JP2006523091A - ヒト胚性幹細胞の心筋細胞への分化 - Google Patents

ヒト胚性幹細胞の心筋細胞への分化 Download PDF

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JP2006523091A
JP2006523091A JP2006503961A JP2006503961A JP2006523091A JP 2006523091 A JP2006523091 A JP 2006523091A JP 2006503961 A JP2006503961 A JP 2006503961A JP 2006503961 A JP2006503961 A JP 2006503961A JP 2006523091 A JP2006523091 A JP 2006523091A
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ママリー,クリスティン・リンゼイ
ドゥーフェンダンス,ペトルス・アドリアヌス・フレデリック・マリーア
テルトーレン,レオン・ヘラルドゥス・ヨーゼフ
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イーエス・セル・インターナショナル・プライヴェート・リミテッド
ネザーランズ・インスティテュート・フォール・オントヴィッケリングスビオロヒー
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657Cardiomyocytes; Heart cells
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells

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JP2006503961A 2003-03-11 2004-03-11 ヒト胚性幹細胞の心筋細胞への分化 Pending JP2006523091A (ja)

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Application Number Priority Date Filing Date Title
AU2003901099A AU2003901099A0 (en) 2003-03-11 2003-03-11 Methods of inducing differentiation of stem cells
PCT/AU2004/000302 WO2004081205A1 (en) 2003-03-11 2004-03-11 Differentiation of human embryonic stem cells to cardiomyocytes

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JP2006523091A true JP2006523091A (ja) 2006-10-12
JP2006523091A5 JP2006523091A5 (https=) 2007-05-24

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US (1) US20070161107A1 (https=)
EP (1) EP1608740A4 (https=)
JP (1) JP2006523091A (https=)
AU (1) AU2003901099A0 (https=)
CA (1) CA2518508A1 (https=)
GB (1) GB2415437A (https=)
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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010047133A1 (ja) * 2008-10-24 2010-04-29 株式会社クラレ 細胞保存方法、及び細胞輸送方法
WO2010134606A1 (ja) 2009-05-22 2010-11-25 学校法人 東京女子医科大学 胚性幹細胞或いは人工多能性幹細胞の分化誘導方法
JP2013531497A (ja) * 2010-06-13 2013-08-08 インスティチュート・オブ・バイオフィジックス,チャイニーズ・アカデミー・オブ・サイエンシズ 幹細胞から心筋細胞を調製するための方法および組成物ならびにその使用
JP2014525268A (ja) * 2011-08-30 2014-09-29 ザ ジェイ. デヴィッド グラッドストーン インスティテューツ 心筋細胞を生成するための方法
WO2015025958A1 (ja) * 2013-08-23 2015-02-26 国立大学法人大阪大学 ペースメーカー組織片の製造方法
US11339371B2 (en) 2012-07-23 2022-05-24 Institute Of Biophysics, Chinese Academy Of Sciences Method for inducing pluripotent stem cells to differentiate into ventricular myocytes in vitro
WO2024162286A1 (ja) 2023-01-31 2024-08-08 富士フイルム株式会社 薬剤の評価方法、試薬およびキット

Families Citing this family (29)

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US7732199B2 (en) 2001-07-12 2010-06-08 Geron Corporation Process for making transplantable cardiomyocytes from human embryonic stem cells
WO2003006950A2 (en) 2001-07-12 2003-01-23 Geron Corporation Cells of the cardiomyocyte lineage produced from human pluripotent stem cells
US7452718B2 (en) 2004-03-26 2008-11-18 Geron Corporation Direct differentiation method for making cardiomyocytes from human embryonic stem cells
CA2569242A1 (en) * 2004-06-01 2005-12-15 Es Cell International Pte Ltd Improved cardiomyocyte differentiation
CA2611809C (en) 2005-06-22 2018-06-19 Geron Corporation Differentiation of primate pluripotent stem cells to cardiomyocyte-lineage cells
US20090227032A1 (en) 2005-12-13 2009-09-10 Kyoto University Nuclear reprogramming factor and induced pluripotent stem cells
BRPI0619794B8 (pt) 2005-12-13 2022-06-14 Univ Kyoto Uso de um fator de reprogramação, agente para a preparação de uma célula-tronco pluripotente induzida a partir de uma célula somática e métodos para preparar uma célula- tronco pluripotente induzida método e para preparar uma célula somática e uso de células-tronco pluripotentes induzidas
US8278104B2 (en) 2005-12-13 2012-10-02 Kyoto University Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2
US8129187B2 (en) 2005-12-13 2012-03-06 Kyoto University Somatic cell reprogramming by retroviral vectors encoding Oct3/4. Klf4, c-Myc and Sox2
WO2008073331A2 (en) * 2006-12-07 2008-06-19 Teva Pharmaceutical Industries Ltd. Method of generation and expansion of tissue-progenitor cells and mature tissue cells from intact bone marrow or intact umbilical cord tissue
US20080300642A1 (en) * 2007-05-30 2008-12-04 Japan As Represented By President Of National Cardiovascular Center Regeneration treatment apparatus, operating method thereof, and regeneration treatment method
US9213999B2 (en) 2007-06-15 2015-12-15 Kyoto University Providing iPSCs to a customer
JP2008307007A (ja) 2007-06-15 2008-12-25 Bayer Schering Pharma Ag 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
WO2009036220A2 (en) * 2007-09-12 2009-03-19 The Regents Of The University Of California Compositions and methods for improving the functional efficacy of stem cell-derived cardiomyocytes
JP5558097B2 (ja) 2007-12-10 2014-07-23 国立大学法人京都大学 効率的な核初期化方法
US9683232B2 (en) 2007-12-10 2017-06-20 Kyoto University Efficient method for nuclear reprogramming
CN101939418A (zh) 2008-01-30 2011-01-05 杰龙公司 用于培养干细胞衍生的心肌细胞的合成表面
SG188904A1 (en) 2008-03-17 2013-04-30 Scripps Research Inst Combined chemical and genetic approaches for generation of induced pluripotent stem cells
SG10201400329YA (en) 2008-05-02 2014-05-29 Univ Kyoto Method of nuclear reprogramming
BRPI0922572A2 (pt) 2008-12-17 2019-09-24 Scripps Research Inst método para cultivar células pluripotentes, cultura de células de mamífero pluripotentes, meio de cultura de célula, célula animal pluripotente isolada, e, método para aumentar a pluripotência de uma célula de mamífero.
AU2010306627B2 (en) 2009-10-16 2014-07-17 The Scripps Research Institute Induction of pluripotent cells
CA2800498C (en) 2010-03-31 2021-11-16 The Scripps Research Institute Reprogramming cells
EP3399026B1 (en) 2010-06-14 2024-06-26 The Scripps Research Institute Reprogramming of cells to a new fate
WO2012087965A2 (en) 2010-12-22 2012-06-28 Fate Therapauetics, Inc. Cell culture platform for single cell sorting and enhanced reprogramming of ipscs
EP2948542A4 (en) 2013-01-23 2016-07-13 Ronald Li MANIPULATED PHYSICAL ORIENTATION OF CARDIOMYOCYTES FROM STEM CELLS
US10087436B2 (en) 2014-02-06 2018-10-02 The Regents Of The University Of California Electrophysiologically mature cardiomyocytes and methods for making same
SG11201606934SA (en) 2014-03-04 2016-09-29 Fate Therapeutics Inc Improved reprogramming methods and cell culture platforms
SG10202111851YA (en) 2015-10-16 2021-12-30 Fate Therapeutics Inc Platform for the Induction & Maintenance of Ground State Pluripotency
CN113662985B (zh) 2021-09-07 2022-06-24 北京中医药大学 具有促进干细胞定向分化为心肌细胞作用的中药组合物、中药有效组分组合物及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003010303A1 (en) * 2001-07-24 2003-02-06 Es Cell International Pte Ltd Methods of inducing differentiation of stem cells

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2493588C (en) * 2002-07-26 2012-09-11 Wisconsin Alumni Research Foundation Functional cardiomyocytes from human embryonic stem cells
WO2005054448A1 (en) * 2003-12-04 2005-06-16 Guhathakurta Dr Soma A novel process and method for deriving cardiomyocyte precursors from bone-marrow stem cells

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003010303A1 (en) * 2001-07-24 2003-02-06 Es Cell International Pte Ltd Methods of inducing differentiation of stem cells

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010047133A1 (ja) * 2008-10-24 2010-04-29 株式会社クラレ 細胞保存方法、及び細胞輸送方法
JPWO2010047133A1 (ja) * 2008-10-24 2012-03-22 株式会社クラレ 細胞保存方法、及び細胞輸送方法
WO2010134606A1 (ja) 2009-05-22 2010-11-25 学校法人 東京女子医科大学 胚性幹細胞或いは人工多能性幹細胞の分化誘導方法
JP2013531497A (ja) * 2010-06-13 2013-08-08 インスティチュート・オブ・バイオフィジックス,チャイニーズ・アカデミー・オブ・サイエンシズ 幹細胞から心筋細胞を調製するための方法および組成物ならびにその使用
US9273286B2 (en) 2010-06-13 2016-03-01 Institute Of Biophysics, Chinese Academy Of Sciences Methods and compositions for preparing cardiomyocytes from stem cells and uses thereof
US10590386B2 (en) 2010-06-13 2020-03-17 Insitute Of Biophysics, Chinese Academy Of Sciences Methods and compositions for preparing cardiomyocytes from stem cells and uses thereof
JP2014525268A (ja) * 2011-08-30 2014-09-29 ザ ジェイ. デヴィッド グラッドストーン インスティテューツ 心筋細胞を生成するための方法
US11339371B2 (en) 2012-07-23 2022-05-24 Institute Of Biophysics, Chinese Academy Of Sciences Method for inducing pluripotent stem cells to differentiate into ventricular myocytes in vitro
WO2015025958A1 (ja) * 2013-08-23 2015-02-26 国立大学法人大阪大学 ペースメーカー組織片の製造方法
WO2024162286A1 (ja) 2023-01-31 2024-08-08 富士フイルム株式会社 薬剤の評価方法、試薬およびキット
KR20250130369A (ko) 2023-01-31 2025-09-01 후지필름 가부시키가이샤 약제의 평가 방법, 시약 및 키트
EP4660316A1 (en) 2023-01-31 2025-12-10 FUJIFILM Corporation Drug evaluation method, reagent and kit

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GB2415437A (en) 2005-12-28
GB0520673D0 (en) 2005-11-16
WO2004081205A8 (en) 2004-10-28
WO2004081205A1 (en) 2004-09-23
CA2518508A1 (en) 2004-09-23
US20070161107A1 (en) 2007-07-12
EP1608740A4 (en) 2007-05-09
AU2003901099A0 (en) 2003-03-27
EP1608740A1 (en) 2005-12-28

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