JP2006527232A - グルタミナーゼ及び抗新生物性のアントラサイクリン類又は白金化合物を含有する癌治療のための薬剤学的な組合せ製剤 - Google Patents
グルタミナーゼ及び抗新生物性のアントラサイクリン類又は白金化合物を含有する癌治療のための薬剤学的な組合せ製剤 Download PDFInfo
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/50—Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- Life Sciences & Earth Sciences (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| DE10326821A DE10326821A1 (de) | 2003-06-11 | 2003-06-11 | Pharmazeutische Kombinationspräparate zur Krebstherapie |
| PCT/EP2004/006320 WO2004108153A1 (de) | 2003-06-11 | 2004-06-11 | Pharmazeutische kombinationspräparate zur krebstherapie enthaltend glutaminase und antineoplastische anthracycline oder platinverbindungen |
Publications (2)
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| JP2006527232A true JP2006527232A (ja) | 2006-11-30 |
| JP2006527232A5 JP2006527232A5 (enExample) | 2007-06-21 |
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| JP2006515900A Pending JP2006527232A (ja) | 2003-06-11 | 2004-06-11 | グルタミナーゼ及び抗新生物性のアントラサイクリン類又は白金化合物を含有する癌治療のための薬剤学的な組合せ製剤 |
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| CA (1) | CA2528897A1 (enExample) |
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| WO (1) | WO2004108153A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015091826A (ja) * | 2007-10-10 | 2015-05-14 | アンスティテュ、ナショナル、ド、ラ、サント、エ、ド、ラ、ルシェルシュ、メディカル（アンセルム）Ｉｎｓｔｉｔｕｔ Ｎａｔｉｏｎａｌ Ｄｅ Ｌａ Ｓａｎｔｅ Ｅｔ Ｄｅ Ｌａ Ｒｅｃｈｅｒｃｈｅ Ｍｅｄｉｃａｌ （Ｉｎｓｅｒｍ） | 癌治療用の組合せ製品 |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009536173A (ja) | 2006-05-10 | 2009-10-08 | メディカル エンザイムズ アクチエンゲゼルシャフト | グルタドン |
| US8173686B2 (en) | 2006-11-06 | 2012-05-08 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
| US8168661B2 (en) | 2006-11-06 | 2012-05-01 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
| US8168662B1 (en) | 2006-11-06 | 2012-05-01 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
| US8178564B2 (en) | 2006-11-06 | 2012-05-15 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
| EP3092235A2 (en) | 2014-01-06 | 2016-11-16 | Rhizen Pharmaceuticals S.A. | Novel inhibitors of glutaminase |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09502082A (ja) * | 1992-12-04 | 1997-03-04 | ロバーツ，ジョゼフ | 遺伝学的に操作されたグルタミナーゼ、および抗ウイルスと抗ガン治療におけるその使用 |
| WO2003039545A2 (en) * | 2001-11-07 | 2003-05-15 | Millennium Pharmaceuticals, Inc. | Carboline derivatives as inhibitors of ikb in the treatment of multiple myeloma and others cancers |
| WO2003039327A2 (en) * | 2001-11-02 | 2003-05-15 | Dana-Farber Cancer Institute | Methods and compositions for the diagnosis of cancer susceptibilities and defective dna repair mechanisms and treatment thereof |
| WO2003045330A2 (en) * | 2001-11-27 | 2003-06-05 | The Board Of Trustees Of The University Of Illinois | Materials and methods for making improved micelle compositions |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020094542A1 (en) * | 1988-04-15 | 2002-07-18 | Peter Leskovar | Drugs and methods for treating cancer |
| US4955857A (en) * | 1988-07-18 | 1990-09-11 | Shettigar Udipi R | Multi-enzyme bioreactor therapy for cancer |
| US5776458A (en) * | 1990-12-05 | 1998-07-07 | Pharmacia & Upjohn S.P.A. | Anthracycline-conjugates |
| DE4140003C2 (de) * | 1991-12-04 | 1994-09-29 | Joseph Prof Dr Roberts | Gentechnisch hergestellte Glutaminase und ihre Verwendung bei der antiviralen und Anti-Krebstherapie |
| DE69332637T2 (de) * | 1993-03-04 | 2003-10-23 | Matsushita Electric Industrial Co., Ltd. | Kokainderivat,Proteinkonjugat,davon,einen monoklonalen Antikörper produzierende Hybridom-Zellinie, Verfahren zur Herstellung der Hybridom-Zellinie und des monoklonalen Antikörpers |
| US6200754B1 (en) * | 1998-03-19 | 2001-03-13 | Variagenics, Inc. | Inhibitors of alternative alleles of genes encoding products that mediate cell response to environmental changes |
-
2003
- 2003-06-11 DE DE10326821A patent/DE10326821A1/de not_active Ceased
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2004
- 2004-06-11 AT AT04739811T patent/ATE350054T1/de active
- 2004-06-11 EP EP04739811A patent/EP1633394B1/de not_active Expired - Lifetime
- 2004-06-11 AU AU2004244755A patent/AU2004244755B9/en not_active Ceased
- 2004-06-11 JP JP2006515900A patent/JP2006527232A/ja active Pending
- 2004-06-11 DE DE502004002561T patent/DE502004002561D1/de not_active Expired - Lifetime
- 2004-06-11 CA CA002528897A patent/CA2528897A1/en not_active Abandoned
- 2004-06-11 ES ES04739811T patent/ES2280972T3/es not_active Expired - Lifetime
- 2004-06-11 US US10/560,317 patent/US20060263346A1/en not_active Abandoned
- 2004-06-11 WO PCT/EP2004/006320 patent/WO2004108153A1/de not_active Ceased
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09502082A (ja) * | 1992-12-04 | 1997-03-04 | ロバーツ，ジョゼフ | 遺伝学的に操作されたグルタミナーゼ、および抗ウイルスと抗ガン治療におけるその使用 |
| WO2003039327A2 (en) * | 2001-11-02 | 2003-05-15 | Dana-Farber Cancer Institute | Methods and compositions for the diagnosis of cancer susceptibilities and defective dna repair mechanisms and treatment thereof |
| WO2003039545A2 (en) * | 2001-11-07 | 2003-05-15 | Millennium Pharmaceuticals, Inc. | Carboline derivatives as inhibitors of ikb in the treatment of multiple myeloma and others cancers |
| WO2003045330A2 (en) * | 2001-11-27 | 2003-06-05 | The Board Of Trustees Of The University Of Illinois | Materials and methods for making improved micelle compositions |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015091826A (ja) * | 2007-10-10 | 2015-05-14 | アンスティテュ、ナショナル、ド、ラ、サント、エ、ド、ラ、ルシェルシュ、メディカル（アンセルム）Ｉｎｓｔｉｔｕｔ Ｎａｔｉｏｎａｌ Ｄｅ Ｌａ Ｓａｎｔｅ Ｅｔ Ｄｅ Ｌａ Ｒｅｃｈｅｒｃｈｅ Ｍｅｄｉｃａｌ （Ｉｎｓｅｒｍ） | 癌治療用の組合せ製品 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1633394B1 (de) | 2007-01-03 |
| ES2280972T3 (es) | 2007-09-16 |
| WO2004108153A1 (de) | 2004-12-16 |
| AU2004244755B9 (en) | 2009-12-24 |
| DE502004002561D1 (de) | 2007-02-15 |
| AU2004244755B2 (en) | 2009-06-25 |
| US20060263346A1 (en) | 2006-11-23 |
| EP1633394A1 (de) | 2006-03-15 |
| ATE350054T1 (de) | 2007-01-15 |
| DE10326821A1 (de) | 2005-01-05 |
| AU2004244755A1 (en) | 2004-12-16 |
| CA2528897A1 (en) | 2004-12-16 |
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