JP2006521793A - Egfrインヒビター薬物に応答性の遺伝子発現マーカー - Google Patents

Egfrインヒビター薬物に応答性の遺伝子発現マーカー Download PDF

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JP2006521793A
JP2006521793A JP2006503407A JP2006503407A JP2006521793A JP 2006521793 A JP2006521793 A JP 2006521793A JP 2006503407 A JP2006503407 A JP 2006503407A JP 2006503407 A JP2006503407 A JP 2006503407A JP 2006521793 A JP2006521793 A JP 2006521793A
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cancer
expression
gene
patient
treatment
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デービッド アガス,
スティーブ シャク,
モウリーン ティー. クロニン,
ジョフレ ビー. ベイカー,
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ゲノミック ヘルス, インコーポレイテッド
セダーズ−シナイ メディカル センター
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Publication of JP2006521793A publication Critical patent/JP2006521793A/ja
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2006503407A 2003-02-06 2004-02-05 Egfrインヒビター薬物に応答性の遺伝子発現マーカー Pending JP2006521793A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44596803P 2003-02-06 2003-02-06
PCT/US2004/003596 WO2004071572A2 (en) 2003-02-06 2004-02-05 Gene expression markers for response to egfr inhibitor drugs

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JP2006521793A true JP2006521793A (ja) 2006-09-28
JP2006521793A5 JP2006521793A5 (https=) 2007-03-22

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US (2) US20040157255A1 (https=)
EP (1) EP1590487A2 (https=)
JP (1) JP2006521793A (https=)
AU (2) AU2004211955B2 (https=)
CA (1) CA2515096A1 (https=)
WO (1) WO2004071572A2 (https=)

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WO2010064702A1 (ja) * 2008-12-05 2010-06-10 国立大学法人 東京大学 癌の予後を予測するためのバイオマーカー
WO2010084998A1 (en) * 2009-01-26 2010-07-29 Kyushu University, National University Corporation A method of predicting the efficacy of a drug
JP2014526680A (ja) * 2011-09-12 2014-10-06 ユニヴェルシテイト ヘント 結腸直腸ガンのニューレグリン−1に基づく予後予測及び治療層別化
JP2017161531A (ja) * 2007-10-19 2017-09-14 セル・シグナリング・テクノロジー・インコーポレイテツド 癌の分類および使用法
KR20180010138A (ko) * 2016-07-20 2018-01-30 연세대학교 산학협력단 암 예후 예측을 위한 조성물 및 이를 포함하는 키트

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ES2537631T3 (es) 2004-05-27 2015-06-10 The Regents Of The University Of Colorado Métodos para la predicción del resultado clínico para inhibidores del receptor del factor de crecimiento epidérmico para pacientes de cáncer
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JP5240739B2 (ja) 2007-04-13 2013-07-17 オーエスアイ・フアーマシユーテイカルズ・エル・エル・シー キナーゼ阻害剤に対する抗癌応答を予測する生物学的マーカー
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JP2010540960A (ja) 2007-10-03 2010-12-24 オーエスアイ・ファーマスーティカルズ・インコーポレーテッド インスリン様成長因子−1受容体キナーゼ阻害剤に対する抗癌反応を予測する生物学的マーカー
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CN101910414B (zh) * 2007-11-07 2016-01-13 健泰科生物技术公司 用于评估b细胞淋巴瘤对抗cd40抗体治疗的响应性的方法和组合物
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CN102459639A (zh) 2009-04-18 2012-05-16 健泰科生物技术公司 用于评估b细胞淋巴瘤对抗cd40抗体治疗的响应性的方法
JP5795311B2 (ja) 2009-07-15 2015-10-14 ネステク ソシエテ アノニム 抗体ベースのアレイを使用する胃癌療法のための薬物選択
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Cited By (6)

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Publication number Priority date Publication date Assignee Title
JP2017161531A (ja) * 2007-10-19 2017-09-14 セル・シグナリング・テクノロジー・インコーポレイテツド 癌の分類および使用法
WO2010064702A1 (ja) * 2008-12-05 2010-06-10 国立大学法人 東京大学 癌の予後を予測するためのバイオマーカー
WO2010084998A1 (en) * 2009-01-26 2010-07-29 Kyushu University, National University Corporation A method of predicting the efficacy of a drug
JP2014526680A (ja) * 2011-09-12 2014-10-06 ユニヴェルシテイト ヘント 結腸直腸ガンのニューレグリン−1に基づく予後予測及び治療層別化
KR20180010138A (ko) * 2016-07-20 2018-01-30 연세대학교 산학협력단 암 예후 예측을 위한 조성물 및 이를 포함하는 키트
KR101941054B1 (ko) 2016-07-20 2019-01-23 연세대학교 산학협력단 암 예후 예측을 위한 조성물 및 이를 포함하는 키트

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US20080176229A1 (en) 2008-07-24
AU2004211955A1 (en) 2004-08-26
WO2004071572A3 (en) 2005-01-13
AU2009208748A1 (en) 2009-09-10
EP1590487A2 (en) 2005-11-02
WO2004071572A2 (en) 2004-08-26
US20040157255A1 (en) 2004-08-12
CA2515096A1 (en) 2004-08-26
AU2004211955B2 (en) 2009-05-14

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