JP2007500160A - 癌の予防および治療のための置換イミダゾピリミジン - Google Patents

癌の予防および治療のための置換イミダゾピリミジン Download PDF

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Publication number
JP2007500160A
JP2007500160A JP2006521521A JP2006521521A JP2007500160A JP 2007500160 A JP2007500160 A JP 2007500160A JP 2006521521 A JP2006521521 A JP 2006521521A JP 2006521521 A JP2006521521 A JP 2006521521A JP 2007500160 A JP2007500160 A JP 2007500160A
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JP
Japan
Prior art keywords
pyrimidine
methylsulfanylphenyl
imidazo
cancer
methoxyphenyl
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Withdrawn
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JP2006521521A
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English (en)
Japanese (ja)
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JP2007500160A5 (https=
Inventor
フアン・ロレンソ・カテナ・ルイス
カルレス・ファレロンス・ガリェミ
アンナ・フェルナンデス・セラト
カルメン・セラ・コマス
ドロルス・バルサ・ロペス
カルメン・ラグナス・アルナル
カロリナ・サルセド・ロカ
アンドレス・フェルナンデス・ガルシア
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Laboratorios Salvat SA
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Laboratorios Salvat SA
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Publication date
Application filed by Laboratorios Salvat SA filed Critical Laboratorios Salvat SA
Publication of JP2007500160A publication Critical patent/JP2007500160A/ja
Publication of JP2007500160A5 publication Critical patent/JP2007500160A5/ja
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2006521521A 2003-07-30 2004-07-29 癌の予防および治療のための置換イミダゾピリミジン Withdrawn JP2007500160A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200301906 2003-07-30
PCT/EP2004/008476 WO2005014598A1 (en) 2003-07-30 2004-07-29 Substituted imidazopyrimidines for the prevention and treatment of cancer

Publications (2)

Publication Number Publication Date
JP2007500160A true JP2007500160A (ja) 2007-01-11
JP2007500160A5 JP2007500160A5 (https=) 2007-09-20

Family

ID=34130555

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006521521A Withdrawn JP2007500160A (ja) 2003-07-30 2004-07-29 癌の予防および治療のための置換イミダゾピリミジン

Country Status (14)

Country Link
US (1) US20060189631A1 (https=)
EP (1) EP1660500B1 (https=)
JP (1) JP2007500160A (https=)
KR (1) KR20060034303A (https=)
CN (1) CN1860121A (https=)
AT (1) ATE380816T1 (https=)
AU (1) AU2004263297A1 (https=)
BR (1) BRPI0412636A (https=)
CA (1) CA2534292A1 (https=)
DE (1) DE602004010680T2 (https=)
EA (1) EA009038B1 (https=)
ES (1) ES2298798T3 (https=)
WO (1) WO2005014598A1 (https=)
ZA (1) ZA200601706B (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007096764A2 (en) * 2006-02-27 2007-08-30 Glenmark Pharmaceuticals S.A. Bicyclic heteroaryl derivatives as cannabinoid receptor modulators
US7683060B2 (en) 2006-08-07 2010-03-23 Incyte Corporation Triazolotriazines as kinase inhibitors
ME02372B (me) 2006-11-22 2016-06-20 Incyte Holdings Corp Imidazotriazini i imidazopiramidini kao inhibitori kinaze
EP2062893A1 (en) * 2007-10-18 2009-05-27 Bayer Schering Pharma AG Fused imidazoles for cancer treatment
UY31292A1 (es) * 2007-08-14 2009-03-31 Imidazoles biciclicos fusionados
WO2009143211A2 (en) 2008-05-21 2009-11-26 Incyte Corporation Salts of 2-fluoro-n-methyl-4-[7-(quinolin-6-yl-methyl)- imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide and processes related to preparing the same
MX2012004341A (es) 2009-10-16 2012-10-05 Rib X Pharmaceuticals Inc Compuestos antimicrobianos y metodos para fabricar y utilizar los mismos.
EA025304B1 (ru) 2010-02-03 2016-12-30 Инсайт Холдингс Корпорейшн ИМИДАЗО[1,2-b][1,2,4]ТРИАЗИНЫ В КАЧЕСТВЕ c-Met ИНГИБИТОРОВ
US8410117B2 (en) * 2010-03-26 2013-04-02 Hoffmann-La Roche Inc. Imidazopyrimidine derivatives
SI2694510T1 (sl) 2011-04-07 2016-02-29 Bayer Intellectual Property Gmbh Imidazopiridazini kot inhibitorji AKT kinaze
CN102796103A (zh) * 2011-05-23 2012-11-28 南京英派药业有限公司 6-（芳基甲酰）咪唑并[1,2-a]嘧啶和6-（芳基甲酰）[1,2,4]三唑并[4,3-a]嘧啶作为Hedgehog抑制剂及其应用
UY35400A (es) * 2013-03-15 2014-10-31 Novartis Ag Compuestos y composiciones para el tratamiento de enfermedades parasitarias
US9296754B2 (en) 2013-03-15 2016-03-29 Novartis Ag Compounds and compositions for the treatment of parasitic diseases
US9233961B2 (en) 2013-03-15 2016-01-12 Novartis Ag Compounds and compositions for the treatment of parasitic diseases
US9186361B2 (en) 2013-03-15 2015-11-17 Novartis Ag Compounds and compositions for the treatment of parasitic diseases
TWI674263B (zh) 2013-12-19 2019-10-11 瑞士商諾華公司 用於治療寄生蟲疾病之化合物及組合物
HK1249758A1 (zh) 2015-03-11 2018-11-09 Melinta Therapeutics, Inc. 抗微生物化合物及其制备和使用方法
US11098047B2 (en) 2016-05-06 2021-08-24 BioVersys AG Antimicrobials and methods of making and using same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3455924A (en) * 1967-02-08 1969-07-15 Upjohn Co Dianisylimidazoles
US5700826A (en) * 1995-06-07 1997-12-23 Ontogen Corporation 1,2,4,5-tetra substituted imidazoles as modulators of multi-drug resistance
ES2140354B1 (es) * 1998-08-03 2000-11-01 S A L V A T Lab Sa Imidazo (1,2a) azinas sustituidas como inhibidores selectivos de la cox-2.

Also Published As

Publication number Publication date
EA009038B1 (ru) 2007-10-26
DE602004010680T2 (de) 2009-01-02
ZA200601706B (en) 2007-09-26
ATE380816T1 (de) 2007-12-15
BRPI0412636A (pt) 2006-09-26
EP1660500A1 (en) 2006-05-31
WO2005014598A1 (en) 2005-02-17
EA200600330A1 (ru) 2006-08-25
KR20060034303A (ko) 2006-04-21
AU2004263297A1 (en) 2005-02-17
DE602004010680D1 (de) 2008-01-24
US20060189631A1 (en) 2006-08-24
ES2298798T3 (es) 2008-05-16
EP1660500B1 (en) 2007-12-12
CN1860121A (zh) 2006-11-08
CA2534292A1 (en) 2005-02-17

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