JP2007500697A - 微生物病原体の毒性を減弱させる方法、および微生物のバイオフィルム形成を阻害する方法 - Google Patents
微生物病原体の毒性を減弱させる方法、および微生物のバイオフィルム形成を阻害する方法 Download PDFInfo
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- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000000304 virulence factor Substances 0.000 description 1
- 230000007923 virulence factor Effects 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US49002903P | 2003-07-28 | 2003-07-28 | |
| PCT/US2004/023498 WO2005030186A2 (en) | 2003-07-28 | 2004-07-22 | Method for attenuating virulence of microbial pathogens and for inhibiting microbial biofilm formation |
Publications (2)
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| JP2007500697A true JP2007500697A (ja) | 2007-01-18 |
| JP2007500697A5 JP2007500697A5 (https=) | 2007-09-13 |
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| US (1) | US8367716B2 (https=) |
| EP (1) | EP1651242A2 (https=) |
| JP (1) | JP2007500697A (https=) |
| AU (1) | AU2004275696B2 (https=) |
| CA (1) | CA2533873A1 (https=) |
| IL (1) | IL173065A (https=) |
| WO (1) | WO2005030186A2 (https=) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2014109256A1 (ja) * | 2013-01-09 | 2014-07-17 | 国立大学法人東北大学 | トリアゾール連結型環状ジヌクレオチド類縁体 |
| JP2016531842A (ja) * | 2013-05-18 | 2016-10-13 | アデュロ バイオテック，インコーポレイテッド | 「インターフェロン遺伝子の刺激因子」依存性シグナル伝達を抑制するための組成物および方法 |
| US10189873B2 (en) | 2013-05-18 | 2019-01-29 | Aduro Biotech, Inc. | Compositions and methods for inhibiting “stimulator of interferon gene”-dependent signalling |
| KR20200058411A (ko) * | 2017-08-30 | 2020-05-27 | 베이징 슈안이 파마사이언시스 컴퍼니, 리미티드 | 인터페론 유전자 조절인자의 자극제로서의 환식 다이-뉴클레오타이드 |
| KR102551061B1 (ko) * | 2022-05-26 | 2023-07-03 | 중앙대학교 산학협력단 | Saha를 유효성분으로 포함하는 살모넬라 속 균주에 의한 바이오필름 생성 저해용 조성물 |
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| EP1729781B1 (en) * | 2004-03-15 | 2012-10-24 | Karaolis, David K. R. | A method for inhibiting cancer cell proliferation or increasing cancer cell apoptosis |
| WO2006073514A2 (en) * | 2004-08-25 | 2006-07-13 | Tufts University | Compositions, methods and kits for repressing virulence in gram positive bacteria |
| EP1782826A1 (en) * | 2005-11-08 | 2007-05-09 | GBF Gesellschaft für Biotechnologische Forschung mbH | PQS and c-diGMP and its conjugates as adjuvants and their uses in pharmaceutical compositions |
| US8343536B2 (en) | 2007-01-25 | 2013-01-01 | Cook Biotech Incorporated | Biofilm-inhibiting medical products |
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| WO2009100456A2 (en) * | 2008-02-08 | 2009-08-13 | Prothera, Inc. | Inhibition and treatment of gastrointestinal biofilms |
| WO2009133560A1 (en) * | 2008-04-29 | 2009-11-05 | Smart Assays | Non-hydrolyzable and permeable cyclic bis-[nucleotide monophosphate] derivatives and uses thereof |
| US20120178710A1 (en) * | 2009-07-01 | 2012-07-12 | Rutgers, The State University Of New Jersey | Synthesis of cyclic diguanosine monophosphate and thiophosphate analogs thereof |
| CN102199183B (zh) * | 2010-03-26 | 2013-12-18 | 北京大学 | 环二鸟苷酸及其类似物和制备方法 |
| CN101843899B (zh) * | 2010-05-24 | 2012-11-07 | 中国人民解放军第三军医大学 | 耐甲氧西林金黄色葡萄球菌（mrsa）重组多亚单位基因工程疫苗及其制备方法 |
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| US8450293B2 (en) | 2010-08-10 | 2013-05-28 | Rutgers, The State University Of New Jersey | Synthesis and characterization of C8 analogs of c-di-GMP |
| CN104507538B (zh) | 2012-06-08 | 2018-04-06 | 艾杜罗生物科技公司 | 癌症免疫疗法的组合物和方法 |
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| US9315523B2 (en) | 2013-12-06 | 2016-04-19 | Rutgers, The State University Of New Jersey | Cyclic dinucleosides |
| PE20170198A1 (es) | 2014-06-04 | 2017-04-08 | Glaxosmithkline Ip Dev Ltd | Dinucleotidos ciclicos como moduladores de sting |
| GB201501462D0 (en) | 2015-01-29 | 2015-03-18 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
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| SG10201912074PA (en) | 2016-03-18 | 2020-02-27 | Immune Sensor Llc | Cyclic di-nucleotide compounds and methods of use |
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| JP7195317B2 (ja) | 2017-11-10 | 2022-12-23 | 武田薬品工業株式会社 | Ｓｔｉｎｇ調節剤化合物、ならびに製造及び使用する方法 |
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| JP2002302404A (ja) * | 2001-04-02 | 2002-10-18 | Shiseido Co Ltd | 抗菌防黴助剤 |
| WO2003059359A1 (en) * | 2001-10-25 | 2003-07-24 | Spherix Incorporated | D-tagatose as an anti-biofilm agent |
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| US20020169288A1 (en) * | 2001-03-15 | 2002-11-14 | Magnus Hook | Collagen-binding adhesin from staphylococcus epidermidis and method of use |
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2004
- 2004-07-22 AU AU2004275696A patent/AU2004275696B2/en not_active Ceased
- 2004-07-22 US US10/565,591 patent/US8367716B2/en not_active Expired - Fee Related
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- 2004-07-22 EP EP04809506A patent/EP1651242A2/en not_active Withdrawn
- 2004-07-22 WO PCT/US2004/023498 patent/WO2005030186A2/en not_active Ceased
- 2004-07-22 CA CA002533873A patent/CA2533873A1/en not_active Abandoned
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- 2006-01-10 IL IL173065A patent/IL173065A/en active IP Right Grant
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| JP2002302404A (ja) * | 2001-04-02 | 2002-10-18 | Shiseido Co Ltd | 抗菌防黴助剤 |
| WO2003059359A1 (en) * | 2001-10-25 | 2003-07-24 | Spherix Incorporated | D-tagatose as an anti-biofilm agent |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014109256A1 (ja) * | 2013-01-09 | 2014-07-17 | 国立大学法人東北大学 | トリアゾール連結型環状ジヌクレオチド類縁体 |
| JP2016531842A (ja) * | 2013-05-18 | 2016-10-13 | アデュロ バイオテック，インコーポレイテッド | 「インターフェロン遺伝子の刺激因子」依存性シグナル伝達を抑制するための組成物および方法 |
| US10189873B2 (en) | 2013-05-18 | 2019-01-29 | Aduro Biotech, Inc. | Compositions and methods for inhibiting “stimulator of interferon gene”-dependent signalling |
| KR20200058411A (ko) * | 2017-08-30 | 2020-05-27 | 베이징 슈안이 파마사이언시스 컴퍼니, 리미티드 | 인터페론 유전자 조절인자의 자극제로서의 환식 다이-뉴클레오타이드 |
| JP2020532585A (ja) * | 2017-08-30 | 2020-11-12 | ベイジン シュエンイー ファーマサイエンシズ カンパニー， リミテッド | インターフェロン遺伝子刺激因子調節薬としての環状ジヌクレオチド |
| JP7311514B2 (ja) | 2017-08-30 | 2023-07-19 | ベイジン シュエンイー ファーマサイエンシズ カンパニー， リミテッド | インターフェロン遺伝子刺激因子調節薬としての環状ジヌクレオチド |
| KR102782200B1 (ko) * | 2017-08-30 | 2025-03-17 | 에이제이 사이언시즈 (이씽) 코., 엘티디 | 인터페론 유전자 조절인자의 자극제로서의 환식 다이-뉴클레오타이드 |
| KR102551061B1 (ko) * | 2022-05-26 | 2023-07-03 | 중앙대학교 산학협력단 | Saha를 유효성분으로 포함하는 살모넬라 속 균주에 의한 바이오필름 생성 저해용 조성물 |
Also Published As
| Publication number | Publication date |
|---|---|
| IL173065A0 (en) | 2006-06-11 |
| US20070244059A1 (en) | 2007-10-18 |
| IL173065A (en) | 2011-05-31 |
| WO2005030186A3 (en) | 2005-07-14 |
| AU2004275696B2 (en) | 2010-02-18 |
| AU2004275696A1 (en) | 2005-04-07 |
| WO2005030186A2 (en) | 2005-04-07 |
| EP1651242A2 (en) | 2006-05-03 |
| US8367716B2 (en) | 2013-02-05 |
| CA2533873A1 (en) | 2005-04-07 |
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