JP2006523437A - レセプター複合体 - Google Patents
レセプター複合体 Download PDFInfo
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- JP2006523437A JP2006523437A JP2004570696A JP2004570696A JP2006523437A JP 2006523437 A JP2006523437 A JP 2006523437A JP 2004570696 A JP2004570696 A JP 2004570696A JP 2004570696 A JP2004570696 A JP 2004570696A JP 2006523437 A JP2006523437 A JP 2006523437A
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- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
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| GB0228112A GB0228112D0 (en) | 2002-12-03 | 2002-12-03 | Receptors |
| GB0304090A GB0304090D0 (en) | 2003-02-22 | 2003-02-22 | Receptors |
| GB0308309A GB0308309D0 (en) | 2003-04-10 | 2003-04-10 | Receptors |
| US47590603P | 2003-06-05 | 2003-06-05 | |
| GB0314113A GB0314113D0 (en) | 2003-06-18 | 2003-06-18 | Receptors |
| GB0316354A GB0316354D0 (en) | 2003-07-11 | 2003-07-11 | Receptors |
| PCT/GB2003/005104 WO2004050705A2 (en) | 2002-12-03 | 2003-11-25 | Complexes of receptors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006523437A true JP2006523437A (ja) | 2006-10-19 |
| JP2006523437A5 JP2006523437A5 (https=) | 2006-12-14 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004570696A Withdrawn JP2006523437A (ja) | 2002-12-03 | 2003-11-25 | レセプター複合体 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20060135418A1 (https=) |
| EP (1) | EP1567553A2 (https=) |
| JP (1) | JP2006523437A (https=) |
| AU (1) | AU2003286263A1 (https=) |
| WO (1) | WO2004050705A2 (https=) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014505471A (ja) * | 2010-12-27 | 2014-03-06 | エーピーオー‐ティー ビー．ヴイ． | アポトーシスを誘導する架橋ポリペプチド |
| JP2018522061A (ja) * | 2015-05-20 | 2018-08-09 | ▲広▼▲東▼香雪精准医▲療▼技▲術▼有限公司Ｇｕａｎｇｄｏｎｇ Ｘｉａｎｇｘｕｅ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ， Ｌｔｄ． | 安定した可溶性ヘテロ二量体ｔｃｒ |
| JP2020501508A (ja) * | 2016-09-15 | 2020-01-23 | クアドルセプト バイオ リミテッド | 多量体、四量体および八量体 |
| US10946104B2 (en) | 2012-01-13 | 2021-03-16 | Apo-Tb.V. | Aberrant cell-restricted immunoglobulins provided with a toxic moiety |
| US11098115B2 (en) | 2011-09-29 | 2021-08-24 | Apo-T B.V. | Multi-specific binding molecules targeting aberrant cells |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US8772451B2 (en) * | 2003-11-10 | 2014-07-08 | Altor Bioscience Corporation | Soluble TCR molecules and methods of use |
| US20060122783A1 (en) * | 2004-08-24 | 2006-06-08 | Ishikawa Muriel Y | System and method for heightening a humoral immune response |
| US20060047434A1 (en) * | 2004-08-24 | 2006-03-02 | Ishikawa Muriel Y | System and method related to improving an immune system |
| US20060182742A1 (en) * | 2004-08-24 | 2006-08-17 | Ishikawa Muriel Y | System and method for magnifying a humoral immune response |
| US20060047435A1 (en) * | 2004-08-24 | 2006-03-02 | Ishikawa Muriel Y | System and method related to augmenting an immune system |
| US20060095211A1 (en) * | 2003-12-05 | 2006-05-04 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | System and method for modulating a cell mediated immune response |
| US20060116824A1 (en) * | 2004-12-01 | 2006-06-01 | Ishikawa Muriel Y | System and method for modulating a humoral immune response |
| US20060047433A1 (en) * | 2004-08-24 | 2006-03-02 | Ishikawa Muriel Y | System and method related to enhancing an immune system |
| US20060047437A1 (en) * | 2004-08-25 | 2006-03-02 | Ishikawa Muriel Y | System and method for heightening an immune response |
| US20060047436A1 (en) * | 2004-08-25 | 2006-03-02 | Ishikawa Muriel Y | System and method for magnifying an immune response |
| US20060122784A1 (en) * | 2004-12-03 | 2006-06-08 | Ishikawa Muriel Y | System and method for augmenting a humoral immune response |
| US20070196362A1 (en) * | 2004-08-24 | 2007-08-23 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Computational methods and systems to bolster an immune response |
| US20060047439A1 (en) * | 2004-08-24 | 2006-03-02 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | System and method for improving a humoral immune response |
| US20070265818A1 (en) * | 2004-08-24 | 2007-11-15 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Computational methods and systems for heightening cell-mediated immune response |
| US20070207492A1 (en) * | 2004-08-24 | 2007-09-06 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Computational methods and systems to adjust a humoral immune response |
| US20070198196A1 (en) * | 2004-08-24 | 2007-08-23 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Computational systems and methods relating to ameliorating an immune system |
| US20070265819A1 (en) * | 2004-08-24 | 2007-11-15 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Computational methods and systems for improving cell-mediated immune response |
| AU2005291039A1 (en) * | 2004-10-01 | 2006-04-13 | Avidex Ltd. | T-cell receptors containing a non-native disulfide interchain bond linked to therapeutic agents |
| GB0427585D0 (en) * | 2004-12-16 | 2005-01-19 | Avidex Ltd | Assay |
| CN103555733A (zh) | 2005-01-05 | 2014-02-05 | F-星生物技术研究与开发有限公司 | 分子中互补决定区以外的区域中工程改造了的具有结合特性的合成免疫球蛋白结构域 |
| GB0511124D0 (en) * | 2005-06-01 | 2005-07-06 | Avidex Ltd | High affinity melan-a t cell receptors |
| CA2634292A1 (en) * | 2005-12-20 | 2007-06-28 | Erasmus University Medical Center Rotterdam | Apoptosis-inducing protein complexes and therapeutic use thereof |
| EP1870418A1 (en) | 2006-06-20 | 2007-12-26 | GSF-Forschungszentrum für Umwelt und Gesundheit GmbH | Allorestricted peptide-specific T cells |
| AT503889B1 (de) | 2006-07-05 | 2011-12-15 | Star Biotechnologische Forschungs Und Entwicklungsges M B H F | Multivalente immunglobuline |
| AT503861B1 (de) | 2006-07-05 | 2008-06-15 | F Star Biotech Forsch & Entw | Verfahren zur manipulation von t-zell-rezeptoren |
| WO2008039818A2 (en) | 2006-09-26 | 2008-04-03 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Modified t cell receptors and related materials and methods |
| EP3241842B1 (en) | 2007-06-26 | 2024-01-31 | F-star Therapeutics Limited | Display of binding agents |
| GB0712670D0 (en) | 2007-06-29 | 2007-08-08 | King S College London | Isolated peptides and uses thereof |
| EP2113255A1 (en) | 2008-05-02 | 2009-11-04 | f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. | Cytotoxic immunoglobulin |
| GB0816096D0 (en) * | 2008-09-04 | 2008-10-15 | Medigene Ltd | Diabetes t cell receptors |
| US9821073B2 (en) | 2010-12-27 | 2017-11-21 | Apo-T B.V. | Polypeptide that binds aberrant cells and induces apoptosis |
| US20220275043A1 (en) | 2018-07-17 | 2022-09-01 | Massachusetts Institute Of Technology | Soluble multimeric immunoglobulin-scaffold based fusion proteins and uses thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4625275A (en) * | 1984-04-03 | 1986-11-25 | Republic Money Orders, Inc. | Apparatus for dispensing money orders |
| CA2250166A1 (en) * | 1996-03-28 | 1997-10-02 | The Johns Hopkins University | Soluble divalent and multivalent heterodimeric analogs of proteins |
| US6211342B1 (en) * | 1996-07-18 | 2001-04-03 | Children's Hospital Medical Center | Multivalent MHC complex peptide fusion protein complex for stimulating specific T cell function |
| AU6685698A (en) * | 1997-03-07 | 1998-09-22 | Sunol Molecular Corporation | Fusion proteins comprising bacteriophage coat protein and a single-chain t cell receptor |
| WO1999060120A2 (en) * | 1998-05-19 | 1999-11-25 | Avidex Limited | Soluble t cell receptor |
| ES2293748T3 (es) * | 1998-10-21 | 2008-03-16 | Altor Bioscience Corporation | Moleculas de fijacion poliespecificas y usos de las mismas. |
| WO2001062908A2 (en) * | 2000-02-22 | 2001-08-30 | Ahuva Nissim | Chimeric and tcr phage display libraries, chimeric and tcr reagents and methods of use thereof |
| EP2322228B1 (en) * | 2000-06-05 | 2018-01-10 | Altor BioScience Corporation | T cell receptor fusion proteins and conjugates and methods of use thereof |
| US6811785B2 (en) * | 2001-05-07 | 2004-11-02 | Mount Sinai School Of Medicine Of New York University | Multivalent MHC class II—peptide chimeras |
-
2003
- 2003-11-25 JP JP2004570696A patent/JP2006523437A/ja not_active Withdrawn
- 2003-11-25 AU AU2003286263A patent/AU2003286263A1/en not_active Abandoned
- 2003-11-25 WO PCT/GB2003/005104 patent/WO2004050705A2/en not_active Ceased
- 2003-11-25 US US10/535,965 patent/US20060135418A1/en not_active Abandoned
- 2003-11-25 EP EP03777006A patent/EP1567553A2/en not_active Withdrawn
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014505471A (ja) * | 2010-12-27 | 2014-03-06 | エーピーオー‐ティー ビー．ヴイ． | アポトーシスを誘導する架橋ポリペプチド |
| US11098115B2 (en) | 2011-09-29 | 2021-08-24 | Apo-T B.V. | Multi-specific binding molecules targeting aberrant cells |
| US10946104B2 (en) | 2012-01-13 | 2021-03-16 | Apo-Tb.V. | Aberrant cell-restricted immunoglobulins provided with a toxic moiety |
| JP2018522061A (ja) * | 2015-05-20 | 2018-08-09 | ▲広▼▲東▼香雪精准医▲療▼技▲術▼有限公司Ｇｕａｎｇｄｏｎｇ Ｘｉａｎｇｘｕｅ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ， Ｌｔｄ． | 安定した可溶性ヘテロ二量体ｔｃｒ |
| JP2020501508A (ja) * | 2016-09-15 | 2020-01-23 | クアドルセプト バイオ リミテッド | 多量体、四量体および八量体 |
| JP2023015311A (ja) * | 2016-09-15 | 2023-01-31 | クアドルセプト バイオ リミテッド | 多量体、四量体および八量体 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20060135418A1 (en) | 2006-06-22 |
| AU2003286263A1 (en) | 2004-06-23 |
| AU2003286263A8 (en) | 2004-06-23 |
| WO2004050705A2 (en) | 2004-06-17 |
| EP1567553A2 (en) | 2005-08-31 |
| WO2004050705A3 (en) | 2004-11-25 |
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