JP2006518184A - 弱毒寄生虫生ワクチン - Google Patents

弱毒寄生虫生ワクチン Download PDF

Info

Publication number
JP2006518184A
JP2006518184A JP2004537149A JP2004537149A JP2006518184A JP 2006518184 A JP2006518184 A JP 2006518184A JP 2004537149 A JP2004537149 A JP 2004537149A JP 2004537149 A JP2004537149 A JP 2004537149A JP 2006518184 A JP2006518184 A JP 2006518184A
Authority
JP
Japan
Prior art keywords
parasite
live attenuated
gene
protein
genus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004537149A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006518184A5 (enExample
Inventor
フアン・ポツペル・ニコール,フランシスカ・ヨハンナ
フエルメーレン,アーノルドウス・ニコラース
シユハープ,テオドルス・コーネリス
Original Assignee
アクゾ・ノベル・エヌ・ベー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アクゾ・ノベル・エヌ・ベー filed Critical アクゾ・ノベル・エヌ・ベー
Publication of JP2006518184A publication Critical patent/JP2006518184A/ja
Publication of JP2006518184A5 publication Critical patent/JP2006518184A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245Escherichia (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43595Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/635Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2004537149A 2002-09-20 2003-09-19 弱毒寄生虫生ワクチン Pending JP2006518184A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02078953 2002-09-20
PCT/EP2003/010696 WO2004026903A2 (en) 2002-09-20 2003-09-19 Live antenuated parasite vaccine

Publications (2)

Publication Number Publication Date
JP2006518184A true JP2006518184A (ja) 2006-08-10
JP2006518184A5 JP2006518184A5 (enExample) 2009-11-12

Family

ID=32011015

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004537149A Pending JP2006518184A (ja) 2002-09-20 2003-09-19 弱毒寄生虫生ワクチン

Country Status (8)

Country Link
US (1) US20050244437A1 (enExample)
EP (1) EP1543028A2 (enExample)
JP (1) JP2006518184A (enExample)
CN (1) CN100393866C (enExample)
AU (1) AU2003270274B2 (enExample)
BR (1) BR0313994A (enExample)
CA (1) CA2498604A1 (enExample)
WO (1) WO2004026903A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019156751A (ja) * 2018-03-13 2019-09-19 共立製薬株式会社 反芻動物のネオスポラ感染症に対するワクチン製剤

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004309380B2 (en) 2003-12-19 2010-04-29 Seattle Biomedical Research Institute Live genetically attenuated malaria vaccine
US7722860B2 (en) 2004-12-03 2010-05-25 Seattle Biomedical Research Institute Live genetically engineered protozoan vaccine
ES2319242B1 (es) 2005-12-23 2009-12-01 Laboratorios Hipra, S.A. Aislado avirulento de neospora canimum y sus usos.
US9265818B2 (en) * 2007-05-04 2016-02-23 The United States Of America, As Represented By The Secretary Of Agriculture Genetically modified Babesia parasites expressing protective tick antigens and uses thereof
ES2326770B1 (es) 2007-07-13 2010-07-26 Universidad Complutense De Madrid Uso de un nuevo aislado de neospora caninum para el desarrollo de pruebas de diagnostico y para la fabricacion de productos para el tratamiento y prevencion de la infenccion causada por neospora.
RU2525587C2 (ru) * 2008-05-29 2014-08-20 Интервет Интернэшнл Б.В. Вакцинная композиция для иммунизации животного против кокцидиоза и способ ее использования
MX2011005133A (es) * 2008-11-13 2011-08-04 Intervet Int Bv Vacuna contra eimeria para pavos.
CN102483413A (zh) * 2009-07-13 2012-05-30 热体实验室有限公司 使用核糖体蛋白提取物(rpe)的寄生虫病如利什曼病的诊断
EP2412382A1 (en) 2010-07-29 2012-02-01 University Court of the University of Edinburgh Recombinant Trypanosoma theileri parasite
US20130224249A1 (en) * 2010-09-03 2013-08-29 Ludwig Institute For Cancer Research Ltd. Recombinant trypanosoma cruzi cells useful as anti-cancer immune agents
US20130287786A1 (en) 2010-12-29 2013-10-31 Theodorus Petrus Maria Schetters Canine babesiosis vaccine antigen
US10864260B2 (en) 2015-10-28 2020-12-15 Universidad Complutense De Madrid Neospora vaccine composition
EP3478301A4 (en) 2016-06-29 2020-04-22 Ramot at Tel-Aviv University Ltd. Manipulated parasites for the delivery of protein to the central nervous system (CNS)
WO2019140136A1 (en) * 2018-01-10 2019-07-18 University Of Washington Malarial vaccination methods and regimens
CN112567017B (zh) * 2018-05-15 2024-08-23 沃尔特及伊莱萨霍尔医学研究院 寄生虫疫苗
CN109825514A (zh) * 2019-01-24 2019-05-31 华中农业大学 田鼠巴贝斯虫gpi10基因及其编码的蛋白和应用
CN110922491B (zh) * 2019-12-17 2021-08-27 河南科技大学 一种肉孢子虫融合抗原、编码基因、间接elisa抗体检测试剂盒及其应用
US12144853B2 (en) 2020-01-13 2024-11-19 University Of Washington Targeted vaccination in the liver

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000507089A (ja) * 1995-12-22 2000-06-13 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 組換えバキュロウイルスの生産

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5756662A (en) * 1995-03-14 1998-05-26 Corixa Corporation Compounds and methods for the detection of T. cruzi infection
WO1998037185A2 (en) * 1997-02-20 1998-08-27 The Board Of Regents Of The University Of Texas System Vectors for controlled gene expression
US6596508B2 (en) * 1999-03-19 2003-07-22 National Research Council Of Canada CRE-inducible expression system
EP1150709A2 (en) * 1999-05-04 2001-11-07 Rima W. Mcleod Anti-microbial agents, diagnostic reagents, and vaccines based on apicomplexan parasite components

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000507089A (ja) * 1995-12-22 2000-06-13 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 組換えバキュロウイルスの生産

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019156751A (ja) * 2018-03-13 2019-09-19 共立製薬株式会社 反芻動物のネオスポラ感染症に対するワクチン製剤
JP7032965B2 (ja) 2018-03-13 2022-03-09 共立製薬株式会社 反芻動物のネオスポラ感染症に対するワクチン製剤

Also Published As

Publication number Publication date
AU2003270274B2 (en) 2009-03-19
CA2498604A1 (en) 2004-04-01
US20050244437A1 (en) 2005-11-03
AU2003270274A1 (en) 2004-04-08
CN100393866C (zh) 2008-06-11
BR0313994A (pt) 2005-07-19
EP1543028A2 (en) 2005-06-22
WO2004026903A3 (en) 2004-06-03
CN1681842A (zh) 2005-10-12
WO2004026903A2 (en) 2004-04-01

Similar Documents

Publication Publication Date Title
JP2006518184A (ja) 弱毒寄生虫生ワクチン
Ding et al. In ovo vaccination with the Eimeria tenella EtMIC2 gene induces protective immunity against coccidiosis
US5597571A (en) Eimeria antigenic composition which elicits antibodies against avian coccidiosis
Petersen et al. Biology of toxoplasmosis
Li et al. Transgenic Eimeria mitis expressing chicken interleukin 2 stimulated higher cellular immune response in chickens compared with the wild-type parasites
Klotz et al. Identification of Eimeria tenella genes encoding for secretory proteins and evaluation of candidates by DNA immunisation studies in chickens
US9250239B2 (en) Compositions and methods for detecting microbial infections
MXPA04000127A (es) Acidos nucleicos que codifican a antigenos recombinantes de gametocitos de eimeria maxima de 56 y de 86 kda y sus usos.
WO2000046381A1 (en) Recombinant expression of heterologous nucleic acids in protozoa
WO2024250024A2 (en) Vaccine for cats to block toxoplasma oocyst shedding and transmission
EP2598163B1 (en) Recombinant trypanosoma theileri parasite
JP4898432B2 (ja) 遺伝子組換え植物による抗原虫病経口ワクチン
Qu et al. CRISPR-Cas9-based method for isolating microgametes of Eimeria tenella
Soete et al. The importance of reverse genetics in determining gene function in apicomplexan parasites
CN111032079A (zh) 双重减毒肝晚期疟原虫及相关组合物和方法
WO2013113865A1 (en) Eimeria vector vaccine for campylobacter jejuni
JP7649504B2 (ja) マラリアワクチン及びマラリア予防・治療方法
US9603914B2 (en) Mutant strains of Neospora and uses thereof
US20100093062A1 (en) Transfection system for perkinsus species
Kopko Response of chickens to different immunizing strategies using a refractile body antigen of Eimeria tenella
CN1171813A (zh) 运输系统
Adhikari Construction of transfection vectors to target plasmodium berghei Apical membrane antigen1 (AMA1) and autophagy related 18 (ATG18) genes, and characterization of recombinant parasites
Tang et al. Construction of transgenic Eimeria tenella expressing Eimeria maxima profilin
Wirth New Strategies for Drug Discovery and Development for Plasmodium Falciparum

Legal Events

Date Code Title Description
A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20061222

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090324

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20090617

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20090624

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20090924

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20091020

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100219

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20100407

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100706

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100928

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20101005