JP2006528147A5 - - Google Patents
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- Publication number
- JP2006528147A5 JP2006528147A5 JP2006520762A JP2006520762A JP2006528147A5 JP 2006528147 A5 JP2006528147 A5 JP 2006528147A5 JP 2006520762 A JP2006520762 A JP 2006520762A JP 2006520762 A JP2006520762 A JP 2006520762A JP 2006528147 A5 JP2006528147 A5 JP 2006528147A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- formula
- group
- compound
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0316893A GB0316893D0 (en) | 2003-07-18 | 2003-07-18 | Novel compounds |
| GB0411167A GB0411167D0 (en) | 2004-05-19 | 2004-05-19 | Novel compounds |
| PCT/EP2004/008061 WO2005014571A1 (en) | 2003-07-18 | 2004-07-16 | Substituted piperidines as histamine h3 receptor ligands |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006528147A JP2006528147A (ja) | 2006-12-14 |
| JP2006528147A5 true JP2006528147A5 (OSRAM) | 2007-07-19 |
Family
ID=34137741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006520762A Pending JP2006528147A (ja) | 2003-07-18 | 2004-07-16 | ヒスタミンｈ３受容体リガンドとしての置換ピペリジン |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20060247227A1 (OSRAM) |
| EP (1) | EP1646620B1 (OSRAM) |
| JP (1) | JP2006528147A (OSRAM) |
| AR (1) | AR045999A1 (OSRAM) |
| AT (1) | ATE370135T1 (OSRAM) |
| DE (1) | DE602004008291T2 (OSRAM) |
| ES (1) | ES2291913T3 (OSRAM) |
| TW (1) | TW200514781A (OSRAM) |
| WO (1) | WO2005014571A1 (OSRAM) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007010350A1 (en) * | 2005-07-19 | 2007-01-25 | Pfizer Products Inc. | Synthesis of therapeutic diphenyl ethers |
| WO2007016496A2 (en) | 2005-08-02 | 2007-02-08 | Neurogen Corporation | Dipiperazinyl ketones and related analogues |
| CA2687931C (en) | 2007-05-31 | 2016-05-24 | Boehringer Ingelheim International Gmbh | Ccr2 receptor antagonists and uses thereof |
| CA2700963A1 (en) * | 2007-09-28 | 2009-04-09 | Schering Corporation | Oxypiperidine derivatives and methods of use thereof |
| EA020548B1 (ru) | 2008-12-19 | 2014-12-30 | Бёрингер Ингельхайм Интернациональ Гмбх | Циклические пиримидин-4-карбоксамиды в качестве антагонистов рецептора ccr2, предназначенные для лечения воспаления, астмы и хозл |
| ME01908B (me) | 2009-12-17 | 2014-12-20 | Boehringer Ingelheim Int | Novi antagonisti ccr2 receptora i njihova primjena |
| WO2011141477A1 (en) | 2010-05-12 | 2011-11-17 | Boehringer Ingelheim International Gmbh | New ccr2 receptor antagonists, method for producing the same, and use thereof as medicaments |
| US8877745B2 (en) | 2010-05-12 | 2014-11-04 | Boehringer Ingelheim International Gmbh | CCR2 receptor antagonists, method for producing the same, and use thereof as medicaments |
| US8841313B2 (en) | 2010-05-17 | 2014-09-23 | Boehringer Ingelheim International Gmbh | CCR2 antagonists and uses thereof |
| CN102260277B (zh) | 2010-05-24 | 2013-07-24 | 中国科学院上海药物研究所 | 新型苯并噁嗪噁唑烷酮类化合物及其制备方法和用途 |
| WO2011147772A1 (en) | 2010-05-25 | 2011-12-01 | Boehringer Ingelheim International Gmbh | Ccr2 receptor antagonists |
| EP2576538B1 (en) | 2010-06-01 | 2015-10-28 | Boehringer Ingelheim International GmbH | New CCR2 antagonists |
| ES2823350T3 (es) | 2010-07-29 | 2021-05-06 | Rigel Pharmaceuticals Inc | Compuestos heterocíclicos que activan AMPK y métodos de uso de los mismos |
| EP2731941B1 (en) | 2011-07-15 | 2019-05-08 | Boehringer Ingelheim International GmbH | Novel and selective ccr2 antagonists |
| AU2013211417A1 (en) * | 2012-01-16 | 2014-07-31 | Glaxosmithkline Intellectual Property Development Limited | Therapeutic uses |
| CN104114538B (zh) * | 2012-01-16 | 2016-04-13 | 葛兰素史克知识产权发展有限公司 | 治疗用途 |
| WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
| EP2647377A1 (en) | 2012-04-06 | 2013-10-09 | Sanofi | Use of an h3 receptor antagonist for the treatment of alzheimer's disease |
| AU2016287584B2 (en) | 2015-07-02 | 2020-03-26 | Centrexion Therapeutics Corporation | (4-((3R,4R)-3-methoxytetrahydro-pyran-4-ylamino)piperidin-1-yl)(5-methyl-6-(((2R,6S)-6-(p-tolyl)tetrahydro-2H-pyran-2-yl)methylamino)pyrimidin-4yl)methanone citrate |
| EP3383853B1 (en) * | 2015-12-01 | 2020-11-04 | Merck Sharp & Dohme Corp. | Homobispiperidinyl derivatives as liver x receptor (lxr) beta agonists for treating e.g. alzheimer's disease |
| JP2025511097A (ja) * | 2022-03-31 | 2025-04-15 | 廣州必貝特醫藥股▲ふん▼有限公司 | １，４－ジヘテロシクリル置換芳香環若しくは芳香族複素環系化合物及びその使用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20020507A1 (es) * | 2000-10-17 | 2002-06-25 | Schering Corp | Compuestos no-imidazoles como antagonistas del receptor histamina h3 |
| CA2436083A1 (en) * | 2001-02-08 | 2002-09-19 | Schering Corporation | Use of dual h3/m2 antagonists in the treatment of cognition deficit disorders |
| WO2003031432A1 (en) * | 2001-10-12 | 2003-04-17 | Novo Nordisk A/S | Substituted piperidines and their use for the treatment of diseases related to the histamine h3 receptor |
| AU2003242252A1 (en) * | 2002-06-07 | 2003-12-22 | Kyowa Hakko Kogyo Co., Ltd. | Bicyclic pyrimidine derivatives |
-
2004
- 2004-07-16 AR ARP040102526A patent/AR045999A1/es unknown
- 2004-07-16 WO PCT/EP2004/008061 patent/WO2005014571A1/en not_active Ceased
- 2004-07-16 US US10/564,931 patent/US20060247227A1/en not_active Abandoned
- 2004-07-16 DE DE602004008291T patent/DE602004008291T2/de not_active Expired - Fee Related
- 2004-07-16 AT AT04763339T patent/ATE370135T1/de not_active IP Right Cessation
- 2004-07-16 TW TW093121228A patent/TW200514781A/zh unknown
- 2004-07-16 JP JP2006520762A patent/JP2006528147A/ja active Pending
- 2004-07-16 EP EP04763339A patent/EP1646620B1/en not_active Expired - Lifetime
- 2004-07-16 ES ES04763339T patent/ES2291913T3/es not_active Expired - Lifetime
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