JP2006519906A5 - - Google Patents
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- Publication number
- JP2006519906A5 JP2006519906A5 JP2006506297A JP2006506297A JP2006519906A5 JP 2006519906 A5 JP2006519906 A5 JP 2006519906A5 JP 2006506297 A JP2006506297 A JP 2006506297A JP 2006506297 A JP2006506297 A JP 2006506297A JP 2006519906 A5 JP2006519906 A5 JP 2006519906A5
- Authority
- JP
- Japan
- Prior art keywords
- heparin
- drum dryer
- salt
- solid form
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45270103P | 2003-03-07 | 2003-03-07 | |
| PCT/IB2004/000625 WO2004078791A1 (en) | 2003-03-07 | 2004-03-04 | Method to produce a solid form of heparin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006519906A JP2006519906A (ja) | 2006-08-31 |
| JP2006519906A5 true JP2006519906A5 (https=) | 2011-02-24 |
Family
ID=32962743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006506297A Ceased JP2006519906A (ja) | 2003-03-07 | 2004-03-04 | ヘパリンの固体形態の製造方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6933372B2 (https=) |
| EP (1) | EP1611161B1 (https=) |
| JP (1) | JP2006519906A (https=) |
| AR (1) | AR043731A1 (https=) |
| AT (1) | ATE368057T1 (https=) |
| CA (1) | CA2517141C (https=) |
| CL (1) | CL2004000414A1 (https=) |
| DE (1) | DE602004007784T2 (https=) |
| ES (1) | ES2289492T3 (https=) |
| MX (1) | MXPA05009498A (https=) |
| TW (1) | TWI274761B (https=) |
| WO (1) | WO2004078791A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0327723D0 (en) * | 2003-09-15 | 2003-12-31 | Vectura Ltd | Pharmaceutical compositions |
| CN101575385B (zh) * | 2008-05-09 | 2011-01-12 | 青岛九龙生物医药有限公司 | 萃取法分离肝素钠中的多硫酸软骨素的方法 |
| CN101831008B (zh) * | 2009-03-11 | 2013-04-10 | 四川茂森生物科技有限公司 | 粗品肝素钠精制生产新工艺 |
| CN108508129B (zh) * | 2018-04-03 | 2020-11-27 | 青岛海洋生物医药研究院股份有限公司 | 一种肝素类药物生物效价的测定方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2034599A (en) * | 1933-07-10 | 1936-03-17 | Buffalo Foundry & Machine Co | Method of drying inorganic salts and sludges |
| US2571679A (en) * | 1948-07-08 | 1951-10-16 | Carlo Erba S A | Process for preparing purified heparin |
| US2797184A (en) * | 1953-07-01 | 1957-06-25 | Upjohn Co | Process for the recovery of heparin |
| US2884358A (en) * | 1957-04-22 | 1959-04-28 | Southern California Gland Co | Process for preparing crude heparin |
| US2954321A (en) * | 1957-09-23 | 1960-09-27 | Upjohn Co | Process for preparing heparin |
| US3337409A (en) * | 1963-11-20 | 1967-08-22 | Rexall Drug Chemical | Process for the recovery of heparin |
| US3330327A (en) * | 1964-03-30 | 1967-07-11 | Continental Oil Co | Drying tertiary amine oxides on extended heated surfaces at elevated temperatures |
| US3817831A (en) * | 1973-01-10 | 1974-06-18 | Wilson Pharm & Chem Corp | Process for production of alkali metal salt of heparin |
| CA1136620A (en) | 1979-01-08 | 1982-11-30 | Ulf P.F. Lindahl | Heparin fragments having selective anticoagulation activity |
| US4510135A (en) * | 1982-04-21 | 1985-04-09 | Research Corporation | Orally administered heparin |
| DE3422518A1 (de) * | 1984-06-16 | 1985-12-19 | B. Braun Melsungen Ag, 3508 Melsungen | Heparin-derivate, verfahren zu ihrer herstellung, diese enthaltende arzneimittel und ihre verwendung bei der behandlung von fettstoffwechselstoerungen |
| DK170015B1 (da) * | 1992-03-19 | 1995-05-01 | Sudurnesja Hitaveita | Saltprodukt samt fremgangsmåde til dets fremstilling |
| US5668118A (en) | 1992-07-24 | 1997-09-16 | Cavalier Pharmaceuticals | Method of synthesis of 2-O-desulfated Heparin and use thereof for inhibition of elastase and Cathepspin G |
| DE4310088A1 (de) * | 1993-03-27 | 1994-09-29 | Hoechst Ag | Verfahren zur Herstellung und Aufarbeitung von in wäßrigem Medium löslichen N-Hydroxyalkylchitosanen |
| CA2160440C (en) | 1994-10-13 | 1998-08-25 | Louis G. Lange, Iii | Method of manufacturing non-absorbable synthetic sulfated polysaccharides |
| CA2173642C (en) | 1995-04-10 | 1999-11-02 | James Vincent Gruber | Process for derivatizing polyglucosamines |
| BR9810881B1 (pt) * | 1997-07-16 | 2009-01-13 | mÉtodo para produzir heparina a partir do tecido da mucosa de mamÍferos. | |
| CN1218058A (zh) | 1997-11-26 | 1999-06-02 | 中国林业科学研究院林产化学工业研究所 | 肝素的喷雾干燥方法 |
| US6485945B1 (en) * | 1999-02-17 | 2002-11-26 | Nurture, Inc. | Polysaccharide compositions and uses thereof |
| WO2001057092A1 (en) | 2000-02-07 | 2001-08-09 | Granate Seed Limited | PROCESS FOR EXTRACTION OF β-GLUCAN FROM CEREALS AND PRODUCTS OBTAINED THEREFROM |
-
2004
- 2004-02-27 US US10/789,466 patent/US6933372B2/en not_active Expired - Fee Related
- 2004-03-02 CL CL200400414A patent/CL2004000414A1/es unknown
- 2004-03-04 MX MXPA05009498A patent/MXPA05009498A/es active IP Right Grant
- 2004-03-04 EP EP04717174A patent/EP1611161B1/en not_active Expired - Lifetime
- 2004-03-04 CA CA002517141A patent/CA2517141C/en not_active Expired - Fee Related
- 2004-03-04 DE DE602004007784T patent/DE602004007784T2/de not_active Expired - Lifetime
- 2004-03-04 AT AT04717174T patent/ATE368057T1/de not_active IP Right Cessation
- 2004-03-04 JP JP2006506297A patent/JP2006519906A/ja not_active Ceased
- 2004-03-04 WO PCT/IB2004/000625 patent/WO2004078791A1/en not_active Ceased
- 2004-03-04 ES ES04717174T patent/ES2289492T3/es not_active Expired - Lifetime
- 2004-03-05 TW TW093105873A patent/TWI274761B/zh not_active IP Right Cessation
- 2004-03-05 AR ARP040100707A patent/AR043731A1/es active IP Right Grant
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