JP2005521632A5 - - Google Patents
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- Publication number
- JP2005521632A5 JP2005521632A5 JP2003512371A JP2003512371A JP2005521632A5 JP 2005521632 A5 JP2005521632 A5 JP 2005521632A5 JP 2003512371 A JP2003512371 A JP 2003512371A JP 2003512371 A JP2003512371 A JP 2003512371A JP 2005521632 A5 JP2005521632 A5 JP 2005521632A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- nucleic acid
- patient
- foreign nucleic
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 210000004027 cell Anatomy 0.000 claims 39
- 238000000034 method Methods 0.000 claims 36
- 150000007523 nucleic acids Chemical class 0.000 claims 26
- 108020004707 nucleic acids Proteins 0.000 claims 24
- 102000039446 nucleic acids Human genes 0.000 claims 24
- 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 claims 14
- 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 claims 14
- 210000000777 hematopoietic system Anatomy 0.000 claims 12
- 230000037396 body weight Effects 0.000 claims 8
- 210000004976 peripheral blood cell Anatomy 0.000 claims 8
- 230000036436 anti-hiv Effects 0.000 claims 6
- 238000001574 biopsy Methods 0.000 claims 6
- 108090000994 Catalytic RNA Proteins 0.000 claims 5
- 102000053642 Catalytic RNA Human genes 0.000 claims 5
- 108091092562 ribozyme Proteins 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 230000000840 anti-viral effect Effects 0.000 claims 3
- 210000001185 bone marrow Anatomy 0.000 claims 3
- 210000002798 bone marrow cell Anatomy 0.000 claims 3
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 2
- 210000005105 peripheral blood lymphocyte Anatomy 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 238000011529 RT qPCR Methods 0.000 claims 1
- 230000000692 anti-sense effect Effects 0.000 claims 1
- 238000002617 apheresis Methods 0.000 claims 1
- 238000010322 bone marrow transplantation Methods 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 238000001415 gene therapy Methods 0.000 claims 1
- 230000003394 haemopoietic effect Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 230000003834 intracellular effect Effects 0.000 claims 1
- 210000004698 lymphocyte Anatomy 0.000 claims 1
- 238000002271 resection Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30428301P | 2001-07-10 | 2001-07-10 | |
| US34339201P | 2001-10-22 | 2001-10-22 | |
| PCT/US2002/021713 WO2003006612A2 (en) | 2001-07-10 | 2002-07-10 | Production of transduced hematopoietic progenitor cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005521632A JP2005521632A (ja) | 2005-07-21 |
| JP2005521632A5 true JP2005521632A5 (enExample) | 2006-01-05 |
Family
ID=26973926
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003512371A Withdrawn JP2005521632A (ja) | 2001-07-10 | 2002-07-10 | 形質導入造血前駆細胞の生産 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20030082158A1 (enExample) |
| EP (1) | EP1418814A4 (enExample) |
| JP (1) | JP2005521632A (enExample) |
| KR (1) | KR20040084885A (enExample) |
| CN (1) | CN1551728A (enExample) |
| BR (1) | BR0211066A (enExample) |
| CA (1) | CA2453187A1 (enExample) |
| IL (1) | IL159777A0 (enExample) |
| WO (1) | WO2003006612A2 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020058636A1 (en) * | 1994-09-21 | 2002-05-16 | Geoffrey P. Symonds | Ribozymes targeting the retroviral packaging sequence expression constructs and recombinant retroviruses containing such constructs |
| ES2358187T3 (es) * | 2001-07-10 | 2011-05-06 | JOHNSON & JOHNSON RESEARCH PTY LIMITED | Procedimientos para la modificación genética de las células progenitoras hematopoyéticas y utilizaciones de las células modificadas. |
| CA2453531A1 (en) * | 2001-07-10 | 2003-01-23 | Johnson & Johnson Research Pty Limited | Methods for genetic modification of hematopoietic progenitor cells and uses of the modified cells |
| EP2292734A1 (en) * | 2001-12-07 | 2011-03-09 | Geron Corporation | Hematopoietic cells from human embryonic stem cells |
| US7799324B2 (en) | 2001-12-07 | 2010-09-21 | Geron Corporation | Using undifferentiated embryonic stem cells to control the immune system |
| WO2004041220A2 (en) * | 2002-11-06 | 2004-05-21 | L'oreal | Composition containing a semi-crystalline polymer and a pasty fatty substance |
| FR2846554B1 (fr) * | 2002-11-06 | 2007-02-09 | Oreal | Composition contenant un polymere semi-cristallin et un corps gras pateux |
| GB0410130D0 (en) * | 2004-05-06 | 2004-06-09 | Molmed Spa | Cell preparation |
| JP5946775B2 (ja) | 2010-12-01 | 2016-07-06 | 日産化学工業株式会社 | ピラゾール化合物による造血幹細胞の製造方法 |
| US11697799B2 (en) | 2019-04-15 | 2023-07-11 | Ossium Health, Inc. | System and method for extraction and cryopreservation of bone marrow |
| EP4181675A4 (en) | 2020-07-18 | 2024-04-24 | Ossium Health, Inc. | PERMEATION OF WHOLE VERTEBRATE BODIES WITH A CRYOPRETECTIVE AGENT USING VACUUM-ASSISTED DIFFUSION |
| CN116583594B (zh) | 2020-10-14 | 2025-05-23 | 奥瑟姆健康公司 | 用于骨髓的提取和低温保藏的系统和方法 |
| WO2022133282A1 (en) | 2020-12-18 | 2022-06-23 | Ossium Health, Inc. | Methods of cell therapies |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5500357A (en) * | 1990-11-02 | 1996-03-19 | Agency Of Industrial Science & Technology, Ministry Of International Trade & Industry | RNA transcription system using novel ribozyme |
| US5525468A (en) * | 1992-05-14 | 1996-06-11 | Ribozyme Pharmaceuticals, Inc. | Assay for Ribozyme target site |
| US5693535A (en) * | 1992-05-14 | 1997-12-02 | Ribozyme Pharmaceuticals, Inc. | HIV targeted ribozymes |
| US5911983A (en) * | 1992-06-26 | 1999-06-15 | University Of Pittsburgh | Gene therapy for Gaucher disease using retroviral vectors |
| US5712384A (en) * | 1994-01-05 | 1998-01-27 | Gene Shears Pty Ltd. | Ribozymes targeting retroviral packaging sequence expression constructs and recombinant retroviruses containing such constructs |
| US20020058636A1 (en) * | 1994-09-21 | 2002-05-16 | Geoffrey P. Symonds | Ribozymes targeting the retroviral packaging sequence expression constructs and recombinant retroviruses containing such constructs |
| ES2358187T3 (es) * | 2001-07-10 | 2011-05-06 | JOHNSON & JOHNSON RESEARCH PTY LIMITED | Procedimientos para la modificación genética de las células progenitoras hematopoyéticas y utilizaciones de las células modificadas. |
| CA2453531A1 (en) * | 2001-07-10 | 2003-01-23 | Johnson & Johnson Research Pty Limited | Methods for genetic modification of hematopoietic progenitor cells and uses of the modified cells |
-
2002
- 2002-07-10 KR KR10-2004-7000432A patent/KR20040084885A/ko not_active Withdrawn
- 2002-07-10 IL IL15977702A patent/IL159777A0/xx unknown
- 2002-07-10 CN CNA028174879A patent/CN1551728A/zh active Pending
- 2002-07-10 JP JP2003512371A patent/JP2005521632A/ja not_active Withdrawn
- 2002-07-10 CA CA002453187A patent/CA2453187A1/en not_active Abandoned
- 2002-07-10 US US10/192,058 patent/US20030082158A1/en not_active Abandoned
- 2002-07-10 EP EP02749878A patent/EP1418814A4/en not_active Withdrawn
- 2002-07-10 WO PCT/US2002/021713 patent/WO2003006612A2/en not_active Ceased
- 2002-07-10 BR BRPI0211066-0A patent/BR0211066A/pt not_active IP Right Cessation
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