JP2006527380A5 - - Google Patents
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- JP2006527380A5 JP2006527380A5 JP2006516796A JP2006516796A JP2006527380A5 JP 2006527380 A5 JP2006527380 A5 JP 2006527380A5 JP 2006516796 A JP2006516796 A JP 2006516796A JP 2006516796 A JP2006516796 A JP 2006516796A JP 2006527380 A5 JP2006527380 A5 JP 2006527380A5
- Authority
- JP
- Japan
- Prior art keywords
- electrode
- surface substrate
- cell
- substrate according
- gate electrode
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000758 substrate Substances 0.000 claims 11
- 210000004027 cell Anatomy 0.000 claims 7
- 230000001737 promoting effect Effects 0.000 claims 4
- 102400001107 Secretory component Human genes 0.000 claims 2
- 210000000170 cell membrane Anatomy 0.000 claims 2
- 229910021420 polycrystalline silicon Inorganic materials 0.000 claims 2
- 229920005591 polysilicon Polymers 0.000 claims 2
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 claims 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 claims 1
- 230000015556 catabolic process Effects 0.000 claims 1
- 230000021164 cell adhesion Effects 0.000 claims 1
- 230000023402 cell communication Effects 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 210000000078 claw Anatomy 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 238000006731 degradation reaction Methods 0.000 claims 1
- 238000005530 etching Methods 0.000 claims 1
- 210000002744 extracellular matrix Anatomy 0.000 claims 1
- 150000002500 ions Chemical class 0.000 claims 1
- 238000001459 lithography Methods 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47703703P | 2003-06-10 | 2003-06-10 | |
| US60/477,037 | 2003-06-10 | ||
| PCT/IL2004/000502 WO2004109282A1 (en) | 2003-06-10 | 2004-06-10 | Electronic device for communication with living cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006527380A JP2006527380A (ja) | 2006-11-30 |
| JP2006527380A5 true JP2006527380A5 (enExample) | 2007-05-10 |
| JP4728956B2 JP4728956B2 (ja) | 2011-07-20 |
Family
ID=33511831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006516796A Expired - Lifetime JP4728956B2 (ja) | 2003-06-10 | 2004-06-10 | 生体細胞との通信のための電子装置 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US7795039B2 (enExample) |
| EP (1) | EP1634075B1 (enExample) |
| JP (1) | JP4728956B2 (enExample) |
| WO (1) | WO2004109282A1 (enExample) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4728956B2 (ja) | 2003-06-10 | 2011-07-20 | イサム リサーチ デベロップメント カンパニー オブ ザ ヘブルー ユニバーシティ オブ エルサレム | 生体細胞との通信のための電子装置 |
| GB0322010D0 (en) * | 2003-09-19 | 2003-10-22 | Univ Cambridge Tech | Detection of molecular interactions using field effect transistors |
| US20090299213A1 (en) * | 2006-03-15 | 2009-12-03 | President And Fellows Of Harvard College | Nanobioelectronics |
| DE602007012248D1 (de) | 2006-06-12 | 2011-03-10 | Harvard College | Nanosensoren und entsprechende technologien |
| WO2008021758A1 (en) * | 2006-08-11 | 2008-02-21 | Home Diagnostics, Inc. | Methods for fabricating a biosensor with a surface texture |
| EP2095100B1 (en) | 2006-11-22 | 2016-09-21 | President and Fellows of Harvard College | Method of operating a nanowire field effect transistor sensor |
| AU2007334393A1 (en) | 2006-12-14 | 2008-06-26 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| US8349167B2 (en) | 2006-12-14 | 2013-01-08 | Life Technologies Corporation | Methods and apparatus for detecting molecular interactions using FET arrays |
| US11339430B2 (en) | 2007-07-10 | 2022-05-24 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| US8262900B2 (en) | 2006-12-14 | 2012-09-11 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| WO2008111047A1 (en) * | 2007-03-09 | 2008-09-18 | Imec Vzw | Micro-nails for use in electrical interaction with cells |
| WO2009009185A2 (en) * | 2007-05-09 | 2009-01-15 | Massachusetts Institute Of Technology | Tunable surfaces |
| WO2010025547A1 (en) * | 2008-09-02 | 2010-03-11 | The Governing Council Of The University Of Toronto | Nanostructured microelectrodes and biosensing devices incorporating the same |
| US20100137143A1 (en) | 2008-10-22 | 2010-06-03 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes |
| US20100301398A1 (en) | 2009-05-29 | 2010-12-02 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes |
| WO2010121130A2 (en) | 2009-04-16 | 2010-10-21 | President And Fellows Of Harvard College | Molecular delivery with nanowires |
| US8776573B2 (en) | 2009-05-29 | 2014-07-15 | Life Technologies Corporation | Methods and apparatus for measuring analytes |
| US20120261274A1 (en) | 2009-05-29 | 2012-10-18 | Life Technologies Corporation | Methods and apparatus for measuring analytes |
| WO2011038228A1 (en) | 2009-09-24 | 2011-03-31 | President And Fellows Of Harvard College | Bent nanowires and related probing of species |
| AU2011226767B1 (en) | 2010-06-30 | 2011-11-10 | Life Technologies Corporation | Ion-sensing charge-accumulation circuits and methods |
| CN103080739B (zh) | 2010-06-30 | 2016-12-21 | 生命科技公司 | 用于测试isfet阵列的方法和装置 |
| US8487790B2 (en) | 2010-06-30 | 2013-07-16 | Life Technologies Corporation | Chemical detection circuit including a serializer circuit |
| US11307166B2 (en) | 2010-07-01 | 2022-04-19 | Life Technologies Corporation | Column ADC |
| TWI527245B (zh) | 2010-07-03 | 2016-03-21 | 生命技術公司 | 具有微摻雜汲極之化學感測器 |
| EP2617061B1 (en) | 2010-09-15 | 2021-06-30 | Life Technologies Corporation | Methods and apparatus for measuring analytes |
| US8685324B2 (en) | 2010-09-24 | 2014-04-01 | Life Technologies Corporation | Matched pair transistor circuits |
| US9629995B2 (en) | 2011-05-26 | 2017-04-25 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Biomolecular electronic device and process of use |
| WO2012170630A2 (en) | 2011-06-10 | 2012-12-13 | President And Fellows Of Harvard College | Nanoscale wires, nanoscale wire fet devices, and nanotube-electronic hybrid devices for sensing and other applications |
| WO2013024386A2 (en) * | 2011-08-16 | 2013-02-21 | 0Ec Sa | System for a contactless control of a field effect transistor |
| KR101366391B1 (ko) * | 2011-10-05 | 2014-02-25 | 한양대학교 산학협력단 | 세포 계수용 칩 |
| US9970984B2 (en) | 2011-12-01 | 2018-05-15 | Life Technologies Corporation | Method and apparatus for identifying defects in a chemical sensor array |
| US8786331B2 (en) | 2012-05-29 | 2014-07-22 | Life Technologies Corporation | System for reducing noise in a chemical sensor array |
| US9080968B2 (en) | 2013-01-04 | 2015-07-14 | Life Technologies Corporation | Methods and systems for point of use removal of sacrificial material |
| US9841398B2 (en) | 2013-01-08 | 2017-12-12 | Life Technologies Corporation | Methods for manufacturing well structures for low-noise chemical sensors |
| US8963216B2 (en) | 2013-03-13 | 2015-02-24 | Life Technologies Corporation | Chemical sensor with sidewall spacer sensor surface |
| US9835585B2 (en) | 2013-03-15 | 2017-12-05 | Life Technologies Corporation | Chemical sensor with protruded sensor surface |
| CN105264366B (zh) | 2013-03-15 | 2019-04-16 | 生命科技公司 | 具有一致传感器表面区域的化学传感器 |
| WO2014149779A1 (en) | 2013-03-15 | 2014-09-25 | Life Technologies Corporation | Chemical device with thin conductive element |
| US20140336063A1 (en) | 2013-05-09 | 2014-11-13 | Life Technologies Corporation | Windowed Sequencing |
| US10458942B2 (en) | 2013-06-10 | 2019-10-29 | Life Technologies Corporation | Chemical sensor array having multiple sensors per well |
| TWI647842B (zh) * | 2013-08-22 | 2019-01-11 | 美商生命技術公司 | 具薄導電元件之化學裝置 |
| KR20170097712A (ko) | 2014-12-18 | 2017-08-28 | 라이프 테크놀로지스 코포레이션 | 대형 fet 어레이를 사용한 분석물 측정을 위한 방법과 장치 |
| US10077472B2 (en) | 2014-12-18 | 2018-09-18 | Life Technologies Corporation | High data rate integrated circuit with power management |
| EP4354131A3 (en) | 2014-12-18 | 2024-06-26 | Life Technologies Corporation | High data rate integrated circuit with transmitter configuration |
| WO2016112315A2 (en) | 2015-01-09 | 2016-07-14 | President And Fellows Of Harvard College | Nanowire arrays for neurotechnology and other applications |
| GB201512600D0 (en) * | 2015-07-17 | 2015-08-26 | Koniku Ltd | Cell culture, transport and investigation |
| US11474103B2 (en) | 2017-02-17 | 2022-10-18 | Koniku Inc. | Systems for detection |
| CN107085097B (zh) * | 2017-05-14 | 2020-08-28 | 浙江达普生物科技有限公司 | 一种血检芯片及其制作方法 |
| KR20250125660A (ko) * | 2024-02-15 | 2025-08-22 | 서울대학교산학협력단 | 수직 나노구조체가 적용된 전계 효과 트랜지스터를 포함하는 세포 신호 측정 소자와 그 제조 및 동작 방법 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4546083A (en) * | 1983-04-22 | 1985-10-08 | Stolle Research & Development Corporation | Method and device for cell culture growth |
| US6846654B1 (en) * | 1983-11-29 | 2005-01-25 | Igen International, Inc. | Catalytic antibodies as chemical sensors |
| AU6353294A (en) * | 1993-03-01 | 1994-09-26 | Glycan Pharmaceuticals, Inc. | Analogs for specific oligosaccharide-protein interactions and uses therefor |
| DE19841337C1 (de) | 1998-05-27 | 1999-09-23 | Micronas Intermetall Gmbh | Verfahren und Vorrichtung zur intrazellulären Manipulation einer biologischen Zelle |
| JP3515908B2 (ja) * | 1998-09-24 | 2004-04-05 | エヌ・ティ・ティ・アドバンステクノロジ株式会社 | 微少量オンラインバイオセンサー及びその製造方法 |
| WO2000051191A1 (en) * | 1999-02-22 | 2000-08-31 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | A hybrid electrical device with biological components |
| JP2001156398A (ja) * | 1999-05-19 | 2001-06-08 | Canon Inc | 半導体素子の製造方法、半導体素子、及びジャイロ |
| NZ518057A (en) | 1999-10-01 | 2004-01-30 | Sophion Bioscience As | A substrate and a method for determining and/or monitoring electrophysiological properties of ion channels |
| IL153545A0 (en) | 2000-07-07 | 2003-07-06 | Bristol Myers Squibb Co | Apparatus for measuring cellular electrical activity |
| US6465331B1 (en) * | 2000-08-31 | 2002-10-15 | Micron Technology, Inc. | DRAM fabricated on a silicon-on-insulator (SOI) substrate having bi-level digit lines |
| US6914279B2 (en) | 2002-06-06 | 2005-07-05 | Rutgers, The State University Of New Jersey | Multifunctional biosensor based on ZnO nanostructures |
| IL152746A0 (en) | 2002-11-11 | 2003-06-24 | Yissum Res Dev Co | Biosensor for molecules |
| JP4728956B2 (ja) | 2003-06-10 | 2011-07-20 | イサム リサーチ デベロップメント カンパニー オブ ザ ヘブルー ユニバーシティ オブ エルサレム | 生体細胞との通信のための電子装置 |
| US7270973B2 (en) * | 2003-12-23 | 2007-09-18 | The United States Of America As Represented By The Secretary Of The Navy | Catalytic enzyme-modified textiles for active protection from toxins |
-
2004
- 2004-06-10 JP JP2006516796A patent/JP4728956B2/ja not_active Expired - Lifetime
- 2004-06-10 US US10/560,315 patent/US7795039B2/en not_active Expired - Fee Related
- 2004-06-10 WO PCT/IL2004/000502 patent/WO2004109282A1/en not_active Ceased
- 2004-06-10 EP EP04736573.9A patent/EP1634075B1/en not_active Expired - Lifetime
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