JP2007119366A - Method for sterilizing trichophyton - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a method for sterilizing Trichophyton, which can usually be used, especially a method for sterilizing Trichophyton, in which the Trichophyton is sterilized with the smoking gas of molded incense. <P>SOLUTION: This method for sterilizing Trichophyton comprises exposing to the smoking gas of molded incense to sterilize. The method for sterilizing the Trichophyton, wherein the molded incense contains bamboo powder. <P>COPYRIGHT: (C)2007,JPO&INPIT

Description

  The present invention relates to a method for sterilizing ringworm fungus, and more particularly to a method for sterilizing ringworm fungus characterized by being sterilized by exposure to smoke gas of molded musk.

  Ringworm fungus is well known as a causative agent of skin diseases such as head ringworm (Shirakumo), body ringworm (Coleoptera), tinea tinea (Coleoptera), ringworm (footworm), ringworm ringworm, hand ringworm, especially athlete's foot It is said that one out of every five Japanese people is athlete's foot. A typical example of ringworm is a microorganism of the genus Arthroderma (also known as the genus Trichophyton). Athlete's foot is easily infected via shoes, boots, sandals, socks, foot wipes, and the like, and a method for sterilizing ringworm bacteria adhering to these articles is desired.

  On the other hand, molded musk has been conventionally used as an incense stick for Buddhist affairs or as a material for burning and flavoring to obtain a relaxing and healing effect. Molded musk is usually milled from the bark (cuttlefish) bark (cuttlefish), which is an evergreen Takagi of the family camphoraceae, and the powdered or tabulated leaf powder called glue powder. A mixture of leaves and bark pulverized product is the main ingredient, mixed with fragrant wood powder, fragrance, pigment, etc., mixed with water (usually hot water), shaped into various shapes, Manufactured dry.

  Molded musk used to control insects by volatilizing pyrethroids, which are insecticidal components of insecticide chrysanthemums, together with smoke gas generated by burning in a flame-free state, such as mosquito coils that have been used for a long time Is also known. However, apart from the mosquito coils developed for the purpose of preventing insects, there has been almost no controversial discussion on the biological action of soot gas.

  In view of the present situation, the present invention is intended to provide a method for sterilizing ringworm fungi that can be used on a daily basis, and in particular, a method for sterilizing ringworm fungi characterized by sterilization using smoked gas of molded musk. It is.

  The present inventor paid attention to the use of molded scented incense, and as a result of extensive research, it turned out that the smoke gas of molded scented smoke, especially the molded scented smoke containing bamboo powder, is effective in sterilizing ringworm bacteria. did.

  That is, this invention solves the said subject by providing the sterilization method of the ringworm bacteria characterized by exposing and sterilizing by the smoke gas of shaping | molding musk.

  The method for sterilizing ringworm fungus according to the present invention utilizes the smoked gas of molded musk so that it can be easily carried out, and ringworm that is an infection source of skin diseases such as athlete's foot attached to articles used on a daily basis. It is useful for sterilizing fungi and thus preventing infection of ringworms in the human body.

  The present invention relates to a method for sterilizing ringworm fungi utilizing the bactericidal action of ringworm bacteria possessed by smoked gas of molded musk. The method for sterilizing ringworm fungus of the present invention comprises water (usually hot water) that is a main powder that is a ground bark pulverized product and a ground powder that is a ground leaf pulverized product or a mixture of leaf and bark pulverized material. ) And mixed with fragrant wood powder or other auxiliary materials, molded and dried, and usually sterilized by exposing the target article to the smoked gas of molded smoked smoke containing bamboo powder. It is characterized by doing.

  The content of bamboo powder in the bamboo powder containing bamboo powder used in the present invention is usually 25% by mass or more and 95% by mass or less, and preferably 30% by mass or more and 90% by mass or less. If the bamboo powder content exceeds 95% by mass, the content of the binder base material such as main flour and paste will be less than 5% by mass, so that the physical strength of the molded musk will be reduced, making molding difficult? Or, shape retention after molding and drying becomes difficult.

  Molded musk used in the present invention is blended with a naturally occurring fragrance or synthetic fragrance as an auxiliary material, as long as the smoke gas does not interfere with the intended purpose of exhibiting the bactericidal action of ringworm. There may be. Naturally derived fragrances include mandala, scented incense, sandalwood, cinnamon bark, clove, sweet pine incense, licorice incense, territory, turmeric, daikon incense, milk incense, dragon brain, aoki incense, zero ling incense, pill, Yamana, benzoin, Sone Sliced, crushed, pulverized, and cuts, crushed and crushed of hardwood or coniferous trees such as camphor, cedar and pine, Examples include cuts, crushed materials, and pulverized products of fragrances derived from animals such as dragon scent and shellfish. In addition, extracts that are extracts of these aromatic substances, natural fragrances such as herb extract, eucalyptus extract, rose oil, lavender oil, propolis extract, synthetic fragrances such as menthol, geraniol, vanillin, and more Even if it uses what combined the seed | species or 2 or more types suitably, it can utilize advantageously.

  In addition to the above components, the molded musk used in the present invention is generally used for ordinary molded musk as long as the smoke gas does not interfere with the intended purpose of showing the bactericidal action of ringworm bacteria. For example, excipients such as inorganic salts, stabilizers, solvents, binders, colorants, antibacterial agents, preservatives, emulsifiers and the like may be appropriately blended.

  The shape of the molded musk used in the present invention is not particularly limited. For example, granular, spherical, prismatic, pyramid, cylindrical, cone, cube, cuboid, spiral, coil, horseshoe, etc. Can be appropriately selected.

  The method for sterilizing ringworm fungus of the present invention as described above is a method for sterilizing ringworm fungus in various rooms or articles by raising the smoke gas of molded musk and evaporating it in the room or by pouring it into the article. Can be expected.

  Hereinafter, the present invention will be specifically described based on examples.

<Bactericidal action of ringworms of smoke gas of molded musk>
Using the prepared bamboo powder-containing molded incense and commercially available molded incense, the anti-tinea fungus action of these soot gases was examined.

<Example 1-1: Preparation of cone-shaped molded musk with bamboo powder>
First, corn type molded musk with bamboo powder was prepared. That is, 73 parts by mass of bamboo mash powder (trade name “Takequinone Powder”, manufactured by Foodtech Co., Ltd.), 22 parts by mass of paste powder (manufactured by Tennendo Co., Ltd.) and pullulan (trade name “Pullulan PF-”) 10 ", Hayashibara Shoji Co., Ltd.) After mixing 5 parts by mass uniformly, add hot water and knead, compress and extrude into a cone shape and dry naturally according to a conventional method, and weigh about 0. A cone-shaped molded incense with bamboo powder having a diameter of about 10 g and a height of about 20 mm was prepared.

<Example 1-2: Effect of corn-type molded incense with bamboo powder and commercially available molded incense on smoke ring-shaped fungus>
The test for examining the effect of smoked smoke on the tinea fungus was performed as follows. First, as a test strain, Arthroderma benhamiae (also known as Trichophyton mentagrophytes) JCM1885 strain, which is a representative ringworm of many Japanese, is selected in advance. Cultivate on potato dextrose agar (Nissui Pharmaceutical Co., Ltd.) slant medium at 27 ° C. for 6 days, add 5 ml of sterile physiological saline to suspend the spores, and filter by a funnel containing absorbent cotton. A suspension was prepared. Next, the spore suspension was appropriately diluted, and then 0.1 ml was uniformly applied to a potato dextrose agar (Nissui Pharmaceutical Co., Ltd.) plate medium. The plate medium was aseptically placed in a sterilized cylindrical sealed container (anaerobic jar, Nippon Becton Dickinson Co., Ltd., capacity: about 8.5 L), and about 0.08 g of the ignited test molded musk was sealed. The container was put in the bottom of the container and quickly sealed, and the molded musk was burned completely without any flame. The test strain was cultured at 27 ° C. for 96 hours in a sealed state and filled with smoke gas, and the number of colonies that appeared on the plate medium was counted. Further, the plate medium after measurement was taken out of the sealed container, and further cultured at 27 ° C. for 120 hours under the condition without soot gas, and the number of colonies that appeared on the plate medium was counted again. In addition, without using molded musk in a sealed container, and using the same culture under conditions without smoke gas as a control, the number of colonies appearing in the control plate medium is 100%, The colony appearance rate (%) when exposed to soot gas, or when further cultured for 120 hours under the condition without soot gas was evaluated.

  As the molded incense, the test was conducted using two kinds of corn-type molded incense containing bamboo powder obtained in Example 1-1 and one type of commercially available molded incense (commercially molded incense 1: manufactured by Company A). Table 1 shows the results of culturing for 96 hours in a state where the soot gas is filled, and the results of culturing for 120 hours in an open state in the absence of soot gas.

  Filled with smoke gas of molded musk, cultivated ringworm fungus in a sealed state, and compared the colony appearance rate, as seen in the results of Table 1, both molded powdered bamboo incense and commercially available molded musk The relative colony appearance rate was 0%, and no growth of ringworm was observed, and it was proved to have a strong bactericidal action. Furthermore, in the case of taking out of the sealed container and culturing for 120 hours under the condition that the smoke gas is not filled, the colony appearance of ringworm fungi was maintained at 0% in the molded musk with bamboo powder. In the case of a commercially available molded musk, a colony appearance rate of 7% and growth of ringworm were observed. The result shows that the smoke gas of the molded scent has a bactericidal action against ringworm, which is stronger in the molded scent with bamboo powder.

  After placing 4 pieces of cone-shaped molded incense with bamboo powder prepared in Example 1-1 in a clog box (width 75 cm x height 150 cm x depth 30 cm, volume about 340 L) containing various footwear. It was burned completely in a flame-free state and filled with smoke gas. No foot ring fungus was detected from the footwear in the clog box after fumigation for 4 hours, and this method was an effective means for preventing the ringworm fungus infection.

Molded musk is used in the various rooms such as bathroom dressing room, pool changing room, martial arts storage, etc., because the smoke gas exhibits the bactericidal action of ringworm bacteria. Furthermore, ringworm bacteria adhering to various articles such as shoes, boots, slippers, sandals, sandals, socks, socks, socks, bath mats, martial arts jackets, armor, and shoe boxes can be sterilized. The method for killing ringworm of the present invention has remarkable utility.

Claims (3)

  A method for sterilizing ringworm fungi characterized by sterilization by exposure to smoke gas of molded musk.   The method for sterilizing ringworm fungus according to claim 1, wherein the molded musk contains bamboo powder. The method for sterilizing ringworm fungus according to claim 2, wherein the content of the bamboo powder is 25 mass% or more and 95 mass% or less of the molded musk.