JP2007159549A - Health food composition of processed food of angelica keiskei and amino acid - Google Patents

Health food composition of processed food of angelica keiskei and amino acid Download PDF

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JP2007159549A
JP2007159549A JP2005380953A JP2005380953A JP2007159549A JP 2007159549 A JP2007159549 A JP 2007159549A JP 2005380953 A JP2005380953 A JP 2005380953A JP 2005380953 A JP2005380953 A JP 2005380953A JP 2007159549 A JP2007159549 A JP 2007159549A
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tomorrow
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Fuminori Kawabata
史典 川端
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Fuji Shoji Co Ltd
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Fuji Shoji Co Ltd
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Abstract

<P>PROBLEM TO BE SOLVED: To obtain a health food composition that maintains, promotes and ameliorates human health by anti-gastric ulcer action, gastric acid secretion inhibitory action, blood flow promotion action and blood pressure reduction action by administering a mixed composition of a processed product of Angelica keiskei and an amino acid to a living body. <P>SOLUTION: The health food composition is obtained by mixing Angelica keiskei expressing anti-ulcer action, gastric acid secretion inhibitory action and peripheral vasodilator action with an amino acid expressing ulcer healing quality, blood flow promotion action and blood pressure reduction action and is expected to have additive or synergistic effects of both the components besides efficacies of the individual components by administration of the composition. <P>COPYRIGHT: (C)2007,JPO&INPIT

Description

本発明は人々の健康の維持、増進、改善を図るために明日葉加工品とアミノ酸の有効成分を主体とする健康食品組成物に関する。  The present invention relates to a health food composition mainly composed of a processed product of tomorrow and an active ingredient of amino acids in order to maintain, enhance and improve people's health.

健康増進法が施行され、人々の健康に対する欲求が高まっており、巷には健康食品と言われるものが溢れている。世界各地から効果効能があると言われている原料を使用した健康食品が年々増加しており、日本人にとって馴染みのない或いは初めて聞くような動植物由来原料の製品が多く見られる。  Health promotion law has been enforced, people's desire for health is increasing, and soot is full of what is called health food. Health foods using ingredients that are said to have effective effects from around the world are increasing year by year, and there are many products of animal and plant-derived ingredients that are unfamiliar to Japanese or heard for the first time.

人々が健康の維持、増進、改善を図るための健康食品組成物とは、安全性、効果効能が確認されているのは当然であるが、日本人が昔より食しており、食経験が豊かで長期にわたって食され、その上薬効、効能をも昔より生活の上で利用されている原料は尚安心である。  It is natural that the health food composition has been confirmed to be safe, effective and effective for maintaining, enhancing and improving health. Ingredients that have been eaten over a long period of time and that have been used in daily life due to their medicinal properties and effects are still safe.

また、食品の前提として栄養素のバランスの組合せの良いものが求められる。特に植物由来原料の場合、ビタミン、ミネラルは豊富に含まれているがたんぱく質(アミノ酸)は相対的に低い。本発明は上記のような条件を満たし、且つ強化された健康食品組成物を提供する点にある。  In addition, a food with a good combination of nutrient balances is required as a food premise. Particularly in the case of plant-derived materials, vitamins and minerals are abundant, but proteins (amino acids) are relatively low. The present invention is to provide a health food composition that satisfies the above-described conditions and is enhanced.

本発明は人々の健康維持、増進、改善を図る可能性のある原料、配合の検討をし、情報を収集した。その結果、抗胃潰瘍作用、胃酸分泌抑制作用、末梢血管拡張作用を最大の特徴とする明日葉と、潰瘍治癒能、血流改善、血圧低下能を特徴とするアミノ酸を最適に組合せた組成物は体内においてそれぞれ個別で有する効果効能を上回る効果が期待される。  In the present invention, raw materials and blends that have the potential to maintain, improve and improve people's health were studied and information was collected. As a result, an optimal combination of tomorrow, which has the greatest anti-gastric ulcer activity, gastric acid secretion inhibitory activity, and peripheral vasodilatory activity, with amino acids characterized by ulcer healing ability, blood flow improvement, and blood pressure lowering ability, Expected to be more effective than individual effects in the body.

明日葉加工品にアミノ酸を組合せることで、栄養バランスが格段に改善され、しかも明日葉加工品とアミノ酸の併用という健康食品組成物は、従来にない組合せである。即ち本発明は明日葉加工品とアミノ酸の健康食品組成物である。  By combining amino acids with processed tomorrow products, the nutritional balance is remarkably improved, and the health food composition of combining processed tomorrow products with amino acids is an unprecedented combination. That is, the present invention is a processed food product of tomorrow and an amino acid health food composition.

抗潰瘍作用、胃酸分泌抑制作用、末梢血管拡張作用を最大の特徴とする明日葉について詳述する。明日葉は日本固有のセリ科Angelica(シシウド属)の大型多年生草木であり、房総半島、三浦半島、伊豆半島、伊豆諸島、紀伊半島に自生する。江戸時代にはアシタグサ、アイダグサ、ハチジョウソウと呼ばれ天然痘の予防に用いられていたという。  The details of tomorrow, which has the most anti-ulcer action, gastric acid secretion inhibitory action, and peripheral vasodilatory action, will be described. Tomorrow is a large perennial vegetation of Japan's unique celery family Angelica, which grows naturally on the Boso Peninsula, Miura Peninsula, Izu Peninsula, Izu Islands, and Kii Peninsula. In the Edo period, it was called Ashitagusa, Idagusa, Hachijosou and used to prevent smallpox.

次に明日葉の生体に対する効能について述べると、明日葉の茎を切断した時に切断面より黄汁が出るのが特徴であるが、この黄汁中には明日葉特有の成分であるカルコンが含まれている。明日葉特有のカルコンとしてキサントアンゲロールと4−ヒドロキシデリシンという2種類のカルコン誘導体が知られている。胃酸分泌抑制作用や抗酸化作用、抗腫瘍作用などが報告されている。  Next, the effect of tomorrow on the body is characterized by the fact that yellow leaves from the cut surface when the stem of tomorrow is cut. This yellow juice contains chalcone, a component unique to tomorrow. It is. As chalcones peculiar to tomorrow, two types of chalcone derivatives, xanthoangelol and 4-hydroxyderricin, are known. Gastric acid secretion inhibitory action, antioxidant action, antitumor action, etc. have been reported.

ここで明日葉の健康作用について詳細を述べる。明日葉が含有するキサントアンゲロールに胃酸分泌抑制、抗腫瘍作用がある。胃の細胞壁における胃酸分泌機構は、微絨毛に存在するプロトンポンプによってHClが生成され胃内腔に分泌される。このプロトンポンプをキサントアンゲロールが阻害し、刺激酸分泌を強力にしかも長時間抑制することにより胃酸分泌抑制、抗胃潰瘍作用が発現する。  The details of the health effects of tomorrow are described here. Xanthoangelol contained in tomorrow has gastric acid secretion suppression and antitumor effects. In the gastric acid secretion mechanism in the cell wall of the stomach, HCl is generated and secreted into the gastric lumen by a proton pump present in the microvilli. This proton pump is inhibited by xanthoangelol and strongly suppresses stimulated acid secretion for a long time, thereby suppressing gastric acid secretion and anti-gastric ulcer action.

次に明日葉に含有するキサントアンゲロール、4−ヒドロキシデリシンによる血流促進作用である。血栓ができる要因として多々あるが、その中でもトロンボキサンA2という物質はアラキドン酸代謝物の1つで血小板凝集や血管の平滑筋収縮作用を持ち、血流阻害の大きな要因となる。このトロンボキサンA2の生成をキサントアンゲロール、4−ヒドロキシデリシンが抑制する。その結果、血栓を防ぎ、血管を拡張(弛緩)することにより血圧も低下し、血流促進される。  Next, the blood flow promoting action by xanthoangelol and 4-hydroxyderricin contained in tomorrow leaves. There are many factors that can cause thrombosis. Among them, the substance called thromboxane A2 is one of the metabolites of arachidonic acid, and has platelet aggregation and blood vessel smooth muscle contraction action, which is a major factor of blood flow inhibition. Xanthoangelol and 4-hydroxyderricin suppress the production of thromboxane A2. As a result, blood pressure is lowered by preventing blood clots and dilating (relaxing) blood vessels, thereby promoting blood flow.

上述以外にも明日葉には食物繊維、ビタミン、ミネラルが豊富に含まれており、便秘の解消や予防、カリウムによる代謝の活性など効果効能があげられる。日本人が昔より食経験があり、地方によっては民間薬として利用されていた歴史があるので安全性は実証されており、現在でも葉や茎をミキサーがけしてジュースとして飲したり天ぷら、おひたし、また小麦粉使用食品(麺、パン、まんじゅう)に練り込まれて健康機能以外にも味や色が食生活に彩りを与えている。  In addition to the above, tomorrow leaves are rich in dietary fiber, vitamins, and minerals, and are effective in eliminating and preventing constipation and metabolic activity by potassium. Japanese people have been eating for a long time, and there is a history of being used as a folk medicine in some regions, so safety has been proven, and even today, leaves and stems are mixed and drunk as juice, tempura, Oitashi In addition, it is kneaded into foods using flour (noodles, bread, manju), and in addition to its health function, its taste and color add color to its diet.

次に潰瘍治癒能、血流改善、血圧低下など様々な健康機能を有するアミノ酸について述べる。現在アミノ酸を謳った食品はアスリートに限らず一般の人々も利用されている。当初はアスリートの持久力アップや疲労回復、筋肉増強など特定の目的を持った人々に利用されていた。その確かな効果が国際的なスポーツ大会などで実証されると徐々に普段スポーツをしない人々にまでアミノ酸が認知されてきた。アミノ酸の中でもアルギニン、グルタミン、バリン、ロイシン、イソロイシンの5種に関しては、運動中のエネルギー源や筋肉の疲労回復などスポーツに関連した効果、効能が知られているが、それ以外にも我々人間の健康維持、増進、改善に大きな役割をはたす働きがある。  Next, amino acids having various health functions such as ulcer healing ability, blood flow improvement, and blood pressure reduction will be described. At present, foods containing amino acids are not limited to athletes but are also used by the general public. Initially, it was used by people with specific purposes such as increasing the endurance of athletes, recovering from fatigue, and strengthening muscles. When its positive effects were demonstrated at international sporting events, amino acids were gradually recognized by people who do not normally play sports. Among amino acids, arginine, glutamine, valine, leucine, and isoleucine are known to have effects and benefits related to sports such as energy sources during exercise and muscle fatigue recovery. It plays a major role in maintaining, improving and improving health.

アルギニンは身体の中で一酸化窒素(NO)を生成する。一酸化窒素は血管を広げ血液が固まるのを防いで血流の流れを良くし、動脈硬化を防ぐ。また一酸化窒素は活性酸素を消去し、免疫力を強化する。この作用により防御因子が増強され、消化性潰瘍の予防や改善効果が得られる。  Arginine produces nitric oxide (NO) in the body. Nitric oxide widens blood vessels and prevents blood from solidifying, improving blood flow and preventing arteriosclerosis. Nitric oxide also scavenges active oxygen and strengthens immunity. This action enhances protective factors, and can prevent or improve peptic ulcer.

グルタミンは必須アミノ酸ではないが、医療用として重要視されているアミノ酸である。手術後の患者の体力を維持し、筋肉を失わせないようにグルタミンを含んだ点滴が栄養補給と筋力維持を目的として使われている。グルタミンは筋肉に限らず、胃や腸などの細胞の増殖を高める働きがあるので、胃酸過多や潰瘍などによって傷ついた胃の粘膜を保護する働きがある。  Glutamine is not an essential amino acid, but is an amino acid that is regarded as important for medical use. Infusions containing glutamine are used to maintain nutrition and maintain strength in order to maintain the physical strength of the patient after surgery and not to lose muscle. Glutamine is not limited to muscles, and has the function of increasing the proliferation of cells such as the stomach and intestines, and therefore has a function of protecting the stomach mucosa damaged by excessive gastric acidity or ulcers.

バリン、ロイシン、イソロイシンは分岐鎖アミノ酸(BCAA)と呼ばれ筋繊維を構成する蛋白質の主成分である。筋繊維以外の組織に関しても修復能があり、免疫力の向上にも働くアミノ酸である。  Valine, leucine, and isoleucine are called branched chain amino acids (BCAA) and are the main components of the proteins that make up muscle fibers. It is an amino acid that has a repairing ability for tissues other than muscle fibers and also works to improve immunity.

以上のように抗潰瘍、胃酸分泌抑制、末梢血管拡張作用の重要な役割を有することを特徴とする明日葉加工品と潰瘍治癒能、血流改善、血圧低下作用を最大の特徴とするアミノ酸は、効果効能は同じであるが、その作用機序に違いがある。両者が別の過程を経ながら、且つ目的は同じであるが故に、同時に体内に摂取することは明日葉加工品、アミノ酸を個別に摂取する効果以上に相加的もしくは相乗的効果が期待される。  As mentioned above, processed tomorrow products that have an important role in anti-ulcer, gastric acid secretion suppression, peripheral vasodilatory action and amino acids with the greatest features of ulcer healing ability, blood flow improvement, blood pressure lowering action are The effect is the same, but the mechanism of action is different. Since both of them go through different processes and the purpose is the same, taking into the body at the same time is expected to have an additive or synergistic effect over the effect of taking tomorrow's processed products and amino acids individually .

本発明における明日葉加工品とアミノ酸を主体とする健康食品組成物を健康食品として或いは健康飲料として請求項1或いは請求項2の範囲内で調整した組成物を麺類、クッキー、ビスケット、パン、ケーキ、ゼリー、ムースその他の食品に、また清涼飲料、乳酸飲料その他種々の飲料に添加しても良い。また製剤として粉剤、顆粒剤、錠剤及びカプセル剤いずれの形態に加工して用いてもよい。  The noodles, cookies, biscuits, bread, cakes, and the compositions prepared within the scope of claim 1 or 2 as health foods or health drinks, the health food composition mainly composed of processed tomorrow and amino acids in the present invention , Jelly, mousse and other foods, soft drinks, lactic acid beverages and other various beverages. Moreover, you may process and use as a formulation in any form of a powder agent, a granule, a tablet, and a capsule.

本発明の明日葉加工品とアミノ酸の健康食品組成物を食品、飲料水等に添加或いは製剤として利用することにより、抗潰瘍作用、胃酸分泌抑制作用、血流改善、血圧低下効果が得られ、その結果、人々の健康を維持、増進、改善を図ることが可能となる。  By using the processed food product of tomorrow and the amino acid health food composition of the present invention in foods, drinking water, etc. or using it as a preparation, antiulcer action, gastric acid secretion inhibitory action, blood flow improvement, blood pressure lowering effect can be obtained, As a result, people's health can be maintained, enhanced, and improved.

実施例1
明日葉粉末3gにL−アルギニン150mg、L−グルタミン200mgに水またはお湯を併せて100mlとし、胃に不快感を感じている5人に、1日2回摂取させた。
明日葉特有の青臭さはあるもののそれ程気にならず、またアミノ酸の苦味も多少感じたが、むしろ爽快さが残る味であり、飲んだ後に胃の不快感が緩和されたとの意見が5人中3人から得られた。
Example 1
Tomorrow's powder 3 g L-arginine 150 mg, L-glutamine 200 mg combined with water or hot water to make 100 ml, and 5 people who feel discomfort in the stomach were ingested twice a day.
Although there is a blue odor peculiar to tomorrow, I didn't care much, and I felt some bitterness of amino acids, but rather a refreshing taste, and five people said that the stomach discomfort was alleviated after drinking Obtained from 3 of them.

実施例2
明日葉粉末4gにL−バリン、L−ロイシン、L−イソロイシンの3種合わせて600mgになるように調整し、食パン製造の小麦粉の1部を置き換えて、定法とおり製造した。
明日葉の緑の生地で明日葉の風味が残り、アミノ酸特有の味は感じられず美味な明日葉食パンであるとの結果を得た。
Example 2
It adjusted so that it might be set to 600 mg combining 3 types of L-valine, L-leucine, and L-isoleucine with 4 g of tomorrow leaf powder, and 1 part of the flour of bread making was replaced, and it manufactured as usual.
As a result, the flavor of tomorrow remained in the green dough of tomorrow, and the taste unique to amino acids was not felt.

Claims (3)

明日葉加工品とアルギニン、グルタミン、バリン、ロイシン、イソロイシンの少なくとも1種類以上のアミノ酸を含有する健康食品組成物  A health food composition containing a processed product of tomorrow and at least one amino acid of arginine, glutamine, valine, leucine and isoleucine 明日葉粉末、明日葉抽出エキス、明日葉ペーストなど明日葉加工品のうち、少なくとも1種類以上からなる加工品とアルギニン、グルタミン、バリン、ロイシン、イソロイシンのうち、少なくとも1種類以上のアミノ酸を含有する健康食品組成物  It contains at least one amino acid of arginine, glutamine, valine, leucine, and isoleucine among processed products of at least one of the processed products of tomorrow such as tomorrow leaf powder, tomorrow extract, and tomorrow leaf paste. Health food composition 請求項1、2に記載のアミノ酸は、1種類以上のアミノ酸総量として50mg以上配合されることを特徴とする健康食品組成物  The amino acid according to claim 1 or 2 is blended in an amount of 50 mg or more as a total amount of one or more amino acids.
JP2005380953A 2005-12-14 2005-12-14 Health food composition of processed food of angelica keiskei and amino acid Pending JP2007159549A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104664369A (en) * 2015-01-14 2015-06-03 厦门医学高等专科学校 Angelica keiskei health food capable of reducing blood pressure and uric acid and preparation method of angelica keiskei health food
JP2016033131A (en) * 2014-07-29 2016-03-10 国立大学法人 筑波大学 Sperm function improving agent, and pharmaceutical compositions, feed, food compositions containing the same, as well as sperm function improving method for domestic animals and fowls
JP2021195354A (en) * 2020-06-18 2021-12-27 有限会社島屋 Vascular endothelial cell activation composition

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016033131A (en) * 2014-07-29 2016-03-10 国立大学法人 筑波大学 Sperm function improving agent, and pharmaceutical compositions, feed, food compositions containing the same, as well as sperm function improving method for domestic animals and fowls
CN104664369A (en) * 2015-01-14 2015-06-03 厦门医学高等专科学校 Angelica keiskei health food capable of reducing blood pressure and uric acid and preparation method of angelica keiskei health food
JP2021195354A (en) * 2020-06-18 2021-12-27 有限会社島屋 Vascular endothelial cell activation composition

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