JP2006520781A5 - - Google Patents
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- JP2006520781A5 JP2006520781A5 JP2006507006A JP2006507006A JP2006520781A5 JP 2006520781 A5 JP2006520781 A5 JP 2006520781A5 JP 2006507006 A JP2006507006 A JP 2006507006A JP 2006507006 A JP2006507006 A JP 2006507006A JP 2006520781 A5 JP2006520781 A5 JP 2006520781A5
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- JP
- Japan
- Prior art keywords
- seq
- composition
- cancer
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- fragment
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45367203P | 2003-03-10 | 2003-03-10 | |
| PCT/US2004/007198 WO2004081190A2 (en) | 2003-03-10 | 2004-03-09 | Uses of il-23 agonists and antagonists; related reagents |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007046287A Division JP2007197453A (ja) | 2003-03-10 | 2007-02-26 | Ｉｌ−２３アゴニストおよびｉｌ−２３アンタゴニスト；関連試薬の使用 |
| JP2010200382A Division JP2011032275A (ja) | 2003-03-10 | 2010-09-07 | Ｉｌ−２３アゴニストおよびｉｌ−２３アンタゴニスト；関連試薬の使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006520781A JP2006520781A (ja) | 2006-09-14 |
| JP2006520781A5 true JP2006520781A5 (https=) | 2007-04-12 |
| JP4605798B2 JP4605798B2 (ja) | 2011-01-05 |
Family
ID=32990805
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006507006A Expired - Fee Related JP4605798B2 (ja) | 2003-03-10 | 2004-03-09 | Ｉｌ−２３アゴニストおよびｉｌ−２３アンタゴニスト；関連試薬の使用 |
| JP2007046287A Pending JP2007197453A (ja) | 2003-03-10 | 2007-02-26 | Ｉｌ−２３アゴニストおよびｉｌ−２３アンタゴニスト；関連試薬の使用 |
| JP2010200382A Withdrawn JP2011032275A (ja) | 2003-03-10 | 2010-09-07 | Ｉｌ−２３アゴニストおよびｉｌ−２３アンタゴニスト；関連試薬の使用 |
| JP2013168870A Pending JP2014005286A (ja) | 2003-03-10 | 2013-08-15 | Ｉｌ−２３アゴニストおよびｉｌ−２３アンタゴニスト；関連試薬の使用 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007046287A Pending JP2007197453A (ja) | 2003-03-10 | 2007-02-26 | Ｉｌ−２３アゴニストおよびｉｌ−２３アンタゴニスト；関連試薬の使用 |
| JP2010200382A Withdrawn JP2011032275A (ja) | 2003-03-10 | 2010-09-07 | Ｉｌ−２３アゴニストおよびｉｌ−２３アンタゴニスト；関連試薬の使用 |
| JP2013168870A Pending JP2014005286A (ja) | 2003-03-10 | 2013-08-15 | Ｉｌ−２３アゴニストおよびｉｌ−２３アンタゴニスト；関連試薬の使用 |
Country Status (22)
| Country | Link |
|---|---|
| US (4) | US7282204B2 (https=) |
| EP (2) | EP2108658B1 (https=) |
| JP (4) | JP4605798B2 (https=) |
| CN (1) | CN1759123B (https=) |
| AT (1) | ATE440864T1 (https=) |
| AU (2) | AU2004219625B9 (https=) |
| BR (1) | BRPI0408247A (https=) |
| CA (1) | CA2518262C (https=) |
| CL (1) | CL2004000467A1 (https=) |
| CY (1) | CY1109468T1 (https=) |
| DE (1) | DE602004022781D1 (https=) |
| DK (1) | DK1601694T3 (https=) |
| ES (1) | ES2330220T3 (https=) |
| MX (1) | MXPA05009717A (https=) |
| NO (1) | NO20054630L (https=) |
| NZ (2) | NZ567860A (https=) |
| PL (1) | PL1601694T3 (https=) |
| PT (1) | PT1601694E (https=) |
| SI (1) | SI1601694T1 (https=) |
| TW (2) | TWI439285B (https=) |
| WO (1) | WO2004081190A2 (https=) |
| ZA (1) | ZA200506879B (https=) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020137890A1 (en) * | 1997-03-31 | 2002-09-26 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| WO2004042009A2 (en) * | 2002-10-30 | 2004-05-21 | Genentech, Inc. | Inhibition of il-17 production |
| US7282204B2 (en) * | 2003-03-10 | 2007-10-16 | Schering Corporation | Uses of IL-23 agonists and antagonists; related reagents |
| CN101052726A (zh) * | 2003-05-09 | 2007-10-10 | 森托科尔公司 | IL－23p40特异性免疫球蛋白衍生蛋白、组合物、方法和用途 |
| CN1942201B (zh) * | 2004-02-17 | 2012-06-20 | 先灵公司 | 调节il-23活性的方法；相关试剂 |
| US20060193821A1 (en) * | 2004-03-05 | 2006-08-31 | Diener John L | Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics |
| WO2005086835A2 (en) * | 2004-03-05 | 2005-09-22 | Archemix Corp. | Aptamers to the human il-12 cytokine family and their use as autoimmune disease therapeutics |
| AR051444A1 (es) * | 2004-09-24 | 2007-01-17 | Centocor Inc | Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos |
| US7820168B2 (en) | 2004-12-20 | 2010-10-26 | Schering Corporation | Treatment of diabetes using antibodies to IL-23, IL-23 receptor and IL-17 |
| CA2612785A1 (en) * | 2005-06-30 | 2007-01-11 | Archemix Corp. | Polynucleotides and polypeptides of the il-12 family of cytokines |
| SI2452694T1 (sl) | 2005-06-30 | 2019-05-31 | Janssen Biotech, Inc. | Protitelesa proti-IL-23, sestavki in postopki uporabe |
| AU2012258409B2 (en) * | 2005-06-30 | 2016-01-07 | Centocor, Inc. | Anti-IL-23 antibodies, compositions, methods and uses |
| DE602006015830D1 (de) * | 2005-08-25 | 2010-09-09 | Lilly Co Eli | Anti-il-23-antikörper |
| PT1931710T (pt) | 2005-08-31 | 2017-03-28 | Merck Sharp & Dohme | Anticorpos anti-il-23 manipulados |
| US20080199460A1 (en) | 2005-09-01 | 2008-08-21 | Schering Corporation | Use of IL-23 and IL-17 antagonists to treat autoimmune ocular inflammatory disease |
| HUE034269T2 (en) | 2005-12-29 | 2018-02-28 | Janssen Biotech Inc | Human anti-IL-23 antibodies, preparations, methods and applications |
| US7910703B2 (en) * | 2006-03-10 | 2011-03-22 | Zymogenetics, Inc. | Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use |
| US7790862B2 (en) | 2006-06-13 | 2010-09-07 | Zymogenetics, Inc. | IL-17 and IL-23 antagonists and methods of using the same |
| EP1882699A1 (en) * | 2006-07-27 | 2008-01-30 | Heinfried Radeke | Regulation of interleukin-23 |
| TWI426918B (zh) * | 2007-02-12 | 2014-02-21 | Merck Sharp & Dohme | Ｉｌ-２３拮抗劑於治療感染之用途 |
| ES2708988T3 (es) | 2007-02-23 | 2019-04-12 | Merck Sharp & Dohme | Anticuerpos anti-IL-23p19 obtenidos por ingeniería genética |
| JP2010518858A (ja) | 2007-02-23 | 2010-06-03 | シェーリング コーポレイション | 操作された抗−ｉｌ−２３ｐ１９抗体 |
| NZ579251A (en) | 2007-02-28 | 2012-06-29 | Schering Corp | Engineered anti-il-23r antibodies |
| CA2679400A1 (en) | 2007-02-28 | 2008-09-04 | Schering Corporation | Combination therapy for treatment of immune disorders |
| JP2011501941A (ja) * | 2007-07-06 | 2011-01-20 | バロリゼイション エイチエスジェイ， ソシエテ アン コマンディテ | Ｉｌ−２３レセプターのアンタゴニストおよびその使用 |
| AR068723A1 (es) * | 2007-10-05 | 2009-12-02 | Glaxo Group Ltd | Proteina que se une a antigenos que se une a il-23 humana y sus usos |
| US20100331545A1 (en) | 2007-10-24 | 2010-12-30 | Nippon Chemiphar Co., Ltd. | Regulator for signaling toll-like receptor, which comprises cathepsin inhibitor as active ingredient |
| RU2474588C2 (ru) | 2008-05-05 | 2013-02-10 | Новиммун Са | Перекрестно-реактивные антитела анти-il-17a/il-17f и способы их применения |
| US20110158992A1 (en) * | 2008-08-27 | 2011-06-30 | Schering Corporation | Engineered Anti-IL-23R Antibodies |
| WO2010036924A2 (en) * | 2008-09-25 | 2010-04-01 | The United States Of America, As Represented By The Secretary, Department Of Healthe And Human Serv. | Inflammatory genes and microrna-21 as biomarkers for colon cancer prognosis |
| DK2350316T3 (da) * | 2008-10-20 | 2014-05-05 | Valipharma | Fremgangsmåder og anvendelser der involverer genetiske aberrationer af nav3 og aberrerende ekspression af multiple gener |
| US20120128689A1 (en) * | 2009-04-01 | 2012-05-24 | Glaxo Group Limited | Anti-il-23 immunoglobulins |
| CN102458437B (zh) | 2009-05-05 | 2015-06-10 | 诺维莫尼公司 | 抗il-17f抗体及其使用方法 |
| EP2456787A4 (en) * | 2009-07-24 | 2013-01-30 | Univ Leland Stanford Junior | CYTOKIN COMPOSITIONS AND METHOD FOR THEIR USE |
| US20110086806A1 (en) * | 2009-10-09 | 2011-04-14 | Anaphore, Inc. | Polypeptides that Bind IL-23R |
| JO3244B1 (ar) | 2009-10-26 | 2018-03-08 | Amgen Inc | بروتينات ربط مستضادات il – 23 البشرية |
| US20110311527A1 (en) | 2010-06-16 | 2011-12-22 | Allergan, Inc. | IL23p19 ANTIBODY INHIBITOR FOR TREATING OCULAR AND OTHER CONDITIONS |
| MX2019000046A (es) | 2010-11-04 | 2023-10-05 | Boehringer Ingelheim Int | Anticuerpos anti-il-23. |
| USRE49026E1 (en) | 2011-06-14 | 2022-04-12 | Medical Diagnostic Laboratories, Llc | Polypeptides that bound to IL-23 receptor and inhibit binding of IL-23 and cell signaling thereof |
| US8946150B2 (en) | 2011-06-14 | 2015-02-03 | Medical Diagnostic Laboratories, LLC. | Polypeptides that bound to IL-23 receptor and inhibit binding of IL-23 and cell signaling thereof |
| PL3326649T3 (pl) | 2012-05-03 | 2022-04-25 | Boehringer Ingelheim International Gmbh | Przeciwciała anty-il-23p19 |
| ES2729603T3 (es) | 2012-06-27 | 2019-11-05 | Merck Sharp & Dohme | Anticuerpos IL-23 antihumanos cristalinos |
| UA117466C2 (uk) | 2012-12-13 | 2018-08-10 | Мерк Шарп Енд Доме Корп. | СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19 |
| AR094877A1 (es) | 2013-03-08 | 2015-09-02 | Lilly Co Eli | Anticuerpos que se unen a il-23 |
| EP3708679A1 (en) | 2014-07-24 | 2020-09-16 | Boehringer Ingelheim International GmbH | Biomarkers useful in the treatment of il-23a related diseases |
| EA202193002A2 (ru) | 2014-09-03 | 2022-03-31 | Бёрингер Ингельхайм Интернациональ Гмбх | Соединение, нацеленное на ил-23a и фно-альфа, и его применение |
| AR102417A1 (es) | 2014-11-05 | 2017-03-01 | Lilly Co Eli | Anticuerpos biespecíficos anti-tnf- / anti-il-23 |
| AU2016215535B2 (en) | 2015-02-04 | 2021-09-16 | Boehringer Ingelheim International Gmbh | Methods of treating inflammatory diseases |
| JP6871876B2 (ja) | 2015-03-11 | 2021-05-19 | ラッシュ ユニヴァーシティ メディカル センター | がんを治療するための組成物と方法 |
| JP7382232B2 (ja) | 2017-05-02 | 2023-11-16 | メルク・シャープ・アンド・ドーム・エルエルシー | 抗ｌａｇ３抗体の製剤および抗ｌａｇ３抗体と抗ｐｄ－１抗体との共製剤 |
| JOP20190260A1 (ar) | 2017-05-02 | 2019-10-31 | Merck Sharp & Dohme | صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها |
| MX2020009265A (es) | 2018-03-05 | 2020-10-01 | Janssen Biotech Inc | Metodos para tratar la enfermedad de crohn con un anticuerpo especifico anti-il23. |
| WO2020081408A1 (en) | 2018-10-18 | 2020-04-23 | Merck Sharp & Dohme Corp. | Formulations of anti-rsv antibodies and methods of use thereof |
| MX2021004928A (es) | 2018-10-31 | 2021-06-08 | Merck Sharp & Dohme Llc | Cristales de anticuerpo anti-pd-1 humano y metodos de uso de los mismos. |
| EP3876990A4 (en) | 2018-11-07 | 2023-09-06 | Merck Sharp & Dohme LLC | CO-FORMULATIONS OF ANTI-LAG3 ANTIBODIES AND ANTI-PD-1 ANTIBODIES |
| IL283192B2 (en) | 2018-11-20 | 2025-10-01 | Janssen Biotech Inc | A safe and effective method for treating psoriasis with a specific anti-IL-23 antibody |
| JP7805788B2 (ja) | 2019-05-23 | 2026-01-26 | ヤンセン バイオテツク，インコーポレーテツド | Ｉｌ－２３及びｔｎｆアルファに対する抗体の併用療法による炎症性腸疾患の治療方法 |
| TW202535466A (zh) | 2019-09-09 | 2025-09-16 | 德商百靈佳殷格翰國際股份有限公司 | 抗-il-23p19抗體調配物 |
| CN115916261A (zh) * | 2020-04-17 | 2023-04-04 | 小利兰·斯坦福大学董事会 | 工程化il-12和il-23多肽及其用途 |
| IL298389A (en) | 2020-05-21 | 2023-01-01 | Janssen Biotech Inc | Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha |
| CA3234552A1 (en) | 2021-10-20 | 2023-04-27 | Synthekine, Inc. | Heterodimeric fc cytokines and uses thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6176962B1 (en) | 1990-02-28 | 2001-01-23 | Aclara Biosciences, Inc. | Methods for fabricating enclosed microchannel structures |
| US5571702A (en) | 1991-03-29 | 1996-11-05 | Genentech, Inc. | Amplification method for detection of human PF4A receptors |
| US6132764A (en) | 1994-08-05 | 2000-10-17 | Targesome, Inc. | Targeted polymerized liposome diagnostic and treatment agents |
| WO1997003715A1 (en) | 1995-07-21 | 1997-02-06 | The General Hospital Corporation | Method and apparatus of enhancing the delivery of a pharmaceutical formulation |
| US6056973A (en) | 1996-10-11 | 2000-05-02 | Sequus Pharmaceuticals, Inc. | Therapeutic liposome composition and method of preparation |
| US6060284A (en) * | 1997-07-25 | 2000-05-09 | Schering Corporation | DNA encoding interleukin-B30 |
| US5842787A (en) | 1997-10-09 | 1998-12-01 | Caliper Technologies Corporation | Microfluidic systems incorporating varied channel dimensions |
| US6326482B1 (en) | 1999-04-23 | 2001-12-04 | Genentech, Inc. | SH2 domain-containing peptides |
| HK1044159A1 (zh) | 1998-12-01 | 2002-10-11 | 蛋白质设计实验室股份有限公司 | 抗γ-干扰素的人化抗体 |
| AU780163B2 (en) * | 1999-09-09 | 2005-03-03 | Merck Sharp & Dohme Corp. | Mammalian interleukin-12 P40 and interleukin B30, combinations thereof, antibodies, uses in pharmaceutical compositions |
| US6756481B2 (en) * | 2000-05-10 | 2004-06-29 | Schering Corporation | IL-23 receptor binding compositions |
| AU2002223182B2 (en) * | 2000-10-06 | 2007-08-30 | Immunex Corporation | Hematopoietin receptors HPR1 and HPR2 |
| AU2002314825A1 (en) * | 2001-05-30 | 2002-12-09 | Centocor, Inc. | Anti-p40 immunoglobulin derived proteins, compositions, methods and uses |
| US7282204B2 (en) * | 2003-03-10 | 2007-10-16 | Schering Corporation | Uses of IL-23 agonists and antagonists; related reagents |
-
2004
- 2004-03-09 US US10/797,157 patent/US7282204B2/en not_active Expired - Lifetime
- 2004-03-09 EP EP09163834.6A patent/EP2108658B1/en not_active Expired - Lifetime
- 2004-03-09 DK DK04718824T patent/DK1601694T3/da active
- 2004-03-09 CN CN2004800067148A patent/CN1759123B/zh not_active Expired - Fee Related
- 2004-03-09 PL PL04718824T patent/PL1601694T3/pl unknown
- 2004-03-09 TW TW100126443A patent/TWI439285B/zh not_active IP Right Cessation
- 2004-03-09 CA CA2518262A patent/CA2518262C/en not_active Expired - Fee Related
- 2004-03-09 AT AT04718824T patent/ATE440864T1/de active
- 2004-03-09 SI SI200431281T patent/SI1601694T1/sl unknown
- 2004-03-09 NZ NZ567860A patent/NZ567860A/en not_active IP Right Cessation
- 2004-03-09 AU AU2004219625A patent/AU2004219625B9/en not_active Ceased
- 2004-03-09 JP JP2006507006A patent/JP4605798B2/ja not_active Expired - Fee Related
- 2004-03-09 NZ NZ541898A patent/NZ541898A/en not_active IP Right Cessation
- 2004-03-09 TW TW093106213A patent/TWI357336B/zh not_active IP Right Cessation
- 2004-03-09 MX MXPA05009717A patent/MXPA05009717A/es active IP Right Grant
- 2004-03-09 CL CL200400467A patent/CL2004000467A1/es unknown
- 2004-03-09 WO PCT/US2004/007198 patent/WO2004081190A2/en not_active Ceased
- 2004-03-09 DE DE602004022781T patent/DE602004022781D1/de not_active Expired - Lifetime
- 2004-03-09 ES ES04718824T patent/ES2330220T3/es not_active Expired - Lifetime
- 2004-03-09 EP EP04718824A patent/EP1601694B1/en not_active Expired - Lifetime
- 2004-03-09 PT PT04718824T patent/PT1601694E/pt unknown
- 2004-03-09 BR BRPI0408247-8A patent/BRPI0408247A/pt not_active IP Right Cessation
-
2005
- 2005-08-26 ZA ZA200506879A patent/ZA200506879B/en unknown
- 2005-10-07 NO NO20054630A patent/NO20054630L/no not_active Application Discontinuation
-
2007
- 2007-02-26 JP JP2007046287A patent/JP2007197453A/ja active Pending
- 2007-08-31 US US11/848,462 patent/US20080057058A1/en not_active Abandoned
-
2009
- 2009-08-24 US US12/546,230 patent/US8034341B2/en not_active Expired - Lifetime
- 2009-10-06 CY CY20091101030T patent/CY1109468T1/el unknown
-
2010
- 2010-08-16 AU AU2010212372A patent/AU2010212372B2/en not_active Ceased
- 2010-09-07 JP JP2010200382A patent/JP2011032275A/ja not_active Withdrawn
-
2011
- 2011-10-10 US US13/270,077 patent/US20120034219A1/en not_active Abandoned
-
2013
- 2013-08-15 JP JP2013168870A patent/JP2014005286A/ja active Pending
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