SI2176430T1 - Napovedni marker za zdravljenje z inhibitorjem EGFR - Google Patents

Napovedni marker za zdravljenje z inhibitorjem EGFR

Info

Publication number
SI2176430T1
SI2176430T1 SI200830833T SI200830833T SI2176430T1 SI 2176430 T1 SI2176430 T1 SI 2176430T1 SI 200830833 T SI200830833 T SI 200830833T SI 200830833 T SI200830833 T SI 200830833T SI 2176430 T1 SI2176430 T1 SI 2176430T1
Authority
SI
Slovenia
Prior art keywords
egfr inhibitor
inhibitor treatment
predictive marker
predictive
marker
Prior art date
Application number
SI200830833T
Other languages
English (en)
Inventor
Paul Delmar
Barbara Klughammer
Verena Lutz
Patricia Mcloughlin
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of SI2176430T1 publication Critical patent/SI2176430T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
SI200830833T 2007-08-14 2008-08-07 Napovedni marker za zdravljenje z inhibitorjem EGFR SI2176430T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07114302 2007-08-14
PCT/EP2008/006523 WO2009021684A2 (en) 2007-08-14 2008-08-07 Predictive marker for egfr inhibitor treatment
EP20080785429 EP2176430B9 (en) 2007-08-14 2008-08-07 Predictive marker for egfr inhibitor treatment

Publications (1)

Publication Number Publication Date
SI2176430T1 true SI2176430T1 (sl) 2013-01-31

Family

ID=40227562

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200830833T SI2176430T1 (sl) 2007-08-14 2008-08-07 Napovedni marker za zdravljenje z inhibitorjem EGFR

Country Status (14)

Country Link
US (2) US20110184005A1 (sl)
EP (1) EP2176430B9 (sl)
JP (1) JP5368445B2 (sl)
KR (1) KR101169246B1 (sl)
CN (1) CN101827947B (sl)
AU (1) AU2008286337B2 (sl)
CA (1) CA2695473C (sl)
DK (1) DK2176430T5 (sl)
ES (1) ES2395881T3 (sl)
IL (1) IL203647A (sl)
MX (1) MX2010001583A (sl)
PL (1) PL2176430T3 (sl)
SI (1) SI2176430T1 (sl)
WO (1) WO2009021684A2 (sl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2969174B1 (fr) 2010-12-16 2014-03-14 Commissariat Energie Atomique Ligand specifique de la proteine lar

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5202231A (en) 1987-04-01 1993-04-13 Drmanac Radoje T Method of sequencing of genomes by hybridization of oligonucleotide probes
US5525464A (en) * 1987-04-01 1996-06-11 Hyseq, Inc. Method of sequencing by hybridization of oligonucleotide probes
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5744101A (en) * 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5795716A (en) * 1994-10-21 1998-08-18 Chee; Mark S. Computer-aided visualization and analysis system for sequence evaluation
AU2004211955B2 (en) * 2003-02-06 2009-05-14 Cedars-Sinai Medical Center Gene expression markers for response to EGFR inhibitor drugs
EP2226396A1 (en) * 2003-05-30 2010-09-08 Genomic Health, Inc. Gene expression markers for response to EGFR inhibitor drugs
GB0312451D0 (en) * 2003-05-30 2003-07-09 Astrazeneca Uk Ltd Process
NZ543234A (en) * 2003-05-30 2009-04-30 Astrazeneca Uk Ltd Marker genes and uses thereof to identify cancer patients that will respond to erbb tyrosine kinase inhibitors
US20060234237A1 (en) * 2004-01-08 2006-10-19 Amler Lukas C Biomarkers and methods for determining sensitivity to epidermal growth factor receptor modulators

Also Published As

Publication number Publication date
ES2395881T9 (es) 2013-09-06
DK2176430T5 (da) 2013-09-08
KR101169246B1 (ko) 2012-08-03
CA2695473A1 (en) 2009-02-19
US9121067B2 (en) 2015-09-01
IL203647A (en) 2013-02-28
AU2008286337B2 (en) 2011-10-27
US20110184005A1 (en) 2011-07-28
CA2695473C (en) 2013-10-01
DK2176430T3 (da) 2012-10-08
CN101827947A (zh) 2010-09-08
PL2176430T3 (pl) 2013-02-28
EP2176430A2 (en) 2010-04-21
WO2009021684A2 (en) 2009-02-19
BRPI0815543A2 (pt) 2013-03-12
US20130210843A1 (en) 2013-08-15
JP2010535524A (ja) 2010-11-25
EP2176430B1 (en) 2012-09-19
KR20100037634A (ko) 2010-04-09
ES2395881T3 (es) 2013-02-15
WO2009021684A3 (en) 2009-04-16
MX2010001583A (es) 2010-03-15
EP2176430B9 (en) 2013-07-24
AU2008286337A1 (en) 2009-02-19
CN101827947B (zh) 2013-11-13
JP5368445B2 (ja) 2013-12-18

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