JP2007500205A5 - - Google Patents
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- Publication number
- JP2007500205A5 JP2007500205A5 JP2006531007A JP2006531007A JP2007500205A5 JP 2007500205 A5 JP2007500205 A5 JP 2007500205A5 JP 2006531007 A JP2006531007 A JP 2006531007A JP 2006531007 A JP2006531007 A JP 2006531007A JP 2007500205 A5 JP2007500205 A5 JP 2007500205A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- alkyl group
- mip synthase
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 28
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 11
- 101710113802 Inositol-3-phosphate synthase Proteins 0.000 claims 8
- 101710090028 Inositol-3-phosphate synthase 1 Proteins 0.000 claims 8
- 102100036881 Inositol-3-phosphate synthase 1 Human genes 0.000 claims 8
- 229910052739 hydrogen Inorganic materials 0.000 claims 5
- 239000001257 hydrogen Substances 0.000 claims 5
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 3
- 208000020016 psychiatric disease Diseases 0.000 claims 3
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 210000005171 mammalian brain Anatomy 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 208000020925 Bipolar disease Diseases 0.000 claims 1
- 101000998969 Homo sapiens Inositol-3-phosphate synthase 1 Proteins 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 210000004556 brain Anatomy 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 150000002431 hydrogen Chemical group 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 238000007912 intraperitoneal administration Methods 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 238000007911 parenteral administration Methods 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL15620303A IL156203A0 (en) | 2003-05-29 | 2003-05-29 | Use of 2,2,3,3, tetramethylcyclopropane carboxylic acid derivatives for treating psychiatric disorders |
| PCT/IL2004/000455 WO2004105746A1 (en) | 2003-05-29 | 2004-05-27 | Use of 2,2,3,3, tetramethylcyclopropane carboxylic acid derivatives for treating psychiatric disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007500205A JP2007500205A (ja) | 2007-01-11 |
| JP2007500205A5 true JP2007500205A5 (enExample) | 2007-07-12 |
Family
ID=32587598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006531007A Pending JP2007500205A (ja) | 2003-05-29 | 2004-05-27 | 精神障害を治療するための２，２，３，３，テトラメチルシクロプロパンカルボン酸誘導体の使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20100048721A2 (enExample) |
| EP (1) | EP1626710B1 (enExample) |
| JP (1) | JP2007500205A (enExample) |
| AT (1) | ATE409469T1 (enExample) |
| CA (1) | CA2527094A1 (enExample) |
| DE (1) | DE602004016841D1 (enExample) |
| IL (2) | IL156203A0 (enExample) |
| WO (1) | WO2004105746A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL157751A0 (en) | 2003-02-28 | 2004-03-28 | Yissum Res Dev Co | New amide derivatives of 2,2,3,3-tetramethylcyclopropane carboxylic acid, a method for their synthesis and pharmaceutical compositions containing them |
| US20060004098A1 (en) * | 2003-07-28 | 2006-01-05 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compounds useful for treating neurological disorders |
| CN100426897C (zh) | 2005-01-12 | 2008-10-15 | 华为技术有限公司 | 分体式基站系统及其组网方法和基带单元 |
| CN102198121B (zh) * | 2011-04-08 | 2012-05-23 | 广东药学院 | 2,2,3,3-四甲基环丙酰硫脲在制备抗肿瘤药物中的应用 |
| JP2014515408A (ja) * | 2011-06-03 | 2014-06-30 | エラン ファーマシューティカルズ，リミティド ライアビリティー カンパニー | 行動及び精神障害の治療のためのシロ−イノシトール |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9303274D0 (sv) * | 1993-10-07 | 1993-10-07 | Astra Ab | Novel phenylethyl and phenylproplamines |
| IL108595A (en) * | 1994-02-08 | 1998-09-24 | Yissum Res Dev Co | History of Carboxylic Acid 2,2,3,3 Tetramethyl Cyclophen (ACMT) (Process for their Preparation and Pharmaceutical Preparations Containing Them) |
| PL365588A1 (en) * | 2000-07-21 | 2005-01-10 | Teva Pharmaceutical Industries, Ltd. | Use of derivatives of valproic acid and 2-valproenic acid amides for the treatment of mania in bipolar disorder |
| US6610326B2 (en) * | 2001-02-16 | 2003-08-26 | Andrx Corporation | Divalproex sodium tablets |
| IL147953A (en) * | 2002-02-01 | 2008-04-13 | Meir Bialer | Derivatives and pharmaceutical compositions of n-hydroxymethyl tetramethylcyclopropyl- |
-
2003
- 2003-05-29 IL IL15620303A patent/IL156203A0/xx unknown
-
2004
- 2004-05-27 EP EP04735084A patent/EP1626710B1/en not_active Expired - Lifetime
- 2004-05-27 WO PCT/IL2004/000455 patent/WO2004105746A1/en not_active Ceased
- 2004-05-27 AT AT04735084T patent/ATE409469T1/de not_active IP Right Cessation
- 2004-05-27 CA CA002527094A patent/CA2527094A1/en not_active Abandoned
- 2004-05-27 JP JP2006531007A patent/JP2007500205A/ja active Pending
- 2004-05-27 DE DE602004016841T patent/DE602004016841D1/de not_active Expired - Lifetime
- 2004-05-27 US US10/558,408 patent/US20100048721A2/en not_active Abandoned
-
2005
- 2005-11-23 IL IL172134A patent/IL172134A/en not_active IP Right Cessation