CN106176336B - Poly hexamethylene biguanide disinfectant and the two-in-one gel manufacturing method of compound Chinese herb mosquito-fly repellent - Google Patents
Poly hexamethylene biguanide disinfectant and the two-in-one gel manufacturing method of compound Chinese herb mosquito-fly repellent Download PDFInfo
- Publication number
- CN106176336B CN106176336B CN201610532850.5A CN201610532850A CN106176336B CN 106176336 B CN106176336 B CN 106176336B CN 201610532850 A CN201610532850 A CN 201610532850A CN 106176336 B CN106176336 B CN 106176336B
- Authority
- CN
- China
- Prior art keywords
- parts
- hexamethylene biguanide
- poly hexamethylene
- disinfectant
- gel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/02—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/591—Mixtures of compounds not provided for by any of the codes A61K2800/592 - A61K2800/596
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention relates to disinfectants and repellant technical field, refer in particular to poly hexamethylene biguanide disinfectant and the two-in-one gel manufacturing method of compound Chinese herb mosquito-fly repellent, it includes that polyhexamethylene is 4-8 parts double, 10-15 parts of solvent, 15-25 parts of yellow wormwood artemisia cauline leaf, 15-25 parts of cinnamomum camphora branches and leaves, 15-25 parts of China tree branches and leaves, 15-25 parts of laurel branches and leaves, 5-15 parts of lavender cauline leaf, 15-25 parts of garlic, 15-25 parts of onion bulb, 15-25 parts of argy wormwood cauline leaf, 5-15 parts of pepper fruit, 15-25 parts of masson pine skin leaf, 15-25 parts of auxiliary agent, repellant performance is sterilized to stablize, sterilization and repellent effect good time are long, environmentally protective nontoxic safety and sanitation, not pathogenic not teratogenesis will not cancer, the advantages that without non-stimulated no allergy is permeated, manufacturing method is simple, it is easy.
Description
Technical field:
The present invention relates to disinfectants and repellant technical field, refer in particular to poly hexamethylene biguanide disinfectant and compound Chinese herb
The two-in-one gel manufacturing method of mosquito-fly repellent.
Background technique:
The sanitary insect pests such as repellent mosquitos and flies just have many methods from ancient so far.
Ancients are most common to drive mosquitos and flies with smog, and discovery can also drive mosquitos and flies etc. with pungent, stimulable type fragrance later.
Nineteen twenty-nine repefral is as chemical repellant artificial synthesized for the first time, for driving the insects such as mosquito.Second
During world war, the U.S. succeeds in developing Metadelphene (DEET), and hereafter, the preparation of artificial synthesized chemical repellant Chang Youxin goes out
It is existing.To currently, common chemical synthesis repellant has: Metadelphene, dihydropyrone, keeps away mosquito spirit, Ergol, interior first at dimethyl phthalate
Dimethyl phthalate etc..It is driven from the peppermint oil extracted in peppermint stem and leaf, the cycloheximide extracted in actinomycetes fermentation liquor etc., and well
Keep away agent.Current commodity repellant, typically compound preparation both at home and abroad, dosage form have liniment, plastics, spray etc., but
Function without disinfection and sterilization and prevention insect-borne transmission disease.As a kind of environmentally protective, nontoxic, safety and sanitation
Poly hexamethylene biguanide disinfectant, and the repellant extracted from a variety of medicinal plants and garlic onion food are used for human body skin
Skin disinfection and sterilization and the two-in-one gel preparation of mosquitos and flies is driven, had not been reported so far.Therefore, it develops a kind of environmentally protective nontoxic
The two-in-one gel of the repellants such as disinfectant and plant extraction liquid, it is concerned.
Summary of the invention:
The purpose of the present invention is in view of the deficiencies of the prior art, and provide poly hexamethylene biguanide disinfectant and compound medium-height grass
The two-in-one gel manufacturing method of medicine mosquito-fly repellent overcomes existing repellant not have disinfection and sterilization and prevention insect-borne transmission
The function of disease, providing a kind of is both disinfectant and the two-in-one gel manufacturing method of repellant, and disinfection repellant performance is steady
Fixed, sterilization and repellent effect good time are long, environmentally protective nontoxic safety and sanitation, not pathogenic not teratogenesis will not cancer, no infiltration
The advantages that non-stimulated no allergy, manufacturing method are simple, easy.
To achieve the above object, the present invention adopts the following technical scheme that, poly hexamethylene biguanide disinfectant and compound medium-height grass
The two-in-one gel of medicine mosquito-fly repellent includes following raw material by weight: polyhexamethylene is 4-8 parts double, 10-15 parts of solvent,
15-25 parts of yellow wormwood artemisia cauline leaf, 15-25 parts of cinnamomum camphora branches and leaves, 15-25 parts of China tree branches and leaves, 15-25 parts of laurel branches and leaves, lavender cauline leaf 5-
15 parts, 15-25 parts of garlic, 15-25 parts of onion bulb, 15-25 parts of argy wormwood cauline leaf, 5-15 parts of pepper fruit, masson pine skin leaf 15-25
Part, 15-25 parts of auxiliary agent.
The auxiliary agent includes following component by weight: Mint Essence 0.1-1 parts edible, edible lemon extract 0.1-
1 part, 0.1-1 parts of fresh food sesame oil, 1-15 parts of fresh food soybean oil, vitamin E and 1-8 parts of rich mixture.
Poly hexamethylene biguanide disinfectant and the two-in-one gel manufacturing method of compound Chinese herb mosquito-fly repellent, including it is as follows
Specific steps:
(1) disappear using environmentally protective, nontoxic, safety and sanitation 800mg/L poly hexamethylene biguanide and 71% are medical
Poisonous wine essence forms compound disinfectant.
(2) Chinese herbal medicine mosquito-fly repellent raw material are made of following medicinal plant parts by weight: 15-25 parts of yellow wormwood artemisia cauline leaf,
15-25 parts of cinnamomum camphora branches and leaves, 15-25 parts of China tree branches and leaves, 15-25 parts of laurel branches and leaves, 5-15 parts of lavender cauline leaf, garlic 15-25
Part, 15-25 parts of onion bulb, 15-25 parts of argy wormwood cauline leaf, 5-15 parts of pepper fruit, 15-25 parts of masson pine skin leaf, 15-25 parts of auxiliary agent.
(3) above-mentioned each medicinal plant parts by weight are weighed up, medicinal plant branch skin leaf is written into 1- with axe or chopper
Pepper corn is added in 2cm fritter, and mixing, after being crushed to 2-3mm with pulverizer, being fitted into 100kg has in lid PE plastic barrel, garlic ocean
Green onion is shredded with kitchen knife and is also placed in PE plastic barrel, with the above-mentioned each plant raw material of 95% medicinal alcohol sealed soak of concentration of 56.8L
10d is expected, to extract its effective ingredient；In 3-5 DEG C of temperature environment, with adding the anti-alcohol of outer cover to volatilize filter press, 500 mesh filters pressings
After filter, filtrate and filters pressing filter cake are obtained, filter cake is smashed to pieces, and deionized water 20L, then filters pressing are added, and filtrate merges twice, and filtrate finally spends
Ionized water is settled to 77.8L, filtrate alcohol concentration 73%.
(4) auxiliary agent is added in filtrate: auxiliary agent parts by weight are as follows: Mint Essence 0.1-1 parts edible, edible lemon extract
0.1-1 parts, 0.1-1 parts of fresh food sesame oil, 1-15 parts of fresh food soybean oil, vitamin E and 1-8 parts of rich mixture.
(5) 5-8 parts of carbomer weight ratio, after being sufficiently mixed, closed 7-8h under room temperature are added, allows it to be swollen, is subsequently to added into
8 parts of weight ratio poly hexamethylene biguanide, 1 part of polyethylene glycol-400, after being sufficiently mixed, are stirred on one side, and medical three second is added dropwise on one side
0.88 part of hydramine, until gel-forming, poly hexamethylene biguanide active constituent content 800mg/L in filtrate gel at this time,
Alcohol concentration is 71%, i.e., poly hexamethylene biguanide disinfectant is made completely with the two-in-one gel of compound Chinese herb mosquito-fly repellent
At.
(6) poly hexamethylene biguanide disinfectant and the two-in-one gel coating human skin of compound Chinese herb mosquito-fly repellent
Afterwards, alcohol and moisture vapor away quickly, the repellants effective component such as remaining poly hexamethylene biguanide and medicinal plant extract,
It will be retained in for a long time in soybean oil and sesame oil coating, have to disinfectant poly hexamethylene biguanide and mosquito-fly repellent Chinese herbal medicine
Effect ingredient plays effective slow releasing function.
The present invention has the effect of positive: poly hexamethylene biguanide disinfectant and compound Chinese herb mosquito-fly repellent are two-in-one
After gel coating human skin, alcohol and moisture vapor away quickly, the medicinal plant after remaining poly hexamethylene biguanide and extraction
Object repellant effective component is retained in the very thin coating of soybean oil, sesame oil, plays slow releasing function for disinfectant and repellant.
According to GB/T13917.9--2009 agriculture chemical registration hygienic insecticide indoor pharmacodynamic test and evaluation, Part IX,
Test method and evaluation specified in repellant: measure of merit is carried out to repellant, laboratory experiment shows right in laboratory
Aedes w-alba effective protecting time > 12h.Field test shows to effectively prevent people knob yellow-fever mosquito effective protecting time to reach
13h bites effective protecting time up to 13h to rice field area Anopheles sinensis.3, " the disinfection skill specified according to the 2002 Nian Ban Ministry of Public Health
Art specification " in 2.1.1 disinfectant germicidal experiment, this disinfection repellent gel sterilize logarithm it is as follows: Escherichia coli (8099)
> 5, Staphylococcus aureus (ATCC 6538) > 5, Candida albicans (ATCC 10321) >=4.
Stability test: 37 DEG C always, 90d, poly hexamethylene biguanide are continuously stored in relative humidity 75--80% environment
Effective component reduces 4.8%, and to aedes w-alba effective protecting time > 12h in laboratory, repellent effect has no reduction.In room temperature room
Keep sample preservation 2.5 years, to aedes w-alba effective protecting time still > 12h in laboratory；Sterilize logarithm: Escherichia coli (8099)
> 5, Staphylococcus aureus (ATCC 6538) > 5, Candida albicans (ATCC10321) >=4.According to GB/T5009.37-2003
4.1 acid value determinations in " analysis method of edible vegetable oil sanitary standard ", after two-in-one gel makes, acid value is 0.08 (KOH/
Mg/g), after room temperature keeps sample 2.5 years, acid value is still 0.08 (KOH/mg/g).It is sterilized because containing poly hexamethylene biguanide in gel
Agent, the fat hydrolase in soybean oil, sesame oil are inactivated, and all microorganisms can not survive, and have vitamin E antioxygen again in addition
The presence of agent, thus grease can not be rancid rotten in two-in-one gel, therefore this product shelf-life, it can be set to 2.5 years.
After sterilizing the two-in-one gelling agent coating human skin of repellant, alcohol and moisture vapor away quickly, and remaining poly- six
The insect repellant ingredients such as methylene biguanides and plant, are retained in soybean oil and sesame oil coating, play for disinfectant and repellant
Slow releasing function, therefore disinfection and the effect of repellent mosquitos and flies are extended, disinfection repellant performance is stablized, sterilization and repellent effect good time
It is long, the advantages that environmentally protective nontoxic safety and sanitation, not pathogenic, not teratogenesis, not carcinogenic, no infiltration non-stimulated no allergy, make
It is simple, easy to make method.
Specific embodiment:
Poly hexamethylene biguanide disinfectant of the present invention and the two-in-one gel of compound Chinese herb mosquito-fly repellent, by weight
Including following raw material: 4-8 parts of polyhexamethylene pair, 10-15 parts of solvent, yellow 15-25 parts of wormwood artemisia cauline leaf, 15-25 parts of cinnamomum camphora branches and leaves, hardship
15-25 parts of chinaberry branches and leaves, 15-25 parts of laurel branches and leaves, 5-15 parts of lavender cauline leaf, 15-25 parts of garlic, 15-25 parts of onion bulb, Chinese mugwort
15-25 parts of wormwood artemisia cauline leaf, 5-15 parts of pepper fruit, 15-25 parts of masson pine skin leaf, 15-25 parts of auxiliary agent.
The auxiliary agent includes following component by weight: Mint Essence 0.1-1 parts edible, edible lemon extract 0.1-
1 part, 0.1-1 parts of fresh food sesame oil, 1-15 parts of fresh food soybean oil, vitamin E and 1-8 parts of rich mixture.
Poly hexamethylene biguanide disinfectant and the two-in-one gel manufacturing method of compound Chinese herb mosquito-fly repellent, including it is as follows
Specific steps:
(1) disappear using environmentally protective, nontoxic, safety and sanitation 800mg/L poly hexamethylene biguanide and 71% are medical
Poisonous wine essence forms compound disinfectant.
(2) Chinese herbal medicine mosquito-fly repellent raw material are made of following medicinal plant parts by weight: 15-25 parts of yellow wormwood artemisia cauline leaf,
15-25 parts of cinnamomum camphora branches and leaves, 15-25 parts of China tree branches and leaves, 15-25 parts of laurel branches and leaves, 5-15 parts of lavender cauline leaf, garlic 15-25
Part, 15-25 parts of onion bulb, 15-25 parts of argy wormwood cauline leaf, 5-15 parts of pepper fruit, 15-25 parts of masson pine skin leaf, 15-25 parts of auxiliary agent.
(3) above-mentioned each medicinal plant parts by weight are weighed up, medicinal plant branch skin leaf is written into 1- with axe or chopper
2cm fritter is added pepper (grain), mixing, and after being crushed to 2-3mm with pulverizer, being fitted into 100kg has in lid PE plastic barrel, garlic
Onion is shredded with kitchen knife and is also placed in PE plastic barrel, former with the above-mentioned each plant of the 95% medicinal alcohol sealed soak of concentration of 56.8L
Material 10d, to extract its effective ingredient；In 3-5 DEG C of temperature environment, with adding the anti-alcohol of outer cover to volatilize filter press, 500 mesh filters pressings
After filtering, filtrate and filters pressing filter cake are obtained, filter cake is smashed to pieces, and deionized water 20L, then filters pressing are added, and filtrate merges twice, and filtrate is finally used
Deionized water is settled to 77.8L, filtrate alcohol concentration 73%.
(4) auxiliary agent is added in filtrate: auxiliary agent parts by weight are as follows: Mint Essence 0.1-1 parts edible, edible lemon extract
0.1-1 parts, 0.1-1 parts of fresh food sesame oil, 1-15 parts of fresh food soybean oil, vitamin E and 1-8 parts of rich mixture.
(5) 5-8 parts of carbomer weight ratio, after being sufficiently mixed, closed 7-8h under room temperature are added, allows it to be swollen, is subsequently to added into
8 parts of weight ratio poly hexamethylene biguanide, 1 part of polyethylene glycol-400, after being sufficiently mixed, are stirred on one side, and medical three second is added dropwise on one side
0.88 part of hydramine, until gel-forming, poly hexamethylene biguanide active constituent content 800mg/L in filtrate gel at this time,
Alcohol concentration is 71%, i.e., poly hexamethylene biguanide disinfectant is made completely with the two-in-one gel of compound Chinese herb mosquito-fly repellent
At.
(6) poly hexamethylene biguanide disinfectant and the two-in-one gel coating human skin of compound Chinese herb mosquito-fly repellent
Afterwards, alcohol and moisture vapor away quickly, the repellants effective component such as remaining poly hexamethylene biguanide and medicinal plant extract,
It will be retained in for a long time in soybean oil and sesame oil coating, have to disinfectant poly hexamethylene biguanide and mosquito-fly repellent Chinese herbal medicine
Effect ingredient plays effective slow releasing function.
After poly hexamethylene biguanide disinfectant and the two-in-one gel coating human skin of compound Chinese herb mosquito-fly repellent, wine
Essence and moisture vapor away quickly, and the medicinal plant repellant effective component after remaining poly hexamethylene biguanide and extraction retains
In soybean oil, the very thin coating of sesame oil, slow releasing function is played for disinfectant and repellant.
According to GB/T13917.9--2009 agriculture chemical registration hygienic insecticide indoor pharmacodynamic test and evaluation, Part IX,
Test method and evaluation specified in repellant: measure of merit is carried out to repellant, laboratory experiment shows right in laboratory
Aedes w-alba effective protecting time > 12h.Field test shows to effectively prevent people knob yellow-fever mosquito effective protecting time to reach
13h bites effective protecting time up to 13h to rice field area Anopheles sinensis.
2.1.1 disinfectant germicidal experiment in " disinfection technology standard " specified according to the 2002 Nian Ban Ministry of Public Health, originally disappears
Malicious repellent gel sterilization logarithm is as follows: Escherichia coli (8099) > 5, Staphylococcus aureus (ATCC 6538) > 5, white are read
Pearl bacterium (ATCC 10321) >=4.
Stability test: 37 DEG C always, 90d, poly hexamethylene biguanide are continuously stored in relative humidity 75--80% environment
Effective component reduces 4.8%, and to aedes w-alba effective protecting time > 12h in laboratory, repellent effect has no reduction.In room temperature room
Keep sample preservation 2.5 years, to aedes w-alba effective protecting time still > 12h in laboratory；Sterilize logarithm: Escherichia coli (8099)
> 5, Staphylococcus aureus (ATCC 6538) > 5, Candida albicans (ATCC 10321) >=4.According to GB/T5009.37-2003
4.1 acid value determinations in " analysis method of edible vegetable oil sanitary standard ", after two-in-one gel makes, acid value is 0.08 (KOH/
Mg/g), after room temperature keeps sample 2.5 years, acid value is still 0.08 (KOH/mg/g).It is sterilized because containing poly hexamethylene biguanide in gel
Agent, the fat hydrolase in soybean oil, sesame oil are inactivated, and all microorganisms can not survive, and have vitamin E antioxygen again in addition
The presence of agent, thus grease can not be rancid rotten in two-in-one gel.Therefore this product shelf-life, it can be set to 2.5 years.
Toxicity test: mouse oral toxicity test is practical nontoxic as a result, LD50 > 5000mg/L weight；Chmice acute
Toxicity on inhalation test result, LC500 2h > 10000mg/m3 are practical nontoxic.
Mice bone marrow micronucleus is feminine gender, i.e., without mutagenicity.
Skin Irritation Test: to rabbit skin irritation test as a result, non-stimulated.
Guinea pig skin allergy is tested, sensitization rate is 0%, that is, has no skin allergic reaction.
After sterilizing the two-in-one gelling agent coating human skin of repellant, alcohol and moisture vapor away quickly, and remaining poly- six
The insect repellant ingredients such as methylene biguanides and plant, are retained in soybean oil and sesame oil coating, play for disinfectant and repellant
Slow releasing function, therefore disinfection and the effect of repellent mosquitos and flies are extended, disinfection repellant performance is stablized, sterilization and repellent effect good time
It is long, environmentally protective nontoxic safety and sanitation, not pathogenic not teratogenesis will not cancer, the advantages that no infiltration non-stimulated no allergy, manufacture
Method is simple, easy.
The above is only presently preferred embodiments of the present invention, thus it is all according to the configuration described in the scope of the patent application of the present invention, it is special
The equivalent change or modification that sign and principle are done, is included in the scope of the patent application of the present invention.
Claims (3)
1. poly hexamethylene biguanide disinfectant and the two-in-one gel of compound Chinese herb mosquito-fly repellent, it is characterised in that: by weight
Part meter includes following raw material: 4-8 parts of poly hexamethylene biguanide disinfectant, 10-15 parts of solvent, yellow 15-25 parts of wormwood artemisia cauline leaf, cinnamomum camphora branch
15-25 parts of leaf, 15-25 parts of China tree branches and leaves, 15-25 parts of laurel branches and leaves, 5-15 parts of lavender cauline leaf, 15-25 parts of garlic, onion
Head 15-25 parts, 15-25 parts of argy wormwood cauline leaf, 5-15 parts of pepper fruit, 15-25 parts of masson pine skin leaf, 15-25 parts of auxiliary agent.
2. poly hexamethylene biguanide disinfectant according to claim 1 and compound Chinese herb mosquito-fly repellent are two-in-one solidifying
Glue, it is characterised in that: the auxiliary agent includes following component by weight: Mint Essence 0.1-1 parts edible, edible lemonene
It is 0.1-1 parts smart, 0.1-1 parts of fresh food sesame oil, 1-15 parts of fresh food soybean oil, vitamin E and rich mixture 1-8
Part.
3. poly hexamethylene biguanide disinfectant according to claim 1 and the two-in-one gel of compound Chinese herb mosquito-fly repellent
Manufacturing method comprises the following specific steps that:
(1) environmentally protective, nontoxic, safety and sanitation 800mg/L poly hexamethylene biguanide and 71% medical disinfecting wine are used
Essence composition compound disinfectant；
(2) Chinese herbal medicine mosquito-fly repellent raw material are made of following medicinal plant parts by weight: 15-25 parts of yellow wormwood artemisia cauline leaf, cinnamomum camphora
15-25 parts of branches and leaves, 15-25 parts of China tree branches and leaves, 15-25 parts of laurel branches and leaves, 5-15 parts of lavender cauline leaf, 15-25 parts of garlic, ocean
15-25 parts of onion, 15-25 parts of argy wormwood cauline leaf, 5-15 parts of pepper fruit, 15-25 parts of masson pine skin leaf, 15-25 parts of auxiliary agent；
(3) above-mentioned each medicinal plant parts by weight are weighed up, it is small to be written into 1-2cm with axe or chopper for medicinal plant branch skin leaf
Pepper fruit is added in block, and mixing, after being crushed to 2-3mm with pulverizer, being fitted into 100kg has in lid PE plastic barrel, garlic onion dish
Knife chopping is also placed in PE plastic barrel, with the above-mentioned each material of vegetable origin 10d of 95% medicinal alcohol sealed soak of concentration of 56.8L,
To extract its effective ingredient；In 3-5 DEG C of temperature environment, with adding the anti-alcohol of outer cover to volatilize filter press, after 500 mesh filters pressings filtering,
It obtains filtrate and filters pressing filter cake, filter cake is smashed to pieces, add deionized water 20L, then filters pressing, filtrate merges twice, and filtrate finally uses deionization
Water is settled to 77.8L, filtrate alcohol concentration 73%；
(4) auxiliary agent is added in filtrate: auxiliary agent parts by weight are as follows: Mint Essence 0.1-1 parts edible, edible lemon extract 0.1-1
Part, 0.1-1 parts of fresh food sesame oil, 1-15 parts of fresh food soybean oil, vitamin E and 1-8 parts of rich mixture；
(5) 5-8 parts of carbomer weight ratio, after being sufficiently mixed, closed 7-8h under room temperature are added, allows it to be swollen, is subsequently to added into weight
Than 8 parts of poly hexamethylene biguanide, 1 part of polyethylene glycol-400, after being sufficiently mixed, stirs on one side, medical triethanolamine is added dropwise on one side
0.88 part, until gel-forming, poly hexamethylene biguanide active constituent content 800mg/L, alcohol in filtrate gel at this time
Concentration is 71%, i.e., poly hexamethylene biguanide disinfectant is completely formed with the two-in-one gel of compound Chinese herb mosquito-fly repellent；
(6) after poly hexamethylene biguanide disinfectant and the two-in-one gel coating human skin of compound Chinese herb mosquito-fly repellent, wine
Essence and moisture vapor away quickly, and the repellants effective component such as remaining poly hexamethylene biguanide and medicinal plant extract will be grown
Time is retained in soybean oil and sesame oil coating, to disinfectant poly hexamethylene biguanide and mosquito-fly repellent Chinese herbal medicine effectively at
Divide and plays effective slow releasing function.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610532850.5A CN106176336B (en) | 2016-07-07 | 2016-07-07 | Poly hexamethylene biguanide disinfectant and the two-in-one gel manufacturing method of compound Chinese herb mosquito-fly repellent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610532850.5A CN106176336B (en) | 2016-07-07 | 2016-07-07 | Poly hexamethylene biguanide disinfectant and the two-in-one gel manufacturing method of compound Chinese herb mosquito-fly repellent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106176336A CN106176336A (en) | 2016-12-07 |
| CN106176336B true CN106176336B (en) | 2019-03-19 |
Family
ID=57472444
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610532850.5A Active CN106176336B (en) | 2016-07-07 | 2016-07-07 | Poly hexamethylene biguanide disinfectant and the two-in-one gel manufacturing method of compound Chinese herb mosquito-fly repellent |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106176336B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108186411A (en) * | 2018-02-28 | 2018-06-22 | 张立波 | A kind of plants essential oil with antibacterial functions drives, keeps away mosquito liquid and preparation method thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1478397A (en) * | 2003-07-03 | 2004-03-03 | 惠州兆婷化妆品有限公司 | Formulatioin of disinfecting liquid |
| CN1709398A (en) * | 2005-06-06 | 2005-12-21 | 沈阳药科大学 | Filtering-degerming Chinese medicine or animal-plant volatile oil or fat emulsion and preparing method |
| CN101186772A (en) * | 2007-12-04 | 2008-05-28 | 华南农业大学 | Helminthic emulsion paint and preparation method thereof |
| CN102949749A (en) * | 2012-11-28 | 2013-03-06 | 金红叶纸业集团有限公司 | Disposable absorbent product |
| CN103627126A (en) * | 2012-08-20 | 2014-03-12 | 叶向明 | Antibiosis master batch and application of antibiosis master batch in blended yarn, blended fabric and woven fabric |
| CN104499071A (en) * | 2014-12-22 | 2015-04-08 | 青岛大统纺织开发有限公司 | Traditional Chinese medicine anthelmintic auxiliary agent and application thereof |
-
2016
- 2016-07-07 CN CN201610532850.5A patent/CN106176336B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1478397A (en) * | 2003-07-03 | 2004-03-03 | 惠州兆婷化妆品有限公司 | Formulatioin of disinfecting liquid |
| CN1709398A (en) * | 2005-06-06 | 2005-12-21 | 沈阳药科大学 | Filtering-degerming Chinese medicine or animal-plant volatile oil or fat emulsion and preparing method |
| CN101186772A (en) * | 2007-12-04 | 2008-05-28 | 华南农业大学 | Helminthic emulsion paint and preparation method thereof |
| CN103627126A (en) * | 2012-08-20 | 2014-03-12 | 叶向明 | Antibiosis master batch and application of antibiosis master batch in blended yarn, blended fabric and woven fabric |
| CN102949749A (en) * | 2012-11-28 | 2013-03-06 | 金红叶纸业集团有限公司 | Disposable absorbent product |
| CN104499071A (en) * | 2014-12-22 | 2015-04-08 | 青岛大统纺织开发有限公司 | Traditional Chinese medicine anthelmintic auxiliary agent and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106176336A (en) | 2016-12-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR100285781B1 (en) | Essential oil composition with antibacterial and antifungal action | |
| KR101075779B1 (en) | Antimicrobial and deodorant composition containing herbal extract | |
| CN105831183A (en) | Composite plant source pesticide and preparation method | |
| KR101423374B1 (en) | Process for producing livestock deodorant including herb extracts | |
| Alhassan et al. | Phytochemical analysis, proximate composition and antibacterial activities of Ziziphus species (Z. jujube and Z. spina-christi) | |
| CN107873701A (en) | A kind of aerosol for expelling parasite, sterilizing and mite killing and preparation method thereof | |
| CN110063329A (en) | It is a kind of to meet organic agriculture and inhibited and natural plants oil assistant and preparation method thereof of synergy, application using having both plant disease | |
| CN106417289A (en) | Pesticide for preventing and controlling litchi whiteflies and preparation method thereof | |
| KR102205206B1 (en) | Antibacterial deodorization composition comprising EM fermentation metabolites and cannabis extracts and composition method thereof | |
| US20060153890A1 (en) | Insect repellent | |
| CN106176336B (en) | Poly hexamethylene biguanide disinfectant and the two-in-one gel manufacturing method of compound Chinese herb mosquito-fly repellent | |
| Mouna et al. | Insecticidal effect of two aqueous extracts from the leaves of Salvia officinalis and Eucalyptus camaldulensis against Aphis fabae | |
| CN105638790A (en) | Deodorizing mosquito repellent and preparation method thereof | |
| KR102206192B1 (en) | Method for manufacturing eco-friendly pest repellent for horticulture and eco-friendly pest repellent for horticulture manufactured thereby | |
| KR101477078B1 (en) | Natural deodorant and germicide comprising crude drugs and manufacturaring process for the same | |
| CN109392956A (en) | Plant mosquitofugal oil | |
| KR100785427B1 (en) | fragnance emitter to shoo insect provided by element of natural herb | |
| KR102558841B1 (en) | Eco-friendly control agent for weeds and methods for manufacturing the same | |
| JP2011105757A (en) | Japanese plum extract | |
| KR102555866B1 (en) | Manufacturing method of sterilizing and deodorant composition using natural material | |
| JP4756262B2 (en) | Deodorant antibacterial preservative and method | |
| JP2011105757A5 (en) | ||
| Sekar et al. | Formulation and evaluation of Novel and natural mosquito repellent liquid to prevent dengue mosquitoes | |
| CN106804631A (en) | A kind of preparation method of plant source domestic pesticide | |
| CN106332918A (en) | Pesticide for preventing olethreutes leucaspis meyrick in litchi and preparing method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |