JP2007500171A5 - - Google Patents
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- Publication number
- JP2007500171A5 JP2007500171A5 JP2006521581A JP2006521581A JP2007500171A5 JP 2007500171 A5 JP2007500171 A5 JP 2007500171A5 JP 2006521581 A JP2006521581 A JP 2006521581A JP 2006521581 A JP2006521581 A JP 2006521581A JP 2007500171 A5 JP2007500171 A5 JP 2007500171A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- heteroaryl
- aryl
- alkenyl
- carboxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03102313.8 | 2003-07-28 | ||
| EP03102313 | 2003-07-28 | ||
| PCT/EP2004/051625 WO2005011686A1 (en) | 2003-07-28 | 2004-07-27 | 2-imino-4-(thio) oxo-5-poly cyclovinylazolines for use as p13 kinase ihibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007500171A JP2007500171A (ja) | 2007-01-11 |
| JP2007500171A5 true JP2007500171A5 (https=) | 2007-09-13 |
| JP4908210B2 JP4908210B2 (ja) | 2012-04-04 |
Family
ID=34112474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006521581A Expired - Fee Related JP4908210B2 (ja) | 2003-07-28 | 2004-07-27 | Ｐｉ３キナーゼ阻害剤として使用するための２−イミノ−４−（チオ）オキソ−５−ポリシクロビニルアゾリン類 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8106214B2 (https=) |
| EP (1) | EP1648452B1 (https=) |
| JP (1) | JP4908210B2 (https=) |
| CA (1) | CA2531140C (https=) |
| DE (1) | DE602004022170D1 (https=) |
| ES (1) | ES2328146T3 (https=) |
| IL (1) | IL173195A (https=) |
| NO (1) | NO332434B1 (https=) |
| WO (1) | WO2005011686A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1718642A4 (en) * | 2004-02-25 | 2010-11-24 | Glaxosmithkline Llc | NEW CHEMICAL COMPOUNDS |
| MXPA06015028A (es) | 2004-07-01 | 2007-02-08 | Hoffmann La Roche | Tiazolinas cinolinas no sustituidas. |
| CN101052640B (zh) * | 2004-09-03 | 2011-05-11 | 默克雪兰诺有限公司 | 吡啶亚甲基唑烷酮类及其作为磷酸肌醇抑制剂的用途 |
| US7241893B2 (en) | 2004-09-17 | 2007-07-10 | Hoffman-La Roche Inc. | Thiazolinone 2-substituted quinolines |
| US7253285B2 (en) | 2004-09-17 | 2007-08-07 | Hoffmann-La Roche Inc. | Thiazolinone 4-monosubstituted quinolines |
| CN101039939B (zh) * | 2004-10-14 | 2010-07-07 | 霍夫曼-拉罗奇有限公司 | 作为cdk1抑制剂的喹唑啉基亚甲基噻唑啉酮类 |
| US7304074B2 (en) * | 2005-04-05 | 2007-12-04 | Hoffmann-La Roche Inc. | Substituted 1,5-naphthyridine azolinones |
| PE20070083A1 (es) * | 2005-06-08 | 2007-01-27 | Smithkline Beecham Corp | (5z)-5-(6-quinoxalinilmetilideno)-2-[(2,6-diclorofenil)amino]-1,3-tiazol-4(5h)-ona |
| CN101300047A (zh) * | 2005-09-07 | 2008-11-05 | 雪兰诺实验室有限公司 | Pi3k抑制剂用于子宫内膜异位症的治疗 |
| US20080306057A1 (en) * | 2005-10-11 | 2008-12-11 | Laboratories Serono Sa | P13K Inhibitors for the Treatment of Endometriosis |
| EP1976495A2 (en) * | 2006-01-06 | 2008-10-08 | Aarhus Universitet | Compounds acting on the serotonin transporter |
| WO2007113005A2 (en) * | 2006-04-03 | 2007-10-11 | European Molecular Biology Laboratory (Embl) | 2-substituted 3-aminosulfonyl-thiophene derivatives as aurora kinase inhibitors |
| CL2007000995A1 (es) * | 2006-04-11 | 2008-06-27 | Smithkline Beecham Corp | Compuestos derivados de tiazolidinadiona; composicion farmaceutica; y uso para tratar uno o mas estados de enfermedad seleccionada entre trastornos autoinmunes, enfermedad inflamatoria, cardiovascular y neurodegenerativa entre otras. |
| US20100286041A1 (en) * | 2007-03-22 | 2010-11-11 | Smithkline Beecham Corporation | (5z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl)amino]-1,3-thiazol-4(5h)-one |
| US20080255115A1 (en) * | 2007-04-11 | 2008-10-16 | Michael Gerard Darcy | Thiazolidinedione derivatives as pi3 kinase inhibitors |
| PE20090288A1 (es) * | 2007-05-10 | 2009-04-03 | Smithkline Beecham Corp | Derivados de quinoxalina como inhibidores de la pi3 quinasa |
| PE20090717A1 (es) * | 2007-05-18 | 2009-07-18 | Smithkline Beecham Corp | Derivados de quinolina como inhibidores de la pi3 quinasa |
| FR2919608B1 (fr) * | 2007-08-01 | 2012-10-05 | Univ Rennes | Derives d'imidazolones,procede de preparation et applications biologiques |
| EP2255830A1 (en) | 2008-03-03 | 2010-12-01 | Takeda Pharmaceutical Company Limited | Concomitant drug |
| US20100316639A1 (en) | 2009-06-16 | 2010-12-16 | Genentech, Inc. | Biomarkers for igf-1r inhibitor therapy |
| MX2013000617A (es) * | 2010-07-16 | 2013-06-13 | Piramal Entpr Ltd | Derivados sustituidos de imidazoquinolina como inhibidores de quinasa. |
| CN102584809B (zh) * | 2011-01-14 | 2014-12-24 | 湘北威尔曼制药股份有限公司 | 胺基噻唑烷酮化合物及其制备方法与在制备抗肿瘤药物中的应用 |
| US9745323B2 (en) | 2012-07-30 | 2017-08-29 | Kyoto University | Compound and pharmaceutical composition for neuropsychological disorder or malignant tumor |
| US10310802B2 (en) * | 2014-03-26 | 2019-06-04 | Unanimous A. I., Inc. | System and method for moderating real-time closed-loop collaborative decisions on mobile devices |
| CN106588909B (zh) * | 2017-01-06 | 2019-08-27 | 广东工业大学 | 一种喹啉类衍生物的制备及其在抗炎中的应用 |
| HRP20240793T1 (hr) | 2018-04-18 | 2024-09-13 | Constellation Pharmaceuticals, Inc. | Modulatori enzima koji modificiraju metil, njihovi pripravci i upotreba |
| EP3797108B1 (en) | 2018-05-21 | 2022-07-20 | Constellation Pharmaceuticals, Inc. | Modulators of methyl modifying enzymes, compositions and uses thereof |
| LT4003532T (lt) | 2019-07-24 | 2024-11-11 | Constellation Pharmaceuticals, Inc. | 7-chlor-2- (4-(3-metoksiazetidin-1-il)cikloheksil)-2,4-dimetil-n-((6-metil-4-(metiltio)-2-okso-1,2-dihidropiridin-3-il)metil)benzo[d][1,3]dioksol-5-karboksamido kristalinės formos |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH052200A (ja) | 1990-09-28 | 1993-01-08 | Toshiba Corp | 有機非線形光学材料 |
| JP3871354B2 (ja) * | 1994-07-29 | 2007-01-24 | 株式会社フジモト・コーポレーション | 新規な２−（ｎ−シアノイミノ）チアゾリジン−４−オン誘導体 |
| JP4782564B2 (ja) | 2002-07-10 | 2011-09-28 | メルク セローノ ソシエテ アノニム | アゾリジノン−ビニル縮合−ベンゼン誘導体 |
| CN100579978C (zh) * | 2002-11-22 | 2010-01-13 | 史密丝克莱恩比彻姆公司 | 化合物 |
| CN101052640B (zh) | 2004-09-03 | 2011-05-11 | 默克雪兰诺有限公司 | 吡啶亚甲基唑烷酮类及其作为磷酸肌醇抑制剂的用途 |
-
2004
- 2004-07-27 ES ES04766335T patent/ES2328146T3/es not_active Expired - Lifetime
- 2004-07-27 CA CA2531140A patent/CA2531140C/en not_active Expired - Fee Related
- 2004-07-27 JP JP2006521581A patent/JP4908210B2/ja not_active Expired - Fee Related
- 2004-07-27 DE DE602004022170T patent/DE602004022170D1/de not_active Expired - Lifetime
- 2004-07-27 US US10/565,976 patent/US8106214B2/en not_active Expired - Fee Related
- 2004-07-27 EP EP04766335A patent/EP1648452B1/en not_active Expired - Lifetime
- 2004-07-27 WO PCT/EP2004/051625 patent/WO2005011686A1/en not_active Ceased
-
2006
- 2006-01-17 IL IL173195A patent/IL173195A/en not_active IP Right Cessation
- 2006-02-03 NO NO20060573A patent/NO332434B1/no not_active IP Right Cessation
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