AU2004211955B2 - Gene expression markers for response to EGFR inhibitor drugs - Google Patents
Gene expression markers for response to EGFR inhibitor drugs Download PDFInfo
- Publication number
- AU2004211955B2 AU2004211955B2 AU2004211955A AU2004211955A AU2004211955B2 AU 2004211955 B2 AU2004211955 B2 AU 2004211955B2 AU 2004211955 A AU2004211955 A AU 2004211955A AU 2004211955 A AU2004211955 A AU 2004211955A AU 2004211955 B2 AU2004211955 B2 AU 2004211955B2
- Authority
- AU
- Australia
- Prior art keywords
- cancer
- expression
- patient
- treatment
- normalized
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2009208748A AU2009208748A1 (en) | 2003-02-06 | 2009-08-14 | Gene expression markers for response to EGFR inhibitor drugs |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44596803P | 2003-02-06 | 2003-02-06 | |
| US60/445,968 | 2003-02-06 | ||
| PCT/US2004/003596 WO2004071572A2 (en) | 2003-02-06 | 2004-02-05 | Gene expression markers for response to egfr inhibitor drugs |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2009208748A Division AU2009208748A1 (en) | 2003-02-06 | 2009-08-14 | Gene expression markers for response to EGFR inhibitor drugs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2004211955A1 AU2004211955A1 (en) | 2004-08-26 |
| AU2004211955B2 true AU2004211955B2 (en) | 2009-05-14 |
Family
ID=32869443
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2004211955A Ceased AU2004211955B2 (en) | 2003-02-06 | 2004-02-05 | Gene expression markers for response to EGFR inhibitor drugs |
| AU2009208748A Abandoned AU2009208748A1 (en) | 2003-02-06 | 2009-08-14 | Gene expression markers for response to EGFR inhibitor drugs |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2009208748A Abandoned AU2009208748A1 (en) | 2003-02-06 | 2009-08-14 | Gene expression markers for response to EGFR inhibitor drugs |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20040157255A1 (https=) |
| EP (1) | EP1590487A2 (https=) |
| JP (1) | JP2006521793A (https=) |
| AU (2) | AU2004211955B2 (https=) |
| CA (1) | CA2515096A1 (https=) |
| WO (1) | WO2004071572A2 (https=) |
Families Citing this family (59)
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| ATE520979T1 (de) * | 2005-08-24 | 2011-09-15 | Bristol Myers Squibb Co | Biomarker und verfahren zur bestimmung der empfindlichkeit gegenüber modulatoren des egf(epidermal growth factor)-rezeptors |
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| JP5240739B2 (ja) | 2007-04-13 | 2013-07-17 | オーエスアイ・フアーマシユーテイカルズ・エル・エル・シー | キナーゼ阻害剤に対する抗癌応答を予測する生物学的マーカー |
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| WO2009021680A1 (en) * | 2007-08-14 | 2009-02-19 | F. Hoffmann-La Roche Ag | Predictive marker for egfr inhibitor treatment |
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| KR20100037637A (ko) * | 2007-08-14 | 2010-04-09 | 에프. 호프만-라 로슈 아게 | Egfr 억제제 치료에 대한 예측 마커 |
| JP2010540960A (ja) | 2007-10-03 | 2010-12-24 | オーエスアイ・ファーマスーティカルズ・インコーポレーテッド | インスリン様成長因子−1受容体キナーゼ阻害剤に対する抗癌反応を予測する生物学的マーカー |
| JP2011501660A (ja) | 2007-10-03 | 2011-01-13 | オーエスアイ・ファーマスーティカルズ・インコーポレーテッド | インスリン様成長因子−1受容体キナーゼ阻害剤に対する抗癌反応を予測する生物学的マーカー |
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| JPWO2010064702A1 (ja) * | 2008-12-05 | 2012-05-10 | 国立大学法人 東京大学 | 癌の予後を予測するためのバイオマーカー |
| WO2010084998A1 (en) * | 2009-01-26 | 2010-07-29 | Kyushu University, National University Corporation | A method of predicting the efficacy of a drug |
| US20110171124A1 (en) * | 2009-02-26 | 2011-07-14 | Osi Pharmaceuticals, Inc. | In situ methods for monitoring the EMT status of tumor cells in vivo |
| KR101787768B1 (ko) | 2009-04-18 | 2017-10-18 | 제넨테크, 인크. | 항-cd40 항체를 사용한 치료에 대한 b-세포 림프종의 반응성 평가를 위한 방법 |
| AU2010273319B2 (en) * | 2009-07-15 | 2015-01-22 | Nestec S.A. | Drug selection for gastric cancer therapy using antibody-based arrays |
| US10731221B2 (en) | 2009-12-11 | 2020-08-04 | Dignity Health | Diagnosing IDH1 related subgroups and treatment of cancer |
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| CA2783665A1 (en) * | 2010-03-03 | 2011-09-09 | OSI Pharmaceuticals, LLC | Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors |
| CA2783656A1 (en) | 2010-03-03 | 2011-09-09 | OSI Pharmaceuticals, LLC | Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors |
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| JP6186575B2 (ja) | 2011-09-02 | 2017-08-30 | ダイアテック ホールディングス, インコーポレイテッドDiaTech Holdings, Inc. | 治療有効性を判定するためのシグナル経路タンパク質のプロファイリング |
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| CN104946597A (zh) * | 2015-03-23 | 2015-09-30 | 大连医科大学附属第一医院 | 稳定表达GFP的shRNA靶向干扰YB-1基因人肺腺癌A549细胞株 |
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-
2004
- 2004-02-05 CA CA002515096A patent/CA2515096A1/en not_active Abandoned
- 2004-02-05 WO PCT/US2004/003596 patent/WO2004071572A2/en not_active Ceased
- 2004-02-05 EP EP04708653A patent/EP1590487A2/en not_active Withdrawn
- 2004-02-05 JP JP2006503407A patent/JP2006521793A/ja active Pending
- 2004-02-05 AU AU2004211955A patent/AU2004211955B2/en not_active Ceased
- 2004-02-06 US US10/773,951 patent/US20040157255A1/en not_active Abandoned
-
2007
- 2007-05-30 US US11/755,697 patent/US20080176229A1/en not_active Abandoned
-
2009
- 2009-08-14 AU AU2009208748A patent/AU2009208748A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006521793A (ja) | 2006-09-28 |
| US20040157255A1 (en) | 2004-08-12 |
| WO2004071572A3 (en) | 2005-01-13 |
| CA2515096A1 (en) | 2004-08-26 |
| WO2004071572A2 (en) | 2004-08-26 |
| AU2009208748A1 (en) | 2009-09-10 |
| EP1590487A2 (en) | 2005-11-02 |
| US20080176229A1 (en) | 2008-07-24 |
| AU2004211955A1 (en) | 2004-08-26 |
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