JP2006518333A5 - - Google Patents

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Publication number
JP2006518333A5
JP2006518333A5 JP2004563931A JP2004563931A JP2006518333A5 JP 2006518333 A5 JP2006518333 A5 JP 2006518333A5 JP 2004563931 A JP2004563931 A JP 2004563931A JP 2004563931 A JP2004563931 A JP 2004563931A JP 2006518333 A5 JP2006518333 A5 JP 2006518333A5
Authority
JP
Japan
Prior art keywords
propyl
tetrahydro
oxadiazol
butanoic acid
naphthyridin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2004563931A
Other languages
English (en)
Japanese (ja)
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JP2006518333A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/040898 external-priority patent/WO2004058254A1/en
Publication of JP2006518333A publication Critical patent/JP2006518333A/ja
Publication of JP2006518333A5 publication Critical patent/JP2006518333A5/ja
Withdrawn legal-status Critical Current

Links

JP2004563931A 2002-12-20 2003-12-22 インテグリン受容体アンタゴニストとしてのヘテロアリールアルカン酸 Withdrawn JP2006518333A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43546702P 2002-12-20 2002-12-20
PCT/US2003/040898 WO2004058254A1 (en) 2002-12-20 2003-12-22 Heteroarylalkanoic acids as integrin receptor antagonists

Publications (2)

Publication Number Publication Date
JP2006518333A JP2006518333A (ja) 2006-08-10
JP2006518333A5 true JP2006518333A5 (https=) 2007-02-01

Family

ID=32682246

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004563931A Withdrawn JP2006518333A (ja) 2002-12-20 2003-12-22 インテグリン受容体アンタゴニストとしてのヘテロアリールアルカン酸

Country Status (8)

Country Link
US (1) US20050043344A1 (https=)
EP (1) EP1592421A1 (https=)
JP (1) JP2006518333A (https=)
AU (1) AU2003299807A1 (https=)
BR (1) BR0317600A (https=)
CA (1) CA2507699A1 (https=)
MX (1) MXPA05006727A (https=)
WO (1) WO2004058254A1 (https=)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070011458A (ko) 2004-04-08 2007-01-24 탈자진 인코포레이티드 키나제의 벤조트리아진 억제제
PL382308A1 (pl) 2004-08-25 2007-08-20 Targegen, Inc. Związki heterocykliczne i sposoby stosowania
US8604042B2 (en) 2005-11-01 2013-12-10 Targegen, Inc. Bi-aryl meta-pyrimidine inhibitors of kinases
CN103626742B (zh) 2005-11-01 2017-04-26 塔格根公司 激酶的联-芳基间-嘧啶抑制剂
US8133900B2 (en) 2005-11-01 2012-03-13 Targegen, Inc. Use of bi-aryl meta-pyrimidine inhibitors of kinases
AU2006332694A1 (en) * 2005-12-30 2007-07-12 Alantos Pharmaceuticals, Holding, Inc. Substituted bis-amide metalloprotease inhibitors
US20080306116A1 (en) * 2007-06-08 2008-12-11 Christ Andreas D Aryloxazole, aryloxadiazole and benzimidazole derivatives
ES2457822T3 (es) * 2007-11-08 2014-04-29 The General Hospital Corporation Procedimientos y composiciones de tratamiento de enfermedades proteinúricas
PT2544679T (pt) 2010-03-12 2019-07-11 Omeros Corp Inibidores de pde-10 e composições e métodos relacionados
US9133123B2 (en) 2010-04-23 2015-09-15 Cytokinetics, Inc. Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use
AR081626A1 (es) 2010-04-23 2012-10-10 Cytokinetics Inc Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos
AR081331A1 (es) 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
CA2816957A1 (en) 2010-11-07 2012-05-10 Targegen, Inc. Compositions and methods for treating myelofibrosis
US8759380B2 (en) 2011-04-22 2014-06-24 Cytokinetics, Inc. Certain heterocycles, compositions thereof, and methods for their use
CN102381961B (zh) * 2011-09-03 2014-01-15 四川大学 3-苯基戊二酸类化合物、其制备方法和用途
US8901144B2 (en) 2013-02-07 2014-12-02 Scifluor Life Sciences, Llc Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives
HRP20171873T1 (hr) 2013-02-07 2018-02-23 Scifluor Life Sciences, Inc Fluorinirani antagonisti integrina
GB201305668D0 (en) 2013-03-28 2013-05-15 Glaxosmithkline Ip Dev Ltd Avs6 Integrin Antagonists
PL3050878T3 (pl) 2013-09-24 2022-01-24 Fujifilm Corporation Zawierający atom azotu związek lub jego sól, lub ich kompleks z metalem
NZ630803A (en) 2014-04-28 2016-03-31 Omeros Corp Optically active pde10 inhibitor
NZ716494A (en) 2014-04-28 2017-07-28 Omeros Corp Processes and intermediates for the preparation of a pde10 inhibitor
GB201417002D0 (en) 2014-09-26 2014-11-12 Glaxosmithkline Ip Dev Ltd Novel compound
GB201417018D0 (en) 2014-09-26 2014-11-12 Glaxosmithkline Ip Dev Ltd Novel compounds
GB201417094D0 (en) 2014-09-26 2014-11-12 Glaxosmithkline Ip Dev Ltd Novel compounds
GB201417011D0 (en) 2014-09-26 2014-11-12 Glaxosmithkline Ip Dev Ltd Novel compounds
KR102647026B1 (ko) 2015-02-19 2024-03-12 사이플루어 라이프 사이언시즈, 인크 플루오르화 테트라히드로나프티리디닐 노난산 유도체 및 이의 용도
US9879002B2 (en) 2015-04-24 2018-01-30 Omeros Corporation PDE10 inhibitors and related compositions and methods
US9920045B2 (en) 2015-11-04 2018-03-20 Omeros Corporation Solid state forms of a PDE10 inhibitor
GB201604680D0 (en) 2016-03-21 2016-05-04 Glaxosmithkline Ip Dev Ltd Chemical Compounds
WO2018089353A1 (en) 2016-11-08 2018-05-17 Bristol-Myers Squibb Company 3-substituted propionic acids as alpha v integrin inhibitors
CN110177787A (zh) * 2016-12-29 2019-08-27 圣路易斯大学 整合素拮抗剂
ES2904645T3 (es) * 2017-11-07 2022-04-05 Bristol Myers Squibb Co Derivados de pirrolopirazina como inhibidores de integrina alfa v
CN115872926A (zh) * 2021-09-26 2023-03-31 南通诺泰生物医药技术有限公司 三唑类抗真菌药及其中间体的制备方法

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US5849736A (en) * 1993-11-24 1998-12-15 The Dupont Merck Pharmaceutical Company Isoxazoline and isoxazole fibrinogen receptor antagonists
US5700823A (en) * 1994-01-07 1997-12-23 Sugen, Inc. Treatment of platelet derived growth factor related disorders such as cancers
PT889877E (pt) * 1996-03-29 2002-02-28 Searle & Co Derivados fenileno meta substituidos e sua utilizacao como antagonitas ou inibidores integrina alfa v beta3
DE69713582T2 (de) * 1996-03-29 2003-01-09 G.D. Searle & Co., Chicago Zimtsäurederivate und deren verwendung als integrin-antagonisten
DE19620041A1 (de) * 1996-05-17 1998-01-29 Merck Patent Gmbh Adhäsionsrezeptor-Antagonisten
EP1049693A1 (en) * 1997-11-26 2000-11-08 Du Pont Pharmaceuticals Company 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS $g(a) v?$g(b) 3? ANTAGONISTS
JP2004511434A (ja) * 2000-06-15 2004-04-15 ファルマシア・コーポレーション インテグリン受容体アンタゴニストとしてのヘテロアリールアルカン酸
CA2443332A1 (en) * 2001-04-04 2002-10-17 University Of Rochester .alpha..nu..beta.3 integrin-binding polypeptide monobodies and their use
US6750215B2 (en) * 2001-08-08 2004-06-15 Pharmacia & Upjohn, S.P.A. Substituted benzoxazines as integrin antagonists

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