AU2004244755B9 - Combined pharmaceutical preparations for the treatment of cancer, containing glutaminase and antineoplastic anthracyclines or platinum compounds - Google Patents

Combined pharmaceutical preparations for the treatment of cancer, containing glutaminase and antineoplastic anthracyclines or platinum compounds Download PDF

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Publication number
AU2004244755B9
AU2004244755B9 AU2004244755A AU2004244755A AU2004244755B9 AU 2004244755 B9 AU2004244755 B9 AU 2004244755B9 AU 2004244755 A AU2004244755 A AU 2004244755A AU 2004244755 A AU2004244755 A AU 2004244755A AU 2004244755 B9 AU2004244755 B9 AU 2004244755B9
Authority
AU
Australia
Prior art keywords
glutaminase
compound
activity
anthracyclines
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2004244755A
Other languages
English (en)
Other versions
AU2004244755B2 (en
AU2004244755A1 (en
Inventor
Frank Leenders
Wenke Seifert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medical Enzymes AG
Original Assignee
Medical Enzymes AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Enzymes AG filed Critical Medical Enzymes AG
Publication of AU2004244755A1 publication Critical patent/AU2004244755A1/en
Application granted granted Critical
Publication of AU2004244755B2 publication Critical patent/AU2004244755B2/en
Publication of AU2004244755B9 publication Critical patent/AU2004244755B9/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/50—Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2004244755A 2003-06-11 2004-06-11 Combined pharmaceutical preparations for the treatment of cancer, containing glutaminase and antineoplastic anthracyclines or platinum compounds Ceased AU2004244755B9 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10326821A DE10326821A1 (de) 2003-06-11 2003-06-11 Pharmazeutische Kombinationspräparate zur Krebstherapie
DE10326821.9 2003-06-11
PCT/EP2004/006320 WO2004108153A1 (de) 2003-06-11 2004-06-11 Pharmazeutische kombinationspräparate zur krebstherapie enthaltend glutaminase und antineoplastische anthracycline oder platinverbindungen

Publications (3)

Publication Number Publication Date
AU2004244755A1 AU2004244755A1 (en) 2004-12-16
AU2004244755B2 AU2004244755B2 (en) 2009-06-25
AU2004244755B9 true AU2004244755B9 (en) 2009-12-24

Family

ID=33495036

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2004244755A Ceased AU2004244755B9 (en) 2003-06-11 2004-06-11 Combined pharmaceutical preparations for the treatment of cancer, containing glutaminase and antineoplastic anthracyclines or platinum compounds

Country Status (9)

Country Link
US (1) US20060263346A1 (enExample)
EP (1) EP1633394B1 (enExample)
JP (1) JP2006527232A (enExample)
AT (1) ATE350054T1 (enExample)
AU (1) AU2004244755B9 (enExample)
CA (1) CA2528897A1 (enExample)
DE (2) DE10326821A1 (enExample)
ES (1) ES2280972T3 (enExample)
WO (1) WO2004108153A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009536173A (ja) 2006-05-10 2009-10-08 メディカル エンザイムズ アクチエンゲゼルシャフト グルタドン
US8173686B2 (en) 2006-11-06 2012-05-08 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168661B2 (en) 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168662B1 (en) 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8178564B2 (en) 2006-11-06 2012-05-15 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
EP2047858A1 (en) * 2007-10-10 2009-04-15 Institut National De La Sante Et De La Recherche Medicale (Inserm) Combination products for treating cancer
EP3092235A2 (en) 2014-01-06 2016-11-16 Rhizen Pharmaceuticals S.A. Novel inhibitors of glutaminase

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020094542A1 (en) * 1988-04-15 2002-07-18 Peter Leskovar Drugs and methods for treating cancer
US4955857A (en) * 1988-07-18 1990-09-11 Shettigar Udipi R Multi-enzyme bioreactor therapy for cancer
US5776458A (en) * 1990-12-05 1998-07-07 Pharmacia & Upjohn S.P.A. Anthracycline-conjugates
DE4140003C2 (de) * 1991-12-04 1994-09-29 Joseph Prof Dr Roberts Gentechnisch hergestellte Glutaminase und ihre Verwendung bei der antiviralen und Anti-Krebstherapie
ATE361984T1 (de) * 1992-12-04 2007-06-15 Me Medical Enzymes Ag Gentechnologisch hergestellte glutaminase und ihre verwendung in therapie
DE69332637T2 (de) * 1993-03-04 2003-10-23 Matsushita Electric Industrial Co., Ltd. Kokainderivat,Proteinkonjugat,davon,einen monoklonalen Antikörper produzierende Hybridom-Zellinie, Verfahren zur Herstellung der Hybridom-Zellinie und des monoklonalen Antikörpers
US20020115609A1 (en) * 1997-07-14 2002-08-22 Hayat Onyuksel Materials and methods for making improved micelle compositions
US6200754B1 (en) * 1998-03-19 2001-03-13 Variagenics, Inc. Inhibitors of alternative alleles of genes encoding products that mediate cell response to environmental changes
CA2465949A1 (en) * 2001-11-02 2003-05-15 Dana-Farber Cancer Institute Methods and compositions for the diagnosis of cancer susceptibilities and defective dna repair mechanisms and treatment thereof
WO2003039545A2 (en) * 2001-11-07 2003-05-15 Millennium Pharmaceuticals, Inc. Carboline derivatives as inhibitors of ikb in the treatment of multiple myeloma and others cancers

Also Published As

Publication number Publication date
EP1633394B1 (de) 2007-01-03
ES2280972T3 (es) 2007-09-16
WO2004108153A1 (de) 2004-12-16
DE502004002561D1 (de) 2007-02-15
AU2004244755B2 (en) 2009-06-25
JP2006527232A (ja) 2006-11-30
US20060263346A1 (en) 2006-11-23
EP1633394A1 (de) 2006-03-15
ATE350054T1 (de) 2007-01-15
DE10326821A1 (de) 2005-01-05
AU2004244755A1 (en) 2004-12-16
CA2528897A1 (en) 2004-12-16

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
SREP Specification republished
MK14 Patent ceased section 143(a) (annual fees not paid) or expired