JP2006518604A5 - - Google Patents
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- Publication number
- JP2006518604A5 JP2006518604A5 JP2006503825A JP2006503825A JP2006518604A5 JP 2006518604 A5 JP2006518604 A5 JP 2006518604A5 JP 2006503825 A JP2006503825 A JP 2006503825A JP 2006503825 A JP2006503825 A JP 2006503825A JP 2006518604 A5 JP2006518604 A5 JP 2006518604A5
- Authority
- JP
- Japan
- Prior art keywords
- prtp801
- plasmid
- vegf
- pharmaceutical composition
- growth factor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 15
- 239000013612 plasmid Substances 0.000 claims 14
- 210000004027 cell Anatomy 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 108010073929 Vascular Endothelial Growth Factor A Proteins 0.000 claims 7
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims 6
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims 6
- 206010021143 Hypoxia Diseases 0.000 claims 4
- 238000001476 gene delivery Methods 0.000 claims 4
- 230000007954 hypoxia Effects 0.000 claims 4
- 208000023589 ischemic disease Diseases 0.000 claims 4
- 210000004413 cardiac myocyte Anatomy 0.000 claims 3
- 208000031225 myocardial ischemia Diseases 0.000 claims 3
- 230000007959 normoxia Effects 0.000 claims 2
- 102000009524 Vascular Endothelial Growth Factor A Human genes 0.000 claims 1
- 239000000969 carrier Substances 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44896103P | 2003-02-21 | 2003-02-21 | |
| PCT/US2004/005372 WO2004076633A2 (en) | 2003-02-21 | 2004-02-23 | Hypoxia inducible vegf plasmid for ischemic disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006518604A JP2006518604A (ja) | 2006-08-17 |
| JP2006518604A5 true JP2006518604A5 (enExample) | 2007-04-05 |
| JP4652325B2 JP4652325B2 (ja) | 2011-03-16 |
Family
ID=32927484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006503825A Expired - Fee Related JP4652325B2 (ja) | 2003-02-21 | 2004-02-23 | 虚血性疾患用の低酸素状態誘導可能ｖｅｇｆプラスミド |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7638322B2 (enExample) |
| EP (1) | EP1594549B1 (enExample) |
| JP (1) | JP4652325B2 (enExample) |
| KR (1) | KR101077689B1 (enExample) |
| AT (1) | ATE456380T1 (enExample) |
| CA (1) | CA2516727C (enExample) |
| DE (1) | DE602004025328D1 (enExample) |
| ES (1) | ES2339113T3 (enExample) |
| WO (1) | WO2004076633A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101094617B1 (ko) | 2004-08-16 | 2011-12-15 | 사일런스 테라퓨틱스 아게 | 알티피801 억제제의 치료적 용도 |
| DOP2007000015A (es) | 2006-01-20 | 2007-08-31 | Quark Biotech Inc | Usos terapéuticos de inhibidores de rtp801 |
| GB2450840B (en) * | 2006-05-11 | 2010-12-29 | Quark Pharmaceuticals Inc | Screening Systems Utilizing RTP801 |
| WO2007141796A2 (en) | 2006-06-09 | 2007-12-13 | Quark Pharmaceuticals, Inc. | Therapeutic uses of inhibitors of rtp801l |
| JP2010518880A (ja) | 2007-02-26 | 2010-06-03 | クアーク・ファーマスーティカルス、インコーポレイテッド | Ｒｔｐ８０１のインヒビター及びその疾患の治療における使用 |
| US8614311B2 (en) | 2007-12-12 | 2013-12-24 | Quark Pharmaceuticals, Inc. | RTP801L siRNA compounds and methods of use thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030104973A1 (en) * | 1997-08-21 | 2003-06-05 | Quark Biotech, Inc. | Hypoxia-regulated genes |
| US6548633B1 (en) * | 1998-12-22 | 2003-04-15 | Genset, S.A. | Complementary DNA's encoding proteins with signal peptides |
-
2004
- 2004-02-23 WO PCT/US2004/005372 patent/WO2004076633A2/en not_active Ceased
- 2004-02-23 AT AT04713771T patent/ATE456380T1/de not_active IP Right Cessation
- 2004-02-23 KR KR1020057015480A patent/KR101077689B1/ko not_active Expired - Fee Related
- 2004-02-23 CA CA2516727A patent/CA2516727C/en not_active Expired - Fee Related
- 2004-02-23 EP EP04713771A patent/EP1594549B1/en not_active Expired - Lifetime
- 2004-02-23 ES ES04713771T patent/ES2339113T3/es not_active Expired - Lifetime
- 2004-02-23 US US10/546,115 patent/US7638322B2/en not_active Expired - Fee Related
- 2004-02-23 JP JP2006503825A patent/JP4652325B2/ja not_active Expired - Fee Related
- 2004-02-23 DE DE602004025328T patent/DE602004025328D1/de not_active Expired - Lifetime
-
2009
- 2009-12-29 US US12/649,141 patent/US7998941B2/en not_active Expired - Fee Related
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