do mesmo e de imatinib, composição farmacêutica, kit, e, método para a produção de um efeito antiangiogênico e/ou de redução da permeabilidade vascular em um animal de sangue quente
GB0424339D0 (en) * 2004-11-03 2004-12-08 Astrazeneca Ab Combination therapy
DK1971338T3 (da) * 2005-12-22 2011-05-23 Astrazeneca Ab Kombination af ZD6474 og pemetrexed
JP2010504949A (ja) * 2006-09-29 2010-02-18 アストラゼネカ アクチボラグ Zd6474とベバシズマブの癌療法のための組合せ

Also Published As

Publication number Publication date
NZ532525A (en) 2006-11-30
DE60213845T2 (de) 2007-03-29
KR100959607B1 (ko) 2010-05-27
BR0213906A (pt) 2004-08-31
EP1446124B1 (en) 2006-08-09
US20050043395A1 (en) 2005-02-24
ZA200403455B (en) 2005-08-29
WO2003039551A1 (en) 2003-05-15
JP2005511597A (ja) 2005-04-28
JP4694127B2 (ja) 2011-06-08
AU2002337382B2 (en) 2008-06-12
IL161744A (en) 2012-01-31
MXPA04004355A (es) 2004-08-11
GB0126879D0 (en) 2002-01-02
CN1298328C (zh) 2007-02-07
PT1446124E (pt) 2006-12-29
ES2269769T3 (es) 2007-04-01
KR20050043779A (ko) 2005-05-11
ATE335488T1 (de) 2006-09-15
NO20042365L (no) 2004-06-07
DE60213845D1 (de) 2006-09-21
CY1106259T1 (el) 2011-06-08
NO328048B1 (no) 2009-11-16
IL161744A0 (en) 2005-11-20
AR037346A1 (es) 2004-11-03
CA2464758A1 (en) 2003-05-15
EP1446124A1 (en) 2004-08-18
US20120252827A1 (en) 2012-10-04
HK1068546A1 (en) 2005-04-29
CA2464758C (en) 2010-09-28
CN1612738A (zh) 2005-05-04

Similar Documents

Publication Publication Date Title
DK1446124T3 (da) Kombinationsterapi, der omfatter ZD6474 og et taxan
DK1455785T3 (da) Substituerede 2-thio-3,5-dicyano-4-phenyl-6-aminopyridiner og deres anvendelse
NO20055568D0 (no) Substituerte 1,4-diazepiner og anvendelser derav
DE60317797D1 (de) Strahlungshärtbare prepolymere
NO20044662L (no) Forbindelser, blandinger og fremgangsmater
FR2823558B1 (fr) Glaciere portable
GB0203933D0 (en) Portable dummy sterilizer
DK1439839T3 (da) En forbindelse, der omfatter combretastatin og anticancermidler
DE60226693D1 (de) Härtbare Mischungen
NO20043279L (no) Kombinasjoner som innbefatter epotiloner og antimetabolitter
DE60333039D1 (de) Gasaufkohlungsverfahren
AU148766S (en) Portable drill
DE50214325D1 (de) Einblatt-Überkopf-Tor
ITTN20020014A1 (it) Apparecchio ortodontico.
DE50206805D1 (de) Schleuderradanordnung
ATA7562001A (de) Tor
ITRM20020308A1 (it) Apparecchiatura per trattamenti terapeutici, e relativo metodo.
NO20025770L (no) Nedbrytbar övelsesmine
ES1049537Y (es) Parquimetro portatil.
GB2380689B (en) Portable step
SI1446124T1 (sl) Kombinacijska terapija, ki obsega ZD6474 in taksan
HK1045060A2 (en) Supported wooden dummy
ITVI20010003U1 (it) Trampolo
PL112305U1 (en) Portable game
BR8100876Y1 (pt) consultàrio odontolàgico portÁtil.